cyclopentane has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 44 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 39 (88.64) | 18.2507 |
2000's | 3 (6.82) | 29.6817 |
2010's | 1 (2.27) | 24.3611 |
2020's | 1 (2.27) | 2.80 |
Authors | Studies |
---|---|
Chen, CH; Sugai, M; Wu, HC | 1 |
Donaldson, JG; Finazzi, D; Klausner, RD | 1 |
Helms, JB; Rothman, JE | 1 |
Bolscher, J; Feltkamp, C; Ploegh, H; Tan, A | 1 |
Ktistakis, NT; Linder, ME; Roth, MG | 1 |
Kreis, TE; Robinson, MS | 1 |
Kahn, RA; Melançon, P; Taylor, TC | 1 |
Banting, G; Reaves, B | 1 |
Schulz, I; Zeuzem, S; Zimmermann, P | 1 |
Donaldson, JG; Kahn, RA; Klausner, RD; Lippincott-Schwartz, J | 1 |
Donaldson, JG; Klausner, RD; Lippincott-Schwartz, J | 1 |
Barthel, A; Nickel, W; Söling, HD; Tonko, C | 1 |
Andersson, LM; Warburton, MJ | 1 |
De Matteis, MA; Di Tullio, G; Kahn, RA; Luini, A; Santini, G | 1 |
Narula, N; Stow, JL | 1 |
Brown, HA; Ktistakis, NT; Roth, MG; Sternweis, PC | 1 |
Melançon, P; Spiro, DJ; Taylor, TC; Wessling-Resnick, M | 1 |
Carnell, L; Moore, HP | 1 |
Ball, CL; Robinson, MS; Seaman, MN | 1 |
Sahara, Y; Westbrook, GL | 1 |
Firestone, GL; Jen, TI; Kain, SR | 1 |
Kahn, RA; Randazzo, PA; Rulka, C; Yang, YC | 1 |
Adamik, R; Haun, RS; Moss, J; Tsai, SC; Vaughan, M | 1 |
Gomez, M; Kreis, TE; Mellman, I; Sheff, D; Whitney, JA | 1 |
Chabre, M; Chardin, P; Franco, M; Paris, S | 1 |
Boman, AL; Carroll, K; Cavenagh, MM; Kahn, RA; Mellman, I; Rosenwald, AG; Whitney, JA; Zhang, Cj | 1 |
Hong, W; Lowe, SL; Wong, SH | 1 |
Anderson, TJ; Gleeson, PA; Griffiths, G; Matheson, F; Stow, JL; Toh, BH | 1 |
Adamik, R; Meacci, E; Moss, J; Tsai, SC; Vaughan, M | 1 |
Cleves, AE; Clift-O'Grady, L; Kelly, RB | 1 |
Gant, TM; Wilson, KL | 1 |
Cario-Toumaniantz, C; Chardin, P; Loirand, G; Pacaud, P | 1 |
Barritt, GJ; Fernando, KC; Gregory, RB; Katsis, F; Kemp, BE | 1 |
Exton, JH; Guillemain, I | 1 |
Bacon, KB; Dairaghi, DJ; Schall, TJ | 1 |
Donaldson, JG; Moss, J; Sata, M; Vaughan, M | 1 |
Bhullar, RP; Fleming, N; Li, L; Mellow, L | 1 |
Cuconati, A; Molla, A; Wimmer, E | 1 |
Bonifacino, JS; Dell'Angelica, EC; Ooi, CE | 1 |
Amornraksa, K; Biesmans, I; Lesage, AS; Lindsay, KB; Pyne, SG; Schafer, K; Skelton, BW; Ung, AT; Van der Linden, I; White, AH; Wouters, R | 1 |
Froestl, W; Kaupmann, K; Koller, M; Lampert, C; Lingenhoehl, K; Mosbacher, J; Pozza, MF; Urwyler, S | 1 |
Boeckler, F; Gmeiner, P; Hübner, H; Schlotter, K | 1 |
Brown, JW; Ma, J; Moeller, A; Nimmrich, V; Rueter, LE; Schmidt, M; Turner, SC; van der Kam, E; Zhang, M | 1 |
Brizzi, A; Castelli, MP; Corelli, F; Mostallino, R; Mugnaini, C | 1 |
44 other study(ies) available for cyclopentane and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
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Bacterial ADP-ribosyltransferase with a substrate specificity of the rho protein disassembles the Golgi apparatus in Vero cells and mimics the action of brefeldin A.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Biomarkers; Brefeldin A; Ceramides; Coatomer Protein; Colforsin; Cyclopentanes; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Mannosidases; Microtubule-Associated Proteins; Poly(ADP-ribose) Polymerases; Rho Factor; Staphylococcus aureus; Substrate Specificity; Vero Cells | 1992 |
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein.
Topics: ADP-Ribosylation Factors; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Intracellular Membranes; Recombinant Proteins; Trypsin | 1992 |
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF.
Topics: ADP-Ribosylation Factors; Animals; Brefeldin A; Coatomer Protein; Cyclopentanes; Golgi Apparatus; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Intracellular Membranes; Liver; Membrane Proteins; Microtubule-Associated Proteins; Rats; Recombinant Proteins | 1992 |
Retrograde transport from the Golgi region to the endoplasmic reticulum is sensitive to GTP gamma S.
Topics: alpha 1-Antitrypsin; Bacterial Proteins; Biological Transport; Brefeldin A; Cell Membrane Permeability; Cyclopentanes; Endoplasmic Reticulum; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Electron; Sialic Acids; Sialyltransferases; Streptolysins; Tumor Cells, Cultured | 1992 |
Action of brefeldin A blocked by activation of a pertussis-toxin-sensitive G protein.
Topics: Brefeldin A; Cell Compartmentation; Cell Membrane Permeability; Coatomer Protein; Cyclopentanes; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Microtubule-Associated Proteins; Peptides; Pertussis Toxin; Protein Binding; Virulence Factors, Bordetella; Wasp Venoms | 1992 |
Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: effects of brefeldin A and G protein activators.
Topics: Adaptor Protein Complex alpha Subunits; Adaptor Protein Complex gamma Subunits; Adaptor Proteins, Vesicular Transport; Aluminum; Aluminum Compounds; Blotting, Western; Brefeldin A; Cell Line; Coatomer Protein; Cyclopentanes; Fluorides; Fluorine; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Microscopy, Fluorescence; Microtubule-Associated Proteins; Proteins | 1992 |
Two distinct members of the ADP-ribosylation factor family of GTP-binding proteins regulate cell-free intra-Golgi transport.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Aluminum; Aluminum Compounds; Biological Transport; Brefeldin A; Cell-Free System; Cyclopentanes; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Viral Proteins | 1992 |
Perturbation of the morphology of the trans-Golgi network following Brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Cells, Cultured; Cyclopentanes; Fluorescent Antibody Technique; Glycoproteins; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Membrane Glycoproteins; Membrane Proteins; Nocodazole; Rats | 1992 |
Guanosine nucleotides modulate the inhibitory effect of brefeldin A on protein secretion.
Topics: Animals; Brefeldin A; Cells, Cultured; Cholecystokinin; Cyclopentanes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Male; Pancreas; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains | 1991 |
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein.
Topics: ADP-Ribosylation Factors; Aluminum; Aluminum Compounds; Animals; Biological Transport; Brefeldin A; CHO Cells; Coatomer Protein; Cricetinae; Cyclopentanes; Endoplasmic Reticulum; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Membranes; Microtubule-Associated Proteins | 1991 |
Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus.
Topics: Adenosine Triphosphate; Aluminum; Aluminum Compounds; Animals; Brefeldin A; Cell Membrane Permeability; Cells, Cultured; Cyclopentanes; Cytosol; Fluorides; Fluorine; Golgi Apparatus; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Proteins; Molecular Weight | 1991 |
Sorting and budding of constitutive secretory vesicles in hepatocytes and hepatoma cells.
Topics: Animals; Brefeldin A; Carrier Proteins; Cell Line; Cyclopentanes; Cytoplasmic Granules; Glycoproteins; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heparan Sulfate Proteoglycans; Heparitin Sulfate; Liver; Liver Neoplasms, Experimental; Membrane Glycoproteins; Membrane Proteins; Proteoglycans; Rats; SNARE Proteins; Tumor Cells, Cultured; Vesicular Transport Proteins | 1995 |
Intracellular degradation of type I collagen and fibronectin in human lung fibroblasts: evidence against degradation in pre-lysosomal compartments.
