Page last updated: 2024-08-17

cycloheximide and trichostatin a

cycloheximide has been researched along with trichostatin a in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's3 (14.29)18.2507
2000's14 (66.67)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y1
Elagib, KE; Goldfarb, AN; Munson, KM; Peterson, RT; Sweetser, DA; Yeh, JR1
Koizumi, K; Sugita, K; Yoshida, H1
Beppu, T; Nomura, S; Yoshida, M1
Appleton, S; Edmonds, B; James, R; Medina, V; Young, GP; Zalewski, PD1
Faller, DV; Forman, LW; Perrine, SP; Phelan, MW1
Chang, LK; Liu, ST1
Borriello, A; Criniti, V; Della Pietra, V; Della Ragione, F; Indaco, S; Oliva, A; Yamamoto, T; Zappia, V1
Fang, D; Setaluri, V; Tsuji, Y1
Birkeland, M; Chen, Z; Clark, S; Hu, E; Johanson, K; Kirkpatrick, R; Lago, A; Liu, R; Sung, CM; Winkler, JD1
Butler, JE; Fass, DM; Goodman, RH1
Wang, S; Zhu, J1
Kelley, KM; Ratnam, M; Shatnawi, A; Tran, T; Zheng, X1
Alao, JP; Coombes, RC; Gamble, SC; Lam, EW; Pomeranz, KM; Stavropoulou, AV; Vigushin, DM1
Endo, T; Kashima, K; Kume, S; Naito, K; Nishimura, Y; Tojo, H1
Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF1
Bang, YJ; Jong, HS; Jung, Y; Kim, JH; Kim, TY; Lee, JH; Park, JH1
Daigle, D; Gradoville, L; Miller, G; Ye, J1
Beyer, RP; Hallstrand, TS; Kicic, A; Knight, DA; Kobor, MS; Paré, PD; Stevens, PT; Stick, SM; Sutanto, EN; Taplin, C1
Brown, RE; Imran, SA; Wilkinson, DA; Wilkinson, M; Wilkinson, PM1
Du, T; Roizman, B; Zhou, G1

Other Studies

21 other study(ies) available for cycloheximide and trichostatin a

ArticleYear
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.
    Nature chemical biology, 2009, Volume: 5, Issue:4

    Topics: Animals; Animals, Genetically Modified; beta Catenin; Cell Differentiation; Dinoprostone; Gene Expression Regulation; Humans; K562 Cells; Nitrobenzenes; Oncogene Proteins; Small Molecule Libraries; Sulfonamides; Transcription Factors; Zebrafish; Zebrafish Proteins

2009
Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A.
    Cancer research, 1992, Jan-01, Volume: 52, Issue:1

    Topics: 3T3 Cells; Animals; Cell Line, Transformed; Cycloheximide; Hydroxamic Acids; Mice; Oncogenes; Phenotype; RNA, Messenger; Transfection

1992
Effects of trichostatins on differentiation of murine erythroleukemia cells.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Antifungal Agents; Cell Differentiation; Cell Line; Cycloheximide; Dimethyl Sulfoxide; DNA Replication; Friend murine leukemia virus; Glucosides; Hydroxamic Acids; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; RNA; Ultraviolet Rays

1987
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
    Cancer research, 1997, Sep-01, Volume: 57, Issue:17

    Topics: Apoptosis; bcl-2-Associated X Protein; Butyrates; Butyric Acid; Caspase 3; Caspases; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Cytochrome c Group; DNA Fragmentation; DNA, Neoplasm; Enzyme Induction; Histone Deacetylases; Humans; Hydroxamic Acids; Jurkat Cells; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine

1997
Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells.
    The Journal of laboratory and clinical medicine, 1998, Volume: 132, Issue:6

    Topics: Animals; Arginine; Butyrates; Cattle; Cells, Cultured; Cobalt; Cycloheximide; Dactinomycin; Endothelium, Vascular; Gene Expression Regulation; Humans; Hydroxamic Acids; Hypoxia; NG-Nitroarginine Methyl Ester; Oxygen; RNA, Messenger; Thrombospondin 1

1998
Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation.
    Nucleic acids research, 2000, Oct-15, Volume: 28, Issue:20

    Topics: Acetylation; Acetyltransferases; Base Sequence; Binding Sites; Chromatin; Cycloheximide; DNA-Binding Proteins; Drug Synergism; Erythroid-Specific DNA-Binding Factors; Gene Expression Regulation, Viral; Genes, Immediate-Early; Genome, Viral; Herpesvirus 4, Human; Histone Acetyltransferases; Histones; Humans; Hydroxamic Acids; Immediate-Early Proteins; Mutation; Precipitin Tests; Promoter Regions, Genetic; Response Elements; RNA, Messenger; RNA, Viral; Saccharomyces cerevisiae Proteins; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Viral Proteins; Virus Replication; YY1 Transcription Factor

2000
Genes modulated by histone acetylation as new effectors of butyrate activity.
    FEBS letters, 2001, Jun-22, Volume: 499, Issue:3

    Topics: Acetylation; Butyrates; Colonic Neoplasms; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; GATA2 Transcription Factor; Gene Expression; Gene Expression Profiling; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; HT29 Cells; Humans; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured

2001
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF.
    Nucleic acids research, 2002, Jul-15, Volume: 30, Issue:14

    Topics: Acetamides; Azacitidine; Binding Sites; Blotting, Northern; Cells, Cultured; Cycloheximide; Decitabine; DNA-Binding Proteins; Down-Regulation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Hydroxamic Acids; Luciferases; Melanocytes; Membrane Glycoproteins; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Mutation; Oxidoreductases; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Transcription Factors; Tumor Cells, Cultured

2002
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells.
    Cancer letters, 2002, Dec-15, Volume: 188, Issue:1-2

    Topics: Antigens, Differentiation; Blotting, Northern; Blotting, Western; Butyrates; Cell Cycle Proteins; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Nuclear Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Tumor Cells, Cultured

2002
Deacetylase activity is required for cAMP activation of a subset of CREB target genes.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Acetyltransferases; Alcohol Oxidoreductases; Animals; Chromatin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Cycloheximide; DNA-Binding Proteins; Enhancer Elements, Genetic; Fungal Proteins; Genes, Reporter; Histone Acetyltransferases; Histone Deacetylases; Hydroxamic Acids; NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases; PC12 Cells; Phosphorylation; Precipitin Tests; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Repressor Proteins; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Up-Regulation

2003
The hTERT gene is embedded in a nuclease-resistant chromatin domain.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Binding Sites; Catalytic Domain; Cell Line; Cell Line, Tumor; Chromatin; Cycloheximide; Deoxyribonuclease I; DNA Primers; DNA-Binding Proteins; Fibroblasts; HeLa Cells; Histone Deacetylases; Humans; Hydroxamic Acids; Membrane Transport Proteins; Models, Biological; Plasma Membrane Neurotransmitter Transport Proteins; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Telomerase; Transcription, Genetic

2004
Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: a promising means to improved tumor detection and targeting.
    Cancer research, 2005, May-15, Volume: 65, Issue:10

    Topics: Animals; Base Sequence; Carrier Proteins; Cycloheximide; Dexamethasone; Female; Folate Receptors, GPI-Anchored; Gene Expression Regulation; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, SCID; Mifepristone; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cell Surface; Receptors, Glucocorticoid; Xenograft Model Antitumor Assays

2005
The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines.
    Molecular cancer, 2006, Feb-17, Volume: 5

    Topics: Active Transport, Cell Nucleus; Animals; Cell Cycle; Cell Nucleus; Cyclin D1; Cycloheximide; Cytoplasm; Enzyme Inhibitors; Exportin 1 Protein; Fatty Acids, Unsaturated; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Karyopherins; Leupeptins; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proto-Oncogene Mas; Receptors, Cytoplasmic and Nuclear; Transfection

2006
Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes.
    Reproduction (Cambridge, England), 2006, Volume: 131, Issue:3

    Topics: Acetylation; Animals; Chromatin; Cycloheximide; Enzyme Activation; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Immunoblotting; Immunohistochemistry; Maturation-Promoting Factor; Meiosis; Mesothelin; Mice; Mitogen-Activated Protein Kinase 1; Oocytes; Protein Synthesis Inhibitors; Purines; Roscovitine

2006
The extracellular release of HMGB1 during apoptotic cell death.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha

2006
Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:12

    Topics: Acetylation; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Histone Deacetylase Inhibitors; Histone Deacetylases; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Neoplasms; Proteasome Endopeptidase Complex; RNA, Messenger; Thymidylate Synthase

2006
De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists.
    Journal of virology, 2007, Volume: 81, Issue:17

    Topics: Azacitidine; Blotting, Northern; Cell Line; Cycloheximide; Decitabine; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Herpesvirus 4, Human; Herpesvirus 8, Human; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immediate-Early Proteins; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Trans-Activators; Viral Proteins; Virus Activation

2007
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium.
    American journal of respiratory and critical care medicine, 2010, May-01, Volume: 181, Issue:9

    Topics: Adolescent; Asthma; Azacitidine; Cells, Cultured; Child; Child, Preschool; Cycloheximide; Dexamethasone; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Matrix; Fibronectins; Homocystine; Humans; Hydroxamic Acids; Hypersensitivity; Microarray Analysis; Respiratory Mucosa; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

2010
Superinduction of leptin mRNA in mouse hypothalamic neurons.
    Neuroreport, 2012, Oct-24, Volume: 23, Issue:15

    Topics: Animals; Anisomycin; Cell Line; Cycloheximide; Gene Expression Regulation; Hydroxamic Acids; Hypothalamus; Leptin; Mice; Neurons; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger

2012
HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-05, Volume: 110, Issue:6

    Topics: Animals; Cycloheximide; Dexamethasone; Female; Genes, Viral; Herpesvirus 1, Human; Host-Pathogen Interactions; Humans; Hydroxamic Acids; Mice; Mice, Inbred CBA; MicroRNAs; Mutation; Recombinant Proteins; Repressor Proteins; RNA, Viral; Trigeminal Ganglion; Virus Activation; Virus Latency; Virus Replication

2013