cycloheximide has been researched along with pregnenolone in 80 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (87.50) | 18.7374 |
| 1990's | 5 (6.25) | 18.2507 |
| 2000's | 4 (5.00) | 29.6817 |
| 2010's | 1 (1.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farese, RV; Prudente, WJ | 2 |
| Bakker, CP; van der Molen, HJ; van der Plank-van Winsen, MP | 1 |
| Aaronson, SA; Dunn, CY; Stephenson, JR | 1 |
| Jefcoate, CR | 1 |
| Jefcoate, CR; Orme-Johnson, WH | 1 |
| Hasegawa, K; Igarashi, T; Itoh, Y; Kawakami, F; Moriwaki, K; Nishikawa, M; Sugase, T | 1 |
| Carchman, RA; Harris, LS; Warner, W | 1 |
| Laychock, SG; Rubin, RP | 1 |
| McCarthy, JL; Peterson, JA; Simpson, ER | 1 |
| Catt, KJ; Cigorraga, SB; Dufau, ML | 1 |
| Hall, PF; Nakamura, M; Watanuki, M | 1 |
| Mason, JI; Robidoux, WF | 1 |
| Crivello, JF; Jefcoate, CR | 1 |
| Arthur, JR; Boyd, GS; Mason, JI | 2 |
| Boyd, GS; Hume, R | 1 |
| Kalkman, ML; Van Der Molen, HJ; Van Der Vusse, GJ; Van Winsen, MP | 1 |
| Cavallaro, S; Costa, E; Guidotti, A; Korneyev, A | 1 |
| Begum-Hasan, J; Murphy, BE | 1 |
| Jefcoate, CR; McNamara, BC | 2 |
| Dhariwal, MS; Jefcoate, CR; McNamara, BC; Privalle, CT | 1 |
| Gangnerau, MN; Picon, R; Rouiller, V | 1 |
| Bhattacharya, S; Deb, S | 1 |
| Rommerts, FF; Terpstra, P; van der Molen, HJ | 1 |
| Kolanowski, J; Lambert, F; Lammerant, J | 1 |
| Igarashi, Y; Kimura, T | 1 |
| Freeman, DA | 1 |
| Takagi, K | 1 |
| Harding, BW; Natarajan, RD | 1 |
| Georgiou, M; Payne, AH; Quinn, PG | 1 |
| Osawa, N | 1 |
| Boyd, GS; Brown, MJ | 1 |
| Davis, WW; Dexter, RN; Garren, LD; Ney, RL | 1 |
| Davis, WW; Garren, LD | 1 |
| Dzsinich, C; Okrös, I; Szabó, D | 1 |
| Kowal, J | 1 |
| Dexter, RN; Fishman, LM; Ney, RL | 1 |
| Cox, RP | 1 |
| Beinert, H; Boyd, GS; Brownie, AC; Jefcoate, CR; Orme-Johnson, WH; Simpson, ER | 1 |
| Garren, LD; Gill, GN; Masui, H; Walton, GM | 1 |
| Boyd, GS; Brownie, AC; Jefcoate, CR; Simpson, ER | 2 |
| Drummond, HB; Fevold, HR | 1 |
| Sharma, RK | 2 |
| Mahaffee, D; Ney, RL; Reitz, RC | 1 |
| Boyd, GS; Jefcoate, CR; McCarthy, JL; Simpson, ER | 1 |
| Bell, JJ; Cheng, SC; Harding, BW | 1 |
| Alfano, J; Beinert, H; Brownie, AC; Jefcoate, CR; Orme-Johnson, W; Simpson, ER | 1 |
| Boyd, GS; Trzeciak, WH | 1 |
| Shin, SI | 1 |
| Garren, LD | 1 |
| Koritz, SB; Kumar, AM | 1 |
| Dardachti, D; Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B | 1 |
| Arthur, JR; Boyd, GS | 1 |
| Schuetz, AW | 1 |
| Schorderet-Slatkine, S | 1 |
| Boyd, GS; Jefcoate, CR; Simpson, ER | 1 |
| LeVier, RR; Spaziani, E | 1 |
| Neher, R; Podesta, EJ; Solano, AR | 1 |
| Demers, LM; Kolp, LA; Strauss, JF; Toaff, ME; Veldhuis, JD | 1 |
| Bakker, GH; Rommerts, FF; van der Molen, HJ | 1 |
| Chuang, LT; Farese, RV; Prudente, WJ | 1 |
| Farese, RV; Sabir, AM | 1 |
| Brinkman, AO; Rommerts, FF | 1 |
| Chanderbhan, R; Dennis, P; Irwin, D; Lambeth, JD; Noland, BJ; Scallen, TJ; Vahouny, GV | 1 |
| Elliott, ME; Goodfriend, TL | 1 |
| Chanderbhan, R; Dennis, P; Fiskum, G; Noland, BJ; Scallen, TJ; Vahouny, GV | 1 |
| Boyd, GS; Leaver, HA | 1 |
| Harding, BW; Tsao, K; von Dippe, PJ | 1 |
| Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ | 1 |
