Compounds > cyclosporine

cyclosporine and telaprevir

cyclosporine has been researched along with telaprevir in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's12 (75.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bartenschlager, R; Cecchetti, V; Coelmont, L; Easmon, J; Herdewijn, P; Leyssen, P; Mittendorfer, H; Neyts, J; Paeshuyse, J; Puerstinger, G; Tabarrini, O; Vliegen, I1
Coelmont, L; Dumont, JM; Kaptein, S; Neyts, J; Paeshuyse, J; Vliegen, I; Vuagniaux, G1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alves, K; Garg, V; Lee, JE; Luo, X; Nadkarni, P; van Heeswijk, R1
Charlton, M1
Gerken, G; Herzer, K; Jochum, C; Papadopoulos-Köhn, A; Paul, A; Timm, J1
Chiba, T; Fujimoto, Y; Hashi, S; Hashimoto, E; Ito, T; Kaido, T; Kawai, T; Kikuchi, M; Masuda, S; Matsubara, K; Nishioka, Y; Okuda, Y; Omura, T; Shinke, H; Takahashi, T; Ueda, Y; Uemoto, S; Uesugi, M; Yonezawa, A1
Balsarotti, J; Briley, A; Dufner-Beattie, J; Noueiry, A; O'Guin, A; O'Guin, S; Olivo, PD; Rice, CM; Roth, R; Slomczynska, U; Starkey, G; Wang, B1
Czock, D; Eisenbach, C; Giese, T; Gotthardt, D; Roos, K; Schnitzler, P; Stremmel, W1
Fukuhara, T; Ikegami, T; Itoh, S; Kato, M; Maehara, Y; Matsuura, Y; Nakamura, S; Shirabe, K; Yamamoto, S; Yoshizumi, T1
Cunningham, ME; Davidson-Wright, J; Foster, GR; Javaid, A; Jones, M; Waters, J; Wong, JL1
Antonini, TM; Bonhomme-Faivre, L; Coilly, A; Duclos-Vallée, JC; Furlan, V; Haim-Boukobza, S; Roque-Afonso, AM; Samuel, D; Sebagh, M; Taburet, AM; Teicher, E; Vittecoq, D1
Bellissant, E; Boglione-Kerrien, C; Boudjema, K; Dermu, M; Jezequel, C; Lemaitre, F; Verdier, MC1
Aoki, C; Apriyanto, DR; Arsianti, A; Dewi, BE; Hanafi, M; Hartati, S; Hotta, H; Kardono, LB; Louisa, M; Soebandrio, A; Sudarmono, P; Sudiro, TM1
Adianti, M; Aoki-Utsubo, C; Hafid, AF; Hotta, H; Permanasari, AA; Tumewu, L; Wahyuni, TS; Widyawaruyanti, A1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Trials

1 trial(s) available for cyclosporine and telaprevir

ArticleYear
Effect of telaprevir on the pharmacokinetics of cyclosporine and tacrolimus.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Antiviral Agents; Area Under Curve; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Female; Follow-Up Studies; Hepatitis C; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Middle Aged; Oligopeptides; Tacrolimus; Young Adult

2011

Other Studies

15 other study(ies) available for cyclosporine and telaprevir

ArticleYear
Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Antiviral Agents; Cell Line, Tumor; DNA Helicases; Enzyme Inhibitors; Hepacivirus; Humans; Microbial Sensitivity Tests; Protease Inhibitors; Replicon; RNA-Dependent RNA Polymerase; Virus Replication

2008
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Antiviral Agents; Clinical Trials as Topic; Cyclophilins; Cyclosporine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Hepacivirus; Hepatitis C; Humans; Replicon; Ribavirin; Viral Nonstructural Proteins

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Telaprevir, boceprevir, cytochrome P450 and immunosuppressive agents--a potentially lethal cocktail.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:1

    Topics: Antiviral Agents; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Hepatitis C; Humans; Immunosuppressive Agents; Liver Transplantation; Oligopeptides; Proline; Tacrolimus

2011
[HCV reinfection after liver transplantation - management and first experiences with telaprevir-based triple therapy].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:36

    Topics: Adult; Antiviral Agents; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Liver Transplantation; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Postoperative Complications; Recombinant Proteins; Recurrence; Ribavirin; Tacrolimus; Viral Load

2013
Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:3

    Topics: Aged; Antiviral Agents; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Hepacivirus; Hepatitis C; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver; Liver Transplantation; Male; Middle Aged; Oligopeptides; Protease Inhibitors; Recurrence; RNA; Treatment Outcome

2014
Identification of AP80978, a novel small-molecule inhibitor of hepatitis C virus replication that targets NS4B.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6

    Topics: Adenosine; Antiviral Agents; Biological Assay; Cell Culture Techniques; Cell Line; Cell Survival; Cyclosporine; Furans; Genotype; Hepacivirus; Hepatitis C; High-Throughput Screening Assays; Humans; Luciferases, Renilla; Mutagenesis, Site-Directed; Oligopeptides; Pyridines; Replicon; Thiophenes; Viral Nonstructural Proteins; Virus Replication

2014
Pharmacodynamic monitoring of immunosuppressive effects indicates reduced cyclosporine activity during telaprevir therapy.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2014, Volume: 20, Issue:9

    Topics: Antiviral Agents; Biomarkers; Cyclosporine; Dose-Response Relationship, Immunologic; Drug Interactions; Drug Monitoring; End Stage Liver Disease; Female; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Hepacivirus; Hepatitis C; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Liver Transplantation; Male; Middle Aged; Oligopeptides; Predictive Value of Tests; Recurrence; Retrospective Studies; RNA, Messenger; RNA, Viral; Time Factors; Treatment Outcome; Viral Load

2014
Reduced-dose telaprevir-based triple antiviral therapy for recurrent hepatitis C after living donor liver transplantation.
    Transplantation, 2014, Nov-15, Volume: 98, Issue:9

    Topics: Aged; Anemia; Antiviral Agents; Cohort Studies; Cyclosporine; End Stage Liver Disease; Female; Glomerular Filtration Rate; Haplotypes; Hemoglobins; Hepacivirus; Hepatitis C, Chronic; High-Throughput Nucleotide Sequencing; Humans; Japan; Liver Transplantation; Living Donors; Male; Middle Aged; Mutation; Oligopeptides; Recurrence; RNA, Viral; Treatment Outcome

2014
Development and validation of a "capture-fusion" model to study drug sensitivity of patient-derived hepatitis C.
    Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:4

    Topics: Cell Fusion; Cyclosporine; Drug Resistance, Viral; Genotype; Hepacivirus; Hepatocytes; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Biological; Monocytes; Oligopeptides

2015
Therapy with boceprevir or telaprevir in HIV/hepatitis C virus co-infected patients to treat recurrence of hepatitis C virus infection after liver transplantation.
    AIDS (London, England), 2015, Jan-02, Volume: 29, Issue:1

    Topics: Adult; Antiviral Agents; Coinfection; Cyclosporine; Drug Therapy, Combination; Female; Hepatitis C, Chronic; HIV Infections; Humans; Immunosuppression Therapy; Interferon alpha-2; Interferon-alpha; Liver Transplantation; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Recombinant Proteins; Recurrence; Ribavirin; Tacrolimus; Viral Load

2015
Lack of drug interaction between cyclosporine and telaprevir in a liver transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:1

    Topics: Cyclosporine; Drug Interactions; Drug Monitoring; Hepacivirus; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Liver Transplantation; Male; Middle Aged; Oligopeptides; Serine Proteinase Inhibitors; Transplant Recipients

2015
Anti-Hepatitis C Virus Activity of a Crude Extract from Longan (Dimocarpus longan Lour.) Leaves.
    Japanese journal of infectious diseases, 2016, May-20, Volume: 69, Issue:3

    Topics: Antiviral Agents; Cell Line, Tumor; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Hepacivirus; Hepatocytes; Humans; Inhibitory Concentration 50; Oligopeptides; Plant Extracts; Plant Leaves; Protease Inhibitors; Sapindaceae; Virus Internalization

2016
An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs.
    BMC complementary medicine and therapies, 2021, Oct-12, Volume: 21, Issue:1

    Topics: Antiviral Agents; Artocarpus; Cell Line; Cyclosporine; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Indonesia; Oligopeptides; Plant Extracts; Plant Leaves; Ribavirin

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023