cycloheximide has been researched along with okadaic acid in 102 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 67 (65.69) | 18.2507 |
| 2000's | 31 (30.39) | 29.6817 |
| 2010's | 3 (2.94) | 24.3611 |
| 2020's | 1 (0.98) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, S; Aggarwal, BB; Totpal, K | 1 |
| Bereta, J; Bereta, M; Coffman, FD; Cohen, MC; Cohen, S | 1 |
| Datta, R; Hass, R; Kharbanda, S; Kufe, D; Nakamura, T; Rubin, E | 1 |
| Calderwood, SK; Mannheim-Rodman, LA; Price, BD | 1 |
| Kehrl, JH; Rieckmann, P; Thévenin, C | 1 |
| Goris, J; Huchon, D; Jessus, C; Merlevede, W; Ozon, R; Rime, H | 1 |
| Barratt, MJ; Mahadevan, LC; Willis, AC | 1 |
| Fujiwara, C; Mochizuki, N; Oda, T; Ohta, M; Sagara, J; Shimizu, N; Utiyama, H | 1 |
| Hunter, T; Nishimoto, T; Nishitani, H; Ohtsubo, M; Pines, J; Sugimura, T; Yamashita, K; Yasuda, H; Yasumoto, K | 1 |
| Carter, V; Gale, M; Parsons, M | 1 |
| Herrington, J; Iwata, M; Zager, RA | 1 |
| Aggarwal, BB; Chan, H; Higuchi, M; Singh, S | 1 |
| Antalis, TM; Reeder, JA | 1 |
| Azzi, A; Boscoboinik, D; Galeotti, T | 1 |
| Eppig, JJ; Hampl, A | 1 |
| Ilvonen, E; Kähäri, VM; Uitto, J; Westermarck, J | 1 |
| Barrio, S; Baugnet-Mahieu, L; de Saint-Georges, L; Jacquet, P | 1 |
| Avvedimento, EV; Gottesman, ME; Grieco, D | 1 |
| Forchhammer, J; Jensen, PO; Larsen, JK; Lund, LR; Skouv, J | 1 |
| Fujii, J; Ikeda, Y; Miyoshi, E; Nakata, T; Taniguchi, N | 1 |
| Banting, G; Horn, M | 1 |
| Aunis, D; Haby, C; Zwiller, J | 1 |
| Hamilton, TA; Tebo, JM | 1 |
| Anderson, KC; Chauhan, D; Kharbanda, SM; Kufe, DW; Sukhatme, VP; Uchiyama, H | 1 |
| Cavadore, JC; Gavin, AC; Schorderet-Slatkine, S | 1 |
| Favre, B; Hemmings, BA; Kiefer, B; Lee, JS; Nagamine, Y | 1 |
| Deckers, CL; Lyons, AB; Maddy, AH; Samuel, K; Sanderson, A | 1 |
| Hou, MC; Lai, YK; Lee, WC; Shen, CH | 1 |
| Guerrier, P; Kalous, J; Kubelka, M; Motlik, J; Rimkevicova, Z | 1 |
| Adler, V; Franklin, CC; Kraft, AS; Unlap, T | 1 |
| Mufson, RA; Rao, P | 1 |
| Matsui, T; Yamaguchi, M | 2 |
| Babu, SV; Ramaiah, KV | 1 |
| Bowden, GT; Rosenberger, SF | 1 |
| Nirodi, CS; Padmanaban, G; Prabhu, L; Ram, N; Sultana, S | 1 |
| Lin, J; Raffaniello, RD; Raufman, JP | 1 |
| Kopf, GS; Moos, J; Schultz, RM | 1 |
| Berg, DK; Romano, SJ; Rothhut, B; Vijayaraghavan, S | 1 |
| Fukuhara, M; Kurose, K; Tohkin, M | 1 |
| Ghosh, S; Paweletz, N; Schroeter, D | 1 |
| Choi, JY; Kim, IS; Lee, BH; Park, RW; Ryoo, HM; Sohn, KY | 1 |
| Ilvonen, E; Kähäri, VM; Westermarck, J | 1 |
| Lévesque, JT; Sirard, MA | 1 |
| Grocholová, R; Jílek, F; Petr, J; Rozinek, J | 1 |
| Gavin, AC; Schorderet-Slatkine, S | 1 |
| Rieber, M; Rieber, MS | 1 |
| Horie, S; Ishii, H; Kohno, M; Maeda, H; Nakai, T; Oida, K | 1 |
| Chen, G; Hawver, DB; Manji, HK; Potter, WZ; Yuan, P | 1 |
| Marks, PA; Merchant, JL; Mortensen, ER; Shiotani, A | 1 |
| Pinna, C; Rossini, GP; Viviani, R | 1 |
| Alemany, S; Fernández-Renart, M; Lisbona, C | 1 |
| Baysal, K; Guo, YL; Kang, B; Williamson, JR; Yang, LJ | 1 |
| Hanson, ES; Leibold, EA | 1 |
| Fox, ES; Leingang, KA | 1 |
| Mijovic, JE; Olson, DM; Zakar, T | 1 |
| Eppig, JJ; Hampl, A; Knowles, BB; Oh, B; Solter, D | 1 |
| Berger, S; León, J; Rojo, E; Sánchez-Serrano, JJ; Titarenko, E; Vancanneyt, G | 1 |
| Fass, U; Huizar, I; Li, DW; Spector, A | 1 |
| El Khissiin, A; Laios, I; Larsimont, D; Leclercq, G; Legros, N; Querton, G; Seo, HS | 1 |
| Hisanaga, S; Ishiguro, K; Kishimoto, T; Nagai, Y; Onuki, R; Saito, T | 1 |
| Cañelles, M; Cuadrado, MA; Delgado, MD; Frade, P; León, J; Lerga, A; Richard, C | 1 |
| Hukovic, N; Khare, S; Kumar, U; Patel, YC; Rocheville, M; Sasi, R | 1 |
| Haneji, T; Kobayashi, S; Morimoto, H; Morimoto, Y; Ohba, T | 1 |
| Haneji, T; Kido, H; Kobayashi, S; Morimoto, H; Morimoto, Y; Ohba, T | 1 |
| Chen, XL; Dean, RG; Hausman, GJ | 1 |
| Dudler, R; Freydl, E; Granado, J; Hassa, P; Wäspi, U | 1 |
| Tatemoto, H; Terada, T | 1 |
| Hong, HN; Kim, DH; Lee, JH; Park, HS | 1 |
| Dumont, JE; Galand, P; Lecocq, R; Mosselmans, R; Robaye, B; Suarez-Huerta, N | 1 |
| Hara, K; Koizumi, N; Kusano, T; Sano, H; Yagi, M | 1 |
| Cook, JA; Ferlito, M; Fernando, AN; Fernando, LP; Halushka, PV | 1 |
| Bishop, KJ; Hall, TC; Li, G | 1 |
| Bringuier, AF; Feldmann, G; Lamboley, C | 1 |