Topics: 2,2'-Dipyridyl; Biological Transport; Brefeldin A; Canavanine; Cell Line; Cell Membrane Permeability; Chloroquine; Collagen; Cyclopentanes; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fibroblasts; Fibronectins; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxybenzoates; Lung; Monensin; Organelles; Protein Folding; Protein Synthesis Inhibitors | 1995 |
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex.
Topics: ADP-Ribosylation Factors; Aluminum; Animals; Brefeldin A; Cell Membrane Permeability; Coatomer Protein; Cyclopentanes; Enzyme Activation; Fluorine; Glycosaminoglycans; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Microtubule-Associated Proteins; Naphthalenes; Phorbol Esters; Polycyclic Compounds; Protein Binding; Protein Kinase C; Rats; Receptors, IgE; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Distinct coated vesicles labeled for p200 bud from trans-Golgi network membranes.
Topics: Aluminum Compounds; Animals; Brefeldin A; Cell Line; Coated Pits, Cell-Membrane; Coatomer Protein; Cyclopentanes; Cytosol; Fluorescent Antibody Technique; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Insecta; Kidney; Liver; Membrane Proteins; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Phosphoproteins; Protein Binding; Protein Synthesis Inhibitors; Rats | 1995 |
Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.
Topics: ADP-Ribosylation Factors; Animals; Brefeldin A; Carrier Proteins; Cell Fractionation; Cell Line; CHO Cells; Cricetinae; Cyclopentanes; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Orthomyxoviridae; Phospholipase D; Protein Binding; Protein Synthesis Inhibitors | 1995 |
Cytosolic ADP-ribosylation factors are not required for endosome-endosome fusion but are necessary for GTP gamma S inhibition of fusion.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; Cytosol; Endosomes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Membrane Fusion | 1995 |
Transport via the regulated secretory pathway in semi-intact PC12 cells: role of intra-cisternal calcium and pH in the transport and sorting of secretogranin II.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Brefeldin A; Calcimycin; Calcium; Cell Membrane; Chromogranins; Cyclopentanes; Cytosol; Exocytosis; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Hydrogen-Ion Concentration; Kinetics; Membrane Fusion; Nigericin; Organelles; PC12 Cells; Pituitary Neoplasms; Pro-Opiomelanocortin; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proteins; Rats; Tumor Cells, Cultured | 1994 |
Targeting and mistargeting of plasma membrane adaptors in vitro.
Topics: Adaptor Protein Complex alpha Subunits; Adaptor Protein Complex beta Subunits; Adaptor Protein Complex gamma Subunits; Adaptor Proteins, Vesicular Transport; Animals; Biological Transport; Brefeldin A; Calcium; Cell Line; Cell Membrane; Cell Nucleus; Coated Pits, Cell-Membrane; Cyclopentanes; Cytoplasm; Fluorescent Antibody Technique; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Proteins; Rats | 1993 |
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons.
Topics: Alanine; Animals; Animals, Newborn; Barium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Kinetics; Membrane Potentials; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tetrodotoxin; Time Factors; Virulence Factors, Bordetella | 1993 |
Glucocorticoid-regulated trafficking of mouse mammary tumor virus proteins in permeabilized hepatoma cells. Requirements of intracellular membrane transport for maturation of the cytoplasmic phosphorylated polyprotein.
Topics: Animals; Antiviral Agents; Bacterial Proteins; Brefeldin A; Cell Membrane Permeability; Clone Cells; Cyclopentanes; Cytoplasm; Dexamethasone; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Guanosine 5'-O-(3-Thiotriphosphate); Liver Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Models, Biological; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Rats; Streptolysins; Tumor Cells, Cultured; Viral Proteins | 1993 |
Activation of ADP-ribosylation factor by Golgi membranes. Evidence for a brefeldin A- and protease-sensitive activating factor on Golgi membranes.
