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cyclopentane and 15-deoxy-delta(12,14)-prostaglandin j2

cyclopentane has been researched along with 15-deoxy-delta(12,14)-prostaglandin j2 in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's24 (92.31)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, Y; Kapahi, P; Karin, M; Natoli, G; Rossi, A; Santoro, MG; Takahashi, T1
Ghosh, G; Glass, CK; Hsiang, CH; Li, M; Pascual, G; Ricote, M; Sengchanthalangsy, LL; Straus, DS; Welch, JS1
Alvarez, AM; Boscá, L; Castrillo, A; Hortelano, S1
Dixon, C; Hilbelink, T; Lu, L; Rovin, BH; Wilmer, WA1
Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C1
Britti, D; Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Dugo, L; Mazzon, E; Serraino, I; Thiemermann, C; Wayman, NS1
Bureau, F; Desmet, C; Jaspar, F; Lekeux, P; Mélotte, D; Pastoret, PP; Piette, J; Vanderplasschen, A; Volanti, C1
Cippitelli, M; Di Bona, D; Fionda, C; Frati, L; Lupo, A; Piccoli, M; Santoni, A1
Ishii, T; Kumazawa, S; Masutani, H; Nakamura, H; Shibata, T; Uchida, K; Yamada, T; Yodoi, J1
Di Meglio, P; Di Rosa, M; Ialenti, A; Ianaro, A; Maffia, P; Santoro, MG1
Erl, W; Vosseler, CA; Weber, PC1
Kondo, M; Masutani, H; Nakamura, H; Shibata, T; Tanahashi, N; Tanaka, K; Uchida, K; Yamada, T; Yodoi, J1
Alba, G; Alvarez-Maqueda, M; Bedoya, FJ; Chacón, P; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Pintado, E; Sobrino, F; Vega, A1
Baud, L; Bellocq, A; Cheron, A; Fouqueray, B; Peltier, J; Perez, J1
Nikitakis, NG; Sauk, JJ; Siavash, H1
Cernuda-Morollón, E; Pérez-Sala, D; Sánchez-Gómez, FJ; Stamatakis, K1
Masuko-Hongo, K1
Gayarre, J; Pérez-Sala, D; Renedo, M; Stamatakis, K1
Albicini, M; Asfar, P; Bauer, M; Bracht, H; Brückner, UB; Ehrmann, U; Hauser, B; Iványi, Z; Kick, J; Muth, CM; Radermacher, P; Vogt, J; Wachter, U1
Avellano, MI; Gayarre, J; Pérez-Sala, D; Sánchez-Gómez, FJ1
Blay, J; Lowthers, EL; Richard, CL1
Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Genovese, T; Mazzon, E; Meli, R; Muià, C1
Bennett, PR; Lindström, TM; Mehmet, H; Pirianov, G; Terzidou, V; Waddington, SN1
Kim, DH; Kim, EH; Na, HK; Surh, YJ1
Hayakari, M; Mori, F; Shibata, T; Tanji, K; Uchida, K; Wakabayashi, K; Yoshida, H; Zhang, HX1
Freeman, BA; Iwamoto, N; Kawakami, K; Kobayashi, M; Kumagai, Y; Li, L; Nakajima, H; Nakajima-Takagi, Y; Ohashi, K; Tsujita, T; Yamamoto, M1

Reviews

1 review(s) available for cyclopentane and 15-deoxy-delta(12,14)-prostaglandin j2

ArticleYear
[Role of prostaglandins in rheumatoid arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Animals; Apoptosis; Arthritis, Rheumatoid; Cartilage, Articular; Cyclopentanes; Dinoprostone; Humans; Inflammation Mediators; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Synovial Membrane

2005

Other Studies

25 other study(ies) available for cyclopentane and 15-deoxy-delta(12,14)-prostaglandin j2

ArticleYear
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase.
    Nature, 2000, Jan-06, Volume: 403, Issue:6765

    Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; COS Cells; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; I-kappa B Kinase; Jurkat Cells; Molecular Sequence Data; NF-kappa B; Prostaglandin D2; Prostaglandins A; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2000
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Apr-25, Volume: 97, Issue:9

    Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclopentanes; Glutathione Transferase; HeLa Cells; Humans; Isoenzymes; Membrane Proteins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins A; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection

2000
Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Dec-01, Volume: 165, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cell Line; Cyclopentanes; Drug Synergism; Inflammation Mediators; Macrophage Activation; Macrophages; MAP Kinase Signaling System; Mice; Microbodies; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Superoxides; Transcription Factors

2000
A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
    Biochemical and biophysical research communications, 2001, Feb-16, Volume: 281, Issue:1

    Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glomerular Mesangium; Humans; Hypoglycemic Agents; Immunologic Factors; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors

2001
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:4

    Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha

2001
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Arthritis, Experimental; Carrageenan; Cyclopentanes; Disease Models, Animal; Immunohistochemistry; Immunologic Factors; Inflammation; Male; Mice; Mice, Inbred BALB C; Pleurisy; Prostaglandin D2

2002
A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition.
    Journal of immunology (Baltimore, Md. : 1950), 2002, May-15, Volume: 168, Issue:10

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cyclopentanes; Cytokines; Dose-Response Relationship, Immunologic; Enzyme Activation; HeLa Cells; Humans; Inflammation Mediators; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Prostaglandin D2; Prostaglandins; Prostaglandins A; Protein Processing, Post-Translational; Reactive Oxygen Species; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells

2002
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms.
    Journal of immunology (Baltimore, Md. : 1950), 2003, May-01, Volume: 170, Issue:9

    Topics: Animals; Apoptosis; Cell Line, Transformed; Cyclopentanes; DNA-Binding Proteins; Early Growth Response Protein 1; Fas Ligand Protein; fas Receptor; Gene Silencing; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Humans; Hybridomas; Immediate-Early Proteins; Jurkat Cells; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Mice; Peroxisomes; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Transcription Factors

2003
Thioredoxin as a molecular target of cyclopentenone prostaglandins.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Amino Acid Sequence; Biotinylation; Cell Death; Cyclopentanes; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunoblotting; Models, Chemical; Molecular Sequence Data; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Peptides; Prostaglandin D2; Prostaglandins; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxins; Transfection; Tumor Cells, Cultured

2003
Anti-inflammatory activity of 15-deoxy-delta12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response.
    Molecular pharmacology, 2003, Volume: 64, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclopentanes; DNA-Binding Proteins; Edema; Heat Shock Transcription Factors; Heat-Shock Proteins; Heat-Shock Response; HSP72 Heat-Shock Proteins; Male; Prostaglandin D2; Rats; Rats, Wistar; Time Factors; Transcription Factors

2003
Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis.
    Biochemical and biophysical research communications, 2003, Jul-25, Volume: 307, Issue:2

    Topics: Apoptosis; Cell Line; Cyclopentanes; Endothelium, Vascular; Humans; Molecular Structure; Prostaglandin D2; Prostaglandins

2003
An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome.
    Biochemistry, 2003, Dec-02, Volume: 42, Issue:47

    Topics: Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cyclopentanes; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Immunologic Factors; Membrane Proteins; Multienzyme Complexes; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Proteins; Rats; Structure-Activity Relationship; Thioredoxins; Transfection; Tumor Suppressor Protein p53

2003
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Acetylcysteine; Allopurinol; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cyclic N-Oxides; Cyclopentanes; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ions; Lymphocytes; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenanthrolines; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Temperature; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Xanthine Oxidase

2004
15-deoxy-Delta12,14-prostaglandin J2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor gamma-independent process.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Jun-15, Volume: 172, Issue:12

    Topics: Animals; Cell Line; Chemokine CCL2; Cyclopentanes; Dexamethasone; Glucocorticoids; Humans; Macrophages; Mice; Monocytes; Prostaglandin D2; Radioligand Assay; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Signal Transduction; Transcription Factors; Transcription, Genetic; U937 Cells

