cyproheptadine and desloratadine

cyproheptadine has been researched along with desloratadine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Halstenson, CE; Hilbert, J; Matzke, GR; Opsahl, JA; Perentesis, G; Radwanski, E; Zampaglione, N1
Affrime, MB; Hilbert, J; Perentesis, G; Radwanski, E; Symchowicz, S; Zampaglione, N1
Camelo-Nunes, IC1
Carbó, ML; Izquierdo, I; Merlos, M; Nadal, T; Peña, J; Solans, A1
Antonijoan, R; Barbanoj, M; Carbó, ML; Donado, E; Izquierdo, I; Merlos, M; Nadal, T; Peña, J; Solans, A1
Fan, G; Hong, Z; Wei, H; Wen, J; Wu, Y1
Srinivas, NR1
Bennett, C; Carter, B; Cohen, SN; Sharma, M1
Barkai, L; Izquierdo, I; Maurer, M; Mezei, G; Mitha, E; Potter, P; Santamaría, E1
Antonijoan, R; Campo, C; Coimbra, J; García-Gea, C; Gich, I; Labeaga, L; Puntes, M; Valiente, R1
Bosma, R; Bushby, N; de Esch, IJ; de Graaf, C; Kooistra, AJ; Kuhne, S; Leurs, R; Sheppard, RJ; van den Bor, J; Vischer, HF; Wang, Z; Waring, MJ; Wijtmans, M1
Bolleddula, J; Chowdhury, S; Kato, S; Miyata, Y; Plesescu, M; Shah, A; Zhu, X1

Reviews

3 review(s) available for cyproheptadine and desloratadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New antihistamines: a critical view.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine

2006
H1-antihistamines for chronic spontaneous urticaria.
    The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Controlled Trials as Topic; Urticaria

2014

Trials

4 trial(s) available for cyproheptadine and desloratadine

ArticleYear
Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study.
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cyproheptadine; Female; Food-Drug Interactions; Histamine H1 Antagonists; Humans; Loratadine; Male; Tablets

2007
Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin at steady-state levels: a randomized, open-label, two-way, crossover, Phase I study.
    Clinical therapeutics, 2008, Volume: 30, Issue:9

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Azithromycin; Chromatography, High Pressure Liquid; Confidence Intervals; Cross-Over Studies; Cyproheptadine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Safety; Therapeutic Equivalency

2008
Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2016, Volume: 27, Issue:1

    Topics: Age Factors; Child; Child, Preschool; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Hungary; Loratadine; Male; Quality of Life; Remission Induction; South Africa; Time Factors; Treatment Outcome; Urticaria

2016
Comparative efficacy of bilastine, desloratadine and rupatadine in the suppression of wheal and flare response induced by intradermal histamine in healthy volunteers.
    Current medical research and opinion, 2017, Volume: 33, Issue:1

    Topics: Adult; Benzimidazoles; Cross-Over Studies; Cyproheptadine; Double-Blind Method; Female; Healthy Volunteers; Histamine; Histamine Antagonists; Humans; Injections, Intradermal; Loratadine; Male; Piperidines; Skin

2017

Other Studies

6 other study(ies) available for cyproheptadine and desloratadine

ArticleYear
Pharmacokinetics of loratadine in patients with renal insufficiency.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adult; Cyproheptadine; Female; Humans; Kidney Failure, Chronic; Loratadine; Male; Middle Aged; Piperidines; Pyridines; Renal Dialysis; Time Factors

1990
Excretion of loratadine in human breast milk.
    Journal of clinical pharmacology, 1988, Volume: 28, Issue:3

    Topics: Adult; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Milk, Human; Piperidines; Pyridines

1988
Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers.
    Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2

    Topics: Adult; Asian People; Calibration; Chromatography, Liquid; Cyproheptadine; Drug Stability; Female; Formates; Freezing; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Methanol; Molecular Structure; Platelet Activating Factor; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tandem Mass Spectrometry; Time Factors; Water; Young Adult

2009
Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine.
    Primary care respiratory journal : journal of the General Practice Airways Group, 2009, Volume: 18, Issue:2

    Topics: Cyproheptadine; Cytochrome P-450 CYP3A; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Mutation; Polymorphism, Single Nucleotide

2009
Route to Prolonged Residence Time at the Histamine H
    Journal of medicinal chemistry, 2019, 07-25, Volume: 62, Issue:14

    Topics: Cyproheptadine; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Molecular Docking Simulation; Protein Binding; Receptors, Histamine H1; Time Factors

2019
Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10

    Topics: Animals; Bile; Biotransformation; Carbamates; Cyproheptadine; Drug Evaluation, Preclinical; Hepatobiliary Elimination; Hepatocytes; Humans; Liver; Loratadine; Male; Mianserin; Mice; Transplantation Chimera

2020