Page last updated: 2024-08-26

cyclohexylalanine and phenylalanine

cyclohexylalanine has been researched along with phenylalanine in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.45)	18.7374
1990's	6 (20.69)	18.2507
2000's	14 (48.28)	29.6817
2010's	6 (20.69)	24.3611
2020's	2 (6.90)	2.80

Authors

Authors	Studies
Burke, GT; Chu, YC; Katsoyannis, PG; Zong, L	1
Cordopatis, P; Franklin, KJ; Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, GJ	1
Aarstad, K; Laland, SG; Zimmer, TL	1
Armstrong, KM; Baldwin, RL; Fairman, R	1
Appleby, SD; Baskin, EP; Chen, IW; Dancheck, KB; Gardell, SJ; Lewis, SD; Lucas, BJ; Lumma, WC; Lyle, EA; Lynch, JJ; Tucker, TJ; Vacca, JP; Woltmann, R	1
De Filippis, V; Di Cera, E; Fontana, A; Quarzago, D; Vindigni, A	1
Batdorsdhjin, M; Greiner, G; Kleinwächter, P; Reissmann, S; Seyfarth, L; Steinmetzer, T; Stürzebecher, J	1
Kennan, AJ; Schnarr, NA	5
Cain, SA; Coughlan, T; Monk, PN	1
Bode, W; Friedrich, R; Huber, R; Steinmetzer, T; Stürzebecher, J	1
Tatko, CD; Waters, ML	2
Angelatou, F; Georgiev, V; Kostopoulos, G; Sotiriou, E; Tchekalarova, J	1
Franzyk, H; Jaroszewski, JW; Mellor, IR; Olsen, CA; Usherwood, PN; Wellendorph, P; Witt, M	1
Ballet, S; Benyhe, S; Borsodi, A; Chung, NN; Ioja, E; Martinek, T; Péter, A; Schiller, PW; Tömböly, C; Tóth, G; Tourwé, D	1
Albasanz, JL; Barrachina, M; Ferrer, I; Martín, M; Perez-Buira, S; Rodriguez, A	1
Choi, DY; Kim, HJ; Kim, JH; Park, HW; Shin, CS; Youn, SH	1
Aldrich, JV; Bennett, MA; Fang, WJ; Murray, TF	1
Chuman, Y; Ishimori, K; Ito, I; Kamada, R; Nomura, T; Sakaguchi, K; Sakamoto, K; Shimohigashi, Y	1
Gao, J; Kim, D; Pace, CJ	1
Rammensee, HG; Ramnarayan, VR; Saini, SK; Schuster, H; Springer, S; Stevanović, S	1
Cotterell, AJ; Fairlie, DP; Lim, J; Liu, L; Lohman, RJ; Reid, RC; Suen, JY; Vesey, DA; Yau, MK	1
Aho, V; Ikonen, HMK; Panula, P; Porkka-Heiskanen, T; Puttonen, HAJ; Salminen, T; Vainikka, M; Wigren, HK	1
Chen, J; Jia, Z; Schmit, JD	1
Guaglianone, GE; Haerianardakani, S; Kreutzer, AG; Nowick, JS; Salveson, PJ; Samdin, TD	1

