cyclothiazide has been researched along with glutamic acid in 106 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 42 (39.62) | 18.2507 |
| 2000's | 53 (50.00) | 29.6817 |
| 2010's | 11 (10.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butini, S; Campiani, G; Christensen, JK; Coccone, SS; De Angelis, M; Fiorini, I; Gemma, S; Guarino, E; Morelli, E; Novellino, E; Pickering, DS; Schousboe, A; Trotta, F | 1 |
| England, PM; Fleming, JJ | 1 |
| Barnes, JM; Dev, KK; Henley, JM | 1 |
| Fattman, CL; Hoyt, KR; Rajdev, S; Reynolds, IJ | 1 |
| Geiger, JR; Jonas, P; Koh, DS; Sakmann, B | 1 |
| Camici, O; Corazzi, L; Fallarino, F; Fioretti, MC; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Silla, S | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Bowie, D; Mayer, ML; Partin, KM | 1 |
| Mennerick, S; Zorumski, CF | 1 |
| Moudy, AM; Rothman, SM; Yamada, KA | 1 |
| Costa, E; Livsey, CT; Vicini, S | 1 |
| Raman, IM; Trussell, LO; Zhang, S | 1 |
| Baraldi, M; Bertolino, M; Braghiroli, D; Costa, E; DiBella, M; Parenti, C; Vicini, S | 1 |
| Hablitz, JJ; Pelletier, MR | 1 |
| Gallo, V; Holtzclaw, LA; Russell, JT | 1 |
| Huganir, RL; Moshaver, A; Raymond, LA; Tingley, WG | 1 |
| Arai, A; Lynch, G | 2 |
| Bähring, R; Fleck, MW; Mayer, ML; Patneau, DK | 1 |
| Mennerick, S; Que, J; Zorumski, CF | 1 |
| Bacskai, B; Pleasure, D; Yoshioka, A | 1 |
| Gershon, MD; Kirchgessner, AL; Liu, MT; Rothstein, JD | 1 |
| Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Croucher, MJ; Patel, DR | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Kinney, GA; Overstreet, LS; Slater, NT | 1 |
| Dougherty, PM; Lenz, FA; Mittman, S | 1 |
| Gao, F; Maguire, G; Maple, B; Wu, SM; Yang, JH | 1 |
| Horiuchi, K; Itoh, A; Itoh, T; Pleasure, D | 1 |
| Yamada, KA | 1 |
| Covey, DF; Hill, MW; Hu, Y; Yamada, KA | 1 |
| Badre, SE; Morsette, DJ; Sidorowicz, HE; Sladek, CD | 1 |
| Maguire, G | 1 |
| Shen, Y; Yang, XL | 1 |
| Akaike, N; Harata, N; Katayama, J | 1 |
| Blank, T; Cepok, S; Grafelmann, B; Kügler, H; Nijholt, I; Spiess, J | 1 |
| Hjelmstad, GO; Isaac, JT; Malenka, RC; Nicoll, RA | 1 |
| Dzubay, JA; Jahr, CE | 1 |
| Beart, PM; Cheung, NS; Giardina, SF; John, CA; Pascoe, CJ | 1 |
| Kawai, F | 1 |
| Benz, A; Isenberg, KE; Krause, JE; Mennerick, S; Shen, W; Shimamoto, K; Tanaka, K; Xu, W; Zorumski, CF | 1 |
| Shen, Y; Yang, XL; Zhou, Y | 1 |
| Gao, F; Maple, BR; Wu, SM | 1 |
| Hollmann, M; Morth, T; Strutz, N; Thalhammer, A | 1 |
| Akaike, N; Nabekura, J; Nakanishi, H; Noda, M | 1 |
| Cooke, IM; Duan, S | 1 |
| Trussell, LO; Turecek, R | 1 |
| Isaac, JT; Kidd, FL | 1 |
| Kijima, H; Koike, M; Ozawa, S; Tsukada, S; Tsuzuki, K | 1 |
| Kohda, K; Wang, Y; Yuzaki, M | 1 |
| Choi, S; Klingauf, J; Tsien, RW | 1 |
| Durkin, JP; Gendron, TF; MacLean, S; Mealing, G; Morley, P; Small, DL; Tremblay, R | 1 |
| Cherubini, E; Gasparini, S; Saviane, C; Voronin, LL | 1 |
| Haas, HL; Sergeeva, OA; Sharonova, IN; Vorobjev, VS | 1 |
| Bolshakov, KV; Buldakova, SL; Magazanik, LG; Tikhonov, DB | 1 |
| Brorson, JR; Ihle, EC; Patneau, DK; Robberecht, W; Vandenberghe, W | 1 |
| Chatton, JY; Magistretti, PJ; Marquet, P | 1 |
| Croucher, MJ; Patel, DR; Young, AM | 1 |
| Madison, DV; Montgomery, JM; Pavlidis, P | 1 |
| Lei, S; MacDonald, JF; Orser, BA; Reynolds, JN; Thatcher, GR | 1 |
| Vignes, M | 1 |
| Gardner, SM; Oertel, D; Trussell, LO | 1 |
| Hasegawa, J; Matsui, K; Tachibana, M | 1 |
| Linden, DJ | 1 |
| Grimaldi, M; Hampson, AJ | 1 |
| Howe, JR; Robert, A; Usowicz, MM; Wall, MJ | 1 |
| Cull-Candy, SG; Liu, SJ | 1 |
| Heggelund, P; Kielland, A | 1 |
| Regehr, WG; Xu-Friedman, MA | 1 |
| Clark, S; Leever, JD; Partin, KM; Weeks, AM | 1 |
| Chen, G; Deng, L | 1 |
| Jahr, CE; Matsui, K | 1 |
| Arai, AC; Suzuki, E; Xia, YF | 1 |
| Lisman, JE; Raghavachari, S | 1 |
| Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T | 1 |
| Koike-Tani, M; Saitoh, N; Takahashi, T | 1 |
| Magistretti, PJ; Pellerin, L | 1 |
| Cheng, Y; Nakagawa, T; Ramm, E; Sheng, M; Walz, T | 1 |
| Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL | 1 |
| Bollmann, JH; Sakmann, B | 1 |
| Arai, AC; Kessler, M; Suzuki, E | 1 |
| Korogod, N; Lou, X; Schneggenburger, R | 1 |
| Barsoumian, EL; Carvalho, AL; Carvalho, AP; Duarte, CB; Ham, J; Iizuka, M; Lopes, MC; Santos, AE | 1 |
| Clements, JM; Vanhoose, AM; Winder, DG | 1 |
| Bräuner-Osborne, H; Jensen, AA; Strange, M | 1 |
| Iino, M; Ozawa, S; Shimamoto, K; Takayasu, Y; Tanaka, K | 1 |
| Kardos, J; Lasztóczi, B | 1 |
| Bernareggi, A; Dueñas, Z; Miledi, R; Reyes-Ruiz, JM; Ruzzier, F | 1 |
| Ali, DW; Patten, SA | 1 |
| Baba, A; Chen, H; Jones, M; Kiedrowski, L; Kintner, DB; Matsuda, T; Sun, D | 1 |
| Chen, JH; Nie, H; Pan, ZZ; Weng, HR | 1 |
| Fuda, H; Hanyu, O; Kohjitani, A; Strott, CA | 1 |
| Chittajallu, R; Gallo, V; Kunze, A; Mangin, JM | 1 |
| Neher, E; Taschenberger, H; Wang, LY | 1 |
| Eguchi, K; Kanda, T; Takahashi, T; Yamashita, T | 1 |
| Ahring, PK; Gajhede, M; Hald, H; Kastrup, JS; Liljefors, T; Timmermann, DB | 1 |
| Prieto, ML; Wollmuth, LP | 1 |
| Gong, HQ; Liang, PJ; Sun, Y; Zhang, YT | 1 |
| Burdakov, D; Fugger, L; Jensen, LT; Karnani, MM; Venner, A | 1 |
| Baranovic, J; Kasai, N; Madden, DR; Midgett, CR; Ramanujan, CS; Ryan, JF; Torimitsu, K | 1 |
| Blachowicz, L; Ghisi, V; Lau, AY; Plested, AJ; Roux, B; Salazar, H | 1 |
| Cho, S; Diamond, JS; Graydon, CW; Grimes, WN; Kachar, B; von Gersdorff, H | 1 |
| Christiansen, GB; Egebjerg, J; Frydenvang, K; Gouliaev, AH; Harbak, B; Hede, SE; Holm, MM; Kastrup, JS; Olsen, L | 1 |
| Aslam, M; Farrow, P; Khodosevich, K; Monyer, H; Sapir, Y; Schulmann, A; Stern-Bach, Y; von Engelhardt, J | 1 |
| Barygin, OI | 1 |
| Li, YX; Lippa, A; Purcell, R; Radin, DP; Rogers, G | 1 |
106 other study(ies) available for cyclothiazide and glutamic acid
| Article | Year |
|---|---|
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.
