cyclophellitol has been researched along with cyclohexanol in 42 studies
Studies (cyclophellitol) | Trials (cyclophellitol) | Recent Studies (post-2010) (cyclophellitol) | Studies (cyclohexanol) | Trials (cyclohexanol) | Recent Studies (post-2010) (cyclohexanol) |
---|---|---|---|---|---|
44 | 0 | 24 | 4,548 | 691 | 1,355 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 11 (26.19) | 18.2507 |
2000's | 6 (14.29) | 29.6817 |
2010's | 18 (42.86) | 24.3611 |
2020's | 7 (16.67) | 2.80 |
Authors | Studies |
---|---|
Atsumi, S; Iinuma, H; Nosaka, C; Umezawa, K | 3 |
Nakata, M; Niwata, Y; Tatsuta, K; Toshima, K; Umezawa, K | 2 |
Umezawa, K; Withers, SG | 1 |
Atsumi, S; Iinuma, H; Iitaka, Y; Naganawa, H; Nakamura, H; Takeuchi, T; Umezawa, K | 1 |
Fung, PH; Shing, TK; Tai, VW; Wong, YS | 1 |
Chong, C; Nakata, M; Niwata, Y; Tatsuta, K; Toshima, K | 1 |
Atsumi, S; Iinuma, H; Nosaka, C; Ochi, Y; Umezawa, K | 1 |
Bismuto, E; Irace, G; Nucci, R; Rossi, M | 1 |
Hembre, EJ; Patterson, DE; Trost, BM | 1 |
Takahashi, H | 1 |
Breithaupt, AT; Collins, W; Kireev, AS; Kornienko, A; Nadein, ON | 1 |
Bundgaard, E; Hansen, FG; Madsen, R | 1 |
Davies, GJ; Gloster, TM; Madsen, R | 1 |
Ikegami, S; Takahashi, H | 1 |
Aerts, JM; Aten, J; Bleijlevens, B; Boot, RG; Donker-Koopman, WE; Florea, BI; Hollak, CE; Hooibrink, B; Kallemeijn, WW; Kramer, G; Li, KY; Ottenhoff, R; Overkleeft, HS; Strijland, A; van den Nieuwendijk, AM; van der Marel, GA; Witte, MD | 1 |
Chen, CF; Ketudat Cairns, JR; Kuaprasert, B; Pengthaisong, S; Withers, SG | 1 |
Aerts, JM; Aten, J; Boot, RG; Codée, JD; Florea, BI; Jiang, J; Kallemeijn, WW; Li, KY; Marques, AR; Ottenhoff, R; Overkleeft, HS; Scheij, S; van den Elst, H; van der Marel, GA; van Roomen, CP; Voorn-Brouwer, TM; Walvoort, MT; Willems, LI; Witte, MD | 1 |
Mondal, S; Prathap, A; Sureshan, KM | 1 |
Chandrasekar, B; Colby, T; Emran Khan Emon, A; Harzen, A; Hong, TN; Jiang, J; Overkleeft, HS; van der Hoorn, RA; Villamor, JG | 1 |
Aerts, JM; Boot, RG; Codée, JD; Donker-Koopman, WE; Jiang, J; Kallemeijn, WW; Li, KY; Overkleeft, HS; van der Marel, GA; Witte, MD | 1 |
Aerts, JM; Boot, RG; Codée, JD; Kallemeijn, WW; Li, KY; Overkleeft, HS; van der Marel, GA; Voorn-Brouwer, TM; Walvoort, MT; Witte, MD | 1 |
Bujons, J; Egido-Gabás, M; Llebaria, A; Trapero, A | 1 |
Aerts, JM; Beenakker, TJ; Codée, JD; Jiang, J; Kallemeijn, WW; Overkleeft, HS; van den Elst, H; van der Marel, GA | 1 |
Chen, HM; Davies, GJ; Jiang, J; Jin, Y; Kötzler, MP; Kwan, DH; Overkleeft, HS; Withers, SG | 1 |
