Page last updated: 2024-08-21

cyclopentane and 3-hydroxycyclopent-1-enecarboxylic acid

cyclopentane has been researched along with 3-hydroxycyclopent-1-enecarboxylic acid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Bay, T; Bundgaard, C; Clausen, RP; Frølund, B; Kehler, J; Marek, A; Pedersen, MH; Vogensen, SB; Wellendorph, P1
Bundgaard, C; Clausen, RP; Frølund, B; Kehler, J; Thiesen, L; Wellendorph, P1
Bay, T; Clausen, RP; Falk-Petersen, CB; Frølund, B; Hansen, HD; Klein, AB; Knudsen, GM; Marek, A; Villumsen, IS; Wellendorph, P1
Bay, T; Bundgaard, C; Clausen, RP; Frølund, B; Hansen, HD; Herth, MM; Jensen, CH; Knudsen, GM; Lehel, S; Thiesen, L; Vogensen, SB; Wellendorph, P1
Bavo, F; Clausen, RP; Falk-Petersen, CB; Frølund, B; Gloriam, DE; Harpsøe, K; Haugaard, AS; Jensen, CH; Kehler, J; Kongstad, KT; Krall, J; Nittegaard-Nielsen, M; Sigurdardóttir, SB; Tian, Y; Vogensen, SB; Wellendorph, P1
Bach, A; Burnie, RO; Chi, CC; Clarkson, AN; Clausen, RP; Frølund, B; Gauger, SJ; Gee, CL; Gowing, EK; Griem-Krey, N; Hamborg, L; Houlton, J; Kelstrup, CD; Kerr, DS; Klein, AB; Kornum, BR; Kuriyan, J; Larsen, ASG; Leurs, U; McSpadden, ED; Olsen, JV; Palmelund, LB; Shehata, MA; Solbak, SMØ; Teurlings, SMW; van Woerden, GM; Villumsen, IS; Vogensen, SB; Wellendorph, P1

Other Studies

6 other study(ies) available for cyclopentane and 3-hydroxycyclopent-1-enecarboxylic acid

ArticleYear
New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Animals; Benzocycloheptenes; Binding Sites; Binding, Competitive; Brain; Carboxylic Acids; Cell Line; Central Nervous System; Cyclopentanes; Drug Stability; gamma-Aminobutyric Acid; Hydroxybutyrates; Kinetics; Ligands; Male; Models, Chemical; Molecular Structure; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Tritium

2013
In Vitro and In Vivo Evidence for Active Brain Uptake of the GHB Analog HOCPCA by the Monocarboxylate Transporter Subtype 1.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 354, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Carboxylic Acids; Cyclopentanes; Dogs; Humans; Madin Darby Canine Kidney Cells; Male; Mice; Monocarboxylic Acid Transporters; Rats; Sodium Oxybate; Symporters; Xenopus laevis

2015
Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using
    Neurochemistry international, 2016, Volume: 100

    Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Carboxylic Acids; Cyclopentanes; Hydroxybutyrates; Mice; Radioligand Assay; Rodentia

2016
Radiosynthesis and Evaluation of [
    ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carbon Isotopes; Carboxylic Acids; Cyclopentanes; Dose-Response Relationship, Drug; Female; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Swine

2017
Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs.
    Journal of medicinal chemistry, 2017, 11-09, Volume: 60, Issue:21

    Topics: Binding Sites; Carboxylic Acids; Crotonates; Cyclopentanes; Drug Design; Hydroxybutyrates; Ligands; Models, Molecular; Molecular Conformation; Structure-Activity Relationship

2017
GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 08-03, Volume: 118, Issue:31

    Topics: Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carboxylic Acids; Crystallography, X-Ray; Cyclopentanes; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Neuroprotection; Protein Binding; Protein Domains; Signal Transduction; Sodium Oxybate

2021