| Fujiki, Y; Ito, M; Nishida, I; Watanabe, A | 1 |
| Camandola, S; Mattson, MP; Poli, G | 1 |
| Antonicelli, F; Donaldson, K; Hirani, N; MacNee, W; Parmentier, M; Rahman, I | 1 |
| Bonk, A; Lai, L; Prather, RS; Schatten, H; Sun, QY | 1 |
| Roepstorff, K; Stahlhut, M; Thomsen, P; van Deurs, B | 1 |
| Hirasawa, E; Yamagata, H; Yoshida, I | 1 |
| Louandre, C; Marcheux, V; Mazière, C; Mazière, JC | 1 |
| Gimbrone, MA; Masuda, J; Ochi, H | 1 |
| Baltz, JM; Collins, JL; Petrunewich, MA; Phillips, KP | 1 |
| Hong, HN; Kim, D; Lee, JH; Suh, J; Yoon, SY | 1 |
| Baudouin, E; Hirt, H; Jelinek, H; Jonak, C; Liwosz, A; Meskiene, I; Rodriguez, PL; Schweighofer, A | 1 |
| Hu, YX; Li, JY; Liu, XF; Wang, YX | 1 |
| Maruyama-Nakashita, A; Nakamura, Y; Takahashi, H; Watanabe-Takahashi, A; Yamaya, T | 1 |
| Antonicelli, F; Brown, D; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Chen, DY; Peng, A; Sun, QY; Tan, X; Tang, YZ; Wang, YC | 1 |
| Date, DA; Kaur, H; Stiff, AC; Taylor, WR | 1 |
| Bailey, KJ; Gray, JE; Leegood, RC; Walker, RP | 1 |
| Ramana, CV; Rishi, AK; Wali, A; Zhang, L | 1 |
| Agrawal, GK; Cho, K; Jeong, SH; Jung, YH; Jwa, NS; Kim, JA; Kim, SH; Kubo, A; Lee, MO; Rakwal, R; Shibato, J; Shim, J; Tamogami, S | 1 |
| Boon-Unge, K; Govitrapong, P; Yu, Q; Zhou, A; Zhou, J; Zou, T | 1 |
| Cohen, IS; Doronin, SV; Potapova, IA | 1 |
| Hivert, V; Pierre, J; Raingeaud, J | 1 |
| Charlson, AT; Wattenberg, EV; Zeliadt, NA | 1 |
| Arawaka, S; Fukushima, S; Hara, S; Kato, T; Koyama, S; Machiya, Y; Sakamoto, M; Sato, H | 1 |
| Chen, KF; Chu, PY; Hsieh, FS; Huang, CT; Huang, TT; Hung, MH; Ko, PS; Liu, CY; Shiau, CW; Tsai, WC; Wang, WL; Yu, YB | 1 |
| Cherubin, P; Quiñones, B; Teter, K | 1 |
| Balaban, PM; Maltsev, AV | 1 |
102 other study(ies) available for cycloheximide and okadaic acid
| Article | Year |
|---|---|
Phosphatase inhibitors modulate the growth-regulatory effects of human tumor necrosis factor on tumor and normal cells.
Topics: Animals; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Ethers, Cyclic; Fibroblasts; Humans; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Tumor Necrosis Factor-alpha; Vanadates | 1992 |
Inhibition of basal and tumor necrosis factor-enhanced binding of murine tumor cells to murine endothelium by transforming growth factor-beta 1.
Topics: Animals; Calcium; Cell Adhesion; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethers, Cyclic; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1992 |
Regulation of c-jun expression during induction of monocytic differentiation by okadaic acid.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Ethers, Cyclic; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Isoquinolines; Lymphoma, Large B-Cell, Diffuse; Male; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells; Okadaic Acid; Piperazines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Brefeldin A, thapsigargin, and AIF4- stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis.
Topics: 3T3 Cells; Aluminum; Aluminum Compounds; Animals; Brefeldin A; Carrier Proteins; Cell Hypoxia; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum Chaperone BiP; Ethers, Cyclic; Fluorides; Fluorine; Genistein; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Isoflavones; Membrane Proteins; Mice; Molecular Chaperones; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Terpenes; Thapsigargin | 1992 |
Okadaic acid is a potent inducer of AP-1, NF-kappa B, and tumor necrosis factor-alpha in human B lymphocytes.
Topics: B-Lymphocytes; Cell Division; Cells, Cultured; Cycloheximide; Ethers, Cyclic; Genes, fos; Genes, jun; Humans; Immunoglobulins; NF-kappa B; Okadaic Acid; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tumor Necrosis Factor-alpha | 1992 |
Characterization of MPF activation by okadaic acid in Xenopus oocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Cyclic AMP; Cycloheximide; Ethers, Cyclic; Female; Growth Substances; Immunohistochemistry; Maturation-Promoting Factor; Microinjections; Microtubules; Nuclear Envelope; Okadaic Acid; Oocytes; Phosphoric Monoester Hydrolases; Phosphorylation; Xenopus laevis | 1990 |
Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors.
Topics: Amanitins; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chromatin; Cycloheximide; Dactinomycin; Ethers, Cyclic; Growth Substances; Histones; Mice; Mice, Inbred C3H; Molecular Sequence Data; Nucleosomes; Okadaic Acid; Phosphates; Phosphopeptides; Phosphorylation; Protein Synthesis Inhibitors; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Differentiation; Cycloheximide; DNA; Ethers, Cyclic; Humans; Macrophages; Molecular Sequence Data; Okadaic Acid; Phosphorylation; RNA, Messenger; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1991 |
Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells.
Topics: Animals; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle; Cell Line; Chromosomes; Cricetinae; Cyclins; Cycloheximide; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Intracellular Signaling Peptides and Proteins; Mesocricetus; Mitosis; Okadaic Acid; Phosphoprotein Phosphatases; Proteins; Translocation, Genetic | 1990 |
Cell cycle-specific induction of an 89 kDa serine/threonine protein kinase activity in Trypanosoma brucei.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Catechols; Cell Cycle; Cell Division; Cycloheximide; DNA; Enzyme Induction; Ethers, Cyclic; Flow Cytometry; Genistein; Isoflavones; Isoquinolines; Molecular Weight; Nitriles; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Denaturation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Staurosporine; Trypanosoma brucei brucei; Tyrosine; Tyrphostins | 1994 |
Protein synthesis inhibition induces cytoresistance in cultured human proximal tubular (HK-2) cells.
Topics: Adenosine Triphosphate; Antimycin A; Cell Death; Cell Line; Cycloheximide; Deoxyglucose; Drug Interactions; Ethers, Cyclic; Humans; Immunoblotting; Kidney Tubules, Proximal; Kinetics; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Trichothecenes; Vanadates | 1995 |
Protease inhibitors differentially regulate tumor necrosis factor-induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Base Sequence; Cell Differentiation; Cycloheximide; Cytotoxicity, Immunologic; DNA Damage; Ethers, Cyclic; Gene Expression Regulation, Leukemic; Humans; Isoquinolines; Leukemia, Myeloid; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Okadaic Acid; Piperazines; Protease Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Butyrate regulates gene expression of the plasminogen activating system in colon cancer cells.
Topics: Adenocarcinoma; Butyrates; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Down-Regulation; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; In Vitro Techniques; Okadaic Acid; Plasminogen Activator Inhibitor 1; Protein Kinase C; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1995 |
Regulation of the TNF-alpha receptor in human osteosarcoma cells: role of microtubules and of protein kinase C.
Topics: Alkaloids; Cell Membrane; Cycloheximide; Ethers, Cyclic; Humans; Kinetics; Microtubules; Naphthalenes; Okadaic Acid; Osteosarcoma; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine | 1993 |
Translational regulation of the gradual increase in histone H1 kinase activity in maturing mouse oocytes.
Topics: Animals; Cyclins; Cycloheximide; Ethers, Cyclic; Female; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Mice; Mice, Inbred C57BL; Okadaic Acid; Oocytes; Oogenesis; Protamine Kinase; Protein Biosynthesis | 1995 |
Suppression of elastin gene expression in dermal fibroblasts by protein phosphatase inhibitor okadaic acid.
Topics: Adult; Animals; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Elastin; Ethers, Cyclic; Gene Expression Regulation; Humans; Male; Mice; Mice, Transgenic; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1995 |
Morphological effects of caffeine, okadaic acid and genistein in one-cell mouse embryos blocked in G2 by X-irradiation.
Topics: Animals; Blastocyst; Caffeine; CDC2 Protein Kinase; Cyclins; Cycloheximide; Ethers, Cyclic; G2 Phase; Genistein; Isoflavones; Mesothelin; Mice; Mice, Inbred BALB C; Okadaic Acid; Protein Synthesis Inhibitors; Zygote | 1995 |
A role for cAMP-dependent protein kinase in early embryonic divisions.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Division; Chromatography, Affinity; Cyclic AMP-Dependent Protein Kinases; Cyclins; Cycloheximide; Embryo, Nonmammalian; Ethers, Cyclic; Female; Immunoblotting; Interphase; Macromolecular Substances; Maturation-Promoting Factor; Mitosis; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Proteins; Recombinant Fusion Proteins; Sea Urchins; Time Factors; Xenopus | 1994 |
Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle.
Topics: Cell Cycle; Cycloheximide; Down-Regulation; Ethers, Cyclic; Half-Life; Humans; Okadaic Acid; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1994 |
Induction of manganese superoxide dismutase mRNA by okadaic acid and protein synthesis inhibitors.
Topics: Animals; Anisomycin; Cell Line; Cycloheximide; Dactinomycin; Ethers, Cyclic; HeLa Cells; Humans; Okadaic Acid; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Cycloheximide; Ethers, Cyclic; Fluorescent Antibody Technique; Glycoproteins; Golgi Apparatus; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Okadaic Acid; Peptide Fragments; Rats | 1994 |
Okadaic acid induces activator protein 1 activity and immediate early gene transcription in rat pheochromocytoma cells. Mechanism of action.
Topics: Animals; Cycloheximide; Dactinomycin; Ethers, Cyclic; Genes, fos; Genes, Immediate-Early; Genes, jun; Okadaic Acid; PC12 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Rats; Transcription, Genetic | 1994 |
Okadaic acid stimulates inflammatory cytokine gene transcription in murine peritoneal macrophages.
Topics: Animals; Chemokine CXCL10; Chemokines, CXC; Cycloheximide; Cytokines; Ethers, Cyclic; Half-Life; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; NF-kappa B; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1994 |
Involvement of serum response element in okadaic acid-induced EGR-1 transcription in human T-cells.
