Page last updated: 2024-08-17

cycloserine and clozapine

cycloserine has been researched along with clozapine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Coyle, JT; Darby, DG; Flood, J; Goff, DC; Manoach, DS; Tsai, G1
Amico, E; Evins, AE; Goff, DC; Henderson, DC1
Barczak, A; Carlson, RR; Coyle, JT; Heckers, S; Huganir, RL; Kang, S; Konradi, C; Leveque, JC; Li, XM; MacĂ­as, W; Rajadhyaksha, A1
Tiihonen, J; Tuominen, HJ; Wahlbeck, K1
Javitt, DC1
Hammonds, MD; Kee, BS; Shim, SS1
Diamant, L; Gaisler-Salomon, I; Rubin, C; Weiner, I1

Reviews

4 review(s) available for cycloserine and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis.
    Schizophrenia research, 2005, Jan-01, Volume: 72, Issue:2-3

    Topics: Clozapine; Cycloserine; Dioxoles; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Agents; Glycine; Humans; Hydro-Lyases; Molindone; Piperidines; Schizophrenia

2005
Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients.
    Current opinion in psychiatry, 2006, Volume: 19, Issue:2

    Topics: Antimetabolites; Antipsychotic Agents; Clozapine; Cycloserine; Drug Therapy, Combination; Glutamic Acid; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia

2006
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
    European archives of psychiatry and clinical neuroscience, 2008, Volume: 258, Issue:1

    Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine

2008

Trials

2 trial(s) available for cycloserine and clozapine

ArticleYear
D-cycloserine added to clozapine for patients with schizophrenia.
    The American journal of psychiatry, 1996, Volume: 153, Issue:12

    Topics: Adult; Ambulatory Care; Amino Acids; Clozapine; Cycloserine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Placebos; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1996
A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia.
    Biological psychiatry, 1999, Feb-15, Volume: 45, Issue:4

    Topics: Adult; Antipsychotic Agents; Behavioral Symptoms; Clozapine; Cross-Over Studies; Cycloserine; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Treatment Outcome

1999

Other Studies

5 other study(ies) available for cycloserine and clozapine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Intracellular modulation of NMDA receptor function by antipsychotic drugs.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jun-01, Volume: 20, Issue:11

    Topics: Animals; Antipsychotic Agents; Blotting, Northern; Cells, Cultured; Clozapine; Cycloserine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Neostriatum; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2000
Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Animals; Behavior, Animal; Clozapine; Conditioning, Psychological; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emotions; Fluorobenzenes; Glycine; Glycine Agents; Inhibition, Psychological; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Stress, Psychological; Thirst; Treatment Outcome

2008