Page last updated: 2024-08-17

cycloheximide and paclitaxel

cycloheximide has been researched along with paclitaxel in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.71)18.7374
1990's13 (37.14)18.2507
2000's14 (40.00)29.6817
2010's6 (17.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barrows, LR; Ireland, CM; Kokoshka, JM1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Dembitsky, VM1
Janjic, J; Kozmin, SA; Kron, SJ; Sabharwal, SS; Schumacker, PT; Suzuki, M; Ulanovskaya, OA1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Alvarado, C; Cerbón, MA; Díaz, E; González-Sánchez, I; Guzmán, Á; Martínez-Urbina, MA; Martínez-Zuñiga, EC; Quintero, A; Solano, JD; Vilchis-Reyes, MA1
Addo, EM; Anaya-Eugenio, GD; Carcache de Blanco, EJ; Ezzone, N; Henkin, JM; Kinghorn, AD; Ninh, TN; Ren, Y; Soejarto, DD1
Chen, LB; Ferguson, M; Lee, C1
Marzella, L; Yu, QC1
Fabbi, M; Gangemi, RM; Marchetti, C; Severi, AB; Tiso, M1
Aizu-Yokota, E; Sato, Y; Susaki, A1
Gerok, W; Häussinger, D; Stoll, B; vom Dahl, S1
Cook, JA; Fisher, J; Liebmann, J; Mitchell, JB; Teague, D1
Park, J; Rikihisa, Y; Zhang, Y1
Grocholová, R; Jílek, F; Petr, J; Rozinek, J1
Daxenbichler, G; Lang, T; Marth, C; Müller-Holzner, E; Widschwendter, M1
Liu, D; Mori, H; Sy, MS; Zhang, D1
Das, KC; White, CW1
Cuttitta, F; Elsasser, T; Salkowski, CA; Vogel, SN; Zaks-Zilberman, M1
Goto, J; Hazeki, N; Kanazawa, I; Nakamura, K1
Choi, BM; Chung, HT; Kim, TY; Pae, HO; Yoo, JC1
Field, CM; Foe, VE; Odell, GM1
Albertini, DF; Carabatsos, MJ; Combelles, CM; Messinger, SM1
Choi, SH; Chun, BG; Chun, YS; Kang, H; Kang, SW; Min, BH; Park, IS; Shin, KH1
Brichese, L; Chadebech, P; Truchet, I; Valette, A1
Horwitz, SB; Yang, CP1
Cantoni, C; Daga, A; Lunardi, C; Millo, R; Oliveri, M; Puccetti, A1
Clark, OH; Duh, QY; Hyun, WC; Lobo, M; Park, JW; Wong, MG1
Abbro, L; Dini, L; Lanubile, R1
Jordan-Sciutto, KL; Koike, MA; Kopp, AS; Morgan, KL; Strachan, GD1
Bodo, J; Duraj, J; Rauko, P; Sedlak, J; Sulikova, M1
Armstrong, SR; Guo, B; Hembruff, SL; Kalatskaya, I; Lanner, C; Parissenti, AM; Reed, K; Sprowl, JA; Stein, L; Tam, A1
Choi, JH; Jin, Y; Kim, ST; Lee, SK; Liu, L; Yim, H1

Reviews

1 review(s) available for cycloheximide and paclitaxel

ArticleYear
Bioactive peroxides as potential therapeutic agents.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Peroxides

2008

Other Studies

34 other study(ies) available for cycloheximide and paclitaxel

ArticleYear
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured

1996
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.
    Nature chemical biology, 2008, Volume: 4, Issue:7

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Design; Electron Transport Complex III; Humans; Macrolides; Mitochondrial Membranes; Models, Molecular; Molecular Structure; Saccharomyces cerevisiae; Sesquiterpenes

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
The products of the reaction between 6-amine-1,3-dimethyl uracil and bis-chalcones induce cytotoxicity with massive vacuolation in HeLa cervical cancer cell line.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Chalcones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; Uracil

2013
Caspase-Dependent Apoptosis in Prostate Cancer Cells and Zebrafish by Corchorusoside C from Streptocaulon juventas.
    Journal of natural products, 2019, 06-28, Volume: 82, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apocynaceae; Apoptosis; Caspases; Cell Line, Tumor; Humans; I-kappa B Kinase; Male; Molecular Structure; Poly (ADP-Ribose) Polymerase-1; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrans; Vietnam; Zebrafish

2019
Construction of the endoplasmic reticulum.
    The Journal of cell biology, 1989, Volume: 109, Issue:5

    Topics: Actins; Alkaloids; Animals; Carbocyanines; Cell Line; Cycloheximide; Cytochalasin B; Endoplasmic Reticulum; Fluorescent Antibody Technique; Fluorescent Dyes; Intermediate Filaments; Microtubules; Nocodazole; Paclitaxel; Staining and Labeling

1989
Modification of lysosomal proteolysis in mouse liver with taxol.
    The American journal of pathology, 1986, Volume: 122, Issue:3

    Topics: Alkaloids; Animals; Cycloheximide; Glucagon; Liver; Lysosomes; Male; Mice; Mice, Inbred Strains; Paclitaxel; Peptide Hydrolases; Subcellular Fractions

