Page last updated: 2024-08-21

cyclopentane and prostaglandin d2

cyclopentane has been researched along with prostaglandin d2 in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.92)	18.2507
2000's	39 (76.47)	29.6817
2010's	8 (15.69)	24.3611
2020's	2 (3.92)	2.80

Authors

Authors	Studies
Ahrens, PB; Ankel, H; Parker, J	1
Chen, Y; Morrow, JD; Roberts, LJ	1
Chen, Y; Kapahi, P; Karin, M; Natoli, G; Rossi, A; Santoro, MG; Takahashi, T	1
Ghosh, G; Glass, CK; Hsiang, CH; Li, M; Pascual, G; Ricote, M; Sengchanthalangsy, LL; Straus, DS; Welch, JS	1
Alvarez, AM; Boscá, L; Castrillo, A; Hortelano, S	1
Dixon, C; Hilbelink, T; Lu, L; Rovin, BH; Wilmer, WA	1
Furuta, K; Hatanaka, H; Ishikawa, Y; Nakatsuka, D; Namura, S; Satoh, T; Sugie, Y; Suzuki, M; Tomokiyo, K; Watanabe, Y	1
Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C	1
Britti, D; Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Dugo, L; Mazzon, E; Serraino, I; Thiemermann, C; Wayman, NS	1
Bureau, F; Desmet, C; Jaspar, F; Lekeux, P; Mélotte, D; Pastoret, PP; Piette, J; Vanderplasschen, A; Volanti, C	1
Boutaud, O; Chinery, R; Coffey, RJ; Cox, B; Graves-Deal, R; Morrow, JD; Murphey, LJ; Oates, JA; Zackert, WE	1
Satoh, T; Watanabe, Y	1
Cippitelli, M; Di Bona, D; Fionda, C; Frati, L; Lupo, A; Piccoli, M; Santoni, A	1
Ishii, T; Kumazawa, S; Masutani, H; Nakamura, H; Shibata, T; Uchida, K; Yamada, T; Yodoi, J	1
Aburatani, H; Baba, M; Furuta, K; Hatanaka, H; Ishikawa, T; Ishikawa, Y; Nakatsuka, D; Satoh, T; Suzuki, M; Watanabe, Y	1
Di Meglio, P; Di Rosa, M; Ialenti, A; Ianaro, A; Maffia, P; Santoro, MG	1
Erl, W; Vosseler, CA; Weber, PC	1
Cuzzocrea, S; Di Rosa, M; Ialenti, A; Ianaro, A; Maffia, P; Mazzon, E; Santoro, MG	1
Brossart, P; Denzlinger, C; Grünebach, F; Lauber, K; Nencioni, A; Van Parijs, L; Wesselborg, S	1
Kondo, M; Masutani, H; Nakamura, H; Shibata, T; Tanahashi, N; Tanaka, K; Uchida, K; Yamada, T; Yodoi, J	1
Chen, HZ; Rovin, BH; Zhang, X	1
Araki, E; Brownlee, M; Kiritoshi, S; Kukidome, D; Matsumura, T; Matsuo, T; Nishikawa, T; Pestell, RG; Sakai, M; Senokuchi, T; Sonoda, K; Yano, M	1
Emi, M; Maeyama, K	1
Alba, G; Alvarez-Maqueda, M; Bedoya, FJ; Chacón, P; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Pintado, E; Sobrino, F; Vega, A	1
Baud, L; Bellocq, A; Cheron, A; Fouqueray, B; Peltier, J; Perez, J	1
Nikitakis, NG; Sauk, JJ; Siavash, H	1
Cernuda-Morollón, E; Pérez-Sala, D; Sánchez-Gómez, FJ; Stamatakis, K	1
Masuko-Hongo, K	1
Gayarre, J; Pérez-Sala, D; Renedo, M; Stamatakis, K	1
Albicini, M; Asfar, P; Bauer, M; Bracht, H; Brückner, UB; Ehrmann, U; Hauser, B; Iványi, Z; Kick, J; Muth, CM; Radermacher, P; Vogt, J; Wachter, U	1
Figueiredo-Pereira, ME; Ogburn, KD	1
Ciucci, A; Gianferretti, P; Guyot, T; Piva, R; Roberts, SM; Santoro, MG; Snape, TJ	1
Avellano, MI; Gayarre, J; Pérez-Sala, D; Sánchez-Gómez, FJ	1
Avellano, MI; Cañada, FJ; Carrasco, MJ; Gayarre, J; Pérez-Sala, D; Sánchez-Gómez, FJ	1
Blay, J; Lowthers, EL; Richard, CL	1
Jang, SK; Kim, JH; Kim, WJ	1
Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Genovese, T; Mazzon, E; Meli, R; Muià, C	1
Bennett, PR; Lindström, TM; Mehmet, H; Pirianov, G; Terzidou, V; Waddington, SN	1
Bao, B; Choi, JS; Dang, HT; Hong, J; Jung, JH; Lee, HJ; Yoo, ES	1
Birtwistle, J; Bunce, CM; Davies, NJ; Hayden, RE; Mayer, K; Ride, JP; Simpson, PJ	1
Kim, DH; Kim, EH; Na, HK; Surh, YJ	1
Hayakari, M; Mori, F; Shibata, T; Tanji, K; Uchida, K; Wakabayashi, K; Yoshida, H; Zhang, HX	1
Di Maio, R; Graham, SH; Gronenborn, AM; Kodali, RB; Koharudin, LM; Liu, H	1
Freeman, BA; Iwamoto, N; Kawakami, K; Kobayashi, M; Kumagai, Y; Li, L; Nakajima, H; Nakajima-Takagi, Y; Ohashi, K; Tsujita, T; Yamamoto, M	1
Agúndez, JA; Ayuso, P; Dorado, CG; Pajares, MA; Pérez-Sala, D; Sánchez-Gómez, FJ	1
Ahmad, M; Graham, SH; Hickey, RW; Li, W; Liu, H; Miller, TM; Pascoe, JL; Poloyac, SM; Rose, ME	1
Bretscher, P; Carreira, EM; Egger, J; Fischer, S; Freigang, S; Kopf, M	1
Fischer, K; Hölscher, C; Lansing, H; Lutterbey, MC; Meyer, T; von Schaewen, A	1
Chistyakov, DV; Chistyakov, VV; Goriainov, SV; Grabeklis, S; Reiser, G; Sergeeva, MG	1
Broz, P; Carreira, EM; Ebner, C; Feng, Q; Kopf, M; Muri, J; Shamshiev, A; Tortola, L; Wolleb, H	1
Cheung, KH; Huang, SY; Iyaswamy, A; Krishnamoorthi, S; Li, M; Liu, J; Lu, JH; Song, JX; Sreenivasmurthy, SG; Su, CF; Tan, JQ; Tong, BC; Wang, ZY; Wu, JX; Yang, CB; Zhu, Z	1

Reviews

2 review(s) available for cyclopentane and prostaglandin d2

Article	Year
[Cyclopentenone prostaglandin derivatives as neuroprotective compounds]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2002, Volume: 47, Issue:15 Topics: Animals; Brain; Cyclopentanes; Drug Design; Humans; Nerve Growth Factors; Prostaglandin D2; Prostaglandins; Prostaglandins A	2002
[Role of prostaglandins in rheumatoid arthritis]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1 Topics: Animals; Apoptosis; Arthritis, Rheumatoid; Cartilage, Articular; Cyclopentanes; Dinoprostone; Humans; Inflammation Mediators; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Synovial Membrane	2005

Other Studies

49 other study(ies) available for cyclopentane and prostaglandin d2

Article	Year
Antiviral effect of cyclopentenone prostaglandins on vesicular stomatitis virus replication. Antiviral research, 1995, Volume: 26, Issue:1 Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cricetinae; Cyclopentanes; DNA-Directed RNA Polymerases; Glutathione; Leukemia L1210; Mice; Prostaglandin D2; Prostaglandins; Prostaglandins A; RNA; Transcription, Genetic; Vesicular stomatitis Indiana virus; Viral Proteins; Virus Replication	1995
Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway. The Journal of biological chemistry, 1999, Apr-16, Volume: 274, Issue:16 Topics: Animals; Arachidonic Acid; Cyclopentanes; Humans; Liver; Mass Spectrometry; Oxidation-Reduction; Prostaglandin D2; Prostaglandins A; Rats	1999
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature, 2000, Jan-06, Volume: 403, Issue:6765 Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; COS Cells; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; I-kappa B Kinase; Jurkat Cells; Molecular Sequence Data; NF-kappa B; Prostaglandin D2; Prostaglandins A; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	2000
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proceedings of the National Academy of Sciences of the United States of America, 2000, Apr-25, Volume: 97, Issue:9 Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclopentanes; Glutathione Transferase; HeLa Cells; Humans; Isoenzymes; Membrane Proteins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins A; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection	2000
Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages. Journal of immunology (Baltimore, Md. : 1950), 2000, Dec-01, Volume: 165, Issue:11 Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cell Line; Cyclopentanes; Drug Synergism; Inflammation Mediators; Macrophage Activation; Macrophages; MAP Kinase Signaling System; Mice; Microbodies; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Superoxides; Transcription Factors	2000
A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma. Biochemical and biophysical research communications, 2001, Feb-16, Volume: 281, Issue:1 Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glomerular Mesangium; Humans; Hypoglycemic Agents; Immunologic Factors; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors	2001
Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins. Journal of neurochemistry, 2001, Volume: 77, Issue:1 Topics: Animals; Biotin; Brain Ischemia; Cell Survival; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microinjections; Nerve Growth Factors; Neurites; Neurons; Neuroprotective Agents; Prostaglandin D2; Prostaglandins; Structure-Activity Relationship	2001
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. Journal of leukocyte biology, 2001, Volume: 69, Issue:4 Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha	2001
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. Molecular pharmacology, 2002, Volume: 61, Issue:5 Topics: Animals; Arthritis, Experimental; Carrageenan; Cyclopentanes; Disease Models, Animal; Immunohistochemistry; Immunologic Factors; Inflammation; Male; Mice; Mice, Inbred BALB C; Pleurisy; Prostaglandin D2	2002