Topics: Animals; Cell Line; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Humans; Ligands; Molecular Structure; Oocytes; Pyrimidinones; Rats; Receptors, Glutamate; Spodoptera; Structure-Activity Relationship; Thiophenes; Xenopus laevis | 2008 |
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA | 2010 |
Cyclothiazide unmasks AMPA-evoked stimulation of [3H]-L-glutamate release from rat hippocampal synaptosomes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Carbachol; Diuretics; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Potassium; Presynaptic Terminals; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical; Synaptosomes | 1994 |
Cyclothiazide modulates AMPA receptor-mediated increases in intracellular free Ca2+ and Mg2+ in cultured neurons from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Drug Synergism; Glutamic Acid; Kainic Acid; Magnesium; Neurons; Prosencephalon; Rats; Receptors, AMPA | 1995 |
Ca(2+)-permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium Channels; Dendrites; Diuretics; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Chloride Symporter Inhibitors | 1995 |
[3H]aniracetam binds to specific recognition sites in brain membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Brain; Cells, Cultured; Cerebellum; Glutamic Acid; Male; Membranes; Phorbol 12,13-Dibutyrate; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tritium | 1995 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Structural determinants of allosteric regulation in alternatively spliced AMPA receptors.
Topics: Allosteric Regulation; Alternative Splicing; Amino Acid Sequence; Animals; Benzothiadiazines; Embryo, Mammalian; Embryo, Nonmammalian; Glutamic Acid; Glutamine; Humans; Kainic Acid; Kidney; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Receptors, AMPA; Receptors, Kainic Acid; Serine; Transfection; Xenopus laevis | 1995 |
Presynaptic influence on the time course of fast excitatory synaptic currents in cultured hippocampal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Magnesium; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1995 |
Rapid desensitization determines the pharmacology of glutamate neurotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Calcium; Cells, Cultured; Diuretics; Dizocilpine Maleate; Electrophysiology; Fura-2; Glutamic Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors | 1994 |
Glutamate-activated currents in outside-out patches from spiny versus aspiny hilar neurons of rat hippocampal slices.
Topics: Action Potentials; Animals; Benzothiadiazines; Glutamates; Glutamic Acid; Hippocampus; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses | 1993 |
Pathway-specific variants of AMPA receptors and their contribution to neuronal signaling.
Topics: Animals; Benzothiadiazines; Brain Stem; Chick Embryo; Cochlear Nucleus; Electrophysiology; Glutamates; Glutamic Acid; Hearing; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Neurons; Receptors, AMPA; Signal Transduction; Synapses | 1994 |
Modulation of AMPA/kainate receptors by analogues of diazoxide and cyclothiazide in thin slices of rat hippocampus.
Topics: Action Potentials; Animals; Benzothiadiazines; Diazoxide; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Molecular Structure; Rats; Receptors, AMPA; Receptors, Kainic Acid | 1993 |
Altered desensitization produces enhancement of EPSPs in neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzothiadiazines; Cerebral Cortex; Culture Techniques; Female; Glutamic Acid; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
AMPA receptors shape Ca2+ responses in cortical oligodendrocyte progenitors and CG-4 cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Oligodendroglia; Quinoxalines; Receptors, AMPA; Time Factors | 1995 |
Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Benzothiadiazines; Cell Line; Cell Survival; Concanavalin A; Dizocilpine Maleate; DNA Primers; Evoked Potentials; Glutamic Acid; Humans; Ion Channels; Kainic Acid; Kidney; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Transfection | 1996 |
Response to repetitive stimulation of AMPA receptors in patches excised from fields CA1 and CA3 of the hippocampus.
Topics: Animals; Benzothiadiazines; Diuretics; Electric Stimulation; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1996 |
AMPA receptor heterogeneity in rat hippocampal neurons revealed by differential sensitivity to cyclothiazide.
Topics: Animals; Benzothiadiazines; Cells, Cultured; Diuretics; Glutamic Acid; Hippocampus; Neurons; Perfusion; Plasmids; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; Sodium Chloride Symporter Inhibitors | 1996 |
Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Benzothiadiazines; Calcium; Cells, Cultured; Cycloleucine; Evoked Potentials; Glutamic Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Virulence Factors, Bordetella; Wheat Germ Agglutinins | 1996 |
Pathophysiology of oligodendroglial excitotoxicity.
