cycloheximide and u 0126

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Butadienes; Carbazoles; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; DNA Fragmentation; Drug Synergism; Embryo, Mammalian; Enzyme Inhibitors; Female; Imidazoles; Immunoglobulin G; Indole Alkaloids; Kinetics; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nitric Oxide Donors; Nitriles; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Signal Transduction

Topics: Butadienes; CD36 Antigens; Chromones; Cycloheximide; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoietin; Flavonoids; Gene Expression Regulation; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured

Topics: Anisomycin; Blotting, Northern; Blotting, Western; Butadienes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Ionophores; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha

Topics: Aggrecans; Animals; Butadienes; Cell Differentiation; Cell Line; Cell Nucleus; Chondrocytes; Cycloheximide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Gene Expression Regulation, Enzymologic; Genes, Dominant; Imidazoles; Immunoblotting; Lectins, C-Type; Luciferases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Proteoglycans; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Thiazoles; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta

Topics: Animals; Biological Clocks; Bucladesine; Butadienes; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Circadian Rhythm; Cyclic AMP Response Element-Binding Protein; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation; Imidazoles; In Situ Hybridization; Male; Mice; Neurons; Neuropeptides; Neurotransmitter Agents; Nifedipine; Nitriles; Nuclear Proteins; Period Circadian Proteins; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Chloride; Pregnancy; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors; Transcriptional Activation

Topics: Animals; Antineoplastic Agents, Phytogenic; Bucladesine; Butadienes; Calcium; Chloride-Bicarbonate Antiporters; Cycloheximide; Demecolcine; Enzyme Inhibitors; Female; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Maturation-Promoting Factor; Meiosis; Mice; Nitriles; Okadaic Acid; Oocytes; Pregnancy; Strontium

Topics: Analysis of Variance; Butadienes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Culture Techniques; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Kinase 2; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Periodontal Ligament; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proteoglycans; RNA, Messenger; Thymidine; Time Factors; Up-Regulation

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Butadienes; Carrier Proteins; Cell Line; Chromones; Cricetinae; Cricetulus; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; JNK Mitogen-Activated Protein Kinases; Lung; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction

Topics: Adrenal Glands; Animals; Butadienes; Cations; Cattle; Cells, Cultured; Chromaffin Cells; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Subunits; Protein Synthesis Inhibitors; Receptors, Nicotinic; RNA Stability; RNA, Messenger; Saxitoxin; Sodium; Sodium Channels; Time Factors; Tritium; Up-Regulation

Topics: 3T3 Cells; Animals; Biological Transport; Butadienes; Cycloheximide; Dactinomycin; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kinetics; Mice; Naphthalenes; Nitriles; Osteoblasts; Phosphates; Protein Kinase C; Sodium; Time Factors

Topics: Animals; Blotting, Western; Butadienes; Cells, Cultured; Cycloheximide; Enzyme Activation; Female; MAP Kinase Signaling System; Maturation-Promoting Factor; Meiosis; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oocytes; Oogenesis; Swine

Topics: Adenosine Monophosphate; Amino Acid Transport System X-AG; Amyloid beta-Peptides; Animals; Animals, Newborn; Antioxidants; Astrocytes; Blotting, Western; Butadienes; Cells, Cultured; Cerebral Cortex; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extracellular Space; Flavonoids; Glutamic Acid; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; Rats

Topics: Animals; Butadienes; Cattle; Cell Fusion; Cell Nucleus; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Female; Ionomycin; Maturation-Promoting Factor; Mitogen-Activated Protein Kinases; Mitosis; Nitriles; Oocytes; Parthenogenesis

Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate

Topics: Aldosterone; Animals; Butadienes; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hydrocortisone; Kidney Cortex; Kidney Tubules, Collecting; Mice; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-raf

Topics: Aged; Aged, 80 and over; Aspartic Acid Endopeptidases; Astrocytes; Butadienes; Cell Division; Cell Hypoxia; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Humans; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Nitriles; Oligopeptides; Optic Disk; Protease Inhibitors; Tumor Necrosis Factor-alpha

Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Butadienes; Conditioning, Classical; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fear; Male; MAP Kinase Signaling System; Memory; Nitriles; Rats; Rats, Sprague-Dawley

Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Benzylamines; Butadienes; Calcium Signaling; Carbazoles; Cell Hypoxia; Cell Line; Cycloheximide; Flavonoids; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Ionomycin; Isoquinolines; Kidney; Nitriles; PC12 Cells; Polyribosomes; Protein Biosynthesis; Protein Kinase C-alpha; Protein Kinases; Protein Synthesis Inhibitors; Rats; RNA Caps; RNA, Messenger; RNA, Small Interfering; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases

Topics: 3T3-L1 Cells; Adipocytes; Animals; Blotting, Northern; Blotting, Western; Butadienes; Cycloheximide; Enzyme Inhibitors; Gene Expression; Glucose; Growth Hormone; Insulin; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Time Factors

Topics: Animals; Animals, Newborn; Blotting, Western; Butadienes; Cardiomegaly; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Silencing; Genistein; Imidazoles; Janus Kinases; Myocytes, Cardiac; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Stress, Mechanical

Topics: Apoptosis; Butadienes; Cell Line, Tumor; Cycloheximide; Down-Regulation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; fas Receptor; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 1; Melanoma; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitriles; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Thermodynamics; Up-Regulation

Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Benzhydryl Compounds; Blood Glucose; Butadienes; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Fulvestrant; Half-Life; Leptin; MAP Kinase Kinase 1; Mice; Nitriles; Nucleic Acid Synthesis Inhibitors; Phenols; Phosphorylation; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Resistin; RNA Stability; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation

Topics: Animals; Apoptosis; Butadienes; Caspase 3; Cell Survival; Cells, Cultured; Cycloheximide; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Protein Synthesis Inhibitors; Rats; Sertoli Cells; Transcription Factor AP-1; Transcription, Genetic; Tretinoin; Vitamins

Topics: Adrenergic alpha-Antagonists; Amygdala; Animals; Butadienes; Cycloheximide; Electric Stimulation; Enzyme Inhibitors; Extinction, Psychological; Fear; In Vitro Techniques; Long-Term Synaptic Depression; Male; Microelectrodes; Mitogen-Activated Protein Kinases; Nitriles; Piperidines; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

Topics: 5' Untranslated Regions; Animals; Apoptosis Regulatory Proteins; Base Sequence; Bcl-2-Like Protein 11; Blotting, Western; Butadienes; Cycloheximide; Enzyme Inhibitors; Gene Expression; Luciferases; Membrane Proteins; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Growth Factor; Nitriles; PC12 Cells; Protein Biosynthesis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Rats; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid; Signal Transduction; Time Factors

Topics: alpha-Crystallin B Chain; Bleomycin; Butadienes; Cells, Cultured; Cyclin D1; Cycloheximide; DNA Damage; Etoposide; Humans; Leupeptins; Melanocytes; Melanoma; Mutant Proteins; Mutation; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Tetracycline

Topics: Butadienes; Colon; Cycloheximide; Estradiol; Estrogen Receptor beta; Fulvestrant; Humans; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitriles; Phytoestrogens; Pyridines; Reproducibility of Results; Tissue Survival

Topics: Adenosine Triphosphate; Animals; Butadienes; CD24 Antigen; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cycloheximide; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; HMGB1 Protein; Humans; Inflammation; MAP Kinase Kinase 2; Mice; Mitochondria; NF-kappa B; Nitriles; Pancreatic Neoplasms; Phosphorylation; Protein Binding; Protein Synthesis Inhibitors; Receptor for Advanced Glycation End Products; RNA Interference; RNA, Small Interfering; Rotenone; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Microenvironment; Uncoupling Agents

Topics: Animals; Anthracenes; Base Sequence; Butadienes; Cell Nucleus; Claudin-4; Cycloheximide; Dogs; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Hydrogen Peroxide; Hypertonic Solutions; JNK Mitogen-Activated Protein Kinases; Kidney Tubules, Collecting; Madin Darby Canine Kidney Cells; Models, Biological; Molecular Sequence Data; NADPH Oxidases; Nitriles; Osmolar Concentration; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Sp1 Transcription Factor; Up-Regulation

Topics: Active Transport, Cell Nucleus; Animals; Avoidance Learning; Butadienes; Cell Nucleus; Cycloheximide; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Hot Temperature; Karyopherins; MAP Kinase Signaling System; Memory Consolidation; Memory, Long-Term; Memory, Short-Term; Mifepristone; Mitogen-Activated Protein Kinases; Mushroom Bodies; Neurons; Nitriles; Recombinant Fusion Proteins; Smell; Time Factors

Topics: Antioxidants; Butadienes; Camptothecin; Cell Size; Cellular Senescence; Cycloheximide; DNA Damage; HeLa Cells; Humans; MAP Kinase Signaling System; Nitriles; Protein Biosynthesis; Reactive Oxygen Species; Thymidine

Topics: Animals; Butadienes; Calcium Channels, L-Type; Cells, Cultured; Cycloheximide; Dactinomycin; Guinea Pigs; MAP Kinase Signaling System; Muscle Cells; Muscle, Smooth; Nitriles; Peptides, Cyclic; Trachea; Tumor Necrosis Factor-alpha

Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Butadienes; Cell Survival; Cycloheximide; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; Nitriles; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha