cycloheximide has been researched along with thapsigargin in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (46.34) | 18.2507 |
| 2000's | 18 (43.90) | 29.6817 |
| 2010's | 4 (9.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Beck, HP; Brun, R; Cohen, SB; Dartois, V; Dharia, NV; Diagana, TT; Fidock, DA; Goh, A; González-Páez, GE; Jegla, T; Keller, TH; Lakshminarayana, SB; Lee, MC; McNamara, C; Nosten, F; Plouffe, DM; Renia, L; Rottmann, M; Russell, B; Schmitt, EK; Seitz, P; Spencer, KR; Suwanarusk, R; Tan, J; Winzeler, EA; Yeung, BK; Zou, B | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Alkhalaf, B; Ballejo, G; Gong, Y; Molnar, P; Murphy, LC; Murphy, LJ | 1 |
| Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ | 1 |
| Calderwood, SK; Mannheim-Rodman, LA; Price, BD | 1 |
| Hirasawa, N; Katoh, M; Kawamura, R; Matsui, N; Mue, S; Ohuchi, K; Watanabe, M; Yomogida, S | 1 |
| Chow, SC; Orrenius, S; Peters, I | 1 |
| Brostrom, CO; Brostrom, MA; Prostko, CR | 1 |
| Goebeler, M; Roth, J; Sorg, C; van den Bos, C; Wrocklage, V | 1 |
| Albrecht, BN; Hovis, JG; Lowe, WL; Meyer, T; Teasdale, RM; Yorek, MA | 1 |
| Escobales, N; Gonzalez, O; Martinez, J | 1 |
| An, S; Goetzl, EJ; Zeng, L | 1 |
| Aoki, T; Honjo, T; Kikuchi, H; Koike, T; Kondo, S; Nakano, T; Shibahara, K | 1 |
| Gulati, R; Peluso, JJ | 1 |
| Shea, TB | 1 |
| Culic, O; Gruwel, ML; Schrader, J | 1 |
| Hajimohammadreza, I; Nath, R; Raser, KJ; Wang, KK | 1 |
| Ohyashiki, T; Takadera, T | 1 |
| Buescher, ES; Chacon-Cruz, E; Davis, P; Oelberg, DG | 1 |
| Pozzan, T; Rudolph, HK; Strayle, J | 1 |
| Fitch, CA; Levenson, CW; Narayanan, VS; Song, Y; Yeiser, EC | 1 |
| Hsu, YW; Lin, WW | 1 |
| Furuyama, S; Modéer, T; Nakao, S; Ogata, Y; Segawa, M; Sugiya, H | 1 |
| Beyer, C; Engele, J; Ivanova, T; Küppers, E | 1 |
| Harvey, BJ; Urbach, V | 1 |
| Berger, SA; Soboloff, J | 1 |
| Chang, JP; Habibi, HR; Johnson, JD; Klausen, C | 1 |
| Consiglio, E; Di Jeso, B; Formisano, S; Leonardi, A; Mauro, C; Pacifico, F; Ulianich, L; Vito, P | 1 |
| Cavener, DR; Jiang, HY; Kaufman, RJ; McGrath, BC; Scheuner, D; Wek, RC; Wek, SA | 1 |
| Borner, C; Egger, L; Häcki, J; Rhême, C; Schneider, J; Tapernoux, M | 1 |
| Berger, SA; Zhang, Y | 1 |
| de Léséleuc, L; Denis, F | 1 |
| Baltzis, D; Koromilas, AE; Pluquet, O; Qu, LK | 1 |
| Abbruzzese, JL; Boise, LH; Carew, JS; Chiao, PJ; Dunner, K; Huang, P; McConkey, DJ; Nawrocki, ST | 1 |
| Doody, GM; Stephenson, S; Tooze, RM | 1 |
| Bensellam, M; Elouil, H; Guiot, Y; Jonas, JC; Pascal, SM; Schuit, FC; Vander Mierde, D | 1 |
| Falahatpisheh, H; Montoya-Durango, D; Nanez, A; Qian, Y; Ramos, KS; Tiffany-Castiglioni, E | 1 |
| Kurshan, N; Lann, D; LeRoith, D; Novosyadlyy, R; Vijayakumar, A; Yakar, S | 1 |
| Engedal, N; Seglen, PO | 1 |
| Chong, YH; Jhang, KA; Kim, HS; Park, JS | 1 |
41 other study(ies) available for cycloheximide and thapsigargin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Spiroindolones, a potent compound class for the treatment of malaria.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Cell Line; Drug Discovery; Drug Resistance; Erythrocytes; Female; Genes, Protozoan; Humans; Indoles; Malaria; Male; Mice; Models, Molecular; Mutant Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Protein Synthesis Inhibitors; Protozoan Proteins; Rats; Rats, Wistar; Spiro Compounds | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Phorbol esters differentially regulate the expression of insulin-like growth factor-binding proteins in endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Blotting, Northern; Calcimycin; Carrier Proteins; Cell Division; Cycloheximide; Endometrial Neoplasms; Enzyme Activation; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Kinetics; Protein Kinase C; RNA, Messenger; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1992 |