Brayer, GD; Caner, S; Chen, HM; Jiang, J; Nguyen, NT; Overkleeft, H; Withers, SG; Zhang, X | 1 |
Aerts, JM; Ben Bdira, F; Bleijlevens, B; Boot, R; de Haan, A; Florea, BI; Jiang, J; Kallemeijn, W; Overkleeft, HS; Ubbink, M | 1 |
Aerts, JMFG; Artola, M; Beenakker, TJM; Codée, JDC; Davies, GJ; Ferraz, MJ; Hansen, T; Houben, JHPM; Li, KY; Offen, WA; Overkleeft, HS; Raich, L; Rovira, C; van der Marel, GA; van Rijssel, ER; Wander, DPA | 1 |
Absalah, S; Aerts, JMFG; Al-Khakany, H; Boer, DEC; Bouwstra, JA; Dijkhoff, IM; Helder, RWJ; Kallemeijn, WW; Overkleeft, HS; Schreuder, A; van Smeden, J | 1 |
Aerts, JM; Artola, ME; Kallemeijn, WW; Kuo, CL; Kytidou, K; Overkleeft, HS; van Meel, E; Witte, M | 1 |
Aerts, JMFG; Artola, M; Codée, JDC; Florea, BI; Gloster, TM; Hansen, T; He, X; Kermode, AR; Kuo, CL; McMahon, SA; Oehler, V; Overkleeft, HS; van den Elst, H; van der Lienden, M; van der Marel, GA | 1 |
Aerts, JMFG; Artola, M; Futerman, AH; Kallemeijn, WW; Kuo, CL; Lelieveld, LT; Meijer, AH; Mirzaian, M; Overkleeft, HS; Spaink, HP; Vardi, A; Zoutendijk, I | 1 |
Aerts, JMFG; Artola, M; Boot, RG; Codée, JDC; Davies, GJ; Kuo, CL; Lelieveld, LT; Overkleeft, HS; Rowland, RJ; van der Marel, GA | 1 |
Artola, M; Bhatt, AP; Cloer, EW; Davies, GJ; Goldfarb, D; Jariwala, PB; Major, MB; Overkleeft, HS; Pellock, SJ; Redinbo, MR; Roberts, LR; Simpson, JB; Walton, WG | 1 |
Aerts, JMFG; Armstrong, Z; Beenakker, TJM; Boot, RG; Codée, JDC; Davies, GJ; de Boer, C; Debets, MF; Florea, BI; Geurink, PP; Hissink, C; Johnson, R; Kuo, CL; Lahav, D; Liu, B; Ovaa, H; Overkleeft, HS; van der Marel, GM; van der Stelt, M; van Rijssel, ER; Wong, CS; Wu, L | 1 |
Amaki, S; Arakawa, T; Artola, M; Borlandelli, V; Codée, JDC; Coines, J; Davies, GJ; Fushinobu, S; Ishiwata, A; Ito, Y; Linzel, D; McGregor, NGS; Nin-Hill, A; Overkleeft, HS; Rovira, C; van der Marel, GA; Yamada, C | 1 |
Aerts, JMFG; Artola, M; Boot, RG; Ferraz, MJ; Kuo, CL; Lelieveld, LT; Overkleeft, HS; Schröder, SP; Su, Q; Verhoek, M | 1 |
Aerts, JMFG; Armstrong, Z; Beenakker, TJM; Codée, JDC; Davies, GJ; Florea, BI; Kuo, CL; McGregor, NGS; Offen, WA; Overkleeft, HS; Wong, CS | 1 |
Davies, GJ; McGregor, NGS; Overkleeft, HS | 1 |
Aerts, JMFG; Artola, M; Codée, JDC; Davies, GJ; Katzy, RE; Kok, K; Kuo, CL; Lelieveld, LT; Overkleeft, HS; Roig-Zamboni, V; Sulzenbacher, G; van der Marel, GA; Wu, L | 1 |
1 review(s) available for cyclophellitol and cyclohexanol
Article | Year |
---|---|
[Synthetic studies on sugar-related bioactive substances based on the ring transformation].
