cycloheximide has been researched along with wortmannin in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (14.89) | 18.2507 |
| 2000's | 31 (65.96) | 29.6817 |
| 2010's | 9 (19.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kikkawa, U; Konishi, H; Kuroda, S; Matsuzaki, H; Ono, Y; Tanaka, M; Tokunaga, C | 1 |
| Culic, O; Gruwel, ML; Schrader, J | 1 |
| Low, SY; Rennie, MJ; Taylor, PM | 1 |
| Carnero, A; Lacal, JC | 1 |
| Keller, GA; Koller, A; Rangell, LK; Sakai, Y; Subramani, S | 1 |
| Eyers, PA; Hundal, HS; McDowell, HE | 1 |
| Miyake, M; Morita, T; Motoyashiki, T; Ueki, H; Yoshida, A | 1 |
| Austin, C; Shaw, L; Taggart, MJ | 1 |
| Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM | 1 |
| Filippa, N; Giorgetti-Peraldi, S; Miele, C; Rochford, JJ; Van Obberghen, E | 1 |
| Ishigaki, Y; Maquat, LE; Nagy, E; Pal, M | 1 |
| Cuttle, KA; Goldstein, RH; Kuang, PP; Poliks, CF; Ricupero, DA; Rishikof, DC | 1 |
| Fang, Y; Jin, J; Wang, L; Zha, X | 1 |
| Colombo, MI; Munafó, DB | 1 |
| Farber, JL; Karpinich, NO; Rothman, RJ; Russo, MA; Tafani, M | 1 |
| Ball, KL; Dornan, D; Kelleher, M; Pamment, J; Ramsay, E | 1 |
| Bussolati, B; Buttiglieri, S; Camussi, G; Deregibus, MC; Russo, S | 1 |
| Beguinot, F; Cassese, A; Condorelli, G; Formisano, P; Giacco, F; Miele, C; Oriente, F; Perfetti, A; Santopietro, S; Trencia, A; Vigliotta, G | 1 |
| Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M | 1 |
| Anel, A; Boyer, C; Buferne, M; Martínez-Lorenzo, MJ; Naval, J; Pardo, J; Schmitt-Verhulst, AM | 1 |
| Casalini, P; Casati, B; Galmozzi, E; Iorio, MV; Ménard, S; Olgiati, C | 1 |
| Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G | 1 |
| Sullivan, CV; Weber, GM | 1 |
| Arbel-Goren, R; Levy, Y; Ronen, D; Zick, Y | 1 |
| Chan, SS; Copeland, WC; Longley, MJ; Naviaux, RK | 1 |
| Bhattacharyya, SP; Mukherjee, D; Paul, S; Sen, U | 1 |
| Lee, CH; Lee, GC; Yi, HA | 1 |
| Moore, AB; Sullivan, CV; Weber, GM | 1 |
| Gu, J; Jiang, J; Liu, D; Shen, J; Wei, Y; Zhou, J; Zhou, L | 1 |
| Ganapathy, V; Kashiwagi, H; Sugawara, M; Takekuma, Y; Yamazaki, K | 1 |
| Holliday, LS; Kohno, S; Vergara, S; Zuo, J | 1 |
| Friedman, JM; McGraw, TE; Rodeheffer, MS; Zeigerer, A | 1 |
| Hirata, H; Inagaki, H; Iwashita, K; Kamata, H; Kawauchi, K; Morikawa, T; Moriyama, Y; Shibukawa, Y; Tobiume, K | 1 |
| Cohen, IS; Doronin, SV; Potapova, IA | 1 |
| Brighente, IM; Cazarolli, LH; Folador, P; Moresco, HH; Pizzolatti, MG; Silva, FR | 1 |
| Horiuchi, N; Maeda, T | 1 |
| Carraro-Lacroix, LR; Girardi, AC; Malnic, G | 1 |
| Cho, EA; Juhnn, YS; Kim, SH; Kim, WH; Oh, JM; Song, YS | 1 |
| Jaiswal, N; Maurya, R; Srivastava, AK; Tamrakar, AK; Yadav, PP | 2 |
| Futahashi, Y; Ichikawa, R; Komano, J; Miyauchi, K; Urano, E | 1 |
| Ishigaki, Y; Matsunaga, T; Nakagawa, H; Nogawa, A; Takegami, T; Zhao, X | 1 |
| Collins, CA; Heese, A; Leslie, ME; Salamango, DJ; Smith, JM | 1 |
| Baltierra-Uribe, SL; Castrejón-Jiménez, NS; Estrella-Piñón, MP; García-Pérez, BE; García-Vásquez, Mde J; Luna-Herrera, J | 1 |
| Appella, E; Fujita, K; Harris, CC; Hiyoshi, Y; Horikawa, I; Jenkins, LM; Lane, DP; Mondal, AM; Vojtesek, B | 1 |
47 other study(ies) available for cycloheximide and wortmannin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.
