cyproheptadine and loratadine

cyproheptadine has been researched along with loratadine in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199034 (36.56)18.7374
1990's40 (43.01)18.2507
2000's9 (9.68)29.6817
2010's8 (8.60)24.3611
2020's2 (2.15)2.80

Authors

AuthorsStudies
Morphy, R; Rankovic, Z1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Small, P1
Kaliner, MA1
Bergman, U; Nyman, K1
Barkley, AS; Millard, LG; Shall, L; Thompson, DA1
O'Hanlon, JF; Ramaekers, JG; Uiterwijk, MM1
Giös, I; Hägermark, O; Wahlgren, CF1
Andreoli, A; Boner, AL; Castellani, C; Marchesi, E; Richelli, C1
Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D1
Abu Shareeah, AM1
Casciano, CN; Cayen, MN; Clement, RP; Parkinson, A1
Becker, AB; Lukowski, JL; Simons, FE; Simons, KJ1
Fletcher, MP; Ryhal, BT1
Soter, NA1
Gillardin, JM; Gommeren, W; Janssen, PA; Janssen, PF; Leysen, JE; Sanz, G; Schotte, A1
Humphreys, F; Hunter, JA1
Frølund, L1
Basco, LK; Le Bras, J; Ringwald, P1
Buscaglia, S; Canonica, GW; Ciprandi, G; Marchesi, E; Pesce, GP1
Chapman, RW; Egan, RW; Kreutner, W; Mauser, PJ1
Peters, SP1
Andersson, M; Baumgarten, C; Nolte, H; Pipkorn, U1
Paul, E1
Pedersen, MF1
Belaich, S; Bruttmann, G; DeGreef, H; Lachapelle, JM; Paul, E; Pedrali, P; Tennstedt, D1
Coulie, P; Ghys, L; Rihoux, JP1
Bousquet, J; Chanal, I; Lemonier, C; Michel, FB; Skassa-Brociek, W1
McMillan, JL; Simons, FE; Simons, KJ1
Woodward, JK2
Kaiser, HB1
Simons, FE2
Ekong, R; Pan, XQ; Peters, W; Robinson, BL; Warhurst, DC1
Katelaris, C1
Hammarlund, A; Olsson, P; Pipkorn, U1
Irander, K; Odkvist, LM; Ohlander, B1
Halstenson, CE; Hilbert, J; Matzke, GR; Opsahl, JA; Perentesis, G; Radwanski, E; Zampaglione, N1
Longo, G; Marchesi, E; Poli, F; Ventura, A1
Etholm, B; Frølund, L; Irander, K; Johannessen, TA; Odkvist, L; Ohlander, B; Weeke, B1
Holgate, ST; Town, GI1
Chapman, RW; Gulbenkian, A; Kreutner, W; Siegel, MI1
Bousquet, J; Chanal, I; Lebel, B; Michel, FB; Morel, A1
McCluskey, M; Temple, DM1
Banov, CH; Bodman, SF; Chervinsky, P; Dockhorn, RJ; Jarmoszuk, I; McGeady, SJ; Nathan, RA; Pinnas, JL; Storms, WW; Zeitz, HJ1
Clissold, SP; Goa, KL; Sorkin, EM1
Bindslev-Jensen, C; Dirksen, A; Frølund, L1
Barenholtz, HA; McLeod, DC1
Bronsky, EA; Grossman, J; Lanier, BQ; Linzmayer, MI; Moss, BA; Schenkel, EJ; Selner, JC1
Berkowitz, RB; Connell, JT; Dietz, AJ; Greenstein, SM; Tinkelman, DG1
Dirksen, A; Engel, T; Frølund, L; Heinig, JH; Svendsen, UG; Weeke, B1
Bruttmann, G; Charpin, D; Germouty, J; Horak, F; Kunkel, G; Wittmann, G1
Herakleous, M; Kontou-Fili, K; Paleologos, G1
Marzanatti, M; Monopoli, A; Ongini, E; Trampus, M1
Andreoli, A; Boner, AL; Marchesi, E; Miglioranzi, P; Richelli, C1
Bedard, PM; Del Carpio, J; Gutkowski, A; Hebert, J; Kabbash, L; Nedilski, M; Prevost, M; Schulz, J; Turenne, Y1
Amkraut, HJ; Batenhorst, AS; Batenhorst, RL; Foster, TS; Graves, DA; Gural, RP; Kung, M1
Koshorek, G; Roehrs, T; Roth, T; Sicklesteel, J; Zorick, F1
Bradley, CM; Nicholson, AN1
Bruttmann, G; Christophers, E; Frølund, L; Horak, F; Pedrali, P; Weeke, B; Wolff, HH1
Bedard, P; Del Carpio, J; Gutkowski, A; Hebert, J; Prevost, M; Schulz, J; Turenne, Y; Yeadon, C1
Bernstein, DI; Brigante, JR; Fox, RW; Green, AW; Izuno, GT; Monroe, EW; Pleskow, WW; Willis, I1
O'Hanlon, JF1
Oei, HD1
Magatti, CV; Popper, TL; Vashi, DB; Villani, FJ; Wong, J1
Bergner, A; Connell, JT; Dockhorn, RJ; Falliers, CJ; Grabiec, SV; Shellenberger, MK; Weiler, JM1
Hilbert, J; Radwanski, E; Symchowicz, S; Zampaglione, N1
Hilbert, J; Luc, V; Perentesis, G; Radwanski, E; Symchowicz, S; Weglein, R; Zampaglione, N1
Bousquet, J; Lherminier, M; Michel, FB; Montes, F; Schwab, D; Skassa-Brociek, W; Verdier, M1
Affrime, MB; Hilbert, J; Perentesis, G; Radwanski, E; Symchowicz, S; Zampaglione, N1
Dyer, JG; Gural, R; Kassem, N; Robillard, N; Roman, I1
de Jong, R; Gaillard, AW; Gruisen, A1
Schultze-Wernighaus, G1
Brazís, P; de Mora, F; Merlos, M; Puigdemont, A; Queralt, M1
Dumur, JP; Izquierdo, I; Pérez, I; Saint-Martin, F1
Camelo-Nunes, IC1
Carbó, ML; Izquierdo, I; Merlos, M; Nadal, T; Peña, J; Solans, A1
Antonijoan, R; Barbanoj, M; Carbó, ML; Donado, E; Izquierdo, I; Merlos, M; Nadal, T; Peña, J; Solans, A1
Fan, G; Hong, Z; Wei, H; Wen, J; Wu, Y1
Srinivas, NR1
Laraba-Djebari, F; Sebia-Amrane, F1
Bennett, C; Carter, B; Cohen, SN; Sharma, M1
Ding, L; Gu, P; Li, Q; Liu, B; Pan, L; Sun, C; Wu, C; Zhang, J1
Barkai, L; Izquierdo, I; Maurer, M; Mezei, G; Mitha, E; Potter, P; Santamaría, E1
Antonijoan, R; Campo, C; Coimbra, J; García-Gea, C; Gich, I; Labeaga, L; Puntes, M; Valiente, R1
Kannappan, V; Kanthiah, S1
Bosma, R; Bushby, N; de Esch, IJ; de Graaf, C; Kooistra, AJ; Kuhne, S; Leurs, R; Sheppard, RJ; van den Bor, J; Vischer, HF; Wang, Z; Waring, MJ; Wijtmans, M1
Bolleddula, J; Chowdhury, S; Kato, S; Miyata, Y; Plesescu, M; Shah, A; Zhu, X1
Halatsch, ME; Kast, RE; Rosell, R1

Reviews

13 review(s) available for cyproheptadine and loratadine

ArticleYear
Designed multiple ligands. An emerging drug discovery paradigm.
    Journal of medicinal chemistry, 2005, Oct-20, Volume: 48, Issue:21