Topics: Acetylcysteine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aurintricarboxylic Acid; Benzothiadiazines; Biological Transport; Calcium; Cell Line; Cell Membrane; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Nerve Tissue Proteins; Oligodendroglia; Rats; Receptors, AMPA; RNA, Messenger | 1996 |
Glutamatergic enteric neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Benzothiadiazines; Calcium; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hexamethonium; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Muscle, Smooth; Myenteric Plexus; Neurons; Nicotine; Organelles; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin | 1997 |
Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cerebral Cortex; Choline; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Norepinephrine; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Serotonin; Synaptosomes | 1997 |
Evidence for a role of presynaptic AMPA receptors in the control of neuronal glutamate release in the rat forebrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Benzothiadiazines; Binding, Competitive; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neurons; Presynaptic Terminals; Prosencephalon; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Prolonged physiological entrapment of glutamate in the synaptic cleft of cerebellar unipolar brush cells.
Topics: Animals; Benzothiadiazines; Cell Polarity; Cerebellum; Diuretics; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Chloride Symporter Inhibitors; Synapses; Vestibular Nuclei | 1997 |
Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Macaca fascicularis; Male; N-Methylaspartate; Thalamic Nuclei | 1998 |
Postsynaptic responses of horizontal cells in the tiger salamander retina are mediated by AMPA-preferring receptors.
Topics: Ambystoma; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Concanavalin A; Dark Adaptation; Electrophysiology; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Receptors, AMPA; Synapses | 1998 |
AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Channel Blockers; Cell Death; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Homeostasis; Humans; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Nimodipine; Potassium; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Spider Venoms | 1998 |
AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices.
Topics: Animals; Benzothiadiazines; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 1998 |
AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons.
Topics: Animals; Benzothiadiazines; Cell Survival; Cells, Cultured; Dioxoles; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neurons; Neurotoxins; Piperidines; Quinoxalines; Rats; Receptors, AMPA | 1998 |
The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Receptors, GABA; Synapses; Synaptic Transmission | 1998 |
Role of non-NMDA receptors in osmotic and glutamate stimulation of vasopressin release: effect of rapid receptor desensitization.
Topics: Animals; Benzothiadiazines; Concanavalin A; Down-Regulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypothalamo-Hypophyseal System; In Vitro Techniques; Magnesium; Male; Osmolar Concentration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sodium Chloride; Vasopressins | 1998 |
Rapid desensitization converts prolonged glutamate release into a transient EPSC at ribbon synapses between retinal bipolar and amacrine cells.
Topics: Action Potentials; Ambystoma; Animals; Antihypertensive Agents; Benzothiadiazines; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channel Gating; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Presynaptic Terminals; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Retina; Synaptic Transmission | 1999 |
Zinc modulation of AMPA receptors may be relevant to splice variants in carp retina.
Topics: Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzothiadiazines; Drug Synergism; Glutamic Acid; Goldfish; Membrane Potentials; Patch-Clamp Techniques; Receptors, AMPA; Retina; Zinc | 1999 |
Excitatory amino acid responses in relay neurons of the rat lateral geniculate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Geniculate Bodies; Glutamic Acid; Glycine; Ionophores; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Nystatin; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
NS-257, a novel competitive AMPA receptor antagonist, interacts with kainate and NMDA receptors.
Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Indoles; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Microinjections; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; RNA, Messenger; Sulfonamides; Xenopus | 1999 |
Lack of AMPA receptor desensitization during basal synaptic transmission in the hippocampal slice.
Topics: Animals; Benzothiadiazines; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Microelectrodes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission | 1999 |
The concentration of synaptically released glutamate outside of the climbing fiber-Purkinje cell synaptic cleft.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Benzothiadiazines; Cell Membrane; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Kinetics; Models, Biological; Neuroglia; Patch-Clamp Techniques; Probability; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Synapses; Temperature | 1999 |
Cyclothiazide and GYKI 52466 modulate AMPA receptor-mediated apoptosis in cortical neuronal cultures.
Topics: Animals; Anti-Anxiety Agents; Apoptosis; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Glutamic Acid; Mice; Neocortex; Neurons; Neuroprotective Agents; Receptors, AMPA | 1999 |
Characterization of spontaneous excitatory synaptic currents in newt retinal bipolar cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Computer Simulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Models, Neurological; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Salamandridae; Synaptic Transmission | 1999 |
Substrate turnover by transporters curtails synaptic glutamate transients.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzothiadiazines; Cells, Cultured; Evoked Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Oocytes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Xenopus laevis | 1999 |
Characterization of AMPA receptors on isolated amacrine-like cells in carp retina.
Topics: Alternative Splicing; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cell Separation; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Phenoxyacetates; Receptors, AMPA; Retina | 1999 |
Glutamate receptors differ in rod- and cone-dominated off-center bipolar cells.
Topics: Ambystoma; Animals; Axons; Benzothiadiazines; Cell Size; Dendrites; Down-Regulation; Electric Conductivity; Evoked Potentials, Visual; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Larva; Photic Stimulation; Receptors, AMPA; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Synapses; Visual Pathways | 1999 |
A desensitization-inhibiting mutation in the glutamate binding site of rat alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is dominant in heteromultimeric complexes.
Topics: Amino Acid Sequence; Animals; Benzothiadiazines; Binding Sites; Female; Genes, Dominant; Glutamic Acid; Mutation; Oocytes; Protein Isoforms; Rats; Receptors, AMPA; RNA Editing; Xenopus laevis | 1999 |
AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Concanavalin A; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Microglia; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 2000 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Regulation of kinetic properties of GluR2 AMPA receptor channels by alternative splicing.
Topics: Alternative Splicing; Animals; Antihypertensive Agents; Benzothiadiazines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Mutagenesis; Oocytes; Patch-Clamp Techniques; Rats; Receptors, AMPA; Xenopus | 2000 |
Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Conserved Sequence; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Kainic Acid; Kidney; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Mutagenesis; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Receptors, Glutamate; Transfection | 2000 |
Postfusional regulation of cleft glutamate concentration during LTP at 'silent synapses'.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antihypertensive Agents; Benzothiadiazines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glutamic Acid; Long-Term Potentiation; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2000 |
Pharmacological and molecular characterization of glutamate receptors in the MIN6 pancreatic beta-cell line.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Biological Transport; Calcium; Cell Survival; DNA Primers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Islets of Langerhans; Kainic Acid; Protein Kinase C; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms; Tumor Cells, Cultured | 2000 |
Silent synapses in the developing hippocampus: lack of functional AMPA receptors or low probability of glutamate release?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzothiadiazines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Mossy Fibers, Hippocampal; Piperazines; Probability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Temperature | 2000 |
Differential modulation of AMPA receptors by cyclothiazide in two types of striatal neurons.
Topics: Alternative Splicing; Animals; Antihypertensive Agents; Benzothiadiazines; Cell Separation; Cell Size; Corpus Striatum; DNA Primers; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
Ca2+-dependent desensitization of AMPA receptors.
Topics: Adamantane; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Kainic Acid; Neurons; Nootropic Agents; Pyrrolidinones; Rats; Receptors, AMPA | 2000 |
AMPA receptor current density, not desensitization, predicts selective motoneuron vulnerability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Posterior Horn Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium | 2001 |
Pair recordings reveal all-silent synaptic connections and the postsynaptic expression of long-term potentiation.
Topics: Animals; Benzothiadiazines; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Positive allosteric modulators of AMPA receptors reduce proton-induced receptor desensitization in rat hippocampal neurons.
Topics: Allosteric Regulation; Animals; Benzothiadiazines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Ion Channel Gating; Nerve Tissue Proteins; Neurons; Nitrates; Patch-Clamp Techniques; Protons; Pyrrolidinones; Rats; Rats, Wistar; Receptors, AMPA; Wheat Germ Agglutinins | 2001 |
Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons.
Topics: Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA; Receptors, Kainic Acid; Synaptic Transmission; Tetrodotoxin | 2001 |
Correlation of AMPA receptor subunit composition with synaptic input in the mammalian cochlear nuclei.
Topics: Alternative Splicing; Animals; Auditory Pathways; Benzothiadiazines; Cochlear Nerve; Cochlear Nucleus; Diuretics; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kinetics; Mice; Mice, Inbred ICR; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Isoforms; Protein Subunits; Receptors, AMPA; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical; Sucrose; Synaptic Transmission | 2001 |
Modulation of excitatory synaptic transmission by GABA(C) receptor-mediated feedback in the mouse inner retina.
Topics: Amacrine Cells; Animals; Benzothiadiazines; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Light; Mice; Mice, Inbred C57BL; Phosphinic Acids; Pyridines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Cone Photoreceptor Cells; Synaptic Transmission | 2001 |
The expression of cerebellar LTD in culture is not associated with changes in AMPA-receptor kinetics, agonist affinity, or unitary conductance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Mice; Phorbol Esters; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
12-hydroxyeicosatetrenoate (12-HETE) attenuates AMPA receptor-mediated neurotoxicity: evidence for a G-protein-coupled HETE receptor.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Benzothiadiazines; Calcium Channels; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); L-Lactate Dehydrogenase; Models, Biological; Neurons; Neuroprotective Agents; Pertussis Toxin; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Eicosanoid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 2002 |
The speeding of EPSC kinetics during maturation of a central synapse.
Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cell Differentiation; Cells, Cultured; Cerebellum; Dicarboxylic Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Male; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Synaptic Transmission; Synaptic Vesicles | 2002 |
Activity-dependent change in AMPA receptor properties in cerebellar stellate cells.
Topics: Action Potentials; Animals; Benzothiadiazines; Calcium; Cerebellum; Diuretics; Electric Stimulation; Electrophysiology; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Permeability; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Chloride Symporter Inhibitors; Spermine; Synapses; Tetrodotoxin | 2002 |
AMPA and NMDA currents show different short-term depression in the dorsal lateral geniculate nucleus of the rat.
Topics: Animals; Benzothiadiazines; Cerebral Cortex; Electric Stimulation; Excitatory Postsynaptic Potentials; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Kinetics; Magnesium; Neurons, Afferent; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Retina; Synapses; Thalamus | 2002 |
Ultrastructural contributions to desensitization at cerebellar mossy fiber to granule cell synapses.
Topics: Animals; Benzothiadiazines; Binding Sites; Cerebellum; Computer Simulation; Diffusion; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Imaging, Three-Dimensional; In Vitro Techniques; Microscopy, Electron; Models, Neurological; Nerve Fibers; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 2003 |
Identification of a site in GluR1 and GluR2 that is important for modulation of deactivation and desensitization.
Topics: Amino Acid Substitution; Animals; Benzothiadiazines; Binding Sites; Dioxoles; Glutamic Acid; Kinetics; Models, Molecular; Oocytes; Piperidines; Point Mutation; Receptors, AMPA; Serine; Threonine; Transfection; Xenopus laevis | 2003 |
Cyclothiazide potently inhibits gamma-aminobutyric acid type A receptors in addition to enhancing glutamate responses.
Topics: Animals; Benzothiadiazines; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses | 2003 |
Ectopic release of synaptic vesicles.
Topics: Animals; Animals, Newborn; Benzothiadiazines; Cerebellum; Exocytosis; Glutamic Acid; In Vitro Techniques; Rats; Receptors, AMPA; Synaptic Vesicles | 2003 |
Modulation of AMPA receptor kinetics differentially influences synaptic plasticity in the hippocampus.
Topics: Animals; Animals, Newborn; Benzothiadiazines; Cell Line; Central Nervous System Stimulants; Dioxoles; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Embryo, Mammalian; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Kidney; Long-Term Potentiation; Neuronal Plasticity; Patch-Clamp Techniques; Picrotoxin; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses; Time Factors; Transfection | 2004 |
Properties of quantal transmission at CA1 synapses.
Topics: Benzothiadiazines; Computer Simulation; Diuretics; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Kinetics; Monte Carlo Method; Neural Networks, Computer; Receptors, AMPA; Stochastic Processes; Synapses; Synaptic Transmission | 2004 |
Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons.
Topics: Animals; Benzothiadiazines; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Concanavalin A; Cysteine Proteinase Inhibitors; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Nerve Tissue Proteins; Neurons; Nifedipine; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors | 2004 |
Mechanisms underlying developmental speeding in AMPA-EPSC decay time at the calyx of Held.
Topics: Animals; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Glutamic Acid; In Vitro Techniques; Kinetics; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Time Factors | 2005 |
Ampakine CX546 bolsters energetic response of astrocytes: a novel target for cognitive-enhancing drugs acting as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzothiadiazines; Cell Separation; Cells, Cultured; Cerebellum; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; Lactic Acid; Mice; Nootropic Agents; Piperidines; Receptors, AMPA | 2005 |
Structure and different conformational states of native AMPA receptor complexes.
