Compounds > cyclothiazide

cyclothiazide and s18986-1

cyclothiazide has been researched along with s18986-1 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caignard, DH; Danober, L; Dintilhac, G; Fraikin, P; Francotte, P; Goffin, E; Graindorge, E; Lestage, P; Pirotte, B; Thomas, JY; Tullio, Pd1
Caignard, DH; Danober, L; de Tullio, P; Diouf, O; Fraikin, P; Francotte, P; Lestage, P; Pirotte, B; Podona, T; Thomas, JY1
Caignard, DH; Chiap, P; Danober, L; de Tullio, P; Fraikin, P; Francotte, P; Gillotin, F; Goffin, E; Lestage, P; Pirotte, B; Thomas, JY; Van Heugen, JC1
Closier, M; Iop, F; Lestage, P; Lockhart, B1

Other Studies

4 other study(ies) available for cyclothiazide and s18986-1

ArticleYear
Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors.
    Journal of medicinal chemistry, 2007, Jun-28, Volume: 50, Issue:13

    Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cognition; Cyclic S-Oxides; Drug Design; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Norepinephrine; Oocytes; Rats; Rats, Wistar; Receptors, AMPA; Recognition, Psychology; RNA, Messenger; Structure-Activity Relationship; Thiadiazines; Xenopus

2007
Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators.
    Bioorganic & medicinal chemistry, 2008, Dec-01, Volume: 16, Issue:23

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diazoxide; Oocytes; Rats; Rats, Wistar; Receptors, AMPA; Solubility; Structure-Activity Relationship; Thiadiazines; Xenopus laevis

2008
New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors.
    Journal of medicinal chemistry, 2010, Feb-25, Volume: 53, Issue:4

    Topics: Administration, Oral; Allosteric Regulation; Animals; Benzothiadiazines; Cells, Cultured; Cyclic S-Oxides; Excitatory Amino Acid Agents; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Male; Microsomes, Liver; Neurons; Nootropic Agents; Oocytes; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Recognition, Psychology; Structure-Activity Relationship; Xenopus laevis

2010
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium

2000