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Chemistry, Pharmaceutical; Dopamine D2 Receptor Antagonists; Drug Design; Humans; Ligands; Metabolic Diseases; Peroxisome Proliferator-Activated Receptors; Receptors, Histamine H1; Selective Serotonin Reuptake Inhibitors

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Nonsedating antihistamines: pharmacology, clinical efficacy and adverse effects.
    American family physician, 1992, Volume: 45, Issue:3

    Topics: Astemizole; Cyproheptadine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadine; Terfenadine

1992
The second-generation antihistamines. What makes them different?
    Postgraduate medicine, 1991, May-01, Volume: 89, Issue:6

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyproheptadine; Education, Medical, Continuing; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Loratadine; Terfenadine

1991
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine

1990
Recent advances in H1-receptor antagonist treatment.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Terfenadine; Urticaria

1990
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, Allergic, Seasonal; Triprolidine; Urticaria

1990
Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy.
    Drugs, 1989, Volume: 37, Issue:1

    Topics: Animals; Common Cold; Cyproheptadine; Female; Humans; Loratadine; Male; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Urticaria

1989
Loratadine: a nonsedating antihistamine with once-daily dosing.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:6

    Topics: Cyproheptadine; Humans; Hypersensitivity; Loratadine

1989
Pharmacology and toxicology of nonclassical antihistamines.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cyproheptadine; Drug Administration Schedule; Histamine H1 Antagonists; Humans; Loratadine; Sleep Stages; Terfenadine

1988
New antihistamines: a critical view.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine

2006
H1-antihistamines for chronic spontaneous urticaria.
    The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Controlled Trials as Topic; Urticaria

2014
OPALS: A New Osimertinib Adjunctive Treatment of Lung Adenocarcinoma or Glioblastoma Using Five Repurposed Drugs.
    Cells, 2021, 05-10, Volume: 10, Issue:5

    Topics: Acrylamides; Adenocarcinoma of Lung; Aniline Compounds; Animals; Azithromycin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemotherapy, Adjuvant; Cyproheptadine; Drug Repositioning; Drug Resistance, Neoplasm; ErbB Receptors; Glioblastoma; Humans; Loratadine; Lung Neoplasms; Mice; Neoplasm Metastasis; Pyrimethamine; Spironolactone

2021

Trials

50 trial(s) available for cyproheptadine and loratadine

ArticleYear
Suppression of epicutaneous reactivity by terfenadine and loratadine.
    Annals of allergy, 1992, Volume: 68, Issue:1

    Topics: Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Rhinitis, Allergic, Seasonal; Skin; Skin Tests; Terfenadine

1992
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:7

    Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Models, Biological; Single-Blind Method; Skin; Skin Tests; Terfenadine

1992
Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Adult; Automobile Driving; Cetirizine; Cyproheptadine; Double-Blind Method; Electroencephalography; Ethanol; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Psychological Tests; Psychometrics; Psychomotor Performance

1992
Inhibitory effect of loratadine and clemastine on histamine release in human skin.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Clemastine; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine Release; Humans; Loratadine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Skin

1992
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
    Allergy, 1992, Volume: 47, Issue:2 Pt 1

    Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Male; Rhinitis, Allergic, Seasonal; Single-Blind Method

1992
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine

1992
Comparative efficacy of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    International journal of dermatology, 1992, Volume: 31, Issue:5

    Topics: Adult; Chronic Disease; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Male; Pruritus; Remission Induction; Terfenadine; Time Factors; Urticaria

1992
Comparison of the effects of single doses of the new H1-receptor antagonists loratadine and terfenadine versus placebo in children.
    The Journal of pediatrics, 1991, Volume: 118, Issue:2

    Topics: Benzhydryl Compounds; Child; Cyproheptadine; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Patch Tests; Rhinitis, Allergic, Perennial; Terfenadine

