cyproheptadine and mianserin

cyproheptadine has been researched along with mianserin in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199013 (35.14)18.7374
1990's12 (32.43)18.2507
2000's8 (21.62)29.6817
2010's3 (8.11)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Donné-Op den Kelder, GM; ter Laak, AM; Timmerman, H; Venhorst, J1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA1
Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R1
Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ1
Buck, LB; Petrascheck, M; Ye, X1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Segal, M1
Barnett, A; Malick, JB1
Colpaert, FC; Janssen, PA; Niemegeers, CJ1
Flückiger, E; Markó, M1
Edamura, N; Kizawa, Y; Maruyama, C; Murakami, H; Sano, M; Yamazaki, A1
Carpenter, DO; Evans, ML; Hartig, PR; Kadan, MJ1
Agresta, CA; Freeman, GM; Liu, ZJ; Maitland-Heriot, RP; Puniak, MA; Salzman, SK1
Fermanian, J; Frances, H; Lienard, C1
DeNoble, VJ; Spencer, KR; Strek, KF1
Bush, LR1
Braszko, JJ; Maciejewski, A; Majewski, K; Wisniewski, K1
Christensson, E; Gerlach, J; Korsgaard, S1
Anthony, M1
Fink, H; Gold, R; Morgenstern, R1
Sansone, M1
Riku, MK; Semenova, TP1
Marwood, JF; Okoro, EO1
Houchi, H; Ishimura, Y; Minakuchi, K; Morita, K; Oka, M; Takasugi, M; Tamaki, T; Yoshizumi, M1
Smythe, TL; Stricker, SA1
Nath, C; Srivastava, SK1
Poyurovsky, M; Weizman, A1
Escartín-Pérez, RE; López-Alonso, VE; Mancilla-Díaz, JM1
Butler, MC; Di Battista, M; Warden, M1
Baydemir, C; Dogan, AE; Erol, K; Kilic, FS1
Bolleddula, J; Chowdhury, S; Kato, S; Miyata, Y; Plesescu, M; Shah, A; Zhu, X1

Reviews

1 review(s) available for cyproheptadine and mianserin

ArticleYear
Serotonin antagonists.
    Australian and New Zealand journal of medicine, 1984, Volume: 14, Issue:6

    Topics: Cyproheptadine; Depression; Ergotamine; Humans; Hypertension; Ketanserin; Lisuride; Methysergide; Mianserin; Migraine Disorders; Piperidines; Pizotyline; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vascular Diseases

1984

Other Studies

36 other study(ies) available for cyproheptadine and mianserin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
The histamine H1-receptor antagonist binding site. A stereoselective pharmacophoric model based upon (semi-)rigid H1-antagonists and including a known interaction site on the receptor.
    Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17

    Topics: Binding Sites; Histamine H1 Antagonists; Models, Molecular; Molecular Conformation; Stereoisomerism

1995
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
First pharmacophoric hypothesis for 5-HT7 antagonism.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship

2000
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:2

    Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles

2003
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
5-HT antagonists in rat hippocampus.
    Brain research, 1976, Feb-13, Volume: 103, Issue:1

    Topics: Acetylcholine; Animals; Bicuculline; Cinanserin; Cyproheptadine; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Lysergic Acid Diethylamide; Male; Methiothepin; Methysergide; Mianserin; Norepinephrine; Picrotoxin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical

1976
The role of serotonergic pathways in isolation-induced aggression in mice.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Amidines; Animals; Cinanserin; Cyproheptadine; Depression, Chemical; Drug Interactions; Fenclonine; Humans; Male; Methiothepin; Methysergide; Mianserin; Mice; Motor Activity; Neural Pathways; Phenyl Ethers; Physostigmine; Pizotyline; Receptors, Serotonin; Scopolamine; Serotonin; Social Isolation

1976
In vivo evidence of partial agonist activity exerted by purported 5-hydroxytryptamine antagonists.
    European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4

    Topics: Animals; Cyproheptadine; Generalization, Stimulus; Lysergic Acid Diethylamide; Mescaline; Methysergide; Mianserin; Prejudice; Quipazine; Rats; Serotonin; Serotonin Antagonists

1979
Inhibition of ovulation in rats by antagonists to serotonin and by a new tricyclic compound.
    Experientia, 1976, Apr-15, Volume: 32, Issue:4

    Topics: Animals; Cycloheptanes; Cyproheptadine; Female; Ketotifen; Luteinizing Hormone; Methysergide; Mianserin; Ovary; Ovulation; Pituitary Gland, Anterior; Rats; Serotonin Antagonists; Thiophenes

1976
Possible site of action of 2-methylserotonin in inducing relaxation of acetylcholine-induced contraction in the molluscan (Mytilus edulis) smooth muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:2

    Topics: Acetylcholine; Animals; Bivalvia; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dose-Response Relationship, Drug; Indoles; Ketanserin; Mianserin; Muscle Relaxation; Muscle, Smooth; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes; Tropisetron

1992
Correlation of 125I-LSD autoradiographic labeling with serotonin voltage clamp responses in Aplysia neurons.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:1

    Topics: Acetylcholine; Animals; Aplysia; Cyproheptadine; Electric Conductivity; Ganglia; In Vitro Techniques; Iodine Radioisotopes; Ion Channels; Lysergic Acid Diethylamide; Membrane Potentials; Mianserin; Neurons; Radioligand Assay; Receptors, Serotonin; Serotonin

1991
The serotonin antagonist mianserin improves functional recovery following experimental spinal trauma.
    Annals of neurology, 1991, Volume: 30, Issue:4

