cycloheximide has been researched along with lovastatin in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 17 (47.22) | 18.2507 |
| 2000's | 10 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nebert, DW; Puga, A; Raychaudhuri, B | 1 |
| Hidaka, Y; Horie, M; Hotta, H; Iwasawa, Y; Kamei, T; Nagata, Y | 1 |
| Langan, TJ; Slater, MC | 1 |
| Bansal, N; Houle, A; Melnykovych, G | 1 |
| Bar-Nun, S; Chun, KT; Simoni, RD | 1 |
| Maltese, WA; Repko, EM | 1 |
| Bankhurst, AD; Cutts, JL; Scallen, TJ; Watson, J | 1 |
| Iwaki, T; Noguchi, A; Sekimoto, T | 1 |
| Ness, GC; Simonet, WS | 1 |
| Farnsworth, DE; Feyereisen, R | 1 |
| Maltese, WA; Sheridan, KM | 1 |
| Logel, J; Schnitzer-Polokoff, R; Sinensky, M; Torget, R | 1 |
| Bhat, NR; Volpe, JJ | 1 |
| Cornell, RB; Horwitz, AF; Nissley, SM | 1 |
| Gayen, AK; Peffley, DM | 1 |
| Choi, JW; Peffley, DM | 1 |
| Borner, MM; Myers, CE; Sartor, O; Schneider, E; Sei, Y; Toko, T; Trepel, JB | 1 |
| Bertolotti, R; Bocharov, AV; Frolova, EG; Huang, W; Rampal, P; Vishniakova, TG; Zaitseva, EV | 1 |
| Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D | 1 |
| Choi, JW; Lundquist, EN; Peffley, DM | 1 |
| Chambers, C; Keller, RK; Ness, GC; Zhao, Z | 1 |
| Bhullar, RP | 1 |
| Aktories, K; Benz, C; Koch, G; Olenik, C; Schmidt, G | 1 |
| Bifulco, M; Bruni, CB; Bucci, C; Laezza, C; Santillo, M | 1 |
| Benford, HL; Coxon, FP; Rogers, MJ; Russell, RG | 1 |
| Choi, JW; Jung, SE | 1 |
| Aklilu, F; Gladu, J; Goltzman, D; Rabbani, SA | 1 |
| Avner, R; Doolman, R; Harats, D; Ravid, T; Roitelman, J | 1 |
| Hohl, RJ; Holstein, SA; Wohlford-Lenane, CL | 2 |
| Agarwal, B; Chen, M; Feoktistov, AS; Halmos, B; Holt, PR; Lamont, JT; Pothoulakis, C; Protiva, P; Ramey, WG | 1 |
| Hatakeyama, D; Hirade, K; Ito, H; Kato, K; Kozawa, O; Niwa, M; Tokuda, H; Wang, X | 1 |
| Dimitroulakos, J; Goss, G; Lorimer, IA; Mantha, AJ; McFee, KE; Niknejad, N | 1 |
| Hohl, RJ; Ownby, SE | 1 |
| Kong, JY; Lodha, P; Rabkin, SW | 1 |
| Bu, P; Perlman, JI; Richards, MP; Stubbs, EB; Von Zee, CL | 1 |
36 other study(ies) available for cycloheximide and lovastatin
| Article | Year |
|---|---|
Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin.
Topics: Animals; Cell Line; Cell Nucleus; Cycloheximide; Cytochrome P-450 Enzyme System; DNA Probes; Enzyme Activation; Enzyme Repression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Mice; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger; Transcription, Genetic; Transfection | 1992 |
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes | 1991 |
Isoprenoids and astroglial cell cycling: diminished mevalonate availability and inhibition of dolichol-linked glycoprotein synthesis arrest cycling through distinct mechanisms.
Topics: Animals; Astrocytes; Cells, Cultured; Cycloheximide; Dolichols; G1 Phase; Glycoproteins; Interphase; Kinetics; Lovastatin; Mevalonic Acid; Rats; S Phase; Tunicamycin | 1991 |
Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents.
Topics: Cell Division; Cell Survival; Cycloheximide; Dactinomycin; Deoxyribonucleases; Dexamethasone; DNA Damage; Humans; Hydroxycholesterols; In Vitro Techniques; Leukemia, T-Cell; Lovastatin; Mevalonic Acid; Mifepristone; Nuclear Proteins; Tumor Cells, Cultured | 1991 |
The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum.
Topics: Animals; Brefeldin A; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum; Female; Hydroxymethylglutaryl CoA Reductases; Intracellular Membranes; Lovastatin; Mevalonic Acid; Ovary; Proteins; Recombinant Fusion Proteins; Transfection | 1990 |
Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability.