1991
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.
    The British journal of dermatology, 1991, Volume: 125, Issue:4

    Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors

1991
Efficacy of an oral antihistamine, loratadine, as compared with a nasal steroid spray, beclomethasone dipropionate, in seasonal allergic rhinitis.
    Clinical otolaryngology and allied sciences, 1991, Volume: 16, Issue:6

    Topics: Administration, Intranasal; Administration, Oral; Adult; Aged; Beclomethasone; Cyproheptadine; Double-Blind Method; Eye; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nose; Poaceae; Pollen; Pruritus; Rhinitis, Allergic, Seasonal; Sneezing; Time Factors; Trees

1991
Protective effect of loratadine on specific conjunctival provocation test.
    International archives of allergy and applied immunology, 1991, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Aged; Conjunctiva; Conjunctivitis, Allergic; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Provocation Tests; Placebos

1991
Suppressive effect of loratadine on allergen-induced histamine release in the nose.
    Allergy, 1991, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Allergens; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Loratadine; Male; Nasal Provocation Tests; Nose; Rhinitis, Allergic, Seasonal

1991
[Treatment of pruritic skin diseases with loratadine. Results of an open multicenter study].
    Fortschritte der Medizin, 1991, Mar-10, Volume: 109, Issue:7

    Topics: Adolescent; Adult; Aged; Cyproheptadine; Drug Evaluation; Female; Histamine Antagonists; Humans; Loratadine; Male; Middle Aged; Pruritus; Skin Diseases

1991
Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    Annals of allergy, 1990, Volume: 64, Issue:2 Pt 2

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Cyproheptadine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Middle Aged; Terfenadine; Urticaria

1990
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
    Annals of allergy, 1990, Volume: 65, Issue:2

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic

1990
Lack of subsensitivity to loratadine during long-term dosing during 12 weeks.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:2

    Topics: Adult; Allergens; Cyproheptadine; Double-Blind Method; Drug Tolerance; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Skin Tests

1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria

1990
Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis.
    Asian Pacific journal of allergy and immunology, 1990, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Cyproheptadine; Double-Blind Method; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Seasonal

1990
Blood flow in histamine- and allergen-induced weal and flare responses, effects of an H1 antagonist, alpha-adrenoceptor agonist and a topical glucocorticoid.
    Allergy, 1990, Volume: 45, Issue:1

    Topics: Administration, Topical; Adult; Allergens; Antigen-Antibody Reactions; Betamethasone; Clobetasol; Cyproheptadine; Double-Blind Method; Ephedrine; Female; Histamine; Histamine Antagonists; Humans; Lasers; Loratadine; Male; Random Allocation; Regional Blood Flow; Skin; Skin Tests

1990
Treatment of hay fever with loratadine--a new non-sedating antihistamine.
    Allergy, 1990, Volume: 45, Issue:2

    Topics: Clemastine; Cyproheptadine; Double-Blind Method; Drug Evaluation; Female; Histamine Antagonists; Humans; Loratadine; Male; Random Allocation; Rhinitis, Allergic, Seasonal

1990
[Loratadine and dexchlorpheniramine in the treatment of perennial allergic rhinitis in pediatric patients].
    Minerva pediatrica, 1990, Volume: 42, Issue:5

    Topics: Age Factors; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Female; Histamine Antagonists; Humans; Infant; Loratadine; Male; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Stereoisomerism

1990
A multicentre study of loratadine, clemastine and placebo in patients with perennial allergic rhinitis.
    Allergy, 1990, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Aged; Clemastine; Cyproheptadine; Double-Blind Method; Female; Histamine Antagonists; Humans; Loratadine; Male; Medical Records; Middle Aged; Multicenter Studies as Topic; Pyrrolidines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Time Factors

1990
Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 1

    Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Cyproheptadine; Female; Histamine; Histamine Antagonists; Humans; Loratadine; Methacholine Chloride; Middle Aged; Skin; Skin Tests

1990
Antiallergic activity of H1-receptor antagonists assessed by nasal challenge.
    The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:5 Pt 1

    Topics: Adult; Benzhydryl Compounds; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Histamine Release; Humans; Loratadine; Nasal Provocation Tests; Pollen; Prostaglandin D2; Rhinitis, Allergic, Seasonal; Terfenadine

1988
SCH 434: a new antihistamine/decongestant for seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Child; Cyproheptadine; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Multicenter Studies as Topic; Nasal Decongestants; Pseudoephedrine; Rhinitis, Allergic, Seasonal

1989
Loratadine-pseudoephedrine combination versus placebo in patients with seasonal allergic rhinitis.
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Cyproheptadine; Drug Combinations; Ephedrine; Female; Histamine Antagonists; Humans; Loratadine; Male; Middle Aged; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal

1989
The effectiveness of the nonsedating antihistamine loratadine plus pseudoephedrine in the symptomatic management of the common cold.
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Common Cold; Cyproheptadine; Double-Blind Method; Drug Combinations; Ephedrine; Female; Histamine Antagonists; Humans; Loratadine; Male; Middle Aged; Multicenter Studies as Topic

1989
Effect of a non-sedative antihistaminic (loratadine) in moderate asthma. A double-blind controlled clinical crossover-trial.
    Allergy, 1989, Volume: 44, Issue:8

    Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine Antagonists; Humans; Loratadine; Male; Middle Aged; Peak Expiratory Flow Rate

1989
Evaluation of the efficacy and safety of loratadine in perennial allergic rhinitis.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:2 Pt 1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Child; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Mucosa; Placebos; Rhinitis, Allergic, Perennial; Terfenadine

1989
Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Middle Aged; Random Allocation; Skin

1989
Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis.
    Allergy, 1989, Volume: 44, Issue:6

    Topics: Administration, Oral; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Intradermal Tests; Loratadine; Male; Pollen; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal

1989
Efficacy and safety of loratadine (10 mg once daily), terfenadine (60 mg twice daily), and placebo in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:5 Pt 1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Cyproheptadine; Double-Blind Method; Drug Administration Schedule; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine

1989
Pharmacologic evaluation of loratadine (SCH 29851), chlorpheniramine and placebo.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:2

    Topics: Adult; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Humans; Intradermal Tests; Loratadine; Male; Random Allocation

1986
Sedative effects of antihistamines.
    The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:1

    Topics: Adult; Cyproheptadine; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Male; Sleep

1987
A multicentric study of loratadine, terfenadine and placebo in patients with seasonal allergic rhinitis.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Child; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Random Allocation; Rhinitis, Allergic, Seasonal; Terfenadine

1988
Comparison of the efficacy and safety of loratadine, terfenadine, and placebo in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:5 Pt 1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Loratadine; Middle Aged; Placebos; Random Allocation; Rhinitis, Allergic, Seasonal; Terfenadine

1988
Efficacy and safety of loratadine (10 mg once daily) in the management of idiopathic chronic urticaria.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:1 Pt 1

    Topics: Chronic Disease; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Humans; Loratadine; Random Allocation; Urticaria

1988
Antihistamines and driving safety.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Automobile Driving; Benzhydryl Compounds; Cyproheptadine; Double-Blind Method; Ethanol; Histamine H1 Antagonists; Humans; Loratadine; Male; Psychomotor Performance; Sleep Stages; Terfenadine

1988
Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action.
    Annals of allergy, 1988, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Clinical Trials as Topic; Cyproheptadine; Dose-Response Relationship, Drug; Double-Blind Method; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Placebos; Rhinitis, Allergic, Seasonal; Time Factors

1988
Safety and efficacy of loratadine (Sch-29851): a new non-sedating antihistamine in seasonal allergic rhinitis.
    Annals of allergy, 1987, Volume: 58, Issue:6

    Topics: Capsules; Clemastine; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Histamine Antagonists; Humans; Loratadine; Placebos; Random Allocation; Rhinitis, Allergic, Seasonal; Time Factors

