cycloheximide has been researched along with mevalonic acid in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (60.00) | 18.7374 |
| 1990's | 13 (28.89) | 18.2507 |
| 2000's | 4 (8.89) | 29.6817 |
| 2010's | 1 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McGrath, RM; Neethling, DC | 1 |
| Edwards, PA | 3 |
| Blankenhorn, DH; Kalra, VK | 1 |
| Aiyar, AS; Gopalaswamy, UV | 1 |
| Nilsson, A | 1 |
| Nebert, DW; Puga, A; Raychaudhuri, B | 1 |
| Hidaka, Y; Horie, M; Hotta, H; Iwasawa, Y; Kamei, T; Nagata, Y | 1 |
| Langan, TJ; Slater, MC | 2 |
| Bansal, N; Houle, A; Melnykovych, G | 1 |
| Bar-Nun, S; Chun, KT; Simoni, RD | 1 |
| Maltese, WA; Repko, EM | 1 |
| Bankhurst, AD; Cutts, JL; Scallen, TJ; Watson, J | 1 |
| Farnsworth, DE; Feyereisen, R | 2 |
| Chang, CC; Chang, TY | 1 |
| Maltese, WA; Sheridan, KM | 1 |
| Brown, MS; Dana, SE; Goldstein, JL | 1 |
| Kirsten, ES; Watson, JA | 1 |
| Jakoi, L; Quarfordt, SH | 1 |
| Dugan, RE; Lakshmanan, MR; Nepokroeff, CM; Ness, GC; Porter, JW | 1 |
| Berndt, J; Gaumert, R; Löwel, M | 1 |
| Edmond, J; Fogelman, AM; Polito, A; Popják, G | 1 |
| Rodwell, VW; Shapiro, DJ | 2 |
| Avigan, J; Bhathena, SJ; Schreiner, ME; Williams, CD | 1 |
| McNamara, DJ; Quackenbush, FW; Rodwell, VW | 2 |
| Back, P; Hamprecht, B; Lynen, F | 1 |
| Löser, R; Moreth, W; Schliack, M | 1 |
| Miller, LR; Raulston, DL; Schroepfer, GJ | 1 |
| Gayen, AK; Peffley, DM | 1 |
| Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D | 1 |
| Endo, A; Hasumi, K; Miura, S | 1 |
| Chambers, C; Keller, RK; Ness, GC; Zhao, Z | 1 |
| Bifulco, M; Bruni, CB; Bucci, C; Laezza, C; Santillo, M | 1 |
| Benford, HL; Coxon, FP; Rogers, MJ; Russell, RG | 1 |
| Choi, JW; Jung, SE | 1 |
| Hohl, RJ; Holstein, SA; Wohlford-Lenane, CL | 2 |
| Horiuchi, N; Maeda, T | 1 |
| Alonso, S; Alvarez, Y; Fernández, N; Municio, C; San Román, JA; Sánchez Crespo, M | 1 |
| Acquavella, N; Cardier, JE; Quiroga, MF; Wittig, O | 1 |
45 other study(ies) available for cycloheximide and mevalonic acid
| Article | Year |
|---|---|
Metabolic development and mitochondrial changes during cyclopiazonic acid production in Penicillium cyclopium.
Topics: Adenosine Triphosphate; Chemical Phenomena; Chemistry; Cyclic AMP; Cycloheximide; Fungal Proteins; Glucose; Hydrogen-Ion Concentration; Indoles; Iron; Mevalonic Acid; Mitochondria; Mycotoxins; Nitrates; Nitrogen; Oxygen; Penicillium; Phosphates; Tryptophan; Zinc | 1977 |
The influence of catecholamines and cyclic AMP on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and lipid biosynthesis in isolated rat hepatocytes.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Catecholamines; Cell Survival; Cholesterol; Cyclic AMP; Cycloheximide; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Lipids; Liver; Male; Mevalonic Acid; Microsomes, Liver; Monoamine Oxidase; Perfusion; Protein Biosynthesis; Rats; Sterols | 1975 |
Effect of plasma lipoproteins and lecithin-cholesterol dispersions on the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase of isolated rat hepatocytes.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Cholesterol; Cycloheximide; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Lipids; Lipoproteins; Liver; Mevalonic Acid; Phosphatidylcholines; Rats; Tyrosine Transaminase | 1975 |
Abnormal activation of sterol synthesis in lymphocytes of atherosclerotic-susceptible pigeons and heterozygous familial hypercholesterolemic patients.