Other Studies

29 other study(ies) available for cyclohexylalanine and phenylalanine

Article	Year
The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone. Journal of protein chemistry, 1992, Volume: 11, Issue:5 Topics: Adipose Tissue; Alanine; Amino Acids; Animals; Cattle; Cycloleucine; Glucose; Glutamates; Glutamic Acid; Histidine; Insulin; Lipids; Liver; Lysine; Phenylalanine; Rats; Receptor, Insulin; Sheep; Structure-Activity Relationship; Swine; Tyrosine	1992
Synthesis and biological activities of angiotensin II and Sarmesin analogues containing cyclohexylalanine. International journal of peptide and protein research, 1991, Volume: 37, Issue:1 Topics: Angiotensin II; Animals; Female; In Vitro Techniques; Phenylalanine; Rats; Structure-Activity Relationship; Uterine Contraction	1991
The fidelity of gramicidin S synthetase. European journal of biochemistry, 1980, Volume: 112, Issue:2 Topics: Amino Acid Isomerases; Bacillus; Kinetics; Leucine; Multienzyme Complexes; Oligopeptides; Peptide Synthases; Peptides, Cyclic; Phenylalanine; Protein Binding; Substrate Specificity; Valine	1980
The (i, i + 4) Phe-His interaction studied in an alanine-based alpha-helix. Journal of molecular biology, 1993, Mar-05, Volume: 230, Issue:1 Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Peptides; Phenylalanine; Protein Structure, Secondary	1993
Potent noncovalent thrombin inhibitors that utilize the unique amino acid D-dicyclohexylalanine in the P3 position. Implications on oral bioavailability and antithrombotic efficacy. Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11 Topics: Animals; Biological Availability; Dipeptides; Dogs; Fibrinolytic Agents; Lipid Metabolism; Male; Molecular Structure; Partial Thromboplastin Time; Phenylalanine; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thrombin; Thrombosis	1997
Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids. Biochemistry, 1998, Sep-29, Volume: 37, Issue:39 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; Circular Dichroism; Glycine; Hirudins; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Serine; Spectrometry, Fluorescence; Thrombin; Tyrosine; Valine	1998
New thrombin inhibitors based on D-cha-Pro-derivatives. Journal of enzyme inhibition, 1999, Volume: 14, Issue:3 Topics: Agmatine; Anticoagulants; Oligopeptides; Phenols; Phenylalanine; Proline; Serine Proteinase Inhibitors; Thrombin	1999
Coiled-coil formation governed by unnatural hydrophobic core side chains. Journal of the American Chemical Society, 2001, Nov-07, Volume: 123, Issue:44 Topics: Amino Acid Sequence; Circular Dichroism; DNA-Binding Proteins; Fungal Proteins; Molecular Sequence Data; Peptides; Phenylalanine; Protein Conformation; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins	2001
Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor. Biochemistry, 2001, Nov-20, Volume: 40, Issue:46 Topics: Alanine; Animals; Antigens, CD; Arginine; Aspartic Acid; Binding Sites; Cell Culture Techniques; Complement C5a; Complement C5a, des-Arginine; Humans; Iodine Radioisotopes; Ligands; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Radioligand Assay; Rats; Receptor, Anaphylatoxin C5a; Receptors, Complement; Transfection; Tumor Cells, Cultured	2001
The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. Journal of molecular biology, 2002, Mar-01, Volume: 316, Issue:4 Topics: Arginine; Binding Sites; Catalysis; Crystallography, X-Ray; Humans; Kinetics; Models, Molecular; Peptides; Phenylalanine; Protein Conformation; Serine Proteinase Inhibitors; Thrombin	2002
Peptide tic-tac-toe: heterotrimeric coiled-coil specificity from steric matching of multiple hydrophobic side chains. Journal of the American Chemical Society, 2002, Aug-21, Volume: 124, Issue:33 Topics: Alanine; Amino Acid Sequence; Molecular Sequence Data; Peptides; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics	2002
Specific control of peptide assembly with combined hydrophilic and hydrophobic interfaces. Journal of the American Chemical Society, 2003, Jan-22, Volume: 125, Issue:3 Topics: Alanine; Amino Acid Sequence; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Structure, Quaternary; Thermodynamics	2003
Sequential and specific exchange of multiple coiled-coil components. Journal of the American Chemical Society, 2003, Oct-29, Volume: 125, Issue:43 Topics: Alanine; Amino Acid Sequence; Cross-Linking Reagents; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Nitrilotriacetic Acid; Organometallic Compounds; Peptides; Phenylalanine; Protein Structure, Quaternary	2003
Comparison of C-H...pi and hydrophobic interactions in a beta-hairpin peptide: impact on stability and specificity. Journal of the American Chemical Society, 2004, Feb-25, Volume: 126, Issue:7 Topics: Anisotropy; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Lysine; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Protein Conformation; Protein Denaturation; Substrate Specificity; Tryptophan	2004