Topics: Base Sequence; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cycloheximide; DNA-Binding Proteins; Early Growth Response Protein 1; Ethers, Cyclic; Gene Expression; Humans; Immediate-Early Proteins; Molecular Sequence Data; Okadaic Acid; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Restriction Mapping; RNA, Messenger; T-Lymphocytes; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Zinc Fingers | 1994 |
Histone H1 kinase activity, germinal vesicle breakdown and M phase entry in mouse oocytes.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle; Cycloheximide; Enzyme Activation; Ethers, Cyclic; Female; Glycogen Synthase Kinase 3; In Vitro Techniques; Meiosis; Mice; Mitosis; Okadaic Acid; Oocytes; Protamine Kinase; Protein Tyrosine Phosphatases | 1994 |
Okadaic acid-dependent induction of the urokinase-type plasminogen activator gene associated with stabilization and autoregulation of c-Jun.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; Binding Sites; Blotting, Southern; Blotting, Western; Cell Line; Chloramphenicol O-Acetyltransferase; Colchicine; Cycloheximide; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme Induction; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Genes, Regulator; Homeostasis; Kinetics; Marine Toxins; Molecular Sequence Data; Nuclear Proteins; Okadaic Acid; Oligodeoxyribonucleotides; Oxazoles; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-jun; Time Factors; Transcriptional Activation; Transfection; Urokinase-Type Plasminogen Activator | 1994 |
Alternative pathways of apoptosis induced by methylprednisolone and valinomycin analyzed by flow cytometry.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Cells, Cultured; Cycloheximide; DNA Damage; Ethers, Cyclic; Flow Cytometry; Imidazoles; In Vitro Techniques; Macrolides; Male; Methylprednisolone; Mice; Okadaic Acid; Thymus Gland; Valinomycin | 1993 |
Okadaic acid as an inducer of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Calcimycin; Carrier Proteins; Cycloheximide; Dactinomycin; Endoplasmic Reticulum Chaperone BiP; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; Glioma; Glycosylation; Heat-Shock Proteins; Molecular Chaperones; Neoplasm Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Processing, Post-Translational; Rats; Tumor Cells, Cultured | 1993 |
Okadaic acid accelerates germinal vesicle breakdown and overcomes cycloheximide- and 6-dimethylaminopurine block in cattle and pig oocytes.
Topics: Adenine; Animals; Cattle; Cycloheximide; Enzyme Activation; Ethers, Cyclic; Female; Maturation-Promoting Factor; Okadaic Acid; Oocytes; Protamine Kinase; Swine | 1993 |
Multiple signal transduction pathways mediate c-Jun protein phosphorylation.
Topics: Cell Line; Cycloheximide; Ethers, Cyclic; Humans; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Signal Transduction | 1993 |
Interleukin-3 inhibits cycloheximide induction of C-jun mRNA in human monocytes: possible role for a serine/threonine phosphatase.
Topics: Cycloheximide; Ethers, Cyclic; Homeostasis; Humans; Interleukin-3; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylase Phosphatase; Proto-Oncogene Proteins c-jun; RNA, Messenger | 1993 |
Zinc modulation of insulin-like growth factor's effect in osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Alkaloids; Animals; Carnosine; Cycloheximide; DNA; Drug Synergism; Enzyme Inhibitors; Ethers, Cyclic; Insulin; Insulin-Like Growth Factor I; Mice; Okadaic Acid; Organometallic Compounds; Osteoblasts; Protein Synthesis Inhibitors; Proteins; Staurosporine; Zinc; Zinc Compounds | 1995 |
Type 1 phosphatase inhibitors reduce the restoration of guanine nucleotide exchange activity of eukaryotic initiation factor 2B inhibited reticulocyte lysates rescued by hemin.
Topics: Animals; Cell-Free System; Cycloheximide; eIF-2 Kinase; Enzyme Inhibitors; Ethers, Cyclic; Eukaryotic Initiation Factor-2; GTP-Binding Proteins; Guanosine Diphosphate; Heme; Kinetics; Okadaic Acid; Pactamycin; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Rabbits; Reticulocytes | 1996 |
Okadaic acid stimulated TRE binding activity in a papilloma producing mouse keratinocyte cell line involves increased AP-1 expression.
Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cycloheximide; Dactinomycin; Dimethyl Sulfoxide; DNA; DNA-Binding Proteins; Ethers, Cyclic; Keratinocytes; Mice; Nuclear Proteins; Okadaic Acid; Protein Biosynthesis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Regulatory Factor X Transcription Factors; RNA, Messenger; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Involvement of synthesis and phosphorylation of nuclear protein factors that bind to the positive cis-acting element in the transcriptional activation of the CYP2B1/B2 gene by phenobarbitone in vivo.
Topics: 2-Aminopurine; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cycloheximide; Cytochrome P-450 Enzyme System; DNA; Enzyme Inhibitors; Ethers, Cyclic; Molecular Sequence Data; Nuclear Proteins; Okadaic Acid; Phenobarbital; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; RNA, Messenger; Steroid Hydroxylases; Transcription, Genetic | 1996 |
Calcineurin mediates calcium-induced potentiation of adenylyl cyclase activity in dispersed chief cells from guinea pig stomach. Further evidence for cross-talk between signal transduction pathways that regulate pepsinogen secretion.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin-Binding Proteins; Carbachol; Cells, Cultured; Cholecystokinin; Cholera Toxin; Cyclic AMP; Cycloheximide; Cyclosporine; Ethers, Cyclic; Guinea Pigs; Male; Okadaic Acid; Pepsinogens; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Polyenes; Signal Transduction; Sirolimus; Stomach; Tacrolimus | 1996 |
Cycloheximide-induced activation of mouse eggs: effects on cdc2/cyclin B and MAP kinase activities.
Topics: Animals; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Chromatin; Cyclin B; Cyclin B1; Cyclins; Cycloheximide; DNA Replication; Egg Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Half-Life; Maturation-Promoting Factor; Membrane Glycoproteins; Mice; Nocodazole; Okadaic Acid; Oocytes; Phosphorylation; Receptors, Cell Surface; Zona Pellucida Glycoproteins | 1996 |
Post-translational regulation of neuronal acetylcholine receptors stably expressed in a mouse fibroblast cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cycloheximide; Ethers, Cyclic; Isoquinolines; Mice; Nicotine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Receptors, Cholinergic; Sulfonamides | 1996 |
Okadaic acid potentiates 3-methylcholanthrene-induced CYP2A8 gene expression in primary cultures of Syrian hamster hepatocytes: possible involvement of activator protein-1.
