Page last updated: 2024-08-17

cycloheximide and leptin

cycloheximide has been researched along with leptin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's20 (76.92)29.6817
2010's3 (11.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brichard, SM; Henquin, JC; Ongemba, LN; Pottier, AM; Reul, BA1
Bradley, RL; Cheatham, B1
Chen, XL; Dean, RG; Hausman, GJ1
Chickering, TW; Dussault, B; Friedman, JM; Holmes, WE; Qin, Y; Rosen, ED; Soukas, A; Spiegelman, BM; Yoon, JC1
Brolin, RE; Fried, SK; Magill, E; Ricci, MR; Russell, CD1
Berger, J; Elbrecht, A; Hermanowski-Vosatka, A; Moller, DE; Tanen, M; Thieringer, R; Wright, SD1
Levy, JR; Stevens, W1
André, J; Ferré, P; Guerre-Millo, M; Hainault, I; Quignard-Boulangé, A; Turban, S1
Finck, BN; Johnson, RW1
Anania, FA; Floyd, JJ; Saliba, G; Saxena, NK1
Gregoire, FM; Havel, PJ; Moreno-Aliaga, MJ; Stanhope, KL; Warden, CH1
Anania, FA; Ding, X; Floyd, J; Saxena, NK; Sitaraman, SV; Srinivasan, S; Titus, MA1
Lagace, DC; McLeod, RS; Nachtigal, MW1
Brolin, RE; Fried, SK; Lee, MJ; Ricci, MR; Russell, CD; Schneider, SH; Sullivan, S; Wang, Y1
Boyle, D; Mora, S; Pessin, JE; Sanford, D; Scherer, PE; Xie, L1
Calandra, RS; Gaillard, RC; Giovambattista, A; Piermaría, J; Spinedi, E; Suescun, MO1
Bendayan, M; Bukowiecki, LJ; Cammisotto, PG; Deshaies, Y1
Fried, SK; Lee, MJ1
Flier, JS; Gardner, NP; Guan, HP; Kershaw, EE; Lazar, MA; Schupp, M1
Chang, HH; Chien, YS; Ding, WH; Kao, YH; Ku, HC; Lee, MJ; Liao, WJ; Lin, H; Liu, CW; Wu, MH1
Friedman, JM; McGraw, TE; Rodeheffer, MS; Zeigerer, A1
Evans, JJ; Mason, DR; Peters, EE; Towler, KL1
Horiuchi, N; Maeda, T1
Brown, RE; Imran, SA; Wilkinson, DA; Wilkinson, M; Wilkinson, PM1
Biz Rodrigues Silva, C; Conde, SJ; de Oliveira, M; De Sibio, MT; Luvizotto, Rde A; Moretto, FC; Nogueira, CR; Olimpio, RM1
Cheong, JH; Chung, WT; Jeong, NY; Kim, HY; Kim, JH; Lee, SW; Lee, SY; Rho, JH; Yoo, YH1

Other Studies

26 other study(ies) available for cycloheximide and leptin

ArticleYear
Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue.
    The Biochemical journal, 1997, Jun-01, Volume: 324 ( Pt 2)

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cyclic AMP; Cycloheximide; Dexamethasone; Energy Metabolism; Enzyme Induction; Epididymis; Fatty Acid Synthases; Fatty Acids; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Leptin; Male; Microbodies; Monosaccharide Transport Proteins; Muscle Proteins; Organ Culture Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

1997
Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytes.
    Diabetes, 1999, Volume: 48, Issue:2

    Topics: Adipocytes; Animals; Cycloheximide; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Insulin; Leptin; Male; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Transcription, Genetic

1999
Expression of leptin mRNA and CCAAT-enhancer binding proteins in response to insulin deprivation during preadipocyte differentiation in primary cultures of porcine stromal-vascular cells.
    Domestic animal endocrinology, 1999, Volume: 17, Issue:4

    Topics: Adipocytes; Adipose Tissue; Animals; Cattle; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cells, Cultured; Cycloheximide; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Developmental; Insulin; Leptin; Nuclear Proteins; Okadaic Acid; Protein Synthesis Inhibitors; RNA, Messenger; Swine

1999
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation.
    Molecular and cellular biology, 2000, Volume: 20, Issue:14

    Topics: 3T3 Cells; Adipose Tissue; Amino Acid Sequence; Angiopoietin-Like Protein 2; Angiopoietin-Like Protein 4; Angiopoietin-like Proteins; Angiopoietins; Animals; Base Sequence; Blood Proteins; Cell Differentiation; Cycloheximide; Female; Gene Expression Regulation; Glycoproteins; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Leptin; Mice; Mice, Inbred C57BL; Mice, Obese; Molecular Sequence Data; Muscle Proteins; Nutritional Physiological Phenomena; Pioglitazone; Placenta; Pregnancy; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Thiazoles; Thiazolidinediones; Transcription Factors

2000
Regulation of the leptin content of obese human adipose tissue.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:3