Topics: Carbohydrates; Catalysis; Cyclization; Cyclohexanols; Cyclohexanones; Drug Design; Inositol; Inositol Phosphates; Lactones; Palladium | 2002 |
41 other study(ies) available for cyclophellitol and cyclohexanol
Article | Year |
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Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice.
Topics: Animals; beta-Glucosidase; beta-N-Acetylhexosaminidases; Brain; Cyclohexanols; Female; Glucosylceramidase; Kidney; Kinetics; Liver; Mice; Mice, Inbred Strains; Muscles; Spleen; Time Factors | 1992 |
Enantiospecific synthesis and biological evaluation of 1,6-epi-cyclophellitol.
Topics: Basidiomycota; beta-Glucosidase; Chemical Phenomena; Chemistry; Crystallization; Cyclohexanols; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism | 1991 |
Cyclophellitol: a naturally occurring mechanism-based inactivator of beta-glucosidases.
Topics: Alcaligenes; beta-Glucosidase; Cyclohexanols; Escherichia coli; Kinetics; Plants; Recombinant Proteins | 1991 |
Syntheses and enzyme inhibiting activities of cyclophellitol analogs.
Topics: beta-Glucosidase; Cyclohexanols | 1991 |
Production, isolation and structure determination of a novel beta-glucosidase inhibitor, cyclophellitol, from Phellinus sp.
Topics: Basidiomycota; beta-Glucosidase; Crystallography; Cyclohexanols; Fermentation; Glucosidases; Molecular Structure | 1990 |
Biological activities of cyclophellitol.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; beta-Glucosidase; Binding, Competitive; Body Weight; Cell Line; Cyclohexanols; Female; Glucosamine; Glucosylceramidase; Indolizines; Mice; Microsomes; Tumor Cells, Cultured | 1990 |
Kinetic studies on cyclophellitol analogues--mechanism-based inactivators.
Topics: alpha-Mannosidase; beta-Glucosidase; Cyclohexanols; Glycoside Hydrolase Inhibitors; Kinetics; Mannosidases; Saccharomyces cerevisiae; Stereoisomerism; Structure-Activity Relationship | 1995 |
A family of cyclophellitol analogs: synthesis and evaluation.
Topics: Cyclohexanols; Drug Stability; Glycoside Hydrolases; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 1993 |
Accumulation of tissue glucosylsphingosine in Gaucher-like mouse induced by the glucosylceramidase inhibitor cyclophellitol.
Topics: Animals; Brain; Cells, Cultured; Cyclohexanols; Disease Models, Animal; Gaucher Disease; Glucosylceramidase; In Vitro Techniques; Liver; Mice; Psychosine; Spleen | 1993 |
Inhibition of experimental metastasis by an alpha-glucosidase inhibitor, 1,6-epi-cyclophellitol.
Topics: alpha-Glucosidases; Animals; Antineoplastic Agents; beta-Glucosidase; Cell Adhesion; Cell Line; Cyclohexanols; Female; Glycoside Hydrolase Inhibitors; Kinetics; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis | 1993 |
Structural and dynamic aspects of beta-glycosidase from mesophilic and thermophilic bacteria by multitryptophanyl emission decay studies.
Topics: beta-Glucosidase; Cyclohexanols; Enzyme Inhibitors; Escherichia coli; Guanidine; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Sulfolobus; Tryptophan | 1999 |
AAA in KAT/DYKAT processes: first- and second-generation asymmetric syntheses of (+)- and (-)-cyclophellitol.
Topics: Agaricales; Anti-HIV Agents; beta-Glucosidase; Catalysis; Cyclohexanols; Enzyme Inhibitors; Methods; Rhenium; Stereoisomerism | 2001 |
Enantiodivergent formal synthesis of (+)- and (-)-cyclophellitol from D-xylose based on the latent symmetry concept.
Topics: Cyclohexanols; Molecular Structure; Stereoisomerism; Xylose | 2005 |
A short synthesis of (+)-cyclophellitol.
Topics: beta-Glucosidase; Cyclohexanols; Enzyme Inhibitors; Molecular Conformation; Stereoisomerism; Xylose | 2005 |
Structural basis for cyclophellitol inhibition of a beta-glucosidase.
Topics: beta-Glucosidase; Crystallography, X-Ray; Cyclohexanols; Enzyme Inhibitors; Enzyme Stability; Hydrolysis; Kinetics; Mass Spectrometry | 2007 |
Synthesis of cyclophellitol utilizing a palladium chloride mediated-Ferrier-II rearrangement.
Topics: Cyclohexanols; Models, Chemical; Molecular Conformation; Palladium; Temperature | 2005 |
Ultrasensitive in situ visualization of active glucocerebrosidase molecules.
Topics: Animals; Boron Compounds; Cells, Cultured; Cyclohexanols; Drug Design; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Gaucher Disease; Glucosylceramidase; Imino Pyranoses; Mice; Microscopy, Fluorescence; Molecular Chaperones | 2010 |
Rice BGlu1 glycosynthase and wild type transglycosylation activities distinguished by cyclophellitol inhibition.
Topics: Carbohydrate Sequence; Cyclohexanols; Disaccharides; Enzyme Inhibitors; Glycosylation; Ligases; Molecular Sequence Data; Mutation; Oryza | 2012 |
Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.
Topics: Animals; Aziridines; Brain; Cellulases; Cyclohexanols; Fluorescent Dyes; Hep G2 Cells; Humans; Isomerism; Mice; Proteomics; Recombinant Proteins | 2012 |
Vinylogy in orthoester hydrolysis: total syntheses of cyclophellitol, valienamine, gabosine K, valienone, gabosine G, 1-epi-streptol, streptol, and uvamalol A.
Topics: Cyclohexanols; Cyclohexanones; Cyclohexenes; Esters; Hexosamines; Hydrolysis; Molecular Conformation | 2013 |
Broad-range glycosidase activity profiling.
Topics: Arabidopsis; Arabidopsis Proteins; Aziridines; Catalytic Domain; Cell Wall; Cyclohexanols; Glycoside Hydrolases; Mass Spectrometry; Molecular Probes; Phylogeny; Proteomics | 2014 |
Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors.
Topics: beta-Glucosidase; Cyclohexanols; Enzyme Inhibitors; Humans | 2014 |
A sensitive gel-based method combining distinct cyclophellitol-based probes for the identification of acid/base residues in human retaining β-glucosidases.
Topics: Amino Acid Substitution; Amino Acids; Animals; Aziridines; beta-Glucosidase; Catalytic Domain; Chlorocebus aethiops; COS Cells; Cyclohexanols; Epoxy Compounds; Humans; Hydrolysis; Immunoblotting; Molecular Probes; Mutagenesis, Site-Directed; Mutation, Missense; Reproducibility of Results; Sodium Azide; Substrate Specificity | 2014 |
Synthesis and evaluation of hydroxymethylaminocyclitols as glycosidase inhibitors.
Topics: alpha-Glucosidases; beta-Glucosidase; Cyclitols; Cyclohexanols; Enzyme Inhibitors; Glucosylceramidase; Kinetics; Structure-Activity Relationship | 2015 |
Comparing Cyclophellitol N-Alkyl and N-Acyl Cyclophellitol Aziridines as Activity-Based Glycosidase Probes.
Topics: alpha-Glucosidases; alpha-L-Fucosidase; Animals; Aziridines; beta-Glucosidase; Cell Line; Chlorocebus aethiops; COS Cells; Cyclohexanols; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes | 2015 |
Chemoenzymatic synthesis of 6-phospho-cyclophellitol as a novel probe of 6-phospho-β-glucosidases.
Topics: Catalytic Domain; Coenzymes; Crystallography, X-Ray; Cyclohexanols; Enzyme Inhibitors; Glucosidases; Molecular Probes; Protein Conformation; Streptococcus pyogenes | 2016 |
Glucosyl epi-cyclophellitol allows mechanism-based inactivation and structural analysis of human pancreatic α-amylase.