| Ambrosio, C; Barbaccia, ML; Massotti, M; Roscetti, G; Trabucchi, M | 1 |
| Bhattacharya, S; Datta, M; Nagendra Prasad, RJ | 1 |
| Cascio, C; De Leo, G; Guarneri, M; Guarneri, P; Guarneri, R; Piccoli, F; Russo, D | 1 |
| Bhattacharyya, S; Bhattacharyya, SP; Mukherjee, D; Sen, U | 1 |
| Aoshika, K; Chiyo, T; Kominami, S; Ohta, Y; Yamazaki, T | 1 |
| Cymeryng, CB; Gadda, L; Grion, N; Pannunzio, V; Podesta, EJ; Pomeraniec, Y | 1 |
| Boyd, KN; Kumar, S; Morrow, AL; O'Buckley, TK; Porcu, P | 1 |
5 review(s) available for cycloheximide and pregnenolone
| Article | Year |
|---|---|
[Adrenocorticotrophic hormone (ACTH)].
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Chloramphenicol; Cholesterol; Chromatography, DEAE-Cellulose; Cyclic AMP; Cycloheximide; Dactinomycin; Mitochondria; Pregnenolone; Puromycin; Rats | 1971 |
On the mechanism of action of ACTH.
Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Cattle; Cell Fractionation; Cholesterol; Corticosterone; Cyclic AMP; Cycloheximide; DNA; DNA Nucleotidyltransferases; DNA Replication; Hypophysectomy; Models, Biological; Nucleotides; Phosphotransferases; Pituitary Gland; Pregnenolone; Protamines; Protein Binding; Proteins; Rats; RNA, Messenger; Thymidine Kinase | 1971 |
Cholesterol hydroxylation in the adrenal cortex and liver.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cattle; Chemistry, Organic; Cholesterol; Chromatography, DEAE-Cellulose; Cycloheximide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Iron Isotopes; Isocitrates; Liver; Malates; Microsomes, Liver; Organic Chemistry Phenomena; Oxygen Consumption; Pregnenolone; Rats; Rotenone | 1972 |
The mechanism of action of adrenocorticotropic hormone.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Atrophy; Chemical Phenomena; Chemistry; Cholesterol; Corticosterone; Cyclic AMP; Cycloheximide; Hypophysectomy; Mitochondria; Models, Biological; NADP; Pregnenolone; Progesterone; Protein Biosynthesis; RNA; Steroids; Tritium | 1968 |
Modulation of steroidogenic activities in testis Leydig cells.
Topics: Aging; Animals; Aromatase; Cell Membrane; Cell Separation; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Cycloheximide; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; Oxidoreductases; Phosphorylation; Pregnenolone; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, LH; Sertoli Cells; Testosterone | 1981 |
75 other study(ies) available for cycloheximide and pregnenolone
| Article | Year |
|---|---|
Corticotropin-induced changes in a soluble desmolase preparation.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Caproates; Carbon Monoxide; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Cytosol; Male; Mitochondria; NADP; Oxidoreductases; Pregnenolone; Rats | 1978 |
On the role of calcium in adrenocorticotropin-induced changes in mitochondrial pregnenolone synthesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcium; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Male; Mitochondria; NADP; Pregnenolone; Rats | 1978 |
Effects of cholesterol, hydroxycholesterols and calcium on pregnenolone production rates in mitochondrial fractions from rat testes.
Topics: Animals; Calcium; Cholesterol; Cycloheximide; Hydroxycholesterols; Kinetics; Luteinizing Hormone; Male; Mitochondria; NADP; Pregnenolone; Rats; Structure-Activity Relationship; Testis | 1979 |
Interactions of chemical inducers and steroid enhancers of endogenous mouse type-C RNA viruses.
Topics: Aldosterone; Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Crosses, Genetic; Cycloheximide; Dexamethasone; Gammaretrovirus; Hydrocortisone; Idoxuridine; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Pregnenolone; Rauscher Virus; Retroviridae; RNA-Directed DNA Polymerase; Virus Replication | 1975 |
Cytochrome P-450 of adrenal mitochondria. Spin states as detected by difference spectroscopy.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Binding Sites; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Hydroxysteroids; Kinetics; Mitochondria; Pregnenolone; Protein Binding; Protein Conformation; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Stress, Physiological | 1975 |
Cytochrome P-450 of adrenal mitochondria. In vitro and in vivo changes in spin states.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Calcium; Cycloheximide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Hydroxycholesterols; Hypoxia; Malates; Mitochondria; Phosphates; Phosphatidylcholines; Pregnenolone; Protein Binding; Protein Conformation; Rats; Species Specificity; Stress, Physiological | 1975 |
[Studies on the responsiveness of human adrenocortical tumors to ACTH the clinical and experimental observations (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Animals; Carcinoma; Cyclic AMP; Cycloheximide; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mitochondria; Pregnenolone; Progesterone; Rats | 1975 |
Inhibition of cortiocosteroidogenesis by delta-9-tetrahydrocannabinol.
Topics: 20-alpha-Dihydroprogesterone; Adrenocorticotropic Hormone; Cell Division; Cell Line; Cholera Toxin; Cyclic AMP; Cycloheximide; Dronabinol; Oxygen Consumption; Pregnenolone; Progesterone | 1977 |
Regulation of steroidogenesis and prostaglandin formation in isolated adrenocortical cells: the effects of pregnenolone and cycloheximide.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cats; Cycloheximide; In Vitro Techniques; Pregnenolone; Prostaglandins E; Prostaglandins F | 1977 |
Evidence that the cycloheximide-sensitive site of adrenocorticotropic hormone action is in the mitochondrion. Changes in pregnenolone formation, cholesterol content, and the electron paramagnetic resonance spectra of cytochrome P-450.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Kinetics; Mitochondria; Pregnenolone; Rats | 1978 |
Regulation of luteinizing hormone receptors and steroidogenesis in gonadotropin-desensitized leydig cells.
Topics: Animals; Chorionic Gonadotropin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Rats; Receptors, Cell Surface; Steroids; Testosterone | 1978 |
On the role of protein synthesis in the response of adrenal tumor cells to ACTH.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Bucladesine; Cell Line; Chloramphenicol; Cholesterol; Cycloheximide; Dactinomycin; Mitochondria; Pregnenolone; Protein Biosynthesis; Puromycin | 1978 |
Pregnenolone biosynthesis in isolated cells of Snell rat adrenocortical carcinoma 494.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Carcinoma; Cholesterol; Cycloheximide; Cytochalasin B; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Male; Neoplasms, Experimental; Pregnenolone; Rats | 1978 |
The effects of cytochalasin B and vinblastine on movement of cholesterol in rat adrenal glands.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Cholesterol; Colchicine; Cycloheximide; Cytochalasin B; Female; Hypophysectomy; Kinetics; Pregnenolone; Rats; Vinblastine | 1979 |
Control of sterol metabolism in rat adrenal mitochondria.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Female; Mitochondria; Pregnenolone; Rats; Sterols; Stress, Physiological; Structure-Activity Relationship | 1978 |
Cholesterol metabolism and steroid-hormone production.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Mitochondria; Oxidation-Reduction; Pregnenolone; Rats | 1978 |
The effect of calclium ions on the metabolism of exogenous cholesterol by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Calcium; Cholesterol; Cycloheximide; Female; Kinetics; Mitochondria; Pregnenolone; Rats; Stress, Physiological | 1976 |
On the regulation of rat testicular steroidogenesis. Short term effect of luteinizing hormone and cycloheximide in vivo and Ca2+ in vitro on steroid production in cell-free systems.