    Topics: Analysis of Variance; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Ketanserin; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spinal Cord Injuries

1991
Improvement of the isolation-induced social behavioural deficit involves activation of the 5-HT1B receptors.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:1

    Topics: Animals; Cyproheptadine; Escape Reaction; Indoles; Male; Mianserin; Mice; Mice, Inbred Strains; Penbutolol; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Social Behavior; Social Isolation; Spiperone; Tropisetron

1990
Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Animals; Avoidance Learning; Cyproheptadine; Dose-Response Relationship, Drug; Fluoxetine; Hypoxia; Ketanserin; Male; Methysergide; Mianserin; Rats; Rats, Inbred Strains; Serotonin; Zimeldine

1989
Effects of the serotonin antagonists, cyproheptadine, ketanserin and mianserin, on cyclic flow reductions in stenosed canine coronary arteries.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Cyproheptadine; Dogs; Epinephrine; Female; Hemodynamics; Ketanserin; Male; Mianserin; Periodicity; Platelet Aggregation; Serotonin

1987
Effect of angiotensin II on some behavioral and neurochemical measures of the central serotonine system.
    Biomedica biochimica acta, 1985, Volume: 44, Issue:9

    Topics: 5-Hydroxytryptophan; Angiotensin II; Animals; Behavior, Animal; Brain Chemistry; Cyproheptadine; Electroshock; Fenfluramine; Hydroxylation; Injections, Intraventricular; Kinetics; Male; Mianserin; Physostigmine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
Behavioral aspects of serotonin-dopamine interaction in the monkey.
    European journal of pharmacology, 1985, Dec-03, Volume: 118, Issue:3

    Topics: Animals; Chlorocebus aethiops; Cyproheptadine; Dextroamphetamine; Dopamine; Dyskinesia, Drug-Induced; Female; Haloperidol; Male; Mianserin; Motor Activity; Piperidines; Serotonin; Serotonin Antagonists

1985
Effects of atypical antidepressants on LSD potentiated apomorphine hypermotility in rats.
    Acta biologica et medica Germanica, 1980, Volume: 39, Issue:8-9

    Topics: Animals; Apomorphine; Cyproheptadine; Lysergic Acid Diethylamide; Male; Mianserin; Motor Activity; Piperidines; Pizotyline; Rats; Serotonin Antagonists

1980
Opposite effects of chlordiazepoxide and serotonin receptor antagonists on morphine-induced locomotor stimulation in mice.
    Psychopharmacology, 1982, Volume: 78, Issue:1

    Topics: Animals; Chlordiazepoxide; Cyproheptadine; Dibenzazepines; Male; Mianserin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Motor Activity; Receptors, Serotonin

1982
[The role of the interaction of various types of serotonin- and alpha 2-adrenoreceptors in regulating audiogenic seizures in DBA/2 mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 119, Issue:4

    Topics: Acoustic Stimulation; Adrenergic alpha-2 Receptor Antagonists; Animals; Cyproheptadine; Mianserin; Mice; Mice, Inbred DBA; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Seizures; Serotonin Antagonists; Yohimbine

1995
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997
Serotonin increases Na(+)-dependent Ca2+ efflux from bovine adrenal chromaffin cells in culture.
    Neuroscience letters, 1997, Feb-14, Volume: 223, Issue:1

    Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Cyproheptadine; Dose-Response Relationship, Drug; Intracellular Membranes; Mianserin; Osmolar Concentration; Serotonin; Serotonin Antagonists; Sodium

1997
Multiple triggers of oocyte maturation in nemertean worms: the roles of calcium and serotonin.
    The Journal of experimental zoology, 2000, Aug-01, Volume: 287, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; Cyproheptadine; Dose-Response Relationship, Drug; Egtazic Acid; Mianserin; Microscopy, Confocal; Nematoda; Oocytes; Seawater; Serotonin; Serotonin Antagonists; Video Recording

2000
The differential effects of calcium channel blockers in the behavioural despair test in mice.
    Pharmacological research, 2000, Volume: 42, Issue:4

    Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil

2000
Serotonin-based pharmacotherapy for acute neuroleptic-induced akathisia: a new approach to an old problem.
    The British journal of psychiatry : the journal of mental science, 2001, Volume: 179

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Buspirone; Clinical Trials as Topic; Cyproheptadine; Humans; Mianserin; Ritanserin; Serotonin Agents

2001
The effects of 5-HT on feeding behaviour in mianserin- or cyproheptadine-pretreated rats.
    Eating and weight disorders : EWD, 2003, Volume: 8, Issue:4

    Topics: Analysis of Variance; Animals; Cyproheptadine; Dietary Carbohydrates; Feeding Behavior; Male; Mianserin; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists

2003
Sertraline-induced serotonin syndrome followed by mirtazapine reaction.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Aug-16, Volume: 34, Issue:6

    Topics: Adult; Antidepressive Agents; Cyproheptadine; Depressive Disorder, Major; Humans; Male; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome; Sertraline; Treatment Outcome

2010
The acute effects of mirtazapine on pain related behavior in healthy animals.
    Neurosciences (Riyadh, Saudi Arabia), 2011, Volume: 16, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Arginine; Behavior, Animal; Cyproheptadine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Hippocampus; In Vitro Techniques; Male; Mianserin; Mice; Mirtazapine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin Antagonists

2011
Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10

    Topics: Animals; Bile; Biotransformation; Carbamates; Cyproheptadine; Drug Evaluation, Preclinical; Hepatobiliary Elimination; Hepatocytes; Humans; Liver; Loratadine; Male; Mianserin; Mice; Transplantation Chimera

2020