Topics: ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Brain; Brefeldin A; Carrier Proteins; Cattle; Centrifugation, Density Gradient; CHO Cells; Cholera Toxin; Cricetinae; Cyclopentanes; Dimyristoylphosphatidylcholine; Endopeptidases; Endoplasmic Reticulum; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Liver; Molecular Sequence Data; Myristic Acid; Myristic Acids; NAD; Peptides; Rats; Recombinant Proteins | 1993 |
Effects of brefeldin A and accessory proteins on association of ADP-ribosylation factors 1, 3, and 5 with Golgi.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brain; Brefeldin A; Carrier Proteins; Chromatography, Ion Exchange; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Nerve Tissue Proteins; Rats | 1993 |
Cytoplasmic coat proteins involved in endosome function.
Topics: ADP-Ribosylation Factors; Animals; Biological Transport; Brefeldin A; Cell Fractionation; Chlorocebus aethiops; CHO Cells; Clathrin; Coated Pits, Cell-Membrane; Coatomer Protein; Cricetinae; Cyclopentanes; Endosomes; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Horseradish Peroxidase; Humans; Intracellular Membranes; Membrane Glycoproteins; Membrane Proteins; Microtubule-Associated Proteins; Transferrin; Vero Cells; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1995 |
Myristoylation-facilitated binding of the G protein ARF1GDP to membrane phospholipids is required for its activation by a soluble nucleotide exchange factor.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brefeldin A; Carrier Proteins; Cattle; Cell Membrane; Cyclopentanes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Liposomes; Magnesium; Membrane Lipids; Myristic Acid; Myristic Acids; Phospholipids; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Recombinant Proteins; Rod Cell Outer Segment; Trypsin | 1996 |
Intracellular distribution of Arf proteins in mammalian cells. Arf6 is uniquely localized to the plasma membrane.
Topics: ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Antibodies; Blotting, Northern; Blotting, Western; Brefeldin A; Carrier Proteins; Cell Membrane; Clathrin; Coatomer Protein; Cricetinae; Cricetulus; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Proteins; Molecular Sequence Data; Sequence Homology, Amino Acid; Substrate Specificity | 1996 |
The mammalian ARF-like protein 1 (Arl1) is associated with the Golgi complex.
Topics: ADP-Ribosylation Factors; Aluminum Compounds; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Blotting, Northern; Brefeldin A; Cell Line; Cell Nucleus; CHO Cells; Cloning, Molecular; Cricetinae; Cyclopentanes; DNA, Complementary; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); L Cells; LLC-PK1 Cells; Mammals; Mice; Molecular Sequence Data; Nocodazole; Rabbits; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Swine | 1996 |
p230 is associated with vesicles budding from the trans-Golgi network.
Topics: Aluminum Compounds; Animals; Autoantibodies; Autoantigens; Brefeldin A; Cell Line; Cyclopentanes; Dogs; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Membrane Proteins; Microscopy, Electron | 1996 |
Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Brefeldin A; Cell Adhesion Molecules; Cell Line, Transformed; Cloning, Molecular; Cyclopentanes; Fungal Proteins; Genes, Fungal; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Saccharomyces cerevisiae; Sequence Alignment; Sequence Analysis | 1997 |
ATP-dependent formation of free synaptic vesicles from PC12 membranes in vitro.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Brefeldin A; Cell-Free System; Cyclopentanes; Cytosol; Enzyme-Linked Immunosorbent Assay; Ethylmaleimide; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; PC12 Cells; Protein Synthesis Inhibitors; Rats; Synaptic Vesicles; Temperature | 1997 |
ARF is not required for nuclear vesicle fusion or mitotic membrane disassembly in vitro: evidence for a non-ARF GTPase in fusion.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brefeldin A; Cyclopentanes; Cytosol; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Fusion; Mitosis; Nuclear Envelope; Protein Synthesis Inhibitors; Rats; Xenopus laevis | 1997 |
ARF-independent inhibition of the carbachol-induced contractions by brefeldin A in intestinal smooth muscle.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brefeldin A; Calcium Channel Blockers; Calcium Channels; Carbachol; Cyclopentanes; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Rats; Rats, Wistar | 1997 |
Evidence that a low-molecular-mass GTP-binding protein is required for store-activated Ca2+ inflow in hepatocytes.