Topics: Animals; Calcium; Cell-Free System; Cycloheximide; Hydroxysteroid Dehydrogenases; Luteinizing Hormone; Male; Mitochondria; Pregnenolone; Rats; Steroids; Testis; Testosterone; Time Factors | 1975 |
Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Benzodiazepinones; Convulsants; Corticosterone; Cyclic AMP; Cycloheximide; Diazepam Binding Inhibitor; Hypophysectomy; Isoquinolines; Male; Mitochondria; Molecular Sequence Data; Neuropeptides; Pregnenolone; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; RNA | 1992 |
Influence of 19-nortestosterone and androgens on progesterone biosynthetic enzymes in early human placental explants.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Female; Humans; Hydroxycholesterols; Isomerism; Nandrolone; Placenta; Pregnenolone; Progesterone | 1992 |
Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from adrenocorticotropic hormone-treated rats: reconstitution of the isocitrate response with succinate and low concentrations of isocitrate.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Isocitrates; Kinetics; Mitochondria; Oligomycins; Oxidative Phosphorylation; Pregnenolone; Rats; Succinates | 1990 |
ACTH control of cholesterol side-chain cleavage at adrenal mitochondrial cytochrome P-450scc. Regulation of intramitochondrial cholesterol transfer.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Cyclophosphamide; Cytochrome P-450 Enzyme System; Female; Intracellular Membranes; Kinetics; Mitochondria; Pregnenolone; Rats | 1987 |
Synergistic stimulation of pregnenolone synthesis in rat adrenal mitochondria by n-hexane and cardiolipin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cardiolipins; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Drug Synergism; Female; Hexanes; Isocitrates; Kinetics; Mitochondria; NADP; Pregnenolone; Rats | 1988 |
Production of C21 steroids in rat fetal ovaries.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cycloheximide; Female; Hydroxycholesterols; Kinetics; Organ Culture Techniques; Ovary; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Spironolactone; Steroid 17-alpha-Hydroxylase | 1988 |
Mechanism involved in gonadotropin stimulation of ovarian steroidogenesis.
Topics: Animals; Cholesterol; Chromatography; Chromatography, Gel; Cyclic AMP; Cycloheximide; Female; Fishes; Gonadotropins; Hydrolysis; In Vitro Techniques; Luteinizing Hormone; Mitochondria; Oocytes; Ovary; Peptide Hydrolases; Pregnenolone | 1988 |
Are polyphosphorylated phospholipids involved in the hormonal control of cholesterol side-chain cleavage activity in tumour Leydig cells?
Topics: Animals; Bucladesine; Cardiolipins; Cycloheximide; Cytochrome P-450 Enzyme System; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mitochondria; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Pregnenolone; Quinacrine | 1985 |
The mechanism of the prolonged stimulatory effect of corticotrophin on pregnenolone production by guinea-pig adrenocortical mitochondria.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Calcium; Cholesterol; Cycloheximide; Guinea Pigs; Mitochondria; Pregnenolone; Stimulation, Chemical | 1986 |
Adrenic acid content in rat adrenal mitochondrial phosphatidylethanolamine and its relation to ACTH-mediated stimulation of cholesterol side chain cleavage reaction.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Arachidonic Acids; Cardiolipins; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; Cycloheximide; Dose-Response Relationship, Drug; Erucic Acids; Fatty Acids; Fatty Acids, Unsaturated; Male; Mitochondria; Oxidoreductases; Phosphatidylethanolamines; Pregnenolone; Rats; Rats, Inbred Strains; Triglycerides | 1986 |
Constitutive steroidogenesis in the R2C Leydig tumor cell line is maintained by the adenosine 3',5'-cyclic monophosphate-independent production of a cycloheximide-sensitive factor that enhances mitochondrial pregnenolone biosynthesis.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Cytoplasm; Lactates; Leydig Cell Tumor; Leydig Cells; Male; Mitochondria; Pregnenolone; Progesterone; Protein Kinases; Rats | 1987 |
[Effects of prostaglandin F2 alpha on steroidogenesis of the PMSG-hCG primed rat ovary in luteolysis].