Topics: 3T3 Cells; Androstadienes; Animals; Anisomycin; Blood Proteins; Cell Line; Chlorocebus aethiops; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Hot Temperature; Isoenzymes; Mice; Oligopeptides; Osmolar Concentration; Peptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Sequence Tagged Sites; Sorbitol; Stress, Physiological; Transfection; Wortmannin | 1996 |
Energy turnover of vascular endothelial cells.
Topics: Actins; Adenosine Triphosphatases; Adenosine Triphosphate; Androstadienes; Animals; Antimycin A; Aorta; Cells, Cultured; Cycloheximide; Cytochalasin D; Deoxyglucose; Diacetyl; Endothelium, Vascular; Energy Metabolism; Enzyme Inhibitors; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Phosphorus; Swine; Thapsigargin; Wortmannin | 1997 |
Signaling elements involved in amino acid transport responses to altered muscle cell volume.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Androstadienes; Animals; Animals, Newborn; Carrier Proteins; Cells, Cultured; Cholera Toxin; Culture Media, Conditioned; Cycloheximide; Enzyme Inhibitors; Glutamine; GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Kinetics; Lysophospholipids; Models, Biological; Muscle, Skeletal; Osmolar Concentration; Peptides; Phosphatidylinositol 3-Kinases; Polyenes; Protein Kinase Inhibitors; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Sodium Chloride; Virulence Factors, Bordetella; Wortmannin | 1997 |
Wortmannin, an inhibitor of phosphatidyl-inositol 3-kinase, induces oocyte maturation through a MPF-MAPK-dependent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Maturation-Promoting Factor; Morpholines; Oocytes; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Wortmannin; Xenopus laevis | 1998 |
Peroxisome degradation by microautophagy in Pichia pastoris: identification of specific steps and morphological intermediates.
Topics: Adaptation, Physiological; Androstadienes; Autophagy; Cycloheximide; Ethanol; Fluorescent Dyes; Green Fluorescent Proteins; Intracellular Membranes; Kinetics; Luminescent Proteins; Microbodies; Peptide Fragments; Phenylmethylsulfonyl Fluoride; Pichia; Protease Inhibitors; Protein Synthesis Inhibitors; Pyridinium Compounds; Quaternary Ammonium Compounds; Staining and Labeling; Vacuoles; Wortmannin | 1998 |
Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress.
Topics: Amino Acids; Androstadienes; Animals; Arsenites; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cycloheximide; Enzyme Inhibitors; Flavonoids; Hot Temperature; Insulin; Kinetics; Muscle, Skeletal; Phosphoinositide-3 Kinase Inhibitors; Rats; Signal Transduction; Sirolimus; Sodium Compounds; Wortmannin | 1998 |
A vanadyl sulfate-bovine serum albumin complex stimulates the release of lipoprotein lipase activity from isolated rat fat pads through an increase in the cellular content of cAMP and myo-inositol 1,4,5-trisphosphate.
Topics: Adipose Tissue; Androstadienes; Animals; Cyclic AMP; Cycloheximide; Enzyme Activation; Genistein; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Male; Rats; Rats, Wistar; Serum Albumin, Bovine; Vanadium Compounds; Wortmannin | 1999 |
Mechanisms of 17 beta-oestradiol induced vasodilatation in isolated pressurized rat small arteries.
Topics: Androstadienes; Animals; Coronary Vessels; Cycloheximide; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Fulvestrant; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pressure; Protein Synthesis Inhibitors; Rats; Rats, Inbred WKY; Receptors, Estrogen; Vasodilation; Wortmannin | 2000 |
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin | 2000 |
Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.
Topics: 3T3 Cells; Androstadienes; Animals; Cycloheximide; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; Lymphokines; Mice; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Proteins; RNA, Messenger; Signal Transduction; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin | 2000 |
Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway.
Topics: Androstadienes; Cell Line; Cycloheximide; HeLa Cells; Humans; Kidney; Kinetics; Phosphatidylinositol 3-Kinases; Phosphorylation; Polyribosomes; Recombinant Proteins; RNA Helicases; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus; Subcellular Fractions; Trans-Activators; Transfection; Wortmannin | 2001 |
Phosphatidylinositol 3-kinase-dependent stabilization of alpha1(I) collagen mRNA in human lung fibroblasts.
Topics: 3T3 Cells; Androstadienes; Animals; Blotting, Northern; Cells, Cultured; Chromones; Collagen; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Kinetics; Lung; Mice; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA Stability; RNA, Messenger; Transfection; Wortmannin | 2001 |
Focal adhesion kinase affects the sensitivity of human hepatocellular carcinoma cell line SMMC-7721 to tumor necrosis factor-alpha/cycloheximide-induced apoptosis by regulating protein kinase B levels.
Topics: Androstadienes; Apoptosis; Carcinoma, Hepatocellular; Cycloheximide; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver Neoplasms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin | 2001 |
A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation.
Topics: Adenine; Amino Acids; Androstadienes; Animals; Autophagy; Cadaverine; CHO Cells; Cricetinae; Cycloheximide; Enzyme Inhibitors; Ethylmaleimide; Fluorescent Dyes; Phagosomes; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Vacuoles; Vinblastine; Wortmannin | 2001 |
The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c.
Topics: Androstadienes; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Line; Cell Survival; Cells, Cultured; Chloride Channels; Cycloheximide; Cytochrome c Group; Cytosol; Diuretics; DNA Damage; Enzyme Inhibitors; Etoposide; Fibroblasts; Furosemide; Mice; Mitochondria; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Synthesis Inhibitors; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Time Factors; Transfection; Tumor Suppressor Protein p53; Ubiquinone; Up-Regulation; Wortmannin | 2002 |
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
Topics: Androstadienes; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Fibroblasts; Gamma Rays; Genes, p53; Genes, Reporter; Humans; Interferon Regulatory Factor-1; Melanoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Poly I-C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin | 2002 |
CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis.
Topics: Androstadienes; Apoptosis; Blotting, Western; Bromodeoxyuridine; CD40 Antigens; CD40 Ligand; Cell Division; Cell Movement; Cell Survival; Cells, Cultured; Chromones; Cycloheximide; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Inhibitors; Flow Cytometry; Humans; Morpholines; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Signal Transduction; Time Factors; TNF Receptor-Associated Factor 6; Transfection; Ubiquitin-Protein Ligases; Wortmannin | 2003 |
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action.
Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; Binding Sites; Blotting, Western; Cell Line; Cycloheximide; DNA, Complementary; Enzyme Inhibitors; Glioma; Glutathione Transferase; Humans; Intracellular Signaling Peptides and Proteins; Mutation; Peptides; Phosphoproteins; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Wortmannin | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cycloheximide; Cytosol; Endosomes; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Liver Neoplasms; Metabolism; Molecular Sequence Data; Nocodazole; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; Time Factors; Wortmannin | 2003 |
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin | 2003 |
HER2 signaling enhances 5'UTR-mediated translation of c-Myc mRNA.