A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. Journal of immunology (Baltimore, Md. : 1950), 2002, May-15, Volume: 168, Issue:10 Topics: Adjuvants, Immunologic; Cells, Cultured; Cyclopentanes; Cytokines; Dose-Response Relationship, Immunologic; Enzyme Activation; HeLa Cells; Humans; Inflammation Mediators; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Prostaglandin D2; Prostaglandins; Prostaglandins A; Protein Processing, Post-Translational; Reactive Oxygen Species; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells	2002
Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione. Biochimica et biophysica acta, 2002, Sep-05, Volume: 1584, Issue:1 Topics: Antineoplastic Agents; Chromatography, Liquid; Colorectal Neoplasms; Cyclopentanes; Glutathione; Humans; Mass Spectrometry; Prostaglandin D2; Time Factors; Tumor Cells, Cultured	2002
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms. Journal of immunology (Baltimore, Md. : 1950), 2003, May-01, Volume: 170, Issue:9 Topics: Animals; Apoptosis; Cell Line, Transformed; Cyclopentanes; DNA-Binding Proteins; Early Growth Response Protein 1; Fas Ligand Protein; fas Receptor; Gene Silencing; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Humans; Hybridomas; Immediate-Early Proteins; Jurkat Cells; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Mice; Peroxisomes; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Transcription Factors	2003
Thioredoxin as a molecular target of cyclopentenone prostaglandins. The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28 Topics: Amino Acid Sequence; Biotinylation; Cell Death; Cyclopentanes; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunoblotting; Models, Chemical; Molecular Sequence Data; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Peptides; Prostaglandin D2; Prostaglandins; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxins; Transfection; Tumor Cells, Cultured	2003
Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress. The European journal of neuroscience, 2003, Volume: 17, Issue:11 Topics: Animals; Antineoplastic Agents; Bilirubin; Biliverdine; Blotting, Western; Cell Line; Cell Survival; Cyclopentanes; Excitatory Amino Acids; Fluorescent Antibody Technique; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Luminescent Proteins; Membrane Proteins; Mice; Neurons; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Prostaglandin D2; Prostaglandins; Prostaglandins A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transfection	2003
Anti-inflammatory activity of 15-deoxy-delta12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response. Molecular pharmacology, 2003, Volume: 64, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclopentanes; DNA-Binding Proteins; Edema; Heat Shock Transcription Factors; Heat-Shock Proteins; Heat-Shock Response; HSP72 Heat-Shock Proteins; Male; Prostaglandin D2; Rats; Rats, Wistar; Time Factors; Transcription Factors	2003
Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis. Biochemical and biophysical research communications, 2003, Jul-25, Volume: 307, Issue:2 Topics: Apoptosis; Cell Line; Cyclopentanes; Endothelium, Vascular; Humans; Molecular Structure; Prostaglandin D2; Prostaglandins	2003
2-Cyclopenten-1-one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF-kappaB. FEBS letters, 2003, Oct-09, Volume: 553, Issue:1-2 Topics: Angioplasty, Balloon, Coronary; Animals; Carotid Arteries; Cell Division; Coronary Restenosis; Cyclopentanes; Electrophoretic Mobility Shift Assay; Intercellular Adhesion Molecule-1; Male; NF-kappa B; Prostaglandin D2; Rats; Rats, Wistar; Tunica Intima	2003
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. Journal of immunology (Baltimore, Md. : 1950), 2003, Nov-15, Volume: 171, Issue:10 Topics: Apoptosis; Cyclopentanes; Down-Regulation; Growth Inhibitors; Humans; Intracellular Membranes; Jurkat Cells; Lymphocyte Activation; Membrane Potentials; Mitochondria; Oxidative Stress; Permeability; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Rosiglitazone; Signal Transduction; T-Lymphocyte Subsets; Thiazolidinediones; Transcription Factors	2003
An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. Biochemistry, 2003, Dec-02, Volume: 42, Issue:47 Topics: Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cyclopentanes; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Immunologic Factors; Membrane Proteins; Multienzyme Complexes; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Proteins; Rats; Structure-Activity Relationship; Thioredoxins; Transfection; Tumor Suppressor Protein p53	2003
Unexpected sensitivity of synthetic Renilla luciferase control vectors to treatment with a cyclopentenone prostaglandin. BioTechniques, 2003, Volume: 35, Issue:6 Topics: Animals; Anthozoa; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Genetic Variation; Humans; Kidney; Luciferases; Prostaglandin D2; Prostaglandins; Transfection	2003
15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB. Biochemical and biophysical research communications, 2004, Feb-13, Volume: 314, Issue:3 Topics: Animals; Base Sequence; Cell Division; Cell Line; Cyclopentanes; DNA; Electrophoretic Mobility Shift Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lipoproteins, LDL; Luciferases; Macrophages; Male; Mice; Mice, Inbred C3H; NF-kappa B; Promoter Regions, Genetic; Prostaglandin D2; Thymidine; Transcriptional Activation; Transfection	2004
The biphasic effects of cyclopentenone prostaglandins, prostaglandin J(2) and 15-deoxy-Delta(12,14)-prostaglandin J(2) on proliferation and apoptosis in rat basophilic leukemia (RBL-2H3) cells. Biochemical pharmacology, 2004, Apr-01, Volume: 67, Issue:7 Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Division; Cyclopentanes; Drug Interactions; Enzyme Inhibitors; Histamine; Leukemia, Basophilic, Acute; Prostaglandin D2; Prostaglandins; Rats; Tumor Cells, Cultured	2004
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21 Topics: Acetylcysteine; Allopurinol; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cyclic N-Oxides; Cyclopentanes; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ions; Lymphocytes; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenanthrolines; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Temperature; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Xanthine Oxidase	2004
15-deoxy-Delta12,14-prostaglandin J2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor gamma-independent process. Journal of immunology (Baltimore, Md. : 1950), 2004, Jun-15, Volume: 172, Issue:12 Topics: Animals; Cell Line; Chemokine CCL2; Cyclopentanes; Dexamethasone; Glucocorticoids; Humans; Macrophages; Mice; Monocytes; Prostaglandin D2; Radioligand Assay; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Signal Transduction; Transcription Factors; Transcription, Genetic; U937 Cells	2004
Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells. Cancer letters, 2004, Jul-28, Volume: 211, Issue:1 Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclopentanes; ErbB Receptors; Humans; Mouth Neoplasms; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Transcription Factors	2004
Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes. Molecular pharmacology, 2004, Volume: 66, Issue:5 Topics: Animals; Biotinylation; Cell Nucleus; Cells, Cultured; Cyclooxygenase 2; Cyclopentanes; Cytosol; Gene Silencing; Glomerular Mesangium; Inflammation; Intercellular Adhesion Molecule-1; Isoenzymes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisome Proliferator-Activated Receptors; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Proteins; Rats; Sulfhydryl Compounds; Transfection	2004
Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione. FEBS letters, 2005, Oct-24, Volume: 579, Issue:25 Topics: Animals; Cyclopentanes; Glutathione; Mice; NIH 3T3 Cells; Prostaglandin D2; Prostaglandins A; Proteins	2005
Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia. Intensive care medicine, 2006, Volume: 32, Issue:5 Topics: Animals; Cyclopentanes; Endotoxemia; Europe; Hypotension; Immunologic Factors; Oxidative Stress; Prospective Studies; Prostaglandin D2; Prostaglandins; Random Allocation; Respiration, Artificial; Swine	2006
Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates. The Journal of biological chemistry, 2006, Aug-11, Volume: 281, Issue:32 Topics: Actins; alpha-Synuclein; Cell Line, Tumor; Centrosome; Cyclopentanes; Cytoskeleton; Endoplasmic Reticulum; Humans; Inflammation; Kinetics; Microtubules; Neurodegenerative Diseases; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Ubiquitin	2006
Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway. Molecular pharmacology, 2006, Volume: 70, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Arachidonic Acid; Breast Neoplasms; Caspases; Cyclopentanes; Down-Regulation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; I-kappa B Kinase; Inhibitor of Apoptosis Proteins; NF-kappa B; Prostaglandin D2; Receptors, Estrogen; Tumor Cells, Cultured	2006
Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival. Archives of biochemistry and biophysics, 2007, Jan-15, Volume: 457, Issue:2 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cyclopentanes; Enzyme Activation; Glutathione S-Transferase pi; Humans; Mice; Molecular Sequence Data; Prostaglandin D2; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2007
Modification of proteins by cyclopentenone prostaglandins is differentially modulated by GSH in vitro. Annals of the New York Academy of Sciences, 2007, Volume: 1096 Topics: Anti-Inflammatory Agents; Biotinylation; Cyclopentanes; Cystine; Dose-Response Relationship, Drug; Gastrointestinal Agents; Gene Expression Regulation; Glutathione; Humans; In Vitro Techniques; Oxygen; Prostaglandin D2; Prostaglandins; Protein Binding; Recombinant Proteins; Transcription Factors	2007
15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. Experimental cell research, 2007, Oct-01, Volume: 313, Issue:16 Topics: Animals; Carcinoma; Cell Line, Tumor; Cyclopentanes; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; NF-kappa B; PPAR gamma; Prostaglandin D2; Receptors, CXCR4; Rosiglitazone; Thiazolidinediones; Time Factors	2007
Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A. The EMBO journal, 2007, Dec-12, Volume: 26, Issue:24 Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arsenites; Chromans; Cyclopentanes; Cytoplasmic Granules; Dinoprostone; Emetine; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-4A; Gene Expression Regulation; HeLa Cells; Humans; Hypoglycemic Agents; Inflammation; Poly(A)-Binding Proteins; PPAR gamma; Prostaglandin D2; Prostaglandins A; Protein Biosynthesis; Protein Synthesis Inhibitors; Rosiglitazone; Signal Transduction; Sodium Compounds; T-Cell Intracellular Antigen-1; Thiazolidinediones; TNF Receptor-Associated Factor 2; Troglitazone; Tumor Necrosis Factor-alpha	2007
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. Shock (Augusta, Ga.), 2008, Volume: 30, Issue:2 Topics: Animals; Cyclization; Cyclopentanes; Disease Models, Animal; Inflammation Mediators; Ligands; Male; Mice; Mice, Inbred Strains; Neutrophil Infiltration; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Prostaglandin D2; Random Allocation; Recovery of Function; Severity of Illness Index; Spinal Cord Injuries	2008
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. Endocrinology, 2009, Volume: 150, Issue:2 Topics: Animals; Animals, Newborn; Animals, Outbred Strains; Anti-Inflammatory Agents; Cyclopentanes; Drug Evaluation, Preclinical; Female; Inflammation; Lipopolysaccharides; Mice; Myometrium; NF-kappa B; Obstetric Labor, Premature; Phospholipases A2; Phosphorylation; Pregnancy; Prostaglandin D2; Time Factors; Uterine Diseases; Uterus	2009
New jasmonate analogues as potential anti-inflammatory agents. Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24 Topics: Acetates; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclopentanes; Interleukin-6; Lipopolysaccharides; Mice; Nitric Oxide; Oxylipins; Prostaglandin D2; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2008
AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects. Cancer research, 2009, Jun-01, Volume: 69, Issue:11 Topics: 20-Hydroxysteroid Dehydrogenases; Acetates; Cell Survival; Cells, Cultured; Cyclopentanes; Drug Delivery Systems; Drug Evaluation, Preclinical; Enzyme Inhibitors; HL-60 Cells; Humans; Hydroxyprostaglandin Dehydrogenases; Isoenzymes; Leukemia, Myeloid; Mitochondria; Models, Biological; Oxylipins; Prostaglandin D2; Reactive Oxygen Species	2009
Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells. Annals of the New York Academy of Sciences, 2009, Volume: 1171 Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell-Free System; Cyclopentanes; Cytosol; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Female; Humans; Immunohistochemistry; Microscopy, Confocal; Molecular Structure; Prostaglandin D2; Prostaglandins A; Protein Binding; Time Factors; Tumor Suppressor Protein p53	2009
Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). Experimental neurology, 2010, Volume: 222, Issue:2 Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Cell Line; Cyclopentanes; Cytoplasm; DNA-Binding Proteins; Female; Gene Expression Regulation; Humans; Immunologic Factors; Male; Middle Aged; Neuroblastoma; Prostaglandin D2; Spinal Cord; Subcellular Fractions	2010
Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. Proceedings of the National Academy of Sciences of the United States of America, 2010, Apr-13, Volume: 107, Issue:15 Topics: Animals; Cyclopentanes; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mutation; Parkinson Disease; Prostaglandin D2; Protein Denaturation; Rats; Rats, Sprague-Dawley; Ubiquitin Thiolesterase	2010
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. Genes to cells : devoted to molecular & cellular mechanisms, 2011, Volume: 16, Issue:1 Topics: Animals; Animals, Genetically Modified; Carrier Proteins; Cell Line; Cells, Cultured; Cyclopentanes; Cysteine; Fatty Acids; Green Fluorescent Proteins; Hydrogen Peroxide; NF-E2-Related Factor 2; Oleic Acids; Oxidative Stress; Prostaglandin D2; Prostaglandins; Trans-Activators; Zebrafish; Zebrafish Proteins	2011
Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs. Inflammation & allergy drug targets, 2013, Volume: 12, Issue:3 Topics: Cell-Free System; Cyclopentanes; Glutathione S-Transferase pi; Humans; Hydrocarbons, Aromatic; Inflammation; Inflammation Mediators; Jurkat Cells; Metabolic Detoxication, Phase II; Molecular Targeted Therapy; Oxidation-Reduction; Prostaglandin D2; Protein Multimerization; Reactive Oxygen Species; Signal Transduction	2013
Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites. Neurotoxicology, 2013, Volume: 39 Topics: Animals; Apoptosis; Carbazoles; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Dose-Response Relationship, Drug; Embryo, Mammalian; Hypoxia; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Knockout; Neurons; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Sulfonamides	2013
Total Synthesis of Prostaglandin 15d-PGJ(2) and Investigation of its Effect on the Secretion of IL-6 and IL-12. Organic letters, 2015, Sep-04, Volume: 17, Issue:17 Topics: Cyclopentanes; Cytokines; Interleukin-12; Interleukin-6; Molecular Structure; Prostaglandin D2; Structure-Activity Relationship	2015
Defects in Peroxisomal 6-Phosphogluconate Dehydrogenase Isoform PGD2 Prevent Gametophytic Interaction in Arabidopsis thaliana. Plant physiology, 2016, Volume: 171, Issue:1 Topics: Alleles; Arabidopsis; Arabidopsis Proteins; Cloning, Molecular; Cyclopentanes; Cytosol; DNA, Bacterial; DNA, Plant; Germ Cells, Plant; Germination; Mutagenesis, Site-Directed; Nitric Oxide; Oxylipins; Pentose Phosphate Pathway; Peroxisomes; Phosphogluconate Dehydrogenase; Plant Leaves; Plastids; Pollen; Prostaglandin D2; Prostaglandins D; Protein Isoforms; Seeds; Sequence Analysis, Protein	2016
Astrocytes synthesize primary and cyclopentenone prostaglandins that are negative regulators of their proliferation. Biochemical and biophysical research communications, 2018, 06-02, Volume: 500, Issue:2 Topics: Animals; Astrocytes; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Cyclopentanes; Lipopolysaccharides; PPAR gamma; Prostaglandin D2; Prostaglandins; Prostaglandins A; Rats, Wistar; Tandem Mass Spectrometry	2018
Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways. Cell reports, 2020, 03-31, Volume: 30, Issue:13 Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Caspase 8; CD40 Antigens; Cell Death; Cell Differentiation; Cyclopentanes; Dendritic Cells; Inflammasomes; Inflammation; Interleukins; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mitochondria; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Oxidation-Reduction; Phenotype; Prostaglandin D2; Prostaglandins; Signal Transduction; Th1 Cells; Toll-Like Receptors; Transcription, Genetic; Up-Regulation	2020
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2. Acta pharmacologica Sinica, 2022, Volume: 43, Issue:5 Topics: Apoptosis; Autophagy; Cyclopentanes; Prostaglandin D2; Prostaglandins; Reactive Oxygen Species	2022