Topics: 20-alpha-Dihydroprogesterone; Animals; Biological Transport; Cholesterol; Chorionic Gonadotropin; Corpus Luteum; Cycloheximide; Dinoprost; Female; Gonadotropins, Equine; Hydroxysteroid Dehydrogenases; Luteolysis; Luteolytic Agents; Mitochondria; Ovary; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains | 1988 |
Cholesterol side chain cleavage in rat adrenal supported by outer mitochondrial membrane NADH-semidehydroascorbate reductase.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Butylated Hydroxyanisole; Catalase; Cholesterol; Cold Temperature; Cosyntropin; Cycloheximide; Female; Malates; Mitochondria; NADH, NADPH Oxidoreductases; Pregnenolone; Rats; Rats, Inbred Strains | 1985 |
Differences in the control of sterol metabolism between mouse and rat Leydig cells.
Topics: Animals; Biological Transport; Cholesterol; Cycloheximide; Hydroxycholesterols; In Vitro Techniques; Leydig Cells; Male; Pregnenolone; Rats; Rats, Inbred Strains; Species Specificity; Sterols | 1985 |
The specificity of the rat-liver cholesterol 7alpha-hydroxylase.
Topics: Alcohol Oxidoreductases; Aminopyrine N-Demethylase; Androstenols; Animals; Cholesterol; Cholestyramine Resin; Cycloheximide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Phenobarbital; Pregnenolone; Protein Binding; Rats; Time Factors | 1974 |
A study of mechanisms by which adrenocorticotropic hormone maintains adrenal steroidogenic responsiveness.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Corticosterone; Cycloheximide; Hypophysectomy; In Vitro Techniques; Male; Pregnenolone; Progesterone; Protein Biosynthesis; Rats | 1967 |
On the mechanism of action of adrenocorticotropic hormone. The inhibitory site of cycloheximide in the pathway of steroid biosynthesis.
Topics: Acetates; Adrenocorticotropic Hormone; Animals; Cholesterol; Corticosterone; Cycloheximide; Depression, Chemical; Female; Hypophysectomy; Pituitary Gland; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Tritium | 1968 |
Cycloheximide-induced ultrastructural changes in the adrenal cortex of the rat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Cycloheximide; Female; Male; Microscopy, Electron; Mixed Function Oxygenases; Pregnenolone; Rats | 1969 |
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1970 |
Stimulation of adrenal cholesterol uptake from plasma by adrenocorticotrophin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Carbon Isotopes; Cholesterol; Cycloheximide; Depression, Chemical; Hydrocortisone; Hypophysectomy; Male; Pregnenolone; Protein Biosynthesis; Rats; Stimulation, Chemical; Tritium | 1970 |
Early events in hormonal induction of alkaline phosphatase in human cell culture: hormone-cell interaction and its dependence of DNA replication.
Topics: Aldosterone; Alkaline Phosphatase; Antigen-Antibody Reactions; Butyrates; Carbon Isotopes; Cell Line; Chromatography, Gel; Corticosterone; Cortisone; Cyclic AMP; Cycloheximide; Enzyme Induction; Epinephrine; Female; HeLa Cells; Humans; Hydrocortisone; Hydroxyprogesterones; Kinetics; Leucine; Mitosis; Precipitin Tests; Prednisolone; Pregnenolone; Progesterone; Protein Biosynthesis; Spectrophotometry; Theophylline; Tritium | 1971 |
Effect of ACTH on cholesterol side-chain cleavage in rat adrenal mitochondria.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Cycloheximide; Cytochromes; Electron Spin Resonance Spectroscopy; Ethyl Ethers; Female; Isocitrates; Mitochondria; Pregnenolone; Rats; Spectrophotometry; Stress, Physiological | 1972 |
The effect of ether anaesthesia stress on cholesterol-side-chain cleavage and cytochrome P450 in rat-adrenal mitochondria.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anesthesia, Inhalation; Animals; Biological Transport; Carbon Isotopes; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Ethyl Ethers; Female; Isocitrates; Mitochondria; Pregnenolone; Rats; Spectrophotometry; Steroid Hydroxylases | 1972 |