Topics: Animals; Benzothiadiazines; Brain; Cell Membrane; Glutamic Acid; Ligands; Models, Molecular; Multiprotein Complexes; Protein Structure, Quaternary; Protein Structure, Tertiary; Rats; Receptors, AMPA | 2005 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Control of synaptic strength and timing by the release-site Ca2+ signal.
Topics: Acetates; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain Stem; Calcium; Calcium Chloride; Calcium Signaling; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Ethylenediamines; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kinetics; Lasers; Models, Neurological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Photolysis; Predictive Value of Tests; Presynaptic Terminals; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 2005 |
C-terminal truncation affects kinetic properties of GluR1 receptors.
Topics: Amino Acid Sequence; Benzodiazepines; Benzothiadiazines; Cell Line; Diuretics; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kidney; Kinetics; Ligands; Molecular Sequence Data; Mutagenesis; Protein Binding; Protein Structure, Tertiary; Receptors, AMPA; Structure-Activity Relationship | 2005 |
Presynaptic Ca2+ requirements and developmental regulation of posttetanic potentiation at the calyx of Held.
Topics: Age Factors; Aniline Compounds; Animals; Animals, Newborn; Benzothiadiazines; Brain Stem; Calcium; Diagnostic Imaging; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Neuronal Plasticity; Neurons; Oxazoles; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Synapses; Synaptic Transmission; Time Factors | 2005 |
Excitotoxicity mediated by Ca2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Benzothiadiazines; Calcium; Cell Line; Cell Survival; DNA; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Humans; Protein Subunits; Receptors, AMPA; Signal Transduction; Time Factors; Transcription Factor AP-1 | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Functional characterisation of homomeric ionotropic glutamate receptors GluR1-GluR6 in a fluorescence-based high throughput screening assay.
Topics: Aniline Compounds; Benzothiadiazines; Calcium; Cell Line; Combinatorial Chemistry Techniques; Concanavalin A; Drug Evaluation, Preclinical; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescence; Glutamic Acid; Humans; Kainic Acid; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Signal Transduction; Xanthenes | 2006 |
Glial glutamate transporters maintain one-to-one relationship at the climbing fiber-Purkinje cell synapse by preventing glutamate spillover.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzothiadiazines; Cerebellum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Methacrylates; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers; Neural Inhibition; Phosphorylcholine; Purkinje Cells; Synapses | 2006 |
Cyclothiazide prolongs low [Mg2+]-induced seizure-like events.
Topics: 4-Aminopyridine; Animals; Benzodiazepines; Benzothiadiazines; Diuretics; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Magnesium Deficiency; Male; Potassium Channel Blockers; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Presynaptic; Seizures | 2006 |
Properties of glutamate receptors of Alzheimer's disease brain transplanted to frog oocytes.
Topics: Alzheimer Disease; Animals; Anura; Benzothiadiazines; Blotting, Western; Brain Tissue Transplantation; Cell Membrane; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Humans; Kainic Acid; Oocytes; Protein Subunits; Receptors, GABA; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2007 |
AMPA receptors associated with zebrafish Mauthner cells switch subunits during development.
Topics: Animals; Benzothiadiazines; Excitatory Postsynaptic Potentials; Glutamic Acid; Ion Channel Gating; Kinetics; Neurons; Protein Subunits; Receptors, AMPA; Rhombencephalon; Synaptic Transmission; Zebrafish; Zebrafish Proteins | 2007 |
AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Cell Death; Cells, Cultured; Central Nervous System; Excitatory Amino Acid Agonists; Glutamic Acid; Membrane Transport Proteins; Mitochondria; Neurotoxins; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2007 |
Glial glutamate transporter 1 regulates the spatial and temporal coding of glutamatergic synaptic transmission in spinal lamina II neurons.
Topics: Animals; Benzothiadiazines; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 2007 |
Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: relevance of AMPA receptor-mediated NO signaling.