Topics: 5' Untranslated Regions; Androstadienes; Carcinoma; Cell Line, Tumor; Clone Cells; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, myc; Genes, Reporter; Humans; Luciferases; Neuregulin-1; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin | 2004 |
Insulin-like growth factor-I induces oocyte maturational competence but not meiotic resumption in white bass (Morone chrysops) follicles in vitro: evidence for rapid evolution of insulin-like growth factor action.
Topics: 1-Octanol; Androstadienes; Animals; Bass; Chromones; Cortodoxone; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gap Junctions; Heptanol; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Meiosis; Morpholines; Oocytes; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Wortmannin | 2005 |
Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8.
Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Blotting, Northern; Blotting, Western; Bromodeoxyuridine; Cell Adhesion; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cyclin-Dependent Kinase Inhibitor p21; Cycloheximide; DNA; Galectins; Green Fluorescent Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thymidine; Time Factors; Up-Regulation; Wortmannin | 2005 |
Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome.
Topics: Alleles; Alternative Splicing; Amino Acid Sequence; Androstadienes; Caffeine; Child, Preschool; Codon, Nonsense; Codon, Terminator; Cycloheximide; Diffuse Cerebral Sclerosis of Schilder; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Complementary; Exons; Humans; Molecular Sequence Data; RNA, Messenger; Sequence Analysis, DNA; Wortmannin | 2005 |
In vitro effects of insulin-like growth factors and insulin on oocyte maturation and maturation-inducing steroid production in ovarian follicles of common carp, Cyprinus carpio.
Topics: Androstadienes; Animals; Carps; Cattle; Chorionic Gonadotropin; Chromones; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Insulin; Morpholines; Oocytes; Ovarian Follicle; Somatomedins; Species Specificity; Steroids; Time Factors; Wortmannin | 2006 |
Stimulation of interferon-beta gene expression by human cytomegalovirus via nuclear factor kappa B and phosphatidylinositol 3-kinase pathway.
Topics: Androstadienes; Cell Line; Cycloheximide; Cytomegalovirus; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Interferon-beta; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Thiocarbamates; Transcription, Genetic; Wortmannin | 2006 |
In vitro actions of insulin-like growth factor-I on ovarian follicle maturation in white perch (Morone americana).
Topics: Androstadienes; Animals; Bass; Chromones; Cycloheximide; Dactinomycin; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Morpholines; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Sexual Maturation; Steroids; Wortmannin | 2007 |
Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis.
Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromones; Cycloheximide; Drug Evaluation, Preclinical; Drug Synergism; Galactosyltransferases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Morpholines; Phosphatidylinositol 3-Kinases; Substrate Specificity; Up-Regulation; Wortmannin | 2007 |
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Topics: Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acids; Androstadienes; Animals; Anthracenes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Flavonoids; Insulin; Insulin Antagonists; Muscle, Skeletal; Osmotic Pressure; Protein Synthesis Inhibitors; Rats; Up-Regulation; Wortmannin | 2009 |
Biochemical and functional characterization of the actin-binding activity of the B subunit of yeast vacuolar H+-ATPase.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphatases; Amino Acid Motifs; Amino Acid Sequence; Androstadienes; Animals; Cycloheximide; Hydrogen-Ion Concentration; Macrolides; Molecular Sequence Data; Mutation; Profilins; Protein Binding; Protein Subunits; Rabbits; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vacuolar Proton-Translocating ATPases; Wortmannin | 2008 |
Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism.
Topics: 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Brefeldin A; Cell Differentiation; Culture Media; Cycloheximide; Glucose; Insulin; Leptin; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PPAR gamma; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Wortmannin | 2008 |
Cycloprodigiosin hydrochloride activates the Ras-PI3K-Akt pathway and suppresses protein synthesis inhibition-induced apoptosis in PC12 cells.
Topics: Androstadienes; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cycloheximide; Cytoprotection; Dactinomycin; Indoles; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; ras Proteins; Rats; Signal Transduction; Wortmannin | 2008 |
Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.
Topics: Androstadienes; Animals; Antigens, Surface; Apoptosis; Cell Adhesion; Cells, Cultured; Cycloheximide; Endothelial Cells; Enzyme Inhibitors; Humans; Interleukin-1beta; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; NADH Dehydrogenase; Okadaic Acid; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha; von Willebrand Factor; Wortmannin | 2009 |
Mechanism of action of the stimulatory effect of apigenin-6-C-(2''-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake.
Topics: Alloxan; Androstadienes; Animals; Biological Transport; Blood Glucose; Carbon Radioisotopes; Colchicine; Cycloheximide; Diabetes Mellitus, Experimental; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Flavones; Flavonoids; Glucose; Hyperglycemia; Indoles; Insulin; Insulin Secretion; Magnoliopsida; Male; Muscle, Skeletal; Plant Leaves; Rats; Rats, Wistar; Tissue Distribution; Wortmannin | 2009 |
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin | 2009 |
Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.
Topics: Ammonium Chloride; Androstadienes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Buffers; Cell Line, Transformed; Cell Membrane; Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression; Genistein; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Losartan; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Protein-Tyrosine Kinases; Pyridines; Rats; Time Factors; Up-Regulation; Vacuolar Proton-Translocating ATPases; Wortmannin | 2009 |
Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells.
Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Biphenyl Compounds; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Hydrogen Peroxide; Isoquinolines; Neoplasm Proteins; Oncogene Proteins, Viral; Proteasome Endopeptidase Complex; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering; Sulfonamides; Ubiquitin; Uterine Cervical Neoplasms; Wortmannin; Xanthones | 2010 |
Pongamol from Pongamia pinnata stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells.
Topics: Androstadienes; Animals; Benzofurans; Cell Line; Cell Membrane; Cycloheximide; Fruit; Glucose; Glucose Transporter Type 4; Insulin; Millettia; Muscle Fibers, Skeletal; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Plant Extracts; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Transcription, Genetic; Wortmannin | 2011 |
Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner.
Topics: AMP-Activated Protein Kinases; Androstadienes; Animals; Benzopyrans; Cell Membrane; Cycloheximide; Deoxyglucose; Enzyme Activation; Gene Expression Regulation; Glucose Transporter Type 4; Insulin; Millettia; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Transport; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Wortmannin | 2011 |
Regulation of cyclin T1 expression and function by an alternative splice variant that skips exon 7 and contains a premature termination codon.
Topics: Alternative Splicing; Androstadienes; Cell Line; Codon, Terminator; Cyclin T; Cyclin-Dependent Kinase 9; Cycloheximide; Exons; Female; HIV Long Terminal Repeat; HIV-1; Humans; Leukocytes, Mononuclear; Male; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; tat Gene Products, Human Immunodeficiency Virus; Wortmannin | 2012 |
Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.
Topics: Acetylcysteine; Androstadienes; Cycloheximide; Exons; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Nonsense Mediated mRNA Decay; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteasome Inhibitors; Protein Serine-Threonine Kinases; RNA Helicases; RNA-Binding Proteins; RNA, Small Interfering; Trans-Activators; Transcription Factors; Ubiquitin; Wortmannin | 2014 |
Sensitivity to Flg22 is modulated by ligand-induced degradation and de novo synthesis of the endogenous flagellin-receptor FLAGELLIN-SENSING2.
Topics: Androstadienes; Arabidopsis; Arabidopsis Proteins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Flagellin; Ligands; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Signal Transduction; Time Factors; Tyrphostins; Wortmannin | 2014 |
Mycobacteria entry and trafficking into endothelial cells.
Topics: Amiloride; Androstadienes; Anti-Bacterial Agents; Biological Transport; Cells, Cultured; Cycloheximide; Cytochalasin D; Endosomes; Host-Pathogen Interactions; Human Umbilical Vein Endothelial Cells; Humans; Microbial Viability; Microscopy, Confocal; Mycobacterium; Nocodazole; Phagosomes; Vacuoles; Wortmannin | 2014 |
Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cells, Cultured; Cellular Senescence; Cycloheximide; Fibroblasts; Gene Knockdown Techniques; Humans; Membrane Proteins; Microtubule-Associated Proteins; Protein Isoforms; RNA, Small Interfering; Sequestosome-1 Protein; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Wortmannin | 2014 |