Factors affecting the adrenocorticotropic hormone stimulation of rabbit adrenal 17alpha-hydroxylase activity.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Carbon Radioisotopes; Corticosterone; Cortisone; Cycloheximide; Cytosol; Dialysis; Hydrocortisone; Hydroxylation; Male; Microsomes; Mitochondria; Mixed Function Oxygenases; Pregnenolone; Progesterone; Rabbits; Subcellular Fractions | 1973 |
Regulation of steroidogenesis by adrenocorticotropic hormone in isolated adrenal cells of rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Bucladesine; Cholesterol; Chromatography, Thin Layer; Corticosterone; Cyclic AMP; Cycloheximide; Hydroxysteroids; In Vitro Techniques; Male; Pregnenolone; Rats; Spectrometry, Fluorescence; Tritium | 1973 |
The mechanism of action of adrenocroticotropic hormone. The role of mitochondrial cholesterol accumulation in the regulation of steroidogenesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Bucladesine; Cholesterol; Chromatography, Gas; Cyclic AMP; Cycloheximide; Cytosol; Hypophysectomy; Male; Microscopy, Electron; Mitochondria; Pituitary Gland; Pregnenolone; Rats; Subcellular Fractions; Swine; Time Factors | 1974 |
Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Effect of actinomycin D on cGMP-induced steroidogenesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Radioisotopes; Cholesterol; Corticosterone; Cyclic GMP; Cycloheximide; Dactinomycin; In Vitro Techniques; Isotope Labeling; Leucine; Pregnenolone; Protein Biosynthesis; Rats; Spectrometry, Fluorescence; Time Factors; Tritium | 1974 |
Effect of calcium ions on steroid-binding spectra and pregnenolone formation in rat-adrenal mitochondria.
Topics: Adrenal Glands; Androstenediols; Animals; Binding Sites; Calcium; Carbon Radioisotopes; Cattle; Cycloheximide; Cytochrome P-450 Enzyme System; Edetic Acid; Electron Spin Resonance Spectroscopy; Female; Hydroxycholesterols; Kinetics; Magnesium; Mitochondria; Oxygen Consumption; Pregnenolone; Protein Binding; Rats; Receptors, Cell Surface; Serum Albumin, Bovine; Spectrophotometry | 1974 |
Control of substrate flux and adrenal cytochrome P-450.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cattle; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Electron Transport; Microsomes; Mitochondria; Polyethylene Glycols; Pregnenolone; Rats | 1973 |
Effect of ACTH on adrenal mitochondrial cytochrome P-450 in the rat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chemical Phenomena; Chemistry; Cycloheximide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Male; Mitochondria; Pregnenolone; Rats; Species Specificity; Stress, Physiological | 1973 |
Cholesterol metabolism in the adrenal cortex: studies on the mode of action of ACTH.
Topics: Adenosine Triphosphate; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Cyclic AMP; Cycloheximide; Lipoproteins; Mitochondria; Phospholipids; Pregnenolone; Protein Kinases; Rats; Stress, Physiological; Theophylline | 1973 |
Studies on interstitial cells in tissue culture: steroid biosynthesis in monolayers of mouse testicular interstitial cells.
Topics: Adenine Nucleotides; Animals; Chorionic Gonadotropin; Culture Techniques; Cycloheximide; Follicle Stimulating Hormone; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mice; Microscopy, Phase-Contrast; NAD; NADP; Neoplasm Transplantation; Pregnenolone; Progesterone; Prolactin; Testis | 1967 |
On the mechanism of action of the adrenocorticotrophic hormone. The stimulation of the activity of enzymes involved in pregnenolone synthesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcium; Corticosterone; Cycloheximide; Electron Transport; Feedback; Kinetics; Magnesium; Male; Microsomes; Mitochondria; Mitochondrial Swelling; NAD; NADP; Pregnenolone; Rats; Succinates | 1970 |
Effect of cycloheximide on the ultrastructural changes produced by spironolactone and pregnenolone-16 alpha-carbonitrile in the rat liver.
Topics: Animals; Cycloheximide; Endoplasmic Reticulum; Female; Liver; Microscopy, Electron; Microsomes, Liver; NADP; Nitriles; Pregnenolone; Rats; Spironolactone | 1971 |
The effect of inhibitors of protein synthesis on cholesterol side-chain cleavage in the mitochondria of luteinized rat ovaries.