2004
Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells.
    Cancer letters, 2004, Jul-28, Volume: 211, Issue:1

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclopentanes; ErbB Receptors; Humans; Mouth Neoplasms; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2004
Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.
    Molecular pharmacology, 2004, Volume: 66, Issue:5

    Topics: Animals; Biotinylation; Cell Nucleus; Cells, Cultured; Cyclooxygenase 2; Cyclopentanes; Cytosol; Gene Silencing; Glomerular Mesangium; Inflammation; Intercellular Adhesion Molecule-1; Isoenzymes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisome Proliferator-Activated Receptors; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Proteins; Rats; Sulfhydryl Compounds; Transfection

2004
Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione.
    FEBS letters, 2005, Oct-24, Volume: 579, Issue:25

    Topics: Animals; Cyclopentanes; Glutathione; Mice; NIH 3T3 Cells; Prostaglandin D2; Prostaglandins A; Proteins

2005
Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia.
    Intensive care medicine, 2006, Volume: 32, Issue:5

    Topics: Animals; Cyclopentanes; Endotoxemia; Europe; Hypotension; Immunologic Factors; Oxidative Stress; Prospective Studies; Prostaglandin D2; Prostaglandins; Random Allocation; Respiration, Artificial; Swine

2006
Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival.
    Archives of biochemistry and biophysics, 2007, Jan-15, Volume: 457, Issue:2

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cyclopentanes; Enzyme Activation; Glutathione S-Transferase pi; Humans; Mice; Molecular Sequence Data; Prostaglandin D2; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2007
15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways.
    Experimental cell research, 2007, Oct-01, Volume: 313, Issue:16

    Topics: Animals; Carcinoma; Cell Line, Tumor; Cyclopentanes; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; NF-kappa B; PPAR gamma; Prostaglandin D2; Receptors, CXCR4; Rosiglitazone; Thiazolidinediones; Time Factors

2007
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury.
    Shock (Augusta, Ga.), 2008, Volume: 30, Issue:2

    Topics: Animals; Cyclization; Cyclopentanes; Disease Models, Animal; Inflammation Mediators; Ligands; Male; Mice; Mice, Inbred Strains; Neutrophil Infiltration; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Prostaglandin D2; Random Allocation; Recovery of Function; Severity of Illness Index; Spinal Cord Injuries

2008
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse.
    Endocrinology, 2009, Volume: 150, Issue:2

    Topics: Animals; Animals, Newborn; Animals, Outbred Strains; Anti-Inflammatory Agents; Cyclopentanes; Drug Evaluation, Preclinical; Female; Inflammation; Lipopolysaccharides; Mice; Myometrium; NF-kappa B; Obstetric Labor, Premature; Phospholipases A2; Phosphorylation; Pregnancy; Prostaglandin D2; Time Factors; Uterine Diseases; Uterus

2009
Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell-Free System; Cyclopentanes; Cytosol; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Female; Humans; Immunohistochemistry; Microscopy, Confocal; Molecular Structure; Prostaglandin D2; Prostaglandins A; Protein Binding; Time Factors; Tumor Suppressor Protein p53

2009
Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2).
    Experimental neurology, 2010, Volume: 222, Issue:2

    Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Cell Line; Cyclopentanes; Cytoplasm; DNA-Binding Proteins; Female; Gene Expression Regulation; Humans; Immunologic Factors; Male; Middle Aged; Neuroblastoma; Prostaglandin D2; Spinal Cord; Subcellular Fractions

2010
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish.
    Genes to cells : devoted to molecular & cellular mechanisms, 2011, Volume: 16, Issue:1

    Topics: Animals; Animals, Genetically Modified; Carrier Proteins; Cell Line; Cells, Cultured; Cyclopentanes; Cysteine; Fatty Acids; Green Fluorescent Proteins; Hydrogen Peroxide; NF-E2-Related Factor 2; Oleic Acids; Oxidative Stress; Prostaglandin D2; Prostaglandins; Trans-Activators; Zebrafish; Zebrafish Proteins

2011