1986
Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:5

    Topics: Apoptosis; Cycloheximide; Drug Resistance; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Leukemia; Microscopy, Electron; Paclitaxel; Thymidine; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1995
Natural estrogens induce modulation of microtubules in Chinese hamster V79 cells in culture.
    Cancer research, 1995, May-01, Volume: 55, Issue:9

    Topics: Animals; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; Cycloheximide; Cytoplasm; Dactinomycin; Estradiol; Estrogens; Microtubules; Paclitaxel

1995
Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures.
    The Biochemical journal, 1995, Jun-01, Volume: 308 ( Pt 2)

    Topics: Animals; Bile; Cell Size; Cells, Cultured; Colchicine; Cycloheximide; Cytochalasin B; Demecolcine; Endopeptidases; In Vitro Techniques; Liver; Male; Microtubules; Paclitaxel; Phenylalanine; Rats; Rats, Wistar; Taurocholic Acid; Water-Electrolyte Balance

1995
Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).
    Anti-cancer drugs, 1994, Volume: 5, Issue:3

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Cycle; Cell Death; Cycloheximide; DNA, Neoplasm; Drug Interactions; Flow Cytometry; Humans; Lung Neoplasms; Mitotic Index; Neoplasm Proteins; Paclitaxel; Tumor Cells, Cultured

1994
Inhibition of infection of macrophages with Ehrlichia risticii by cytochalasins, monodansylcadaverine, and taxol.
    Infection and immunity, 1994, Volume: 62, Issue:11

    Topics: Actin Cytoskeleton; Animals; Cadaverine; Clathrin; Colchicine; Cycloheximide; Cytochalasins; Ehrlichia; Ehrlichiosis; Endocytosis; Female; In Vitro Techniques; Macrophages, Peritoneal; Mice; Microtubules; Nitrites; Paclitaxel; Reactive Oxygen Species

1994
Microtubule rearrangement during in vitro maturation of pig oocytes. Effect of cycloheximide.
    Reproduction, nutrition, development, 1995, Volume: 35, Issue:6

    Topics: Animals; Chromatin; Cycloheximide; Female; Meiosis; Microtubules; Nuclear Envelope; Oocytes; Paclitaxel; Protein Synthesis Inhibitors; Swine

1995
Effects of Taxol on choriocarcinoma cells.
    American journal of obstetrics and gynecology, 1995, Volume: 173, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Etoposide; Female; Humans; Methotrexate; Paclitaxel; Pregnancy; Tumor Cells, Cultured; Uterine Neoplasms

1995
Binding of CD44 to hyaluronic acid can be induced by multiple signals and requires the CD44 cytoplasmic domain.
    Cellular immunology, 1996, Nov-25, Volume: 174, Issue:1

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; CD3 Complex; Colchicine; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin D; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Humans; Hyaluronan Receptors; Hyaluronic Acid; Ionomycin; Ionophores; Jurkat Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Paclitaxel; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Transfection

1996
Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: Adenocarcinoma; Antineoplastic Agents; Binding, Competitive; Cell Nucleus; Cycloheximide; Dactinomycin; Daunorubicin; Dexamethasone; Doxorubicin; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; NF-kappa B; Oligodeoxyribonucleotides; Paclitaxel; Protein Kinase C; Transcription Factors; Tumor Cells, Cultured; Vincristine

1997
Induction of adrenomedullin mRNA and protein by lipopolysaccharide and paclitaxel (Taxol) in murine macrophages.
    Infection and immunity, 1998, Volume: 66, Issue:10

    Topics: Adrenomedullin; Animals; Cycloheximide; Female; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Mimicry; Paclitaxel; Peptides; Protein Synthesis Inhibitors; RNA, Messenger; Tissue Distribution; Vasodilator Agents

1998
Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
    Biochemical and biophysical research communications, 1999, Mar-16, Volume: 256, Issue:2

    Topics: Animals; Blotting, Western; Cell Nucleus; COS Cells; Cycloheximide; Cytochalasin D; Cytoplasm; Exons; Humans; Huntingtin Protein; Huntington Disease; Molecular Weight; Nerve Tissue Proteins; Nocodazole; Nuclear Proteins; Paclitaxel; Peptide Fragments; Peptides; Protein Binding; Recombinant Fusion Proteins; Time Factors; Transfection; Tunicamycin

1999
Protective effects of glucocorticoids on taxol-induced cytotoxicity in human leukemia HL-60 cells.
    Immunopharmacology and immunotoxicology, 1999, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Colchicine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Glucocorticoids; HL-60 Cells; Humans; Paclitaxel

1999
Microtubules and mitotic cycle phase modulate spatiotemporal distributions of F-actin and myosin II in Drosophila syncytial blastoderm embryos.
    Development (Cambridge, England), 2000, Volume: 127, Issue:9

    Topics: Actins; Animals; Blastoderm; Centrosome; Cycloheximide; Cytoskeleton; Drosophila; Fluorescent Dyes; Giant Cells; Image Processing, Computer-Assisted; Kinesins; Microscopy, Confocal; Microscopy, Video; Microtubules; Mitosis; Myosins; Paclitaxel