Topics: Acetates; Adult; Animals; Arteriosclerosis; Cholesterol; Columbidae; Cycloheximide; Humans; Hypercholesterolemia; Lipid Metabolism; Lymphocytes; Mevalonic Acid; Sterols | 1976 |
Actinomycin D-induced enhancement of ubiquinone biosynthesis in rat.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Biological Transport, Active; Cholesterol; Cycloheximide; Dactinomycin; In Vitro Techniques; Kidney; Liver; Male; Mevalonic Acid; Puromycin; Rats; Ubiquinone | 1976 |
Increased cholesterol-ester formation during forced cholesterol synthesis in rat hepatocytes.
Topics: Animals; Carbon Radioisotopes; Cholesterol; Cycloheximide; Esters; In Vitro Techniques; Isotope Labeling; Kinetics; Liver; Male; Mevalonic Acid; Microscopy, Phase-Contrast; Oleic Acids; Rats; Tritium | 1975 |
Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin.
Topics: Animals; Cell Line; Cell Nucleus; Cycloheximide; Cytochrome P-450 Enzyme System; DNA Probes; Enzyme Activation; Enzyme Repression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Mice; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger; Transcription, Genetic; Transfection | 1992 |
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes | 1991 |
Isoprenoids and astroglial cell cycling: diminished mevalonate availability and inhibition of dolichol-linked glycoprotein synthesis arrest cycling through distinct mechanisms.
Topics: Animals; Astrocytes; Cells, Cultured; Cycloheximide; Dolichols; G1 Phase; Glycoproteins; Interphase; Kinetics; Lovastatin; Mevalonic Acid; Rats; S Phase; Tunicamycin | 1991 |
Cell cycling of astrocytes and their precursors in primary cultures: a mevalonate requirement identified in late G1, but before the G1/S transition, involves polypeptides.
Topics: Animals; Astrocytes; Blood; Cell Cycle; Cells, Cultured; Cycloheximide; DNA; Interphase; Mevalonic Acid; Nerve Tissue Proteins; Peptides; S Phase; Stem Cells; Time Factors | 1991 |
Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents.
Topics: Cell Division; Cell Survival; Cycloheximide; Dactinomycin; Deoxyribonucleases; Dexamethasone; DNA Damage; Humans; Hydroxycholesterols; In Vitro Techniques; Leukemia, T-Cell; Lovastatin; Mevalonic Acid; Mifepristone; Nuclear Proteins; Tumor Cells, Cultured | 1991 |
The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum.
Topics: Animals; Brefeldin A; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum; Female; Hydroxymethylglutaryl CoA Reductases; Intracellular Membranes; Lovastatin; Mevalonic Acid; Ovary; Proteins; Recombinant Fusion Proteins; Transfection | 1990 |
Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability.
Topics: Animals; Cell Line; Cholesterol; Cycloheximide; Dolichols; Kinetics; Leucine; Lovastatin; Mevalonic Acid; Protein Processing, Post-Translational; Tritium; Ubiquinone | 1989 |
Role of mevalonic acid in the regulation of natural killer cell cytotoxicity.
Topics: Cell Line; Cell Survival; Cells, Cultured; Cholesterol; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Dolichols; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lovastatin; Mevalonic Acid; Sterols | 1989 |
Characterization and regulation of HMG-CoA reductase during a cycle of juvenile hormone synthesis.
Topics: Animals; Cockroaches; Corpora Allata; Cycloheximide; Enzyme Activation; Farnesol; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Lovastatin; Mevalonic Acid; Microsomes; Sesquiterpenes; Stereoisomerism | 1987 |
Cycloheximide sensitivity in regulation of acyl coenzyme A:cholesterol acyltransferase activity in Chinese hamster ovary cells. 2. Effect of sterol endogenously synthesized.
Topics: Animals; Cell Line; Cholesterol; Cricetinae; Cricetulus; Culture Media; Cycloheximide; Enzyme Activation; Female; Kinetics; Lipoproteins, LDL; Mevalonic Acid; Ovary; Sterol O-Acyltransferase; Sterols | 1986 |
Precursor supply for insect juvenile hormone III biosynthesis in a cockroach.