Topics: Catalytic Domain; Computer Simulation; Cyclohexanols; Disaccharides; Epoxy Compounds; Humans; Hydrogen Bonding; Inositol; Kinetics; Mass Spectrometry; Models, Molecular; Pancreatic alpha-Amylases; Water; X-Ray Diffraction | 2016 |
Hydrophobic Interactions Contribute to Conformational Stabilization of Endoglycoceramidase II by Mechanism-Based Probes.
Topics: Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Cyclohexanols; Enzyme Stability; Gaucher Disease; Glucosylceramidase; Glycoside Hydrolases; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Probes; Protein Conformation; Recombinant Proteins; Rhodococcus; Structural Homology, Protein | 2016 |
Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.
Topics: alpha-Glucosidases; Cyclohexanols; Glycoside Hydrolase Inhibitors; Models, Molecular; Molecular Structure; Quantum Theory; Thermotoga maritima | 2017 |
In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling.
Topics: Benzoxazines; Boron Compounds; Cyclohexanols; Enzyme Assays; Epoxy Compounds; Fluorescent Dyes; Gene Expression; Glucosides; Glucosylceramidase; Humans; Hymecromone; Skin; Staining and Labeling; Tissue Culture Techniques | 2017 |
Activity-Based Probes for Glycosidases: Profiling and Other Applications.
Topics: Cell Line; Cyclohexanols; Enzyme Assays; Enzyme Inhibitors; Fibroblasts; Fluorescent Dyes; Gaucher Disease; Glucosylceramidase; Glycosphingolipids; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Probes; Staining and Labeling | 2018 |
New Irreversible α-l-Iduronidase Inhibitors and Activity-Based Probes.
Topics: Aziridines; Chromatography, Liquid; Cyclohexanols; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Humans; Iduronidase; Microscopy, Fluorescence; Models, Molecular; Recombinant Proteins; Staining and Labeling; Tandem Mass Spectrometry | 2018 |
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling.
Topics: Animals; beta-Glucosidase; Brain; Cyclohexanols; Disease Models, Animal; Enzyme Assays; Glucosylceramidase; Glycoside Hydrolase Inhibitors; HEK293 Cells; Humans; Inositol; Isoenzymes; Kinetics; Larva; Lysosomes; Mice; Parkinson Disease; Zebrafish | 2019 |
Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish.
Topics: Animals; Cyclohexanols; Disease Models, Animal; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Zebrafish; Zebrafish Proteins | 2019 |
Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling.
Topics: Animals; Bacterial Proteins; Biomarkers; Computational Biology; Cyclohexanols; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Feces; Female; Gastrointestinal Microbiome; Glucuronidase; Glucuronides; Humans; Hydrolysis; Irinotecan; Kinetics; Male; Metabolome; Mice; Models, Molecular; Precision Medicine; Protein Binding; Protein Conformation | 2020 |
Manno-
Topics: Cyclohexanols; Drug Discovery; Enzyme Inhibitors; Humans; Mannosidases; Molecular Structure | 2020 |
Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β-l-Arabinofuranosidase Inhibitor.
Topics: Biocatalysis; Crystallography, X-Ray; Cyclohexanols; Cysteine; Density Functional Theory; Enzyme Inhibitors; Glycoside Hydrolases; Molecular Dynamics Simulation; Molecular Structure | 2021 |
Xylose-Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase.
Topics: Animals; Cells, Cultured; Cyclohexanols; Enzyme Inhibitors; Glucosylceramidase; HEK293 Cells; Humans; Molecular Conformation; Xylose; Zebrafish | 2021 |
Synthesis of broad-specificity activity-based probes for
Topics: beta-Mannosidase; Cyclohexanols; Molecular Conformation; Molecular Probes | 2022 |
Detecting and identifying glycoside hydrolases using cyclophellitol-derived activity-based probes.
Topics: Catalysis; Cyclohexanols; Glycoside Hydrolases | 2022 |
1,6-
Topics: alpha-Glucosidases; Animals; Cyclohexanols; Glucan 1,4-alpha-Glucosidase; Glycogen; Glycogen Storage Disease Type II; Glycoside Hydrolase Inhibitors; Humans; Zebrafish | 2022 |