cyclohexylaminoglutethimide has been researched along with aminoglutethimide in 4 studies
*Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER. [MeSH]
*Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER. [MeSH]
| Studies (cyclohexylaminoglutethimide) | Trials (cyclohexylaminoglutethimide) | Recent Studies (post-2010) (cyclohexylaminoglutethimide) | Studies (aminoglutethimide) | Trials (aminoglutethimide) | Recent Studies (post-2010) (aminoglutethimide) |
|---|---|---|---|---|---|
| 8 | 0 | 2 | 1,489 | 135 | 56 |
| Protein | Taxonomy | cyclohexylaminoglutethimide (IC50) | aminoglutethimide (IC50) |
|---|---|---|---|
| Aromatase | Homo sapiens (human) | 5.043 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 0.27 | |
| Aromatase | Rattus norvegicus (Norway rat) | 6.2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.27 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batzl, C; Hartmann, RW; Mannschreck, A; Pongratz, TM | 1 |
| Bartz, U; Grün, G; Hartmann, RW; Palzer, M | 1 |
| Aboul-Enein, HY; Ogbunude, PO | 1 |
| Aboui-Enein, HY; Aboul-Enein, HY; Farooqi, ZH | 1 |
4 other study(ies) available for cyclohexylaminoglutethimide and aminoglutethimide
| Article | Year |
|---|---|
Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones.
Topics: Aminoglutethimide; Aromatase Inhibitors; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallization; Female; Humans; Molecular Conformation; Piperidones; Placenta; Stereoisomerism | 1992 |
Evaluation of the racemate and the enantiomers of a new highly active and selective aromatase inhibitor of the aminoglutethimide type.
Topics: Adrenal Glands; Aldosterone; Aminoglutethimide; Animals; Aromatase Inhibitors; Cattle; Corticosterone; Estradiol; Female; Humans; Locomotion; Lyases; Mammary Neoplasms, Experimental; Mice; Piperidones; Placenta; Rats; Stereoisomerism; Tumor Cells, Cultured | 1992 |
In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Female; Glutethimide; In Vitro Techniques; Microsomes; Ovary; Rats; Stereoisomerism | 1994 |
Conformational flexibility of cyclohexylaminoglutethimide: a potent aromatase inhibitor. Comparison of the three configurations of the cyclohexyl moiety.
Topics: Aminoglutethimide; Aromatase Inhibitors; Cyclohexylamines; Glutethimide; Models, Molecular; Protein Conformation | 1994 |