Topics: Animals; Anisomycin; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cell Nucleus; Cells, Cultured; Colforsin; Consensus Sequence; Cricetinae; Cycloheximide; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Genes, fos; Genes, jun; Kinetics; Liver; Mesocricetus; Methylcholanthrene; Mixed Function Oxygenases; Molecular Sequence Data; Okadaic Acid; Oligodeoxyribonucleotides; Phosphoprotein Phosphatases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Transcription Factor AP-1; Transcription, Genetic | 1996 |
Okadaic acid overrides the S-phase check point and accelerates progression of G2-phase to induce premature mitosis in HeLa cells.
Topics: Cell Cycle; Chromosomes, Human; Cyclin B; Cyclin B1; Cyclins; Cycloheximide; Ethers, Cyclic; G2 Phase; HeLa Cells; Humans; Mitosis; Okadaic Acid; Protein Synthesis Inhibitors; S Phase | 1996 |
Okadaic acid increases fibronectin synthesis in MC3T3-E1 cells.
Topics: Animals; Blotting, Northern; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibronectins; Gene Expression Regulation; Mice; Okadaic Acid; Osteoblasts; Phosphoric Monoester Hydrolases; Precipitin Tests; RNA, Messenger; Skull | 1996 |
The protein phosphatase inhibitor okadaic acid suppresses type I collagen gene expression in cultured fibroblasts at the transcriptional level.
Topics: 3T3 Cells; Animals; Blotting, Northern; Collagen; Cycloheximide; Dexamethasone; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Glycoproteins; Humans; Matrix Metalloproteinase 3; Mice; Okadaic Acid; Procollagen; Promoter Regions, Genetic; RNA, Messenger; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Up-Regulation | 1995 |
Resumption of meiosis is initiated by the accumulation of cyclin B in bovine oocytes.
Topics: Adenine; Animals; Cattle; Cell Nucleus; Cyclins; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Epidermal Growth Factor; Female; Humans; Meiosis; Microinjections; Okadaic Acid; Oocytes; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors | 1996 |
Interphase-like chromatin configuration induced by cycloheximide in maturing pig oocytes: effects of protein phosphatase inhibitors.
Topics: Animals; Chromatin; Cycloheximide; Enzyme Inhibitors; Female; Interphase; Kinetics; Marine Toxins; Microtubules; Okadaic Acid; Oocytes; Oxazoles; Phosphoprotein Phosphatases; Protein Synthesis Inhibitors; Swine; Tubulin | 1996 |
Ribosomal S6 kinase p90rsk and mRNA cap-binding protein eIF4E phosphorylations correlate with MAP kinase activation during meiotic reinitiation of mouse oocytes.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Female; Meiosis; Mice; Okadaic Acid; Oocytes; Peptide Initiation Factors; Phosphorylation; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Ribosomal Protein S6 Kinases; RNA Cap-Binding Proteins; RNA Caps; RNA-Binding Proteins; Signal Transduction | 1997 |
Sensitization to DNA damage by okadaic acid or bromodeoxyuridine involves unequal effects on melanoma cell adhesion and differentiation.
Topics: Animals; Antimetabolites, Antineoplastic; Arsenicals; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cycloheximide; DNA Damage; DNA Fragmentation; Enzyme Inhibitors; Melanoma; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Pigmentation; Protein Synthesis Inhibitors; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Ultraviolet Rays | 1997 |
Effect of a protein phosphatase inhibitor, okadaic acid, on thrombomodulin expression in cultured human umbilical vein endothelial cells.
Topics: Blotting, Northern; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Enzyme Inhibitors; Humans; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; Thrombomodulin; Umbilical Veins | 1997 |
Increase in AP-1 transcription factor DNA binding activity by valproic acid.
Topics: Activating Transcription Factor 2; Animals; Anticonvulsants; Brain; Cyclic AMP Response Element-Binding Protein; Cycloheximide; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Humans; Indoles; Maleimides; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Time Factors; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured; Valproic Acid | 1997 |
Zinc enhancement of 17beta-estradiol's anabolic effect in osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Carnosine; Cell Count; Cells, Cultured; Cycloheximide; DNA; Drug Synergism; Enzyme Inhibitors; Estradiol; Iron Chelating Agents; Mice; Okadaic Acid; Organometallic Compounds; Osteoblasts; Picolinic Acids; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proteins; Staurosporine; Zinc; Zinc Compounds; Zinc Sulfate | 1997 |
Epidermal growth factor and okadaic acid stimulate Sp1 proteolysis.
Topics: Amino Acid Sequence; Animals; Cell Division; Cycloheximide; Epidermal Growth Factor; Humans; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protease Inhibitors; Rats; Sp1 Transcription Factor; Transcriptional Activation; Tumor Cells, Cultured | 1997 |
Inhibitors of phosphoprotein phosphatases 1 and 2A cause activation of a 53 kDa protein kinase accompanying the apoptotic response of breast cancer cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Marine Toxins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 1; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1997 |
Regulation of ERK2 dephosphorylation in G1-stimulated rat T lymphoblasts.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Dactinomycin; Dual Specificity Phosphatase 2; Enzyme Activation; Enzyme Inhibitors; G1 Phase; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Rats; RNA, Messenger; T-Lymphocytes; Vanadates | 1997 |
Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.
Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Dual Specificity Phosphatase 1; Enzyme Activation; Glomerular Mesangium; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; NF-kappa B; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vanadates | 1998 |
Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation.
Topics: Animals; Cell Hypoxia; Cycloheximide; Enzyme Inhibitors; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Myocardium; Okadaic Acid; Oxygen; Protein Synthesis Inhibitors; Rats; RNA; RNA-Binding Proteins; Tumor Cells, Cultured | 1998 |
Inhibition of LPS-mediated activation in rat Kupffer cells by N-acetylcysteine occurs subsequent to NF-kappaB translocation and requires protein synthesis.
Topics: Acetylcysteine; Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kupffer Cells; Lipopolysaccharides; Macrophage Activation; Male; NF-kappa B; Okadaic Acid; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha | 1998 |
Prostaglandin endoperoxide H synthase-2 expression in human amnion cells: involvement of tyrosine kinases in the regulation.
Topics: Amnion; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Enzyme Induction; Epidermal Growth Factor; Female; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Membrane Proteins; Mitogen-Activated Protein Kinases; Okadaic Acid; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
SPIN, a substrate in the MAP kinase pathway in mouse oocytes.
Topics: Adenine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cycloheximide; Enzyme Inhibitors; Female; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mutagenesis; Okadaic Acid; Oocytes; Phosphoproteins; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-mos; Spindle Apparatus; Substrate Specificity | 1998 |
Reversible protein phosphorylation regulates jasmonic acid-dependent and -independent wound signal transduction pathways in Arabidopsis thaliana.
Topics: Arabidopsis; Cycloheximide; Cyclopentanes; Enzyme Inhibitors; Feedback; Gene Expression Regulation, Plant; Genes, Plant; Indoleacetic Acids; Models, Biological; Okadaic Acid; Oxylipins; Phosphoprotein Phosphatases; Phosphorylation; Plant Growth Regulators; Plant Proteins; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Transcriptional Activation | 1998 |
Okadaic acid-induced lens epithelial cell apoptosis requires inhibition of phosphatase-1 and is associated with induction of gene expression including p53 and bax.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cell Survival; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation; Genes, p53; Lens, Crystalline; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Protein Phosphatase 1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rabbits | 1998 |
Estrogenic and anti-estrogenic regulation of estrogen receptor in MCF-7 breast-cancer cells: comparison of immunocytochemical data with biochemical measurements.
Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Humans; Immunoenzyme Techniques; Immunohistochemistry; Kinetics; Okadaic Acid; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured | 1998 |
Okadaic acid-stimulated degradation of p35, an activator of CDK5, by proteasome in cultured neurons.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Enzyme Inhibitors; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Okadaic Acid; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rats | 1998 |
Apoptosis and mitotic arrest are two independent effects of the protein phosphatases inhibitor okadaic acid in K562 leukemia cells.
Topics: Apoptosis; Cell Cycle; Cyclin A; Cyclin B; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histones; Humans; Hydroxyurea; K562 Cells; Mitosis; Nocodazole; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2; Time Factors | 1999 |
Agonist-dependent up-regulation of human somatostatin receptor type 1 requires molecular signals in the cytoplasmic C-tail.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Cycloheximide; Endocytosis; Fluoroimmunoassay; Humans; Molecular Sequence Data; Mutation; Okadaic Acid; Receptors, Somatostatin; Recombinant Fusion Proteins; Transfection; Up-Regulation; Virulence Factors, Bordetella | 1999 |
The protein phosphatase inhibitors, okadaic acid and calyculin A, induce apoptosis in human submandibular gland ductal cell line HSG cells.
Topics: Apoptosis; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Humans; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Synthesis Inhibitors; Salivary Ducts; Submandibular Gland | 1999 |
Inhibitors of protein synthesis and RNA synthesis protect against okadaic acid-induced apoptosis in human osteosarcoma cell line MG63 cells but not in Saos-2 cells.
Topics: Apoptosis; Cell Nucleus; Cycloheximide; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Humans; Okadaic Acid; Osteosarcoma; Protein Synthesis Inhibitors; Puromycin; RNA; Tumor Cells, Cultured | 1999 |
Expression of leptin mRNA and CCAAT-enhancer binding proteins in response to insulin deprivation during preadipocyte differentiation in primary cultures of porcine stromal-vascular cells.
Topics: Adipocytes; Adipose Tissue; Animals; Cattle; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cells, Cultured; Cycloheximide; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Developmental; Insulin; Leptin; Nuclear Proteins; Okadaic Acid; Protein Synthesis Inhibitors; RNA, Messenger; Swine | 1999 |
Syringolin-mediated activation of the Pir7b esterase gene in rice cells is suppressed by phosphatase inhibitors.
Topics: Carbazoles; Cycloheximide; Enzyme Inhibitors; Esterases; Indole Alkaloids; Okadaic Acid; Oryza; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Staurosporine; Transcription, Genetic | 2000 |
Involvement of cumulus cells stimulated by FSH in chromatin condensation and the activation of maturation-promoting factor in bovine oocytes.
Topics: Animals; Cattle; CDC2 Protein Kinase; Cells, Cultured; Chromatin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Female; Follicle Stimulating Hormone; Homeostasis; Kinetics; Okadaic Acid; Oocytes; Oogenesis; Ovarian Follicle; Phosphorylation | 1998 |
Okadaic acid induces cycloheximide and caspase sensitive apoptosis in immature neurons.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carrier Proteins; Caspase Inhibitors; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Hippocampus; Microfilament Proteins; Neurons; Okadaic Acid; Phosphatidylserines; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Myosin heavy chain degradation during apoptosis in endothelial cells.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Aorta; Apoptosis; Blotting, Western; Cattle; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Electrophoresis, Gel, Two-Dimensional; Endothelium, Vascular; Enzyme Inhibitors; Microscopy, Electron; Molecular Sequence Data; Molecular Weight; Myosin Heavy Chains; Okadaic Acid; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha; Vimentin | 2000 |
Screening of wound-responsive genes identifies an immediate-early expressed gene encoding a highly charged protein in mechanically wounded tobacco plants.
Topics: Amino Acid Sequence; Cycloheximide; Cytosol; DNA, Complementary; Egtazic Acid; Erythrosine; Gene Expression Regulation, Plant; Genes, Immediate-Early; Immediate-Early Proteins; Kinetics; Molecular Sequence Data; Molecular Weight; Nicotiana; Okadaic Acid; Plant Proteins; Plants, Toxic; Propionates; Sequence Homology, Amino Acid; Staurosporine; Time Factors; Transcription, Genetic | 2000 |
Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid.
Topics: Cycloheximide; Cyclooxygenase 2; Dactinomycin; Depression, Chemical; Drug Tolerance; Enzyme Inhibitors; Gene Expression Regulation; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
De novo activation of the beta-phaseolin promoter by phosphatase or protein synthesis inhibitors.