Topics: Acetyl Coenzyme A; Animals; Cockroaches; Cycloheximide; Glucose; Leucine; Mathematics; Mevalonic Acid; Sesquiterpenes; Trehalose | 1987 |
Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis.
Topics: Acetates; Acetylcholinesterase; Animals; Axons; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cholesterol; Cycloheximide; Glycoproteins; Growth Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Naphthalenes; Neuroblastoma; Terpenes | 1985 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.
Topics: Abetalipoproteinemia; Alcohol Oxidoreductases; Carbon Radioisotopes; Cells, Cultured; Child; Cholesterol; Chromatography, Thin Layer; Cycloheximide; Fibroblasts; Glutarates; Homozygote; Humans; Hyperlipidemias; Infant, Newborn; Insulin; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Mevalonic Acid; Skin; Tritium | 1974 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.
Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation | 1974 |
The induction of hepatic cholesterol synthesis in the rat by lecithin mesophase infusions.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Coenzyme A; Cycloheximide; Dactinomycin; Eggs; Injections, Intravenous; Liver; Male; Mevalonic Acid; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Rats; Surface Properties | 1974 |
Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine.
Topics: Alcohol Oxidoreductases; Animals; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Glutarates; Hydrocortisone; Hypophysectomy; In Vitro Techniques; Kinetics; Mevalonic Acid; Microsomes, Liver; Rats; Stimulation, Chemical; Triiodothyronine | 1973 |
[Influence of protein biosynthesis inhibitors on the circadian rhythm of hydroxymethylglutaryl-CoA-reductase in the mouse liver].
Topics: Alcohol Oxidoreductases; Animals; Cholesterol; Circadian Rhythm; Coenzyme A; Cycloheximide; Dactinomycin; Fasting; Glutarates; Liver; Mevalonic Acid; Mice; Puromycin | 1972 |
Effect of adrenalectomy and hypophysectomy on the circadian rhythm of -hydroxy- -methylglutaryl coenzyme A reductase activity in rat liver.
Topics: Adrenal Glands; Adrenalectomy; Alcohol Oxidoreductases; Animals; Carbon Isotopes; Cholesterol; Circadian Rhythm; Cycloheximide; Epinephrine; Feeding Behavior; Glutarates; Hormones; Hypophysectomy; Injections; Kinetics; Lighting; Liver; Male; Mevalonic Acid; Microsomes, Liver; Pituitary Gland; Rats; Time Factors | 1973 |
Control of lipid metabolism in human leukocytes.
Topics: Acetates; Adult; Carbon Radioisotopes; Cholesterol; Cycloheximide; Digitonin; Fasting; Humans; Hypercholesterolemia; In Vitro Techniques; Leukocytes; Lipids; Mevalonic Acid; Middle Aged; Sterols; Triglycerides | 1973 |
Fine structure of the cyclic rhythm of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Differential effects of cholesterol feeding and fasting.
Topics: Alcohol Oxidoreductases; Animals; Carbon Isotopes; Cholesterol; Circadian Rhythm; Coenzyme A; Cycloheximide; Dietary Fats; Fasting; Female; Glutarates; Mevalonic Acid; Microsomes, Liver; Rats | 1972 |
In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells.
Topics: Acetates; Alanine; Animals; Aorta, Thoracic; Blood; Carbon Isotopes; Cells, Cultured; Cholesterol; Cycloheximide; DNA; Fatty Acids; Lipids; Mevalonic Acid; Protein Biosynthesis; Rabbits; Squalene; Sterols; Thymidine; Time Factors; Tritium | 1972 |
Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. Developmental pattern.
Topics: Alcohol Oxidoreductases; Animals; Animals, Newborn; Bile Ducts; Carbon Isotopes; Cholesterol; Circadian Rhythm; Cycloheximide; Embryonic and Fetal Development; Female; Gestational Age; Glutarates; Growth Hormone; Hydrocortisone; Liver; Male; Mevalonic Acid; Microsomes, Liver; Milk; Pregnancy; Rats; Thyroxine; Weaning | 1972 |
Cycloheximide and chloramphenicol: effect on rat liver acetate metabolism.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Isotopes; Chloramphenicol; Cholesterol; Cycloheximide; Depression, Chemical; Fatty Acids; Female; Liver; Mevalonic Acid; Rats; Time Factors | 1970 |
Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Carbon Isotopes; Cholesterol; Circadian Rhythm; Coenzyme A; Cycloheximide; Dietary Fats; Feedback; Female; Glutarates; In Vitro Techniques; Kinetics; Lipoproteins; Liver; Mevalonic Acid; Microsomes, Liver; Rats; Time Factors | 1971 |
Regulation of cholesterol biosynthesis in rat liver: diurnal changes of activity and influence of bile acids.