2000
Sorting and reorganization of centrosomes during oocyte maturation in the mouse.
    Microscopy research and technique, 2000, Jun-01, Volume: 49, Issue:5

    Topics: Anaphase; Animals; Antigens; Centrosome; Cycloheximide; Cytochalasin D; Dyneins; Female; Gonadotropins; Meiosis; Metaphase; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Scanning Probe; Microtubules; Nocodazole; Oocytes; Paclitaxel; Spindle Apparatus; Time Factors; Tubulin; Vanadates

2000
Cytoprotective effect of arginine deiminase on taxol-induced apoptosis in DU145 human prostate cancer cells.
    Molecules and cells, 2000, Jun-30, Volume: 10, Issue:3

    Topics: Amino Acid Sequence; Animals; Apoptosis; Arginine; Astrocytes; Cell Line; Culture Media, Conditioned; Cycloheximide; Cytoprotection; DNA Fragmentation; G1 Phase; Humans; Hydrolases; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; Molecular Sequence Data; Nitric Oxide; Paclitaxel; Prostatic Neoplasms; Protein Synthesis Inhibitors; Rats; Sequence Alignment; Sertoli Cells; Tumor Cells, Cultured

2000
Up-regulation of cdc2 protein during paclitaxel-induced apoptosis.
    International journal of cancer, 2000, Sep-15, Volume: 87, Issue:6

    Topics: 2-Aminopurine; Antimetabolites; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Cycloheximide; DNA; Enzyme Activation; G2 Phase; Humans; Paclitaxel; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation

2000
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform.
    Cancer research, 2000, Sep-15, Volume: 60, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents, Phytogenic; Carcinoma; Cyanogen Bromide; Cycloheximide; Drug Interactions; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Flavonoids; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Microtubules; Paclitaxel; Peptide Fragments; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-raf; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; Tyrosine

2000
DNase I mediates internucleosomal DNA degradation in human cells undergoing drug-induced apoptosis.
    European journal of immunology, 2001, Volume: 31, Issue:3

    Topics: Apoptosis; Cell Nucleus; Cell Survival; Cycloheximide; Dactinomycin; Deoxyribonuclease I; DNA; DNA Fragmentation; Etoposide; fas Receptor; Gene Targeting; Humans; Jurkat Cells; Kinetics; Nucleosomes; Paclitaxel; Transfection; Tumor Cells, Cultured

2001
Modulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by chemotherapy in thyroid cancer cell lines.
    Thyroid : official journal of the American Thyroid Association, 2003, Volume: 13, Issue:12

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line, Tumor; Chromans; Cycloheximide; Drug Synergism; Humans; Membrane Glycoproteins; Paclitaxel; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Thiazolidinediones; Thyroid Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Troglitazone; Tumor Necrosis Factor-alpha

2003
Ultrastructural study of apoptotic U937 [corrected] cells treated with different pro-apoptotic substances.
    Microscopy research and technique, 2004, May-01, Volume: 64, Issue:1

    Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Apoptosis; Cycloheximide; Humans; Hydrogen Peroxide; Oxidants; Paclitaxel; Protein Synthesis Inhibitors; Puromycin; U937 Cells

2004
Chemokine- and neurotrophic factor-induced changes in E2F1 localization and phosphorylation of the retinoblastoma susceptibility gene product (pRb) occur by distinct mechanisms in murine cortical cultures.
    Experimental neurology, 2005, Volume: 193, Issue:2

    Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Cycle Proteins; Cells, Cultured; Cerebral Cortex; Chemokine CCL5; Chemokines; Cycloheximide; DNA; DNA-Binding Proteins; Drug Interactions; E2F Transcription Factors; E2F1 Transcription Factor; Embryo, Mammalian; Fatty Acids, Unsaturated; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Hydrogen Peroxide; Indoles; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microtubule-Associated Proteins; Nerve Growth Factors; Paclitaxel; Phosphorylation; Pregnancy; Protein Synthesis Inhibitors; Retinoblastoma Protein; Transcription Factors

2005
Diverse resveratrol sensitization to apoptosis induced by anticancer drugs in sensitive and resistant leukemia cells.
    Neoplasma, 2006, Volume: 53, Issue:5

    Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Busulfan; Cell Cycle; Cell Line, Tumor; Cycloheximide; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gemcitabine; Humans; Leukemia; Paclitaxel; Resveratrol; Stilbenes

2006
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.
    Breast cancer research : BCR, 2012, Jan-06, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Cycloheximide; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; MCF-7 Cells; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Protein Synthesis Inhibitors; Proteolysis; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Taxoids; Transcriptional Activation; Tumor Necrosis Factor-alpha

2012
ATM kinase promotes both caspase-8 and caspase-9 activation during TNF-α-induced apoptosis of HeLa cells.
    FEBS letters, 2014, Mar-18, Volume: 588, Issue:6

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Caspase 8; Caspase 9; Cell Cycle Proteins; Cycloheximide; DNA Damage; Enzyme Activation; HeLa Cells; Humans; Mitochondria; Nuclear Proteins; Paclitaxel; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2014