Topics: Animals; Benzothiadiazines; Cell Line, Tumor; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Isoenzymes; Neuroglia; Nitric Oxide; Pregnenolone; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfotransferases | 2008 |
Satellite NG2 progenitor cells share common glutamatergic inputs with associated interneurons in the mouse dentate gyrus.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Animals, Newborn; Antigens; Benzothiadiazines; Cyclopropanes; Dentate Gyrus; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Glycine; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Transgenic; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Phosphoric Diester Hydrolases; Picrotoxin; Proteoglycans; Satellite Cells, Perineuronal; Sodium Channel Blockers; Stem Cells; Tetrodotoxin | 2008 |
Synaptic vesicles in mature calyx of Held synapses sense higher nanodomain calcium concentrations during action potential-evoked glutamate release.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Benzothiadiazines; Brain Stem; Calcium; Electric Stimulation; Excitatory Postsynaptic Potentials; Galactolipids; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Models, Biological; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Statistics, Nonparametric; Synapses; Synaptic Vesicles; Time Factors | 2008 |
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Vesicles; Temperature; Tetrodotoxin | 2009 |
Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
Topics: Allosteric Regulation; Animals; Antihypertensive Agents; Benzothiadiazines; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Dimerization; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Molecular Structure; Patch-Clamp Techniques; Piperazine; Piperazines; Protein Structure, Quaternary; Rats; Receptors, AMPA | 2009 |
Gating modes in AMPA receptors.
Topics: Antihypertensive Agents; Benzothiadiazines; Biophysics; Cell Line, Transformed; Electric Stimulation; Glutamic Acid; Green Fluorescent Proteins; Humans; Ion Channel Gating; Membrane Potentials; Patch-Clamp Techniques; Probability; Receptors, AMPA; Transfection | 2010 |
The mechanisms of Zn2+ effects on Ca2+-permeable AMPA receptors on carp retinal horizontal cells.
Topics: Animals; Benzothiadiazines; Calcium; Carps; Cells, Cultured; Extracellular Space; GABA Modulators; Glutamic Acid; Isotonic Solutions; Kainic Acid; Membrane Potentials; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Receptors, AMPA; Retinal Horizontal Cells; Ringer's Solution; Zinc | 2010 |
Direct and indirect control of orexin/hypocretin neurons by glycine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Alanine; Animals; Animals, Newborn; Benzothiadiazines; Chloride Channels; Electrophysiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hypothalamus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, Glutamate; Receptors, Glycine; Strychnine; Synaptic Potentials | 2011 |
Reconstitution of homomeric GluA2(flop) receptors in supported lipid membranes: functional and structural properties.
Topics: Animals; Benzothiadiazines; Glutamic Acid; Ion Channel Gating; Lipid Bilayers; Lipids; Liposomes; Membrane Potentials; Microscopy, Atomic Force; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA | 2013 |
A conformational intermediate in glutamate receptor activation.
Topics: Benzothiadiazines; Biophysical Phenomena; Cell Line, Transformed; Crystallography, X-Ray; Cysteine; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Membrane Potentials; Models, Molecular; Molecular Conformation; Mutation; Patch-Clamp Techniques; Phenanthrolines; Protein Structure, Tertiary; Quinoxalines; Receptors, Glutamate; Uncoupling Agents | 2013 |
Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse.
Topics: Algorithms; Animals; Aspartic Acid; Benzothiadiazines; Calcium; Computer Simulation; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hair Cells, Auditory; Male; Microscopy, Electron; Models, Neurological; Neurotransmitter Agents; Patch-Clamp Techniques; Rana catesbeiana; Signal Transduction; Synaptic Transmission | 2014 |
A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures.
Topics: Allosteric Regulation; Animals; Benzothiadiazines; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Receptors, AMPA; Recombinant Proteins; Synapses; Xenopus laevis | 2015 |
Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties.
Topics: Animals; Benzothiadiazines; Brain; Carrier Proteins; Gene Expression Regulation, Developmental; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Protein Binding; Receptors, AMPA; Sequence Analysis, DNA | 2015 |
Inhibition of calcium-permeable and calcium-impermeable AMPA receptors by perampanel in rat brain neurons.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzothiadiazines; Binding Sites; Brain; CA1 Region, Hippocampal; Calcium; Corpus Striatum; Drug Interactions; Glutamic Acid; Interneurons; Kainic Acid; Neurons; Nitriles; Pyramidal Cells; Pyridones; Rats, Wistar; Receptors, AMPA | 2016 |
Stargazin differentially modulates ampakine gating kinetics and pharmacology.
Topics: Benzothiadiazines; Calcium Channels; Gene Expression Regulation; Glutamic Acid; HEK293 Cells; Humans; Membrane Potentials; Oxazines; Receptors, AMPA | 2018 |