Investigation of the nature of the methionine-pi interaction in beta-hairpin peptide model systems. Protein science : a publication of the Protein Society, 2004, Volume: 13, Issue:9 Topics: Amides; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Norleucine; Peptides; Phenylalanine; Protein Denaturation; Protein Structure, Secondary; Sulfur; Thermodynamics; Tryptophan	2004
Strand orientation by steric matching: a designed antiparallel coiled-coil trimer. Journal of the American Chemical Society, 2004, Nov-10, Volume: 126, Issue:44 Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Disulfides; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Phenylalanine; Protein Structure, Quaternary; Protein Structure, Secondary; Proteins	2004
Up-regulation of adenosine A1 receptor binding in pentylenetetrazol kindling in mice: effects of angiotensin IV. Brain research, 2005, Jan-25, Volume: 1032, Issue:1-2 Topics: Adenosine A1 Receptor Agonists; Angiotensin II; Animals; Autoradiography; Brain; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Kindling, Neurologic; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Phenylalanine; Protein Binding; Radioligand Assay; Receptor, Adenosine A1; Staining and Labeling; Time Factors	2005
Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers. ChemMedChem, 2006, Volume: 1, Issue:3 Topics: Humans; Ion Channel Gating; Nicotinic Antagonists; Phenylalanine; Polyamines; Receptors, Nicotinic; Wasp Venoms	2006
Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists. Journal of medicinal chemistry, 2007, Jan-25, Volume: 50, Issue:2 Topics: Animals; Binding, Competitive; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Oligopeptides; Phenylalanine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Vas Deferens	2007
Expression levels of adenosine receptors in hippocampus and frontal cortex in argyrophilic grain disease. Neuroscience letters, 2007, Aug-23, Volume: 423, Issue:3 Topics: Adenosine A1 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Cadaver; Cognition Disorders; Colforsin; Dementia; Female; Frontal Lobe; Hippocampus; Humans; Male; Middle Aged; Phenylalanine; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Silver Staining; Tauopathies	2007
Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment. FEMS microbiology letters, 2007, Volume: 276, Issue:1 Topics: Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Inhibitory Concentration 50; Lipase; Monascus; Norleucine; Penicillamine; Phenylalanine; Pigments, Biological	2007
Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity. Biopolymers, 2011, Volume: 96, Issue:1 Topics: Acids; Amino Acid Sequence; Amino Acids; Animals; Binding, Competitive; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Dynorphins; Methylation; Models, Chemical; Molecular Structure; Peptides; Phenylalanine; Protein Binding; Rats; Receptors, Opioid, kappa; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tryptophan; Tyrosine	2011
Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine. Biopolymers, 2011, Volume: 95, Issue:6 Topics: Hydrophobic and Hydrophilic Interactions; Peptides; Phenylalanine; Protein Binding; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Tumor Suppressor Protein p53	2011
Experimental evaluation of CH-π interactions in a protein core. Chemistry (Weinheim an der Bergstrasse, Germany), 2012, May-07, Volume: 18, Issue:19 Topics: Models, Molecular; Phenylalanine; Protein Conformation; Proteins; Thermodynamics; Water	2012
Dipeptides catalyze rapid peptide exchange on MHC class I molecules. Proceedings of the National Academy of Sciences of the United States of America, 2015, Jan-06, Volume: 112, Issue:1 Topics: Amino Acid Sequence; Biocatalysis; Dipeptides; Epitopes; Histocompatibility Antigens Class I; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Phenylalanine; Protein Multimerization	2015
Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Calcium; Cell Line; Edema; HT29 Cells; Humans; Interleukin-6; Isoleucine; Kidney Tubules; Phenylalanine; Rats; Receptor, PAR-2; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2016
Homeostatic response to sleep/rest deprivation by constant water flow in larval zebrafish in both dark and light conditions. Journal of sleep research, 2017, Volume: 26, Issue:3 Topics: Adenosine; Animals; Arousal; Caffeine; Circadian Rhythm; Darkness; Homeostasis; Larva; Light; Models, Animal; Phenylalanine; Receptor, Adenosine A1; Reflex, Startle; Rest; Sleep; Sleep Deprivation; Wakefulness; Water Movements; Zebrafish	2017
Amyloid assembly is dominated by misregistered kinetic traps on an unbiased energy landscape. Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-12, Volume: 117, Issue:19 Topics: Amyloid; Amyloid beta-Peptides; Computer Simulation; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Peptide Fragments; Phenylalanine; Protein Structure, Secondary; Thermodynamics	2020
Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by β-Hairpins Derived from Aβ. Journal of the American Chemical Society, 2020, 12-09, Volume: 142, Issue:49 Topics: Amino Acid Sequence; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Humans; Mutation; Phenylalanine; Protein Conformation, beta-Strand; Protein Multimerization	2020