cyproheptadine and hydroxyzine

cyproheptadine has been researched along with hydroxyzine in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199022 (47.83)18.7374
1990's16 (34.78)18.2507
2000's3 (6.52)29.6817
2010's5 (10.87)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Richelson, E1
Tindall, JP1
Garovoy, MR; Kupor, LR; McPhaul, JJ; Mullins, JD1
Cohan, R; Leifer, KN; Rhoades, RB; Wittig, HJ1
Highet, AS; Titterington, DM1
Czarny, D1
Baraf, CS1
Barkley, AS; Millard, LG; Shall, L; Thompson, DA1
O'Hanlon, JF; Ramaekers, JG; Uiterwijk, MM1
Crowe, MJ; Guin, JD; Parker, RK1
Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D1
Fletcher, MP; Ryhal, BT1
Soter, NA2
Gillardin, JM; Gommeren, W; Janssen, PA; Janssen, PF; Leysen, JE; Sanz, G; Schotte, A1
Humphreys, F; Hunter, JA1
Coulie, P; Ghys, L; Rihoux, JP1
McMillan, JL; Simons, FE; Simons, KJ1
Woodward, JK1
Kaiser, HB1
Lichtenstein, LM; Massey, WA1
Simons, FE1
Herakleous, M; Kontou-Fili, K; Paleologos, G1
Hägermark, O; Levander, S; Ståhle, M2
Buhner, D; Grant, JA1
Fujiwara, Y; Harada, T; Kashiwabara, K; Nagao, T; Ogawa, T; Otsuki, S1
Simon, RA1
Harvey, RP; Schocket, AL; Wegs, J1
Garafalo, J; Kaplan, AP1
Kaplan, AP1
Fräki, JE; Myöhänen, T; Neittaanmäki, H1
Soter, NA; Wasserman, SI1
Berman, BA; Ross, RN; Sly, RM1
Galant, SP; Klein, GL1
Paterson, S1
Barbanoj, MJ; García-Gea, C; Izquierdo, I; Jané, F; Morte, A; Pérez, I1
Antonijoan, R; Barbanoj, MJ; Donado, E; García-Gea, C; Izquierdo, I; Jané, F; Pérez, I; Solans, A1
Jolles, J; Theunissen, E; van Leeuwen, C; van Oers, A; Vuurman, E1
Kobayashi, K; Omuro, N; Takahara, A1
Bennett, C; Carter, B; Cohen, SN; Sharma, M1
Kannappan, V; Kanthiah, S1

Reviews

9 review(s) available for cyproheptadine and hydroxyzine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The second-generation antihistamines. What makes them different?
    Postgraduate medicine, 1991, May-01, Volume: 89, Issue:6

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyproheptadine; Education, Medical, Continuing; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Loratadine; Terfenadine

1991
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine

1990
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine

1990
Recent advances in H1-receptor antagonist treatment.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Terfenadine; Urticaria

1990
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, Allergic, Seasonal; Triprolidine; Urticaria

1990
Physical urticaria/angioedema: an experimental model of mast cell activation in humans.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:5

    Topics: Angioedema; Body Temperature; Chemotactic Factors; Cyproheptadine; Hot Temperature; Humans; Hydroxyzine; Immunoglobulin E; Light; Mast Cells; Muscle Contraction; Muscle, Smooth, Vascular; Pressure; Urticaria; Vibration

1980
Physical urticaria/angioedema as an experimental model of acute and chronic inflammation in human skin.
    Springer seminars in immunopathology, 1981, Volume: 4, Issue:1

    Topics: Acute Disease; Angioedema; Body Temperature; Chronic Disease; Cold Temperature; Cyproheptadine; Dermatitis; Disease Models, Animal; Hot Temperature; Hydroxyzine; Light; Mast Cells; Pressure; Urticaria; Vibration; Water

1981
H1-antihistamines for chronic spontaneous urticaria.
    The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Controlled Trials as Topic; Urticaria

2014

Trials

19 trial(s) available for cyproheptadine and hydroxyzine

ArticleYear
Suppression of histamine-induced pruritus by three antihistaminic drugs.
    The Journal of allergy and clinical immunology, 1975, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Differential Threshold; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Lactose; Placebos; Pruritus