Topics: Animals; Cell Line; Cholesterol; Cycloheximide; Dolichols; Kinetics; Leucine; Lovastatin; Mevalonic Acid; Protein Processing, Post-Translational; Tritium; Ubiquinone | 1989 |
Role of mevalonic acid in the regulation of natural killer cell cytotoxicity.
Topics: Cell Line; Cell Survival; Cells, Cultured; Cholesterol; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Dolichols; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lovastatin; Mevalonic Acid; Sterols | 1989 |
Sources of extramitochondrial corticoidogenic cholesterol in the adrenal cortex.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Calcium; Cattle; Chloroquine; Cholesterol; Cricetinae; Cycloheximide; Dichlorvos; Female; In Vitro Techniques; Lovastatin; Male; Mesocricetus; Naphthalenes; Rats; Rats, Inbred Strains; Species Specificity; Sulfonamides | 1985 |
Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormones.
Topics: Actins; Animals; Colestipol; Cycloheximide; Diet; Gene Expression Regulation; Half-Life; Hydroxymethylglutaryl CoA Reductases; Hypophysectomy; Kinetics; Liver; Lovastatin; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Thyroid Hormones; Transcription, Genetic | 1988 |
Characterization and regulation of HMG-CoA reductase during a cycle of juvenile hormone synthesis.
Topics: Animals; Cockroaches; Corpora Allata; Cycloheximide; Enzyme Activation; Farnesol; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Lovastatin; Mevalonic Acid; Microsomes; Sesquiterpenes; Stereoisomerism | 1987 |
Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis.
Topics: Acetates; Acetylcholinesterase; Animals; Axons; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cholesterol; Cycloheximide; Glycoproteins; Growth Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Naphthalenes; Neuroblastoma; Terpenes | 1985 |
Analysis of the coordinate expression of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities in Chinese hamster ovary fibroblasts.
Topics: Animals; Cell Line; Cholesterol; Cricetinae; Cricetulus; Cycloheximide; Female; Fibroblasts; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Lovastatin; Mutation; Naphthalenes; Ovary; Oxo-Acid-Lyases | 1983 |
Relation of cholesterol to astrocytic differentiation in C-6 glial cells.
Topics: Animals; Anticholesteremic Agents; Astrocytes; Cell Differentiation; Cell Line; Cholesterol; Cycloheximide; Glioma; Glutamate-Ammonia Ligase; Kinetics; Lovastatin; Naphthalenes; Rats | 1984 |
Cholesterol availability modulates myoblast fusion.
Topics: Animals; Calcium; Cell Aggregation; Cell Fusion; Chickens; Cycloheximide; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Muscles; Naphthalenes; Tunicamycin | 1980 |
Mevalonate regulates polysome distribution and blocks translation-dependent suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA: relationship to translational control.
Topics: Actins; Animals; Cell Line; Cricetinae; Cycloheximide; Drug Synergism; Gene Expression Regulation; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mesocricetus; Mevalonic Acid; Polyribosomes; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic | 1995 |
3'-untranslated sequences mediate post-transcriptional regulation of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA by 25-hydroxycholesterol.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Culture Media; Cycloheximide; Depression, Chemical; Enzyme Induction; Genes, Reporter; Globins; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger | 1995 |
Drug-induced apoptosis is not necessarily dependent on macromolecular synthesis or proliferation in the p53-negative human prostate cancer cell line PC-3.
Topics: Antineoplastic Agents; Aphidicolin; Apoptosis; Cell Cycle; Cell Division; Cycloheximide; DNA, Neoplasm; Humans; Lovastatin; Male; Microscopy, Electron; Nucleosomes; Prostatic Neoplasms; Tumor Cells, Cultured | 1995 |
Glucocorticoids upregulate high-affinity, high-density lipoprotein binding sites in rat hepatocytes.
Topics: Adrenalectomy; Animals; Binding Sites; Cells, Cultured; Cholesterol; Cycloheximide; Dexamethasone; Humans; Lipoproteins, HDL; Liver; Lovastatin; Male; Rats; Rats, Wistar | 1995 |
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Inhibition of protein synthesis in baby-hamster kidney cells blocks oxysterol-mediated suppression of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA at a post-transcriptional level.
Topics: Animals; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; Gene Expression Regulation, Enzymologic; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Kidney; Lovastatin; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic | 1993 |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.