    Topics: Adipose Tissue; Adult; Culture Techniques; Cycloheximide; Detergents; Dexamethasone; Drug Synergism; Female; Glucocorticoids; Humans; Insulin; Leptin; Male; Obesity; Octoxynol; Omentum; Protein Synthesis Inhibitors

2001
Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3 Cells; Adipocytes; Animals; Cycloheximide; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Hydroxysteroid Dehydrogenases; Kinetics; Leptin; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic

2001
The effects of insulin, glucose, and pyruvate on the kinetics of leptin secretion.
    Endocrinology, 2001, Volume: 142, Issue:8

    Topics: Adipocytes; Animals; Cycloheximide; Glucose; Insulin; Intracellular Membranes; Kinetics; Leptin; Male; Monensin; Protein Synthesis Inhibitors; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2001
Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen.
    Journal of cellular biochemistry, 2001, Volume: 82, Issue:4

    Topics: Adipocytes; Angiotensinogen; Animals; Brefeldin A; Cells, Cultured; Cycloheximide; Golgi Apparatus; Insulin; Kinetics; Leptin; Monensin; Protein Synthesis Inhibitors; Rats; Rats, Zucker

2001
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:5

    Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Homeostasis; Imidazoles; Immunologic Factors; Leptin; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha

2002
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells.
    Journal of cellular biochemistry, 2003, May-15, Volume: 89, Issue:2

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Collagen Type I; Cycloheximide; Dactinomycin; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Leptin; Liver; Male; Mice; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Transforming Growth Factor beta

2003
Effects of inhibiting transcription and protein synthesis on basal and insulin-stimulated leptin gene expression and leptin secretion in cultured rat adipocytes.
    Biochemical and biophysical research communications, 2003, Aug-08, Volume: 307, Issue:4

    Topics: Adipocytes; Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Dichlororibofuranosylbenzimidazole; Gene Expression Regulation; Glucose; Insulin; Insulin Antagonists; Leptin; Male; Nucleic Acid Synthesis Inhibitors; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Transcription, Genetic

2003
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:13

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspases; Cell Proliferation; Cells, Cultured; Chromones; Cyclin D1; Cycloheximide; DNA; DNA Replication; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Liver; Membrane Glycoproteins; Mitogens; Mitosis; Morpholines; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, Leptin; Repressor Proteins; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Necrosis Factor-alpha

2004
Valproic acid inhibits leptin secretion and reduces leptin messenger ribonucleic acid levels in adipocytes.
    Endocrinology, 2004, Volume: 145, Issue:12

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anticonvulsants; Carbon Radioisotopes; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Proteins; Cycloheximide; DNA-Binding Proteins; Energy Metabolism; Gene Expression; Glucose; Leptin; Lipid Metabolism; Mice; PPAR gamma; Protein Synthesis Inhibitors; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Valproic Acid

2004
Isoproterenol decreases leptin release from rat and human adipose tissue through posttranscriptional mechanisms.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:4

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Blotting, Northern; Cycloheximide; Isoproterenol; Kinetics; Leptin; Male; Obesity; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger

2005
Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: 3T3-L1 Cells; Adaptor Proteins, Vesicular Transport; Adipocytes; Adiponectin; ADP-Ribosylation Factors; Animals; Biological Transport; Brefeldin A; Cell Line; Cycloheximide; DNA; Electroporation; Endoplasmic Reticulum; Enzyme-Linked Immunosorbent Assay; Genes, Dominant; Genetic Vectors; Glutathione Transferase; Golgi Apparatus; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Insulin; Leptin; Membrane Glycoproteins; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mutation; Protein Isoforms; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Protein Transport; Qa-SNARE Proteins; Radioimmunoassay; Recombinant Proteins; Temperature; Time Factors; trans-Golgi Network; Transfection; Viral Envelope Proteins

2006
Direct effect of ghrelin on leptin production by cultured rat white adipocytes.
    Obesity (Silver Spring, Md.), 2006, Volume: 14, Issue:1

    Topics: Adipocytes; Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Ghrelin; Insulin; Leptin; Male; Peptide Hormones; Protein Synthesis Inhibitors; Rats; Rats, Inbred F344; RNA, Messenger

2006
Leptin biosynthetic pathway in white adipocytes.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2006, Volume: 84, Issue:2

    Topics: Adipocytes; Animals; Brefeldin A; Cycloheximide; Dactinomycin; Dioxoles; Immunohistochemistry; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Leptin; Male; Norepinephrine; Palmitic Acid; Rats; Rats, Wistar; RNA, Messenger; Subcellular Fractions

2006
Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue.
    Journal of lipid research, 2006, Volume: 47, Issue:9

    Topics: Adipocytes; Adipose Tissue; Animals; Blotting, Northern; Body Weight; Chloroquine; Cycloheximide; Insulin; Iodine Isotopes; Leptin; Leupeptins; Lysosomes; Male; Rats; Rats, Wistar; RNA, Messenger; Starvation; Sulfur Isotopes

2006
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Anilides; Animals; Carboxylic Ester Hydrolases; Cycloheximide; Dietary Fats; Dose-Response Relationship, Drug; Fluorenes; