cynarine has been researched along with chlorogenic acid in 29 studies
| Studies (cynarine) | Trials (cynarine) | Recent Studies (post-2010) (cynarine) | Studies (chlorogenic acid) | Trials (chlorogenic acid) | Recent Studies (post-2010) (chlorogenic acid) |
|---|---|---|---|---|---|
| 102 | 1 | 49 | 3,276 | 76 | 2,241 |
| 7 | 1 | 5 | 3,276 | 76 | 2,241 |
| Protein | Taxonomy | cynarine (IC50) | chlorogenic acid (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 7.9 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.95 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 1.05 | |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 0.1 | |
| large T antigen | Betapolyomavirus macacae | 14.67 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 16 (55.17) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Cornell, C; Jia, Q; Kim, TR; King, PJ; Kuan, J; Ma, G; McDougall, BR; Miao, W; Reinecke, MG; Robinson, WE | 1 |
| Berg, T; Seifert, MH; Sperl, B | 1 |
| Cha, JY; Kim, YH; Lee, HY; Lee, YM; Luyen, BT; Tai, BH; Thao, NP | 1 |
| Feng, ZM; Jiang, JS; Yang, PF; Yang, YN; Zhang, PC | 1 |
| Hostomsky, Z; King, PJ; McDougall, B; Reinecke, MG; Robinson, WE; Wu, BW | 1 |
| Adzet, T; Cañigueral, S; Pérez-García, F | 1 |
| Arnason, JT; Baum, BR; Binns, SE; Livesey, JF | 1 |
| Harmia-Pulkkinen, T; Laasonen, M; Vuorela, H; Wennberg, T | 1 |
| Cervellati, R; Govoni, P; Guerra, MC; Guizzardi, S; Renzulli, C; Speroni, E | 1 |
| Benedek, B; Geisz, N; Jäger, W; Kopp, B; Thalhammer, T | 1 |
| Murch, SJ; Peiris, SE; Saxena, PK; Shi, WL; Zobayed, SM | 1 |
| Baricevic, D; Krizman, M; Prosek, M | 1 |
| Ferracane, R; Fogliano, V; Gallo, M; Graziani, G; Ritieni, A | 1 |
| Goodman, BA; Pirker, KF | 1 |
| Crupi, P; De Lisi, A; Grieco, S; Montesano, V; Negro, D; Sarli, G; Sonnante, G | 1 |
| Qin, S; Wen, X | 1 |
| Cardarelli, M; Colla, G; Lucini, L; Rea, E; Rouphael, Y; Svecova, E | 1 |
| Lee, EJ; Leskovar, D; Patil, BS; Yoo, KS | 1 |
| Bulgakov, VP; Chau, LT; Gorpenchenko, TY; Grigorchuk, VP; Koren, OG; Minh, NT; Phan, NH; Rybin, VG; Tchernoded, GK; Veremeichik, GN; Vereshchagina, YV; Zhuravlev, YN | 1 |
| Chen, RD; Dai, JG; Liu, X; Yang, L; Zou, JH | 1 |
| Bonn, GK; Güzel, Y; Huck, CW; Hussain, S; Pezzei, C; Rainer, M | 1 |
| Ehtemam, MH; Rahimmalek, M; Salami, M | 1 |
| Aziz, M; Bnouham, M; Bouanani, NE; Fischmeister, R; Hadda, TB; Hakkou, Z; Leblais, V; Legssyer, A; Maciuk, A; Mekhfi, H; Patel, S; Rauf, A; Shaheen, U; Ziyyat, A | 1 |
| Cui, XH; Liao, DC; Lin, HR; Wang, HB; Yang, ZZ; Yu, YT | 1 |
| Li, R; Pan, S; Tao, M; Wu, T; Xu, T; Xu, X; Zhuo, Z | 1 |
| Cohen, N; Drori, E; Gorelick, J; Kirby, M; Murlanova, K; Pinhasov, A; Pinkus, A; Pletnikov, M; Vinnikova, L | 1 |
| Bayat, Z; Taherkhani, A; Tarokhian, A | 1 |
| Chen, LL; Li, X; Su, ZJ; Wu, JX; Xu, SJ; Yang, L; Zeng, X; Zhou, RL | 1 |
| Dai, GL; Fang, ZY; Ju, WZ; Liu, F; Liu, SJ; Wu, T; Xiong, NN; Zhang, J; Zhao, Y; Zhou, L | 1 |
1 trial(s) available for cynarine and chlorogenic acid
| Article | Year |
|---|---|
Clinical tolerability and pharmacokinetics of Erigerontis hydroxybenzene injection: results of a randomized phase I study in healthy Chinese volunteers.
Topics: Adult; Apigenin; Chlorogenic Acid; Erigeron; Female; Glucuronates; Healthy Volunteers; Humans; Injections, Intravenous; Male; Plant Extracts; Quinic Acid; Young Adult | 2015 |
28 other study(ies) available for cynarine and chlorogenic acid
| Article | Year |
|---|---|
Structure-activity relationships: analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication.
Topics: Anti-HIV Agents; Base Sequence; Caffeic Acids; Cell Line; Cell Survival; Chlorogenic Acid; Cloning, Molecular; DNA Primers; Drug Resistance, Microbial; HIV Integrase Inhibitors; HIV-1; Humans; Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Succinates; Tartrates; Virus Replication | 1999 |
Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains.
Topics: Benzofurans; Biological Products; Caffeic Acids; Drug Discovery; Humans; Lactates; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Models, Molecular; Phenols; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); src Homology Domains; src-Family Kinases | 2009 |
Anti-inflammatory components of Chrysanthemum indicum flowers.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Chrysanthemum; Cyclooxygenase 2; Flavonoids; Flowers; Inflammation; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2015 |
Neuroprotective Caffeoylquinic Acid Derivatives from the Flowers of Chrysanthemum morifolium.
Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Chrysanthemum; Drugs, Chinese Herbal; Flavonoids; Flowers; Glucose; Hydrogen Peroxide; Molecular Structure; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular | 2017 |
Dicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase.
Topics: Acquired Immunodeficiency Syndrome; Caffeic Acids; Chlorogenic Acid; Cinnamates; HIV Envelope Protein gp120; HIV Integrase; HIV Integrase Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Succinates; Tartrates | 1998 |
Activity of artichoke leaf extract on reactive oxygen species in human leukocytes.
Topics: Antioxidants; Asteraceae; Caffeic Acids; Chlorogenic Acid; Cinnamates; Flavonoids; Flow Cytometry; Humans; Hydrogen Peroxide; In Vitro Techniques; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidative Stress; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2000 |
Phytochemical variation in echinacea from roots and flowerheads of wild and cultivated populations.
Topics: Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Echinacea; Ethanol; Phenols; Plant Extracts; Plant Roots; Plant Structures; Species Specificity; Succinates; Tartrates | 2002 |
Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots.
Topics: Asteraceae; Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Echinacea; Fatty Acids, Unsaturated; Glycosides; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Succinates; Tartrates | 2002 |
Efficacy of different Cynara scolymus preparations on liver complaints.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlorogenic Acid; Cinnamates; Cynara scolymus; Lipid Peroxidation; Liver; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2003 |
Choleretic effects of yarrow (Achillea millefolium s.l.) in the isolated perfused rat liver.
Topics: Achillea; Animals; Cholagogues and Choleretics; Cinnamates; Cynara scolymus; In Vitro Techniques; Liver; Luteolin; Male; Perfusion; Plant Extracts; Quinic Acid; Rats; Rats, Sprague-Dawley | 2006 |
Genetic diversity in seed populations of Echinacea purpurea controls the capacity for regeneration, route of morphogenesis and phytochemical composition.
Topics: Caffeic Acids; Chlorogenic Acid; Cinnamates; Echinacea; Free Radical Scavengers; Genetic Variation; Indoleacetic Acids; Indoles; Morphogenesis; Plant Growth Regulators; Plant Roots; Regeneration; Seedlings; Seeds; Succinates | 2006 |
Determination of phenolic compounds in fennel by HPLC and HPLC-MS using a monolithic reversed-phase column.
Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Foeniculum; Phenols; Reproducibility of Results; Rosmarinic Acid; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature | 2007 |
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
Topics: Antioxidants; Arctium; Caffeic Acids; Chlorogenic Acid; Chromatography, Liquid; Cinnamates; Furans; Glucosides; Luteolin; Phenols; Plant Extracts; Plant Leaves; Plant Roots; Quercetin; Quinic Acid; Seeds; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Caffeoylquinic acid derived free radicals identified during antioxidant reactions of bitter tea (Ilex latifolia and Ilex kudincha).
Topics: Antioxidants; Beverages; Chlorogenic Acid; Cinnamates; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Ilex; Oxidation-Reduction; Plant Leaves; Quinic Acid; Superoxides | 2010 |
Polyphenol compounds in artichoke plant tissues and varieties.
Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Cynara scolymus; Glucosides; Luteolin; Mediterranean Region; Plant Extracts; Plant Leaves; Polyphenols; Quinic Acid; Tandem Mass Spectrometry | 2012 |
[Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC].
Topics: Apigenin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Chrysanthemum; Cinnamates; Flowers; Glucosides; Luteolin; Plant Extracts; Quality Control; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Effects of saline stress on mineral composition, phenolic acids and flavonoids in leaves of artichoke and cardoon genotypes grown in floating system.
Topics: Calcium; Calcium, Dietary; Chlorogenic Acid; Cinnamates; Cynara; Flavonoids; Food Quality; Free Radical Scavengers; Hydroponics; Italy; Luteolin; Mediterranean Region; Phenols; Plant Leaves; Polyphenols; Salinity; Sodium Chloride; Species Specificity; Stress, Physiological; Trace Elements | 2013 |
Development of an automated method for Folin-Ciocalteu total phenolic assay in artichoke extracts.
Topics: Antioxidants; Ascorbic Acid; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Cynara scolymus; Food Analysis; Gallic Acid; Phenols; Plant Extracts; Quercetin; Reproducibility of Results; Temperature | 2012 |
The rolC gene increases caffeoylquinic acid production in transformed artichoke cells.
Topics: Cinnamates; Cynara scolymus; Plant Proteins; Quinic Acid | 2014 |
[Regulation of syringin, chlorogenic acid and 1,5-dicaffeoylquinic acid biosynthesis in cell suspension cultures of Saussurea involucrata].
Topics: Cell Culture Techniques; Cells, Cultured; Chlorogenic Acid; Cinnamates; Glucosides; Phenylpropionates; Saussurea | 2014 |
Zirconium silicate assisted removal of residual proteins after organic solvent deproteinization of human plasma, enhancing the stability of the LC-ESI-MS response for the bioanalysis of small molecules.
Topics: Blood Proteins; Chemical Precipitation; Chlorogenic Acid; Chromatography, Liquid; Cinnamates; Humans; Silicates; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Zirconium | 2014 |
Inhibitory effect of different fennel (Foeniculum vulgare) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities.
Topics: Anti-Bacterial Agents; Antioxidants; Apigenin; Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Flavonoids; Foeniculum; Glycation End Products, Advanced; Iran; Microbial Sensitivity Tests; Phenols; Plant Extracts; Quercetin; Rutin; Seeds | 2016 |
Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorogenic Acid; Cinnamates; Hypertension; Inula; Medicine, Traditional; Methanol; NG-Nitroarginine Methyl Ester; Phytochemicals; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Vasodilator Agents | 2017 |
Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans.
Topics: Adipose Tissue; Amyloid beta-Peptides; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chlorogenic Acid; Cinnamates; Cytochromes b; Drugs, Chinese Herbal; Forkhead Transcription Factors; Gene Expression Regulation, Developmental; Heat-Shock Proteins; Longevity; Lonicera; Metallothionein; Paralysis; Quinic Acid; Reactive Oxygen Species; Receptor, Insulin; Stress, Physiological; Superoxide Dismutase; Transcription Factors; Vesicular Transport Proteins | 2018 |
A promising strategy for investigating the anti-aging effect of natural compounds: a case study of caffeoylquinic acids.
Topics: Aging; Animals; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chlorogenic Acid; Cinnamates; Gene Expression Regulation; Insulin; Longevity; Molecular Docking Simulation; Quinic Acid; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Stress, Physiological | 2021 |
Antidepressant-like effects of a chlorogenic acid- and cynarine-enriched fraction from Dittrichia viscosa root extract.
Topics: Animals; Antidepressive Agents; Antioxidants; Asteraceae; Behavior, Animal; Chlorogenic Acid; Cinnamates; Hydrogen Peroxide; Hydroxyindoleacetic Acid; Mice; Paroxetine; Plant Extracts; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry | 2022 |
Cinnamic acids as promising bioactive compounds for cancer therapy by targeting MAPK3: a computational simulation study.
Topics: Caffeic Acids; Chlorogenic Acid; Glucosides; Humans; Neoplasms; Rosmarinic Acid | 2023 |
[Simultaneous determination of 4 phenolic acids in cangerzi by ultra-performance liquid chromatography].
Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Hydroxybenzoates; Plants, Medicinal; Quality Control; Quinic Acid; Reproducibility of Results; Xanthium | 2010 |