1975
Treatment of pruritus in allergic dermatoses: an evaluation of the relative efficacy of cyproheptadine and hydroxyzine.
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Dermatitis, Atopic; Dermatitis, Contact; Drug Evaluation; Female; Humans; Hydroxyzine; Male; Middle Aged; Pruritus; Urticaria

1976
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:7

    Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Models, Biological; Single-Blind Method; Skin; Skin Tests; Terfenadine

1992
Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Adult; Automobile Driving; Cetirizine; Cyproheptadine; Double-Blind Method; Electroencephalography; Ethanol; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Psychological Tests; Psychometrics; Psychomotor Performance

1992
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine

1992
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.
    The British journal of dermatology, 1991, Volume: 125, Issue:4

    Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors

1991
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
    Annals of allergy, 1990, Volume: 65, Issue:2

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic

1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria

1990
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine

1990
Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Middle Aged; Random Allocation; Skin

1989
A comparison of antihistaminic and sedative effects of some H1-receptor antagonists.
    Acta dermato-venereologica. Supplementum, 1985, Volume: 114

    Topics: Clemastine; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Psychological Tests; Pyrrolidines

1985
Peripheral antihistamine and central sedative effects of three H1-receptor antagonists.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adult; Central Nervous System; Clemastine; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Neuropsychological Tests; Peripheral Nerves; Pyrrolidines; Skin

1985
A controlled trial of therapy in chronic urticaria.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4

    Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Terbutaline; Urticaria

1981
Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin.
    Journal of the American Academy of Dermatology, 1984, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Cinnarizine; Cold Temperature; Cyproheptadine; Doxepin; Female; Humans; Hydroxyzine; Male; Piperazines; Placebos; Research Design; Urticaria

1984
A comparison of the antipruritic efficacy of hydroxyzine and cyproheptadine in children with atopic dermatitis.
    Annals of allergy, 1980, Volume: 44, Issue:3

    Topics: Adolescent; Antipruritics; Child; Child, Preschool; Cyproheptadine; Dermatitis, Atopic; Dermatologic Agents; Double-Blind Method; Female; Humans; Hydroxyzine; Male; Pruritus

1980
Additive benefits of EFAs in dogs with atopic dermatitis after partial response to antihistamine therapy.
    The Journal of small animal practice, 1995, Volume: 36, Issue:9

    Topics: Animals; Chlorpheniramine; Clemastine; Cyproheptadine; Dermatitis, Atopic; Dog Diseases; Dogs; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Essential; Female; Histamine H1 Antagonists; Hydroxyzine; Male; Severity of Illness Index

1995
Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers.
    Neuropsychobiology, 2004, Volume: 50, Issue:4

    Topics: Adult; Analysis of Variance; Attention; Cross-Over Studies; Cyproheptadine; Decision Making; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Flicker Fusion; Follow-Up Studies; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Motor Activity; Neuropsychological Tests; Pain Measurement; Platelet Activating Factor; Psychomotor Performance; Reaction Time; Self-Assessment; Skin Tests; Statistics, Nonparametric; Time Factors

2004
Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers.
    Human psychopharmacology, 2006, Volume: 21, Issue:1

    Topics: Analysis of Variance; Central Nervous System Depressants; Cetirizine; Cognition; Cross-Over Studies; Cyproheptadine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Interactions; Ethanol; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Psychomotor Performance; Time Factors

2006
Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers.
    Human psychopharmacology, 2007, Volume: 22, Issue:5

    Topics: Adult; Automobile Driving; Cross-Over Studies; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged

2007

Other Studies

19 other study(ies) available for cyproheptadine and hydroxyzine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Tricyclic antidepressants and histamine H1 receptors.
    Mayo Clinic proceedings, 1979, Volume: 54, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic

1979
Relieving localized and generalized pruritus.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Aged; Bandages; Chlorpromazine; Cyproheptadine; Dermatitis; Dermatitis, Seborrheic; Female; Humans; Hydroxyzine; Intertrigo; Lichen Planus; Lidocaine; Middle Aged; Miliaria; Mycoses; Parasitic Diseases; Placebos; Pruritus; Pruritus Ani; Pruritus Vulvae; Psoriasis; Steroids; Trimeprazine; Urticaria

1975
Treatment of autologous immune complex glomerulonephritis with vasoactive amine antagonists.
    The Journal of laboratory and clinical medicine, 1977, Volume: 90, Issue:4

    Topics: Animals; Capillary Permeability; Chlorpheniramine; Cyproheptadine; Disease Models, Animal; Drug Therapy, Combination; Fluorescent Antibody Technique; Glomerulonephritis; Hydroxyzine; Immune Complex Diseases; Immunoglobulin G; Kidney Glomerulus; Male; Methysergide; Rats

1977
Treatment of cold urticaria.
    The British journal of dermatology, 1979, Volume: 101, Issue:1

    Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Diphenhydramine; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Terbutaline; Urticaria

1979
Urticaria and angio-oedema.
    The Medical journal of Australia, 1978, Dec-02, Volume: 2, Issue:6 Suppl

    Topics: Acute Disease; Angioedema; Chronic Disease; Cyproheptadine; Humans; Hydroxyzine; Urticaria

1978
Aquagenic urticaria.
    Cutis, 1992, Volume: 50, Issue:4

    Topics: Child; Combined Modality Therapy; Cyproheptadine; Humans; Hydroxyzine; Male; Parasympathetic Nervous System; Ultraviolet Therapy; Urticaria; Water

1992
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:6 Pt 2

    Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Urticaria

1991
[Non-sedative antihistaminics and binding to central and peripheral H1 histamine receptors].
    Allergie et immunologie, 1991, Volume: 23, Issue:2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cerebellum; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Hydroxyzine; Kinetics; Loratadine; Lung; Organ Specificity; Protein Binding; Receptors, Histamine H1; Terfenadine

1991
Pharmacology of antihistamines.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Time Factors

1990
Serum sickness.
    Dermatologic clinics, 1985, Volume: 3, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Capillary Permeability; Cyproheptadine; Disease Models, Animal; Hepatitis B; Humans; Hydroxyzine; Rabbits; Serum Sickness

1985
Tardive dyskinesia and neurotransmitters: effects of sodium valproate, cyproheptadine, oxypertine, hydroxyzine pamoate and Ca-hopantenate on monoamine metabolites, cyclic nucleotides and gamma-aminobutyric acid in human cerebrospinal fluid.
    Clinical therapeutics, 1984, Volume: 7 Spec No

    Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hydroxyzine; Indoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Piperazines; Valproic Acid

1984
Treatment of systemic mastocytosis.
    The New England journal of medicine, 1980, Jan-24, Volume: 302, Issue:4

    Topics: Cimetidine; Cromolyn Sodium; Cyproheptadine; Drug Therapy, Combination; Guanidines; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Urticaria Pigmentosa

1980
Histamine release and therapy of severe dermatographism.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:2

    Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans; Hydroxyzine; Immunization, Passive; Pruritus; Rats; Urticaria

1981
Exercise-induced hives.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2

    Topics: Cimetidine; Cold Temperature; Cyproheptadine; Histamine; Humans; Hydroxyzine; Hypotension; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Skin Temperature; Tripelennamine; Urticaria

1984
Urticaria.
    Cutis, 1982, Volume: 30, Issue:6

    Topics: Allergens; Cimetidine; Cyproheptadine; Humans; Hydroxyzine; Urticaria

1982
The conventional antihistamine drug cyproheptadine lacks QT-interval-prolonging action in halothane-anesthetized guinea pigs: comparison with hydroxyzine.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:1

    Topics: Action Potentials; Anesthesia; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Halothane; Heart Ventricles; Histamine Antagonists; Hydroxyzine; Injections, Intravenous; Long QT Syndrome

2014
D-Optimal mixture design optimization of an HPLC method for simultaneous determination of commonly used antihistaminic parent molecules and their active metabolites in human serum and urine.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:8

    Topics: Anti-Allergic Agents; Chromatography, High Pressure Liquid; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Limit of Detection; Loratadine; Solid Phase Extraction; Terfenadine

2017