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms | 1992 |
Brefeldin A, thapsigargin, and AIF4- stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis.
Topics: 3T3 Cells; Aluminum; Aluminum Compounds; Animals; Brefeldin A; Carrier Proteins; Cell Hypoxia; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum Chaperone BiP; Ethers, Cyclic; Fluorides; Fluorine; Genistein; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Isoflavones; Membrane Proteins; Mice; Molecular Chaperones; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Terpenes; Thapsigargin | 1992 |
Inhibition of histamine release from RBL-2H3 cells by protein synthesis inhibitors.
Topics: Animals; Antigens; Calcium; Carcinogens; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Histamine Release; Ionomycin; Leukemia, Basophilic, Acute; Protein Biosynthesis; Proteins; Puromycin; Rats; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1994 |
Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis.
Topics: Animals; Apoptosis; Calcium-Transporting ATPases; Cell Survival; Cells, Cultured; Cycloheximide; DNA; Emetine; Ionomycin; Male; Methylprednisolone; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Terpenes; Thapsigargin; Thymus Gland | 1995 |
Reversible phosphorylation of eukaryotic initiation factor 2 alpha in response to endoplasmic reticular signaling.
Topics: Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Line; Cycloheximide; Dithiothreitol; Egtazic Acid; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Pactamycin; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Puromycin; Signal Transduction; Terpenes; Thapsigargin; Tunicamycin | 1993 |
Expression of the calcium-binding proteins MRP8 and MRP14 in monocytes is regulated by a calcium-induced suppressor mechanism.
Topics: Antigens, Differentiation; Blotting, Northern; Blotting, Western; Calcimycin; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression Regulation; Humans; Monocytes; RNA, Messenger; Suppression, Genetic; Terpenes; Thapsigargin | 1994 |
Intracellular calcium regulates insulin-like growth factor-I messenger ribonucleic acid levels.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Fibroblast Growth Factor 2; Fibroblasts; Insulin-Like Growth Factor I; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Signal Transduction; Spectrometry, Fluorescence; Terpenes; Thapsigargin | 1993 |
Upregulation of Na(+)-dependent alanine transport in vascular endothelial cells by serum: role of intracellular Ca2+.
Topics: Alanine; Amino Acid Transport Systems; Animals; Biological Transport, Active; Blood; Calcium; Carrier Proteins; Cattle; Cells, Cultured; Cycloheximide; Egtazic Acid; Endothelium, Vascular; Ouabain; Pertussis Toxin; Potassium; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Up-Regulation; Virulence Factors, Bordetella | 1994 |
Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor.
Topics: Adenine; Alprostadil; Blotting, Northern; Bucladesine; Calcium; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, T-Cell; Matrix Metalloproteinase 9; Misoprostol; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; RNA, Messenger; T-Lymphocytes; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Induction of Bip mRNA upon programmed cell death of differentiated PC12 cells as well as rat sympathetic neurons.
Topics: Actins; Animals; Apoptosis; Calcium; Carrier Proteins; Cell Differentiation; Cyclic AMP; Cycloheximide; Dactinomycin; Endoplasmic Reticulum Chaperone BiP; Ganglia, Sympathetic; Heat-Shock Proteins; Molecular Chaperones; Nerve Growth Factors; Neurons; PC12 Cells; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Thapsigargin | 1997 |
Opposing actions of hepatocyte growth factor and basic fibroblast growth factor on cell contact, intracellular free calcium levels, and rat ovarian surface epithelial cell viability.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3T3 Cells; Animals; Apoptosis; Calcium; Cell Adhesion; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Egtazic Acid; Epithelial Cells; Female; Fibroblast Growth Factor 2; Hepatocyte Growth Factor; Kinetics; Mice; Ovary; Rats; Thapsigargin | 1997 |
Restriction of microM-calcium-requiring calpain activation to the plasma membrane in human neuroblastoma cells: evidence for regionalized influence of a calpain activator protein.
Topics: Calcimycin; Calcium; Calpain; Cell Membrane; Cycloheximide; Cytosol; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Half-Life; Humans; Ionomycin; Ionophores; Isoenzymes; Membrane Proteins; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Neurons; Protein Synthesis Inhibitors; Thapsigargin; Tumor Cells, Cultured | 1997 |
Energy turnover of vascular endothelial cells.
Topics: Actins; Adenosine Triphosphatases; Adenosine Triphosphate; Androstadienes; Animals; Antimycin A; Aorta; Cells, Cultured; Cycloheximide; Cytochalasin D; Deoxyglucose; Diacetyl; Endothelium, Vascular; Energy Metabolism; Enzyme Inhibitors; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Phosphorus; Swine; Thapsigargin; Wortmannin | 1997 |
Thapsigargin induces apoptosis in SH-SY5Y neuroblastoma cells and cerebrocortical cultures.
Topics: Animals; Apoptosis; Calcium; Calcium-Transporting ATPases; Cerebral Cortex; Cycloheximide; Dantrolene; DNA Fragmentation; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Neuroblastoma; Neurons; Rats; Thapsigargin; Tumor Cells, Cultured | 1997 |
Apoptotic cell death and CPP32-like activation induced by thapsigargin and their prevention by nerve growth factor in PC12 cells.
Topics: Animals; Apoptosis; Calcium; Calcium-Transporting ATPases; Caspase 1; Caspase 3; Caspases; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Nerve Growth Factors; Neurons; Oligopeptides; PC12 Cells; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Thapsigargin | 1998 |
Membrane depolarization and depletion of intracellular calcium stores are associated with delay of apoptosis in human neutrophils.
Topics: Annexin A5; Apoptosis; Calcium; Cell Membrane; Cycloheximide; Extracellular Space; Fluorescein-5-isothiocyanate; Humans; Intracellular Fluid; Membrane Potentials; Neutrophils; Thapsigargin; Time Factors | 1998 |
Steady-state free Ca(2+) in the yeast endoplasmic reticulum reaches only 10 microM and is mainly controlled by the secretory pathway pump pmr1.
Topics: Aequorin; ATP-Binding Cassette Transporters; Calcimycin; Calcium; Calcium-Transporting ATPases; Cycloheximide; Endoplasmic Reticulum; Enzyme Inhibitors; Golgi Apparatus; Homeostasis; Ionophores; Models, Biological; Molecular Chaperones; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sarcoplasmic Reticulum; Temperature; Thapsigargin; Vanadates | 1999 |
Regulation of mitochondrial cytochrome b mRNA by copper in cultured human hepatoma cells and rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Chelating Agents; Copper; Cycloheximide; Cytochrome b Group; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrogen Peroxide; Liver; Male; Mitochondria, Liver; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Analysis, DNA; Thapsigargin; Tumor Cells, Cultured; Zinc | 1999 |
Cycloheximide-induced cPLA(2) activation is via the MKP-1 down-regulation and ERK activation.
Topics: Animals; Anisomycin; Arachidonic Acid; Blotting, Western; Calcium; Cell Cycle Proteins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Dual Specificity Phosphatase 1; Enzyme Activation; Enzyme Inhibitors; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphoprotein Phosphatases; Protein Biosynthesis; Protein Phosphatase 1; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Thapsigargin; Time Factors; Vanadates | 2000 |
Bradykinin induces a rapid cyclooxygenase-2 mRNA expression via Ca2+ mobilization in human gingival fibroblasts primed with interleukin-1 beta.
Topics: Bradykinin; Calcium; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Dactinomycin; Dexamethasone; Fibroblasts; Gingiva; Humans; Interleukin-1; Ionomycin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Thapsigargin | 2001 |
Estrogen stimulates brain-derived neurotrophic factor expression in embryonic mouse midbrain neurons through a membrane-mediated and calcium-dependent mechanism.
Topics: Animals; Aromatase Inhibitors; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Culture Media, Serum-Free; Cycloheximide; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estradiol; Fadrozole; Female; Fulvestrant; Gene Expression Regulation; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred BALB C; Nerve Growth Factors; Neurons; Receptor, trkB; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Thapsigargin | 2001 |
Rapid and non-genomic reduction of intracellular [Ca(2+)] induced by aldosterone in human bronchial epithelium.
Topics: Adenylyl Cyclases; Aldosterone; Bronchi; Calcium; Cell Line, Transformed; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Inhibitors; Epithelial Cells; Glucocorticoids; GTP-Binding Proteins; Humans; Intracellular Membranes; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Protein Synthesis Inhibitors; Sodium; Spironolactone; Thapsigargin; Time Factors; Uridine Triphosphate; Vanadates | 2001 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Death; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Econazole; Endoplasmic Reticulum; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Mast Cells; Mice; Mice, Inbred C57BL; Mitochondria; Phosphorylation; Protein Synthesis Inhibitors; Ryanodine; Spectrometry, Fluorescence; Thapsigargin; Time Factors | 2002 |
Function-specific calcium stores selectively regulate growth hormone secretion, storage, and mRNA level.
Topics: Animals; Calcium; Cycloheximide; Exocytosis; Goldfish; Growth Hormone; Pituitary Gland; Potassium Chloride; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Thapsigargin | 2002 |
Endoplasmic reticulum stress causes thyroglobulin retention in this organelle and triggers activation of nuclear factor-kappa B via tumor necrosis factor receptor-associated factor 2.
Topics: Animals; Calcium; Cells, Cultured; Cycloheximide; Electrophoresis; Endoplasmic Reticulum; Fibroblasts; Genes, Reporter; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Precipitin Tests; Protein Synthesis Inhibitors; Proteins; Signal Transduction; Stress, Mechanical; Thapsigargin; Thyroglobulin; TNF Receptor-Associated Factor 2; Tunicamycin | 2002 |
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.