Topics: Androstenols; Animals; Carbon Radioisotopes; Chloramphenicol; Cholesterol; Chorionic Gonadotropin; Cycloheximide; Cytochrome P-450 Enzyme System; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Ketosteroids; Kinetics; Mitochondria; Nitriles; Ovary; Pregnenolone; Proteins; Puromycin; Rats | 1974 |
Induction of structural alterations in the preovulatory amphibian ovarian follicle by hormones.
Topics: Animals; Cells, Cultured; Cycloheximide; Depression, Chemical; Desoxycorticosterone; Estradiol; Estriol; Estrone; Female; Hormones; In Vitro Techniques; Micromanipulation; Ovarian Follicle; Pituitary Gland; Pregnenolone; Progesterone; Protein Biosynthesis; Puromycin; Rana pipiens; Testosterone | 1972 |
Action of progesterone and related steroids on oocyte maturation in Xenopus laevis. An in vitro study.
Topics: Animals; Cortisone; Cycloheximide; Dactinomycin; Female; Hydrocortisone; In Vitro Techniques; Meiosis; Ovum; Prednisolone; Pregnenolone; Progesterone; Protein Biosynthesis; Puromycin; RNA; Xenopus | 1972 |
Spectral properties of rat adrenal-mitochondrial cytochrome P-450.
Topics: Adrenal Glands; Animals; Binding Sites; Carbon Radioisotopes; Cattle; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Ethyl Ethers; Female; Hydrogen-Ion Concentration; Male; Mitochondria; Pregnenolone; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Stress, Physiological; Time Factors | 1974 |
The influence of temperature on steroidogenesis in the rat testis.
Topics: Alanine; Animals; Carbon Isotopes; Cholesterol; Cycloheximide; Glucose; In Vitro Techniques; Lysine; Male; Pregnenolone; Progesterone; Protein Biosynthesis; Rats; Steroids; Temperature; Testis; Testosterone | 1968 |
Rat adrenal cycloheximide-sensitive factors and phospholipids in the control of acute steroidogenesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cell-Free System; Cycloheximide; Hot Temperature; Male; Mitochondria; Phospholipids; Pregnenolone; Progesterone; Proteins; Rats | 1984 |
Mechanisms subserving the trophic actions of insulin on ovarian cells. In vitro studies using swine granulosa cells.
Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Female; Granulosa Cells; Insulin; Insulin Antagonists; NADPH-Ferrihemoprotein Reductase; Pregnenolone; Progesterone; Protein Biosynthesis; RNA; Swine | 1983 |
Actions of luteinizing hormone on protein phosphorylation and steroidogenesis in tumor Leydig cells.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Cycloheximide; Cytochalasin B; Cytosol; Leydig Cell Tumor; Luteinizing Hormone; Microsomes; Phosphoproteins; Phosphorylation; Pregnenolone; Protein Biosynthesis; Protein Kinases; Steroids | 1984 |
Non-esterified cholesterol-rich adrenal lipid fractions. Preparation, properties and preferential utilization for cholesterol side-chain cleavage by corticotropin-stimulated adrenal mitochondria.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcium; Centrifugation, Density Gradient; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, Gel; Cycloheximide; Cytosol; In Vitro Techniques; Lipid Metabolism; Lipids; Male; Mitochondria; Pregnenolone; Rats | 1980 |
Polyphosphoinositides:stimulator of mitochondrial cholesterol side chain cleavage and possible identification as an adrenocorticotropin-induced, cycloheximide-sensitive, cytosolic, steroidogenic factor.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Cytosol; Detergents; Male; Mitochondria; Oxidoreductases; Phosphatidylinositols; Phospholipids; Pregnenolone; Rats; Structure-Activity Relationship | 1980 |
Sterol carrier protein2. Identification of adrenal sterol carrier protein2 and site of action for mitochondrial cholesterol utilization.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carrier Proteins; Cholesterol; Cycloheximide; Cytosol; Electrophoresis, Polyacrylamide Gel; Immunoelectrophoresis; Kinetics; Liver; Male; Microsomes, Liver; Mitochondria; Plant Proteins; Pregnenolone; Rats; Rats, Inbred Strains; Sterols | 1983 |
Identification of the cycloheximide-sensitive site in angiotensin-stimulated aldosterone synthesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Cattle; Cycloheximide; Female; In Vitro Techniques; Mitochondria; Phosphatidylinositols; Pregnenolone | 1984 |
Sterol carrier protein2 (SCP2)-mediated transfer of cholesterol to mitochondrial inner membranes.
