cyclopentane has been researched along with bortezomib in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rolfe, M; Smith, PG; Soucy, TA | 1 |
| Harper, JW; Lim, HJ; Tan, MK | 1 |
| Bernal, L; Boise, LH; Chen, J; Gu, Y; Harvey, RD; Kaufman, JL; Lonial, S; Matulis, SM; Sun, SY; Torre, C | 1 |
| Gu, Z; Huang, J; Thomas, GS; Tricot, G; Xu, H; Yang, Y; Zhan, F; Zhou, Y | 1 |
| Anderson, KC; Cang, Y; Hideshima, T; Ho, M; Liu, J; Peng, Z; Song, T; Tai, YT; Wang, S; Xing, L; Zhou, W | 1 |
| Ehrenschwender, M; El-Mesery, M; Leich, E; Rauert-Wunderlich, H; Rosenthal, T; Schlosser, A; Schreder, M; Siegmund, D; Stühmer, T; Wajant, H | 1 |
6 other study(ies) available for cyclopentane and bortezomib
| Article | Year |
|---|---|
Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cullin Proteins; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrimidines; RING Finger Domains; Signal Transduction; Ubiquitin-Activating Enzymes; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitins | 2009 |
SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation.
Topics: Basic Helix-Loop-Helix Transcription Factors; Boronic Acids; Bortezomib; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromatin; Cyclopentanes; Epigenesis, Genetic; F-Box Proteins; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Mass Spectrometry; Methylation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Pyrazines; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Signal Transduction; Ubiquitination | 2011 |
MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Humans; Multiple Myeloma; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Pyrimidines; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Ubiquitin-Activating Enzymes; Up-Regulation | 2014 |
NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
Topics: Antineoplastic Agents; Apoptosis; Bortezomib; CDC2-CDC28 Kinases; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclopentanes; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Multiple Myeloma; NEDD8 Protein; Proteolysis; Pyrimidines; Signal Transduction; Ubiquitins | 2015 |
A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Biomarkers, Tumor; Bortezomib; COP9 Signalosome Complex; CRISPR-Cas Systems; Cyclopentanes; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Ikaros Transcription Factor; Immunologic Factors; Multiple Myeloma; Peptide Hydrolases; Prognosis; Proteolysis; Pyrimidines; Tumor Cells, Cultured; Ubiquitin-Protein Ligases; Ubiquitination | 2019 |
The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1
Topics: Adult; Aged; Apoptosis; Bortezomib; Cell Line, Tumor; Cell Survival; Cyclopentanes; Female; Humans; Male; Middle Aged; Multiple Myeloma; Necrosis; NF-kappa B; Oligopeptides; Pyrimidines; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tumor Necrosis Factor-alpha; Ubiquitin-Activating Enzymes | 2019 |