Topics: Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Activation; Eukaryotic Initiation Factor-2; Heterozygote; Immunoblotting; Luciferases; Mice; Microscopy, Confocal; Microscopy, Fluorescence; NF-kappa B; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Protein Transport; Thapsigargin; Transcription, Genetic; Transcriptional Activation | 2003 |
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Monoclonal; Apoptosis; Blotting, Western; Brefeldin A; Caspase 3; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Line, Tumor; Cycloheximide; fas Receptor; Fibroblasts; Flow Cytometry; Gene Expression Regulation; HeLa Cells; Humans; Interleukin-3; Mice; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Models, Biological; Phagocytosis; Proto-Oncogene Proteins c-bcl-2; Rats; Serine Endopeptidases; Sulfones; Thapsigargin; Tunicamycin; U937 Cells | 2003 |
Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Area Under Curve; Calcium; Cell Death; Cell Line, Tumor; Cycloheximide; Dithiothreitol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Econazole; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Etoposide; Fas Ligand Protein; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Phenotype; Ribosomes; Thapsigargin; Time Factors; Tunicamycin | 2004 |
Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cell Line; Cycloheximide; DNA Damage; DNA-Binding Proteins; Endoplasmic Reticulum; Etoposide; Fas Ligand Protein; Fibroblasts; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Membrane Glycoproteins; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thapsigargin; Transcription Factors; Transfection; Tumor Necrosis Factors | 2006 |
Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta.
Topics: Animals; Cell Line; Cycloheximide; Doxorubicin; Endoplasmic Reticulum; Fatty Acids, Unsaturated; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leupeptins; Mice; Phosphorylation; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Protein Transport; Serine; Signal Transduction; Thapsigargin; Tumor Suppressor Protein p53; Tunicamycin; Ubiquitin; Ubiquitin-Protein Ligases | 2005 |
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Calcium; Caspase Inhibitors; Caspases; Caspases, Initiator; Cycloheximide; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Molecular Chaperones; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational; Pyrazines; RNA, Small Interfering; Thapsigargin; Transcription Factor CHOP; Ubiquitin | 2005 |
BLIMP-1 is a target of cellular stress and downstream of the unfolded protein response.
Topics: Animals; B-Lymphocytes; Cycloheximide; Dithiothreitol; DNA-Binding Proteins; eIF-2 Kinase; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; HeLa Cells; HL-60 Cells; Humans; Macrophages; Mice; Mice, Inbred C57BL; Nuclear Proteins; Positive Regulatory Domain I-Binding Factor 1; Protein Folding; Protein Synthesis Inhibitors; Regulatory Factor X Transcription Factors; Repressor Proteins; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction; Thapsigargin; Transcription Factors | 2006 |
Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets.
Topics: Alternative Splicing; Animals; Calcium; Culture Media; Cycloheximide; Endoplasmic Reticulum; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Kinetics; Molecular Chaperones; Phosphorylation; Protein Synthesis Inhibitors; Rats; Thapsigargin | 2007 |
Activation profiles of HSPA5 during the glomerular mesangial cell stress response to chemical injury.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Mercuric Chloride; Mesangial Cells; Mice; Molecular Chaperones; Nucleic Acid Synthesis Inhibitors; Organometallic Compounds; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Stress, Physiological; Thapsigargin; Transcription, Genetic; Transfection | 2007 |
Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cycloheximide; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Humans; Insulin-Like Growth Factor I; Mice; NIH 3T3 Cells; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Recombinant Proteins; Signal Transduction; Thapsigargin | 2008 |
Autophagy of cytoplasmic bulk cargo does not require LC3.
Topics: Adenine; Animals; Autophagy; Cell Line, Tumor; Cycloheximide; Cytoplasm; Hepatocytes; Humans; Microtubule-Associated Proteins; Rats; Thapsigargin | 2016 |
Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages.
Topics: Amyloid beta-Peptides; Anti-Inflammatory Agents; Antibodies; c-Mer Tyrosine Kinase; Calcium; Calcium Ionophores; Cell Fractionation; Cycloheximide; Gene Expression Regulation; Humans; Interleukin-1beta; Ionomycin; Isothiocyanates; Nitriles; Peptide Fragments; Protein Synthesis Inhibitors; RNA, Small Interfering; Signal Transduction; Sulfones; Sulfoxides; Thapsigargin; THP-1 Cells; Tumor Necrosis Factor-alpha | 2018 |