1987
Pharmacokinetics and dose proportionality of loratadine.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:9

    Topics: Administration, Oral; Adult; Cyproheptadine; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Loratadine; Male; Radioimmunoassay; Random Allocation

1987
Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Humans; Loratadine; Male; Middle Aged; Phenothiazines; Placebos; Rhinitis, Allergic, Seasonal

1988
Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals.
    Annals of allergy, 1988, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Dose-Response Relationship, Drug; Histamine; Humans; Hypnotics and Sedatives; Loratadine; Male; Urticaria

1988
The influence of antihistamines on human performance.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:3

    Topics: Administration, Oral; Adult; Benzhydryl Compounds; Clemastine; Cyproheptadine; Diazepam; Double-Blind Method; Humans; Loratadine; Male; Psychomotor Performance; Pyrrolidines; Reaction Time; Terfenadine; Time Factors

1988
[Disodium cromoglycate in comparison with antihistaminics (loratadine) in seasonal allergic rhinitis].
    Zeitschrift fur Hautkrankheiten, 1988, Volume: 63 Suppl 4

    Topics: Adult; Clinical Trials as Topic; Cromolyn Sodium; Cyproheptadine; Histamine Antagonists; Humans; Loratadine; Pollen; Random Allocation; Rhinitis, Allergic, Seasonal

1988
A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis.
    Journal of investigational allergology & clinical immunology, 2004, Volume: 14, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Cross-Over Studies; Cyproheptadine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Platelet Activating Factor; Probability; Reference Values; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Treatment Outcome

2004
Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study.
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cyproheptadine; Female; Food-Drug Interactions; Histamine H1 Antagonists; Humans; Loratadine; Male; Tablets

2007
Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin at steady-state levels: a randomized, open-label, two-way, crossover, Phase I study.
    Clinical therapeutics, 2008, Volume: 30, Issue:9

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Azithromycin; Chromatography, High Pressure Liquid; Confidence Intervals; Cross-Over Studies; Cyproheptadine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Safety; Therapeutic Equivalency

2008
Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2016, Volume: 27, Issue:1

    Topics: Age Factors; Child; Child, Preschool; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Hungary; Loratadine; Male; Quality of Life; Remission Induction; South Africa; Time Factors; Treatment Outcome; Urticaria

2016
Comparative efficacy of bilastine, desloratadine and rupatadine in the suppression of wheal and flare response induced by intradermal histamine in healthy volunteers.
    Current medical research and opinion, 2017, Volume: 33, Issue:1

    Topics: Adult; Benzimidazoles; Cross-Over Studies; Cyproheptadine; Double-Blind Method; Female; Healthy Volunteers; Histamine; Histamine Antagonists; Humans; Injections, Intradermal; Loratadine; Male; Piperidines; Skin

2017

Other Studies

30 other study(ies) available for cyproheptadine and loratadine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
[Clarityn--a 2-year follow-up study and comparison with Teldanex].
    Lakartidningen, 1992, May-13, Volume: 89, Issue:20

    Topics: Benzhydryl Compounds; Cyproheptadine; Follow-Up Studies; Histamine H1 Antagonists; Humans; Loratadine

1992
[Severe adverse effect of the anti-allergy drug loratadine--warning against prolonged use of non-prescription drugs].
    Lakartidningen, 1992, Jun-17, Volume: 89, Issue:25

    Topics: Adolescent; Adolescent Behavior; Cyproheptadine; Dose-Response Relationship, Drug; Headache; Histamine H1 Antagonists; Humans; Loratadine; Male; Mental Disorders; Nonprescription Drugs; Time Factors; Vomiting

1992
Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice.
    Biochemical pharmacology, 1992, May-28, Volume: 43, Issue:10

    Topics: Animals; Cyproheptadine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Histamine Antagonists; Immunoblotting; Isoenzymes; Loratadine; Male; Mice; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Testosterone