Topics: Acetates; Animals; Bile Acids and Salts; Carbon Isotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Circadian Rhythm; Cycloheximide; Diet; Ion Exchange Resins; Liver; Male; Mevalonic Acid; Rats; Statistics as Topic | 1969 |
Mode of action of terbufibrol (INN) a hypolipidemic agent on rat liver sterol synthesis.
Topics: Animals; Anticholesteremic Agents; Benzoates; Cholesterol; Circadian Rhythm; Cycloheximide; Dactinomycin; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Mevalonic Acid; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Sterols; Triglycerides | 1982 |
Cycloheximide inhibits sterol biosynthesis in cell-free preparations of rat liver.
Topics: Acetates; Animals; Cycloheximide; Cytosol; Liver; Male; Mevalonic Acid; Rats; Sterols | 1980 |
Mevalonate regulates polysome distribution and blocks translation-dependent suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA: relationship to translational control.
Topics: Actins; Animals; Cell Line; Cricetinae; Cycloheximide; Drug Synergism; Gene Expression Regulation; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mesocricetus; Mevalonic Acid; Polyribosomes; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic | 1995 |
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Inhibition of protein prenylation by patulin.
Topics: Alkyl and Aryl Transferases; Animals; Brain; Cells, Cultured; Cycloheximide; Leucine; Mevalonic Acid; Mice; Patulin; Protein Prenylation; Rats; Transferases; Trichothecenes | 1993 |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.
Topics: Animals; Anticholesteremic Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cycloheximide; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Half-Life; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver; Lovastatin; Male; Mevalonic Acid; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Time Factors; Tricarboxylic Acids | 1996 |
Control of Rab5 and Rab7 expression by the isoprenoid pathway.
Topics: Animals; Cell Line; Cycloheximide; Gene Expression Regulation; GTP Phosphohydrolases; GTP-Binding Proteins; Kinetics; Lovastatin; Mevalonic Acid; Protein Prenylation; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; rab7 GTP-Binding Proteins; Rats; RNA, Messenger; Thyroid Gland; Time Factors; Transcription, Genetic | 1998 |
Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs.
Topics: Alendronate; Animals; Apoptosis; Carbon Radioisotopes; Caspase 3; Caspases; Cell Line; Cycloheximide; Diphosphonates; Enzyme Activation; Enzyme Inhibitors; Lovastatin; Macrophages; Mevalonic Acid; Mice; Protein Biosynthesis; Protein Synthesis Inhibitors | 1998 |
Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells.
Topics: Anticholesteremic Agents; Apoptosis; Cell Division; Cell Line; Chromatin; Cycloheximide; Dactinomycin; DNA Fragmentation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Microscopy, Electron; Microscopy, Fluorescence; Neuroglia; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line; Cycloheximide; Dactinomycin; Humans; K562 Cells; Lovastatin; Mevalonic Acid; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Isoprenoids influence expression of Ras and Ras-related proteins.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cycloheximide; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; K562 Cells; Leucine; Lovastatin; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin | 2009 |
Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin.
Topics: Antigens, CD; Arachidonic Acid; Atorvastatin; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dendritic Cells; Dinoprostone; Gene Expression; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mevalonic Acid; Peptidoglycan; Phospholipases A2, Cytosolic; Pyrroles; Zymosan | 2009 |
Effect of simvastatin on endothelial cell apoptosis mediated by Fas and TNF-alpha.
Topics: Animals; Antibodies, Antinuclear; Anticholesteremic Agents; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Fas Ligand Protein; fas Receptor; Humans; Liver; Mevalonic Acid; Mice; Polyisoprenyl Phosphates; Protein Synthesis Inhibitors; Simvastatin; Tumor Necrosis Factor-alpha | 2010 |