cyproheptadine has been researched along with clozapine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 5 (19.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Chiang, GH; Unger, SH | 1 |
| Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP | 1 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA | 1 |
| Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R | 1 |
| McKinnon, RA; Miners, JO; Smith, PA; Sorich, MJ | 1 |
| Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ | 1 |
| Morphy, R; Rankovic, Z | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Richelson, E | 1 |
| Palider, W; Przewlocka, B | 1 |
| Fink, H; Morgenstern, R; Ott, T; Schremmer, C | 1 |
| Spealman, RD | 1 |
| Harrington, A; Kaczmarek, HJ; Steinpreis, RE | 1 |
| Cola, PA; Lee, MA; Mason, EA; Meltzer, HY; Ranjan, R | 1 |
| Brea, J; Cadavid, MI; Caruncho, HJ; Enguix, MJ; Loza, MI; Sánchez, L; Tristán, H; Villazón, M | 1 |
| Cole, JC; Cooper, GD; Goudie, AJ; Sumnall, HR | 1 |
| Crisp, KM; Grupe, RE; Lobsang, TT; Yang, X | 1 |
| Body, S; Bradshaw, CM; Cassaday, HJ; Goudie, AJ; Olarte-Sánchez, CM; Szabadi, E; Valencia Torres, L | 1 |
| Burns, JD; Green, DM; Schembri, F; Stevenson, E | 1 |
3 review(s) available for cyproheptadine and clozapine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Designed multiple ligands. An emerging drug discovery paradigm.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Chemistry, Pharmaceutical; Dopamine D2 Receptor Antagonists; Drug Design; Humans; Ligands; Metabolic Diseases; Peroxisome Proliferator-Activated Receptors; Receptors, Histamine H1; Selective Serotonin Reuptake Inhibitors | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for cyproheptadine and clozapine
| Article | Year |
|---|---|
Relapse following clozapine withdrawal: effect of neuroleptic drugs and cyproheptadine.
Topics: Adult; Antipsychotic Agents; Clozapine; Cyproheptadine; Female; Humans; Male; Perphenazine; Schizophrenia; Serotonin Antagonists; Substance Withdrawal Syndrome | 1996 |
22 other study(ies) available for cyproheptadine and clozapine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1993 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
First pharmacophoric hypothesis for 5-HT7 antagonism.
Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship | 2000 |
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity.
Topics: Catalysis; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Substrate Specificity | 2003 |
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2003 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
The influence of LSD on the hind limb flexor reflex in the spinal rat.
Topics: Animals; Clozapine; Cyproheptadine; Electric Stimulation; Hindlimb; Lysergic Acid Diethylamide; Male; Methyltyrosines; Phenoxybenzamine; Rats; Reflex; Reserpine; Spinal Cord; Time Factors | 1975 |
Atypical neuroleptics suppress dopaminergic behavioral supersensitivity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Clozapine; Cyproheptadine; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Ritanserin; Serotonin Antagonists; Sulpiride; Thioridazine | 1990 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
The effects of cyproheptadine on vacuous jaw movements in rats: a comparison with haloperidol and clozapine.
Topics: Animals; Clozapine; Cyproheptadine; Dose-Response Relationship, Drug; Haloperidol; Jaw; Male; Movement; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Differential regulation of rat peripheral 5-HT(2A) and 5-HT(2B) receptor systems: influence of drug treatment.
Topics: Amphetamines; Animals; Antipsychotic Agents; Aorta, Thoracic; Clozapine; Cyproheptadine; Gastric Fundus; In Vitro Techniques; Ligands; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 2003 |
Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats.
Topics: Animals; Anti-Allergic Agents; Antipsychotic Agents; Clozapine; Conditioning, Operant; Cyproheptadine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Generalization, Psychological; Pharmaceutical Vehicles; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Weight Gain | 2007 |
Biogenic amines modulate pulse rate in the dorsal blood vessel of Lumbriculus variegatus.
Topics: 5-Methoxytryptamine; Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Blood Vessels; Clozapine; Cyproheptadine; Drug Antagonism; Fluoxetine; Heart Rate; Imines; Octopamine; Oligochaeta; Reserpine; Serotonin; Theophylline | 2010 |
A clozapine-like effect of cyproheptadine on progressive ratio schedule performance.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chlordiazepoxide; Clozapine; Conditioning, Operant; Cyproheptadine; Dronabinol; Eating; Female; Haloperidol; Motivation; Performance-Enhancing Substances; Psychomotor Performance; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology | 2012 |
Serotonin syndrome associated with clozapine withdrawal.
Topics: Benzodiazepines; Citalopram; Clozapine; Cyproheptadine; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome; Substance Withdrawal Syndrome | 2013 |