Topics: ADP-Ribosylation Factors; Animals; Brefeldin A; Calcium; Cyclopentanes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Ion Transport; Liver; Peptide Fragments; Rats; Thapsigargin; Vasopressins | 1997 |
Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Brefeldin A; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Galactosyltransferases; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA.
Topics: ADP-Ribosylation Factors; Amino Acid Sequence; Brefeldin A; Chemokine CCL5; Cyclopentanes; Drug Synergism; Enzyme Activation; Epoxy Compounds; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Jurkat Cells; Molecular Sequence Data; Phospholipase D; Protein Binding; Protein Kinase C; rhoA GTP-Binding Protein; Spiro Compounds; T-Lymphocytes | 1998 |
Brefeldin A-inhibited guanine nucleotide-exchange activity of Sec7 domain from yeast Sec7 with yeast and mammalian ADP ribosylation factors.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Brefeldin A; Carrier Proteins; Cholera Toxin; Cloning, Molecular; Cyclopentanes; DNA Primers; Fungal Proteins; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; NAD; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Tagged Sites | 1998 |
Activation of phospholipase D by ADP-ribosylation factor in rat submandibular acinar cells.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acids; Brefeldin A; Carbachol; Carrier Proteins; Cyclopentanes; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Macrolides; Male; Membrane Lipids; Phosphatidic Acids; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipase D; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Pyrrolidinones; ras Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Submandibular Gland; Time Factors; Type C Phospholipases | 1998 |
Brefeldin A inhibits cell-free, de novo synthesis of poliovirus.
Topics: ADP-Ribosylation Factors; Animals; Anti-Bacterial Agents; Antiviral Agents; Binding, Competitive; Brefeldin A; Cell-Free System; Cyclopentanes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Macrolides; Mice; Poliovirus; Virus Replication | 1998 |
ADP-Ribosylation factor 1 (ARF1) regulates recruitment of the AP-3 adaptor complex to membranes.
Topics: Adaptor Proteins, Vesicular Transport; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Anti-Bacterial Agents; Brain; Brefeldin A; Cattle; Cells, Cultured; Cyclopentanes; Cytosol; Dogs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HeLa Cells; Humans; In Vitro Techniques; Intracellular Membranes; Macrolides; Microscopy, Fluorescence; Monomeric Clathrin Assembly Proteins; Mutation; Nerve Tissue Proteins; Phosphoproteins; Recombinant Proteins; Signal Transduction | 1998 |
Synthesis and biological activities of conformationally restricted cyclopentenyl-glutamate analogues.
Topics: Animals; Calcium Signaling; CHO Cells; Cricetinae; Cyclopentanes; Glutamates; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Molecular Conformation; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Structure-Activity Relationship; Transfection | 2002 |
N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.
Topics: Allosteric Regulation; Animals; Baclofen; CHO Cells; Cricetinae; Cyclopentanes; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Kinetics; Oocytes; Potassium Channels; Pyrimidines; Radioligand Assay; Signal Transduction; Structure-Activity Relationship; Sulfur Radioisotopes; Xenopus | 2003 |
Fancy bioisosteres: metallocene-derived G-protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles.
Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Cyclopentanes; Ferrous Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Metallocenes; Mitosis; Models, Molecular; Organometallic Compounds; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Receptors, G-Protein-Coupled; Ruthenium; Structure-Activity Relationship | 2005 |
Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model.
Topics: Acoustic Stimulation; Allosteric Regulation; Allosteric Site; Animals; Animals, Newborn; Anticonvulsants; Baclofen; Cyclopentanes; Drug Interactions; GABA Agonists; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred DBA; Morpholines; Motor Activity; Protein Binding; Pyrazoles; Pyrimidines; Seizures; Sulfur Isotopes | 2016 |
Structure optimization of positive allosteric modulators of GABA
Topics: Allosteric Regulation; Baclofen; Benzofurans; Binding Sites; Cyclization; Cyclopentanes; Drug Evaluation, Preclinical; GABA Modulators; GABA-B Receptor Agonists; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Norbornanes; Protein Binding; Pyrimidines; Receptors, GABA-B; Structure-Activity Relationship | 2020 |