Topics: Adrenal Glands; Animals; Carrier Proteins; Cholesterol; Cycloheximide; Intracellular Membranes; Kinetics; Malate Dehydrogenase; Male; Mitochondria; NADH Dehydrogenase; Plant Proteins; Pregnenolone; Rats; Rats, Inbred Strains; Sterols | 1984 |
Control of steroidogenesis in rat corpus luteum: the rate of access of cholesterol to the active site of the cholesterol side-chain cleavage enzyme.
Topics: Animals; Binding Sites; Calcium; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Corpus Luteum; Cycloheximide; Female; Luteinizing Hormone; Mitochondria; Oxidoreductases; Pregnenolone; Rats; Rats, Inbred Strains | 1981 |
The effect of ether stress and cycloheximide treatment on cholesterol binding and enzyme turnover of adrenal cortical cytochrome P450scc.
Topics: Adrenal Cortex; Aminoglutethimide; Animals; Cholesterol; Cycloheximide; Cytochrome P-450 Enzyme System; Ether; Female; Mitochondria; Oxygen; Pregnenolone; Rats; Rats, Inbred Strains; Spectrophotometry; Stress, Physiological | 1982 |
Lutropin increases phosphorylation of a 33 000-dalton ribosomal protein in rat tumour Leydig cells.
Topics: Animals; Cycloheximide; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Pregnenolone; Puromycin; Rats; Rats, Inbred Strains; Ribosomal Proteins; Subcellular Fractions | 1982 |
Modulatory mechanisms of cyclic AMP-stimulated steroid content in rat brain cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adrenalectomy; Animals; Benzodiazepinones; Bucladesine; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; In Vitro Techniques; Isoquinolines; Male; Orchiectomy; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear | 1994 |
Thyroid hormone regulation of perch ovarian 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase activity: involvement of a 52-kDa protein.
Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, Thin Layer; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Molecular Weight; Multienzyme Complexes; Ovarian Follicle; Perches; Pregnenolone; Progesterone; Progesterone Reductase; Radioimmunoassay; Rats; Scintillation Counting; Steroid Isomerases; Triiodothyronine | 1999 |
Pregnenolone sulfate, a naturally occurring excitotoxin involved in delayed retinal cell death.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cycloheximide; Dehydroepiandrosterone Sulfate; DNA Fragmentation; Estradiol; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Neurotoxins; Pregnenolone; Progesterone; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Retina; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances | 2000 |
Identification of maturation-inducing steroid in a freshwater perch Anabas testudineus and differential responses of intact follicles and denuded oocytes to cyclic AMP in oocyte maturation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Hydroxyprogesterones; Oocytes; Organ Culture Techniques; Ovarian Follicle; Perches; Pregnenolone | 2000 |
Corticosterone enhances adrenocorticotropin-induced calcium signals in bovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Calcium; Cattle; Cell Membrane; Cells, Cultured; Corticosterone; Cycloheximide; Microscopy, Fluorescence; Pregnenolone; Serum Albumin, Bovine; Signal Transduction | 2003 |
Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bilirubin; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunoblotting; Immunohistochemistry; Isoquinolines; Membrane Proteins; Metalloporphyrins; Mice; Pregnenolone; Protoporphyrins; RNA, Messenger; Stimulation, Chemical; Sulfonamides; Thiobarbituric Acid Reactive Substances; Time Factors; Tumor Cells, Cultured | 2004 |
Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain; Central Nervous System Depressants; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Ethanol; GABA Agents; Gene Expression Regulation; Glucocorticoids; Hypophysectomy; Imidazoles; Immunoglobulin G; Immunoprecipitation; Isoquinolines; Male; Melphalan; Phosphoproteins; Pregnanolone; Pregnenolone; Protein Synthesis Inhibitors; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Steroids | 2010 |