Topics: Cycloheximide; DNA Replication; Enzyme Inhibitors; Fabaceae; Okadaic Acid; Phosphoprotein Phosphatases; Plant Proteins; Plants, Medicinal; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Transcriptional Activation | 2001 |
Induction of apoptosis in normal cultured rat hepatocytes and in Hep3B, a human hepatoma cell line.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Carcinoma, Hepatocellular; Cell Culture Techniques; Cycloheximide; Fluorescent Dyes; Hepatocytes; Humans; Indoles; Liver Neoplasms; Okadaic Acid; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tretinoin; Tumor Cells, Cultured | 2000 |
Multiple signaling pathways in gene expression during sugar starvation. Pharmacological analysis of din gene expression in suspension-cultured cells of Arabidopsis.
Topics: Arabidopsis; Blotting, Northern; Carbohydrates; Cells, Cultured; Cycloheximide; Cytochrome c Group; Darkness; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Plant; Light-Harvesting Protein Complexes; Marine Toxins; Okadaic Acid; Oxazoles; Oxidoreductases; Phosphoprotein Phosphatases; Phosphorylation; Photosynthetic Reaction Center Complex Proteins; Plant Proteins; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction | 2000 |
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
Topics: Aldehydes; Alzheimer Disease; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Lipid Peroxidation; Nerve Degeneration; Neurons; NF-kappa B; Okadaic Acid; Protein Synthesis Inhibitors; Rats; Stroke; Transcription Factor AP-1; Vanadates | 2000 |
Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells.
Topics: Acetylcysteine; Cell Line; Cycloheximide; Enzyme Inhibitors; Glutathione; Humans; Interleukin-1; Lipopolysaccharides; Macrophages; NF-kappa B; Okadaic Acid; Protein Isoforms; Protein Synthesis Inhibitors; RNA, Messenger | 2000 |
Cytoplasmic changes in relation to nuclear maturation and early embryo developmental potential of porcine oocytes: effects of gonadotropins, cumulus cells, follicular size, and protein synthesis inhibition.
Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Blastocyst; Cell Nucleus; Cells, Cultured; Cyclin B; Cyclin B1; Cycloheximide; Cytoplasm; Cytoplasmic Granules; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Immunoblotting; Luteinizing Hormone; Meiosis; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nocodazole; Okadaic Acid; Oocytes; Ovarian Follicle; Protein Synthesis Inhibitors; Swine | 2001 |
Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking.
Topics: Animals; beta-Cyclodextrins; Biological Transport; Caveolae; Caveolin 1; Caveolins; Cyclodextrins; Cycloheximide; Cytochalasin D; Dogs; Endocytosis; Epithelial Cells; Green Fluorescent Proteins; HeLa Cells; Humans; Kinetics; Luminescent Proteins; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 2002 |
Signal transduction controlling the blue- and red-light mediated gene expression of S-adenosylmethionine decarboxylase in Pharbitis nil.
Topics: Adenosylmethionine Decarboxylase; Calcium; Calcium Channel Blockers; Calmodulin; Carbazoles; Convolvulaceae; Cycloheximide; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indole Alkaloids; Light; Nifedipine; Okadaic Acid; Phytochrome; Signal Transduction; Trifluoperazine | 2002 |
Oxidized low density lipoprotein induces the cyclin-dependent kinase inhibitor p21(waf1) and the tumor suppressor Rb.
Topics: Antioxidants; Cell Line; Cell Nucleus; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; G1 Phase; Genes, p53; Humans; Immunoblotting; Lipid Peroxidation; Lipoproteins, LDL; Okadaic Acid; Oxidative Stress; Oxygen; Phosphorylation; Retinoblastoma Protein; Time Factors; Vitamin E | 2002 |
Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; GTP-Binding Proteins; Imidazoles; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Interleukin-1; Interleukin-13; Interleukin-4; NF-kappa B; Okadaic Acid; Osmosis; Phosphoproteins; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
The intracellular pH-regulatory HCO3-/Cl- exchanger in the mouse oocyte is inactivated during first meiotic metaphase and reactivated after egg activation via the MAP kinase pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bucladesine; Butadienes; Calcium; Chloride-Bicarbonate Antiporters; Cycloheximide; Demecolcine; Enzyme Inhibitors; Female; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Maturation-Promoting Factor; Meiosis; Mice; Nitriles; Okadaic Acid; Oocytes; Pregnancy; Strontium | 2002 |
Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Enzyme Inhibitors; Neurons; Okadaic Acid; Protein Synthesis Inhibitors; Rats; Time Factors | 2002 |
Stress-induced protein phosphatase 2C is a negative regulator of a mitogen-activated protein kinase.
Topics: Arabidopsis; Caseins; Cycloheximide; Edetic Acid; Enzyme Activation; Enzyme Inhibitors; Immunosorbent Techniques; Medicago sativa; Mitogen-Activated Protein Kinases; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plant Extracts; Plant Leaves; Plant Proteins; Protein Phosphatase 2C; Protein Synthesis Inhibitors; Recombinant Proteins; RNA, Messenger; Substrate Specificity; Threonine; Two-Hybrid System Techniques; Vanadates | 2003 |
Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development.
Topics: 2,4-Dichlorophenoxyacetic Acid; Arabidopsis; Arabidopsis Proteins; Blotting, Northern; Blotting, Southern; Blotting, Western; Brassinosteroids; Cholestanols; Cycloheximide; DNA-Binding Proteins; DNA, Antisense; Down-Regulation; Flowers; Gene Dosage; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Models, Biological; Mutation; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Plant Growth Regulators; Plant Leaves; Plant Roots; Plants, Genetically Modified; Protein Kinases; Rhizobium; Signal Transduction; Staurosporine; Steroids, Heterocyclic; Transformation, Genetic; Zeatin | 2004 |
Induction of SULTR1;1 sulfate transporter in Arabidopsis roots involves protein phosphorylation/dephosphorylation circuit for transcriptional regulation.
Topics: Anion Transport Proteins; Arabidopsis; Arabidopsis Proteins; Carrier Proteins; Cycloheximide; Dactinomycin; Gene Expression Regulation, Plant; Green Fluorescent Proteins; Luminescent Proteins; Marine Toxins; Membrane Transport Proteins; Okadaic Acid; Oxazoles; Phosphorylation; Plant Roots; Plants, Genetically Modified; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Sulfate Transporters; Sulfur | 2004 |
Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Chemotaxis; Cycloheximide; Enzyme Inhibitors; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Lipopolysaccharides; Lysine; Male; Monocytes; Neutrophils; Okadaic Acid; Pneumonia; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Effects of MAP kinase pathway and other factors on meiosis of Urechis unicinctus eggs.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Annelida; Calcimycin; Chromosomes; Colforsin; Cycloheximide; Diglycerides; Extracellular Signal-Regulated MAP Kinases; Fertilization; Flavonoids; MAP Kinase Signaling System; Meiosis; Okadaic Acid; Ovum; Parthenogenesis; Phosphorylation | 2005 |
Analysis of mitotic phosphorylation of borealin.
Topics: Amino Acid Substitution; Aurora Kinase B; Aurora Kinases; Benzamides; CDC2 Protein Kinase; Cell Cycle Proteins; Centromere; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Consensus Sequence; Cycloheximide; G2 Phase; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitor of Apoptosis Proteins; Interphase; Metaphase; Microtubule-Associated Proteins; Mitosis; Multiprotein Complexes; Mutagenesis, Site-Directed; Mutation, Missense; Neoplasm Proteins; Nocodazole; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperazines; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Quinazolines; Recombinant Fusion Proteins; Sodium Fluoride; Spindle Apparatus; Substrate Specificity; Survivin; Transfection | 2007 |
Coordinate regulation of phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase by light and CO2 during C4 photosynthesis.
Topics: Amino Acid Sequence; Carbon Dioxide; Cycloheximide; Dithiothreitol; Light; Molecular Sequence Data; Okadaic Acid; Panicum; Phosphoenolpyruvate Carboxykinase (ATP); Phosphoenolpyruvate Carboxylase; Phosphorylation; Photosynthesis; Sequence Alignment | 2007 |
Cell growth inhibition by okadaic acid involves gut-enriched Kruppel-like factor mediated enhanced expression of c-Myc.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Okadaic Acid; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Signal Transduction; Transcription, Genetic | 2007 |
Novel rice OsSIPK is a multiple stress responsive MAPK family member showing rhythmic expression at mRNA level.
Topics: Abscisic Acid; Blotting, Northern; Cantharidin; Cell Nucleus; Chitosan; Cycloheximide; Cyclopentanes; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Okadaic Acid; Organophosphorus Compounds; Oryza; Oxylipins; Plant Leaves; Plant Proteins; RNA, Messenger; Salicylic Acid; Seedlings; Sequence Analysis, DNA; Sulfur Dioxide; Ultraviolet Rays | 2008 |
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.
Topics: Alternative Splicing; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Emetine; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Marine Toxins; Okadaic Acid; Oxazoles; Prostatic Neoplasms; Protein Phosphatase 1; Protein Phosphatase 2; Up-Regulation; Uterine Cervical Neoplasms | 2007 |
Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.
Topics: Androstadienes; Animals; Antigens, Surface; Apoptosis; Cell Adhesion; Cells, Cultured; Cycloheximide; Endothelial Cells; Enzyme Inhibitors; Humans; Interleukin-1beta; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; NADH Dehydrogenase; Okadaic Acid; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha; von Willebrand Factor; Wortmannin | 2009 |
Phosphorylation of human enhancer of filamentation (HEF1) on serine 369 induces its proteasomal degradation.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Cell Line, Tumor; Cycloheximide; Enzyme Inhibitors; HCT116 Cells; HT29 Cells; Humans; Indoles; Keratinocytes; Mutation; Okadaic Acid; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein-Tyrosine Kinases; RNA, Messenger; RNA, Small Interfering; Serine; Sulfonamides; Time Factors; Transfection | 2009 |
Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin.
Topics: Acrylamides; Adenosine Triphosphatases; Animals; Carcinogens; Cnidarian Venoms; Cycloheximide; Enzyme Inhibitors; HeLa Cells; Humans; Keratinocytes; Mice; Mitogen-Activated Protein Kinase 7; Okadaic Acid; Ouabain; Protein Synthesis Inhibitors; Vanadates | 2009 |
Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Cell Line, Tumor; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Lewy Bodies; Neurons; Okadaic Acid; Parkinson Disease; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Phosphatase 1; Protein Phosphatase 2; Protein Synthesis Inhibitors; Rabbits; Ubiquitin | 2010 |
Carfilzomib induces leukaemia cell apoptosis via inhibiting ELK1/KIAA1524 (Elk-1/CIP2A) and activating PP2A not related to proteasome inhibition.
Topics: Adult; Aged; Animals; Apoptosis; Autoantigens; Cell Line, Tumor; Cycloheximide; Down-Regulation; Female; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; K562 Cells; Leukemia; Male; Membrane Proteins; Mice, Nude; Middle Aged; Neoplasm Transplantation; Okadaic Acid; Oligopeptides; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
Cellular recovery from exposure to sub-optimal concentrations of AB toxins that inhibit protein synthesis.
Topics: Animals; Apoptosis; Bacterial Toxins; Cell Survival; Chemical Warfare Agents; Chlorocebus aethiops; Cycloheximide; Dose-Response Relationship, Drug; Enterotoxins; Escherichia coli Proteins; Genes, Reporter; Green Fluorescent Proteins; Half-Life; Marine Toxins; Okadaic Acid; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Stability; Proteolysis; Ricin; Spectrometry, Fluorescence; Vero Cells | 2018 |
PP1/PP2A phosphatase inhibition-induced metaplasticity in protein synthesis blocker-treated hippocampal slices: LTP and LTD, or There and Back again.
Topics: Animals; Anisomycin; CA1 Region, Hippocampal; Cycloheximide; Electric Stimulation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Marine Toxins; Neuronal Plasticity; Nitric Oxide; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Protein Synthesis Inhibitors; Rats; Rats, Wistar | 2021 |