Topics: Animals; Anticholesteremic Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cycloheximide; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Half-Life; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver; Lovastatin; Male; Mevalonic Acid; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Time Factors; Tricarboxylic Acids | 1996 |
Expression of a 24 kDa GTP-binding protein (Gn24) is increased in lovastatin treated human erythroleukemia cells.
Topics: ADP Ribose Transferases; Anticholesteremic Agents; Bacterial Proteins; Botulinum Toxins; Cycloheximide; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; GTP-Binding Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Erythroblastic, Acute; Lovastatin; Molecular Weight; Neoplasm Proteins; Protein Prenylation; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 1996 |
Role of Rho protein in lovastatin-induced breakdown of actin cytoskeleton.
Topics: 3T3 Cells; Actins; Animals; Bacterial Toxins; Cycloheximide; Cytoskeleton; Cytotoxins; Escherichia coli Proteins; GTP-Binding Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Proteins; Mice; Rabbits; rhoB GTP-Binding Protein | 1997 |
Control of Rab5 and Rab7 expression by the isoprenoid pathway.
Topics: Animals; Cell Line; Cycloheximide; Gene Expression Regulation; GTP Phosphohydrolases; GTP-Binding Proteins; Kinetics; Lovastatin; Mevalonic Acid; Protein Prenylation; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; rab7 GTP-Binding Proteins; Rats; RNA, Messenger; Thyroid Gland; Time Factors; Transcription, Genetic | 1998 |
Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs.
Topics: Alendronate; Animals; Apoptosis; Carbon Radioisotopes; Caspase 3; Caspases; Cell Line; Cycloheximide; Diphosphonates; Enzyme Activation; Enzyme Inhibitors; Lovastatin; Macrophages; Mevalonic Acid; Mice; Protein Biosynthesis; Protein Synthesis Inhibitors | 1998 |
Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells.
Topics: Anticholesteremic Agents; Apoptosis; Cell Division; Cell Line; Chromatin; Cycloheximide; Dactinomycin; DNA Fragmentation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Microscopy, Electron; Microscopy, Fluorescence; Neuroglia; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide.
Topics: Animals; Antineoplastic Agents; Calcium; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Lovastatin; Male; Methionine; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Neoplasms, Experimental; Parathyroid Hormone-Related Protein; Proteins; Proto-Oncogene Proteins c-raf; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Signal Transduction; Ultraviolet Rays | 2000 |
The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Animals; beta-Galactosidase; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cholesterol; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Leupeptins; Lovastatin; Oligopeptides; Peptide Hydrolases; Precipitin Tests; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Tricarboxylic Acids; Ubiquitins | 2000 |
Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line; Cycloheximide; Dactinomycin; Humans; K562 Cells; Lovastatin; Mevalonic Acid; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.
Topics: Animals; Apoptosis; Bacterial Proteins; Bacterial Toxins; Blotting, Western; Cell Line; Cell Membrane; Cell Size; Cycloheximide; Cytoskeleton; Cytosol; Epithelial Cells; Flow Cytometry; In Situ Nick-End Labeling; Intestines; Lovastatin; Polyisoprenyl Phosphates; Protein Transport; Rats; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Time Factors | 2002 |
Isoprenoids influence expression of Ras and Ras-related proteins.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cycloheximide; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; K562 Cells; Leucine; Lovastatin; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Mechanism of simvastatin on induction of heat shock protein in osteoblasts.
Topics: 3T3 Cells; Animals; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Lovastatin; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Osteogenesis; p38 Mitogen-Activated Protein Kinases; Pyridines; Reproducibility of Results; RNA, Messenger; Sensitivity and Specificity; Simvastatin | 2003 |
Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Dactinomycin; Drug Delivery Systems; ErbB Receptors; Head and Neck Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Protein-Tyrosine Kinases | 2003 |
Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis.
Topics: Alcohols; Animals; Cycloheximide; Diterpenes; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lovastatin; Mice; Monomeric GTP-Binding Proteins; NIH 3T3 Cells; Protein Biosynthesis; Protein Prenylation; Protein Synthesis Inhibitors; ras Proteins; Terpenes | 2003 |
Reduction of protein synthesis and statin-induced cardiomyocyte cell death.
Topics: Animals; Autoradiography; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Chick Embryo; Coloring Agents; Cycloheximide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Myocytes, Cardiac; Protein Synthesis Inhibitors | 2007 |
Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin.
Topics: Actins; Cell Line, Transformed; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Lovastatin; Polyisoprenyl Phosphates; Prenylation; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA, Messenger; Subcellular Fractions; Trabecular Meshwork | 2009 |