Page last updated: 2024-08-17

cycloserine and kynurenic acid

cycloserine has been researched along with kynurenic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (47.06)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iversen, LL; Leeson, PD1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Peterson, SL1
Beart, PM; Conway, EL; Manallack, DT; Mercer, LD; O'Shea, RD1
Ascher, P; Henderson, G; Johnson, JW1
Bubser, M; Kretschmer, BD; Schmidt, WJ1
Pattarini, R; Pittaluga, A; Raiteri, M1
Löscher, W; Rundfeldt, C; Wlaź, P1
Hamelin, SM; Lehmann, JC1
Engberg, G; Erhardt, S1
Johnson, MS; Moretti, L; Pentikäinen, OT; Settimo, L1
Benedikz, E; Duan, J; Mo-Boquist, LL; Nilsson, A; Sundström, E1
Esashi, A; Furuta, S; Nakagawasai, O; Niijima, F; Sato, T; Satoh, S; Tadano, T; Tan-No, K; Yasuhara, H1
Dubrovina, NI; Zinovyev, DR; Zinovyeva, DV1
Kussius, CL; Popescu, GK1
Camp, M; Debrouse, L; Grant, SG; Gunduz-Cinar, O; Holmes, A; Hurd, B; Kiselycznyk, C; Mishina, M; Plitt, A; Todaro, A1
Baran, H; Kepplinger, B1

Reviews

1 review(s) available for cycloserine and kynurenic acid

ArticleYear
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
    Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding Sites; Cognition; Glycine; Humans; Kynurenic Acid; Neuroprotective Agents; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1994

Other Studies

16 other study(ies) available for cycloserine and kynurenic acid

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
7-Chlorokynurenic acid antagonizes the anticonvulsant activity of D-cycloserine in maximal electroshock seizures.
    Epilepsy research, 1992, Volume: 13, Issue:1

    Topics: Animals; Anticonvulsants; Cycloserine; Dose-Response Relationship, Drug; Electroshock; Injections, Intraventricular; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1992
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate.
    Experimental brain research, 1991, Volume: 86, Issue:3

    Topics: Animals; Autoradiography; Binding, Competitive; Cerebellar Cortex; Cerebral Cortex; Cycloserine; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Serine

1991
Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor.
    The Journal of physiology, 1990, Volume: 430

    Topics: Action Potentials; Animals; Brain; Cells, Cultured; Cerebral Cortex; Cycloserine; Diencephalon; Glycine; Ion Channels; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate

1990
Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: Animals; Behavior, Animal; Corpus Striatum; Cycloserine; Dopamine; Drug Interactions; Excitatory Amino Acid Antagonists; Kynurenic Acid; Locomotion; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Sensitivity and Specificity; Stereotyped Behavior; Strychnine

1995
Putative cognition enhancers reverse kynurenic acid antagonism at hippocampal NMDA receptors.
    European journal of pharmacology, 1995, Jan-16, Volume: 272, Issue:2-3

    Topics: Animals; Cognition; Cycloserine; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Norepinephrine; Psychotropic Drugs; Pyrrolidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1995
Anticonvulsant activity of antagonists and partial agonists for the NMDA receptor-associated glycine site in the kindling model of epilepsy.
    Brain research, 1994, Aug-08, Volume: 653, Issue:1-2

    Topics: Animals; Anticonvulsants; Cycloserine; Differential Threshold; Epilepsy; Female; Glycine; Kindling, Neurologic; Kynurenic Acid; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1994
Effects of putative cognition enhancers on the NMDA receptor by [3H]MK801 binding.
    European journal of pharmacology, 1995, Aug-15, Volume: 281, Issue:3

    Topics: Animals; Binding, Competitive; Cognition; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Kynurenic Acid; Piracetam; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate

1995
Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid.
    Acta physiologica Scandinavica, 2002, Volume: 175, Issue:1

    Topics: Action Potentials; Animals; Antimetabolites; Butyrates; Cycloserine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area

2002
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
    Journal of structural biology, 2004, Volume: 145, Issue:3

    Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water

2004
Characterisation of the human NMDA receptor subunit NR3A glycine binding site.
    Neuropharmacology, 2007, Volume: 52, Issue:4

    Topics: Animals; Binding, Competitive; Brain; Cell Line, Transformed; Cycloserine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Humans; Kynurenic Acid; Models, Molecular; Mutation; Protein Binding; Rats; Receptors, N-Methyl-D-Aspartate; Transfection

2007
Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Agmatine; Animals; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Spinal; Ion Channels; Kynurenic Acid; Mice; Morphine; Neurokinin A; Nociceptors; Pain; Peptide Fragments; Piperidines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Tachykinin; Substance P

2007
N-methyl-D-aspartate receptors and amnesia in mice with depression-like state.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5

    Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cycloserine; Depression; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, Amino Acid

2007
Kinetic basis of partial agonism at NMDA receptors.
    Nature neuroscience, 2009, Volume: 12, Issue:9

    Topics: Action Potentials; Alanine; Amino Acids, Cyclic; Animals; Binding Sites; Cell Line; Cell Membrane; Cycloserine; Excitatory Amino Acid Agents; Glutamates; Glutamic Acid; Glycine; Humans; Kinetics; Kynurenic Acid; Models, Molecular; Rats; Receptors, N-Methyl-D-Aspartate

2009
Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:2

    Topics: Alcoholic Intoxication; Animals; Ataxia; Cycloserine; Disease Models, Animal; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Drug Therapy, Combination; Glycine Plasma Membrane Transport Proteins; Guanylate Kinases; Hypothermia; Kynurenic Acid; Magnesium; Male; Membrane Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Sarcosine; Serine

2013
D-Cycloserine lowers kynurenic acid formation--new mechanism of action.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Aged; Animals; Antibiotics, Antitubercular; Anticonvulsants; Cycloserine; Down-Regulation; Enzyme Inhibitors; Female; Frontal Lobe; Humans; Isoenzymes; Kynurenic Acid; Liver; Male; Middle Aged; Nerve Tissue Proteins; Neurons; Nootropic Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Transaminases

2014