1992
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:6 Pt 2

    Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Urticaria

1991
[Non-sedative antihistaminics and binding to central and peripheral H1 histamine receptors].
    Allergie et immunologie, 1991, Volume: 23, Issue:2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cerebellum; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Hydroxyzine; Kinetics; Loratadine; Lung; Organ Specificity; Protein Binding; Receptors, Histamine H1; Terfenadine

1991
Chloroquine-potentiating action of antihistaminics in Plasmodium falciparum in vitro.
    Annals of tropical medicine and parasitology, 1991, Volume: 85, Issue:2

    Topics: Animals; Chloroquine; Cyproheptadine; Drug Resistance; Drug Synergism; Histamine H1 Antagonists; Loratadine; Plasmodium falciparum

1991
Selective inhibition of peripheral histamine responses by loratadine and terfenadine.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: Animals; Benzhydryl Compounds; Bronchi; Cyproheptadine; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Injections, Intravenous; Injections, Intraventricular; Loratadine; Lung; Lung Compliance; Male; Methacholine Compounds; Terfenadine

1990
[Loratadine inhibits mediator liberation from a suspension of human pulmonary mast cells].
    Allergie et immunologie, 1991, Volume: 23, Issue:3

    Topics: Cyproheptadine; Depression, Chemical; Histamine Antagonists; Histamine Release; Humans; Loratadine; Lung; Mast Cells; Secretory Rate; SRS-A

1991
Computed phonetograms in adult patients with benign voice disorders before and after treatment with a nonsedating antihistamine (loratadine).
    Folia phoniatrica, 1991, Volume: 43, Issue:2

    Topics: Adult; Aged; Chronic Disease; Cyproheptadine; Female; Histamine Antagonists; Humans; Laryngitis; Loratadine; Male; Middle Aged; Signal Processing, Computer-Assisted; Sound Spectrography; Voice Disorders

1991
Pharmacology of antihistamines.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Time Factors

1990
The chemotherapy of rodent malaria. XLV. Reversal of chloroquine resistance in rodent and human Plasmodium by antihistaminic agents.
    Annals of tropical medicine and parasitology, 1990, Volume: 84, Issue:6

    Topics: Animals; Chloroquine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Resistance; Histamine Antagonists; Histamine H1 Antagonists; Humans; In Vitro Techniques; Ketotifen; Loratadine; Pizotyline; Plasmodium berghei; Plasmodium yoelii; Rats

1990
Pharmacokinetics of loratadine in patients with renal insufficiency.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adult; Cyproheptadine; Female; Humans; Kidney Failure, Chronic; Loratadine; Male; Middle Aged; Piperidines; Pyridines; Renal Dialysis; Time Factors

1990
Antiallergic activity of loratadine, a non-sedating antihistamine.
    Allergy, 1987, Volume: 42, Issue:1

    Topics: Animals; Benzhydryl Compounds; Bronchial Spasm; Calcium; Cyproheptadine; Guinea Pigs; Histamine Antagonists; Histamine Release; Hypersensitivity; In Vitro Techniques; Loratadine; Male; Mast Cells; Rats; SRS-A; Terfenadine

1987
Loratadine, an antihistamine, blocks antigen-and ionophore-induced leukotriene release from human lung in vitro.
    Prostaglandins, 1988, Volume: 35, Issue:4

    Topics: Antigens; Calcimycin; Cyproheptadine; Histamine H1 Antagonists; Histamine Release; Humans; In Vitro Techniques; Leukotrienes; Loratadine; Lung; SRS-A

1988
[Loratadine. A new, non-sedating antihistaminc agent].
    Ugeskrift for laeger, 1989, May-29, Volume: 151, Issue:22

    Topics: Cyproheptadine; Histamine Antagonists; Humans; Loratadine

1989
Effects of nonsedating histamine H1-antagonists on EEG activity and behavior in the cat.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: Animals; Astemizole; Behavior, Animal; Benzhydryl Compounds; Benzimidazoles; Cats; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Histamine Antagonists; Histamine H1 Antagonists; Loratadine; Male; Phenothiazines; Sleep; Terfenadine

1989
Loratadine, a non-sedating H1-receptor antagonist (antihistamine)
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Cyproheptadine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

1989
Studies on the central effects of the H1-antagonist, loratadine.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:4

    Topics: Adult; Brain; Cyproheptadine; Female; Histamine H1 Antagonists; Humans; Loratadine; Psychomotor Performance

1987
N-substituted 11-(4-piperidylene)-5,6-dihydro-11H-benzo-[5,6]cyclohepta [1,2-b]pyridines. Antihistamines with no sedating liability.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:9

    Topics: Animals; Chemical Phenomena; Chemistry; Cyproheptadine; Female; Guinea Pigs; Histamine Antagonists; Hypnotics and Sedatives; Loratadine; Male; Mice

1986
Loratadine: multiple-dose pharmacokinetics.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:7

    Topics: Adult; Cyproheptadine; Half-Life; Histamine Antagonists; Humans; Loratadine; Male; Radioimmunoassay

1987
Excretion of loratadine in human breast milk.
    Journal of clinical pharmacology, 1988, Volume: 28, Issue:3

    Topics: Adult; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Milk, Human; Piperidines; Pyridines

1988
In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:7

    Topics: Animals; Antibodies; Calcimycin; Cell Line; Concanavalin A; Cyproheptadine; Dogs; Histamine Antagonists; Histamine Release; Humans; Immunoglobulin E; Loratadine; Mast Cells; Skin; Thiazoles; Tumor Necrosis Factor-alpha

2000
Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers.
    Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2

    Topics: Adult; Asian People; Calibration; Chromatography, Liquid; Cyproheptadine; Drug Stability; Female; Formates; Freezing; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Methanol; Molecular Structure; Platelet Activating Factor; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tandem Mass Spectrometry; Time Factors; Water; Young Adult

2009
Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine.
    Primary care respiratory journal : journal of the General Practice Airways Group, 2009, Volume: 18, Issue:2

    Topics: Cyproheptadine; Cytochrome P-450 CYP3A; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Mutation; Polymorphism, Single Nucleotide

2009
Pharmaco-modulations of induced edema and vascular permeability changes by Vipera lebetina venom: inflammatory mechanisms.
    Inflammation, 2013, Volume: 36, Issue:2

    Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cromolyn Sodium; Crotalid Venoms; Cyproheptadine; Edema; Histamine Release; Ibuprofen; Indomethacin; Inflammation; Loratadine; Male; Mice; Serotonin; Vasodilation

2013
Development of a highly sensitive LC-MS/MS method for simultaneous determination of rupatadine and its two active metabolites in human plasma: Application to a clinical pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2015, Volume: 111

    Topics: Chromatography, Liquid; Cyproheptadine; Female; Formates; Humans; Loratadine; Male; Plasma; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tandem Mass Spectrometry

2015
D-Optimal mixture design optimization of an HPLC method for simultaneous determination of commonly used antihistaminic parent molecules and their active metabolites in human serum and urine.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:8

    Topics: Anti-Allergic Agents; Chromatography, High Pressure Liquid; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Limit of Detection; Loratadine; Solid Phase Extraction; Terfenadine

2017
Route to Prolonged Residence Time at the Histamine H
    Journal of medicinal chemistry, 2019, 07-25, Volume: 62, Issue:14

    Topics: Cyproheptadine; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Molecular Docking Simulation; Protein Binding; Receptors, Histamine H1; Time Factors

2019
Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10

    Topics: Animals; Bile; Biotransformation; Carbamates; Cyproheptadine; Drug Evaluation, Preclinical; Hepatobiliary Elimination; Hepatocytes; Humans; Liver; Loratadine; Male; Mianserin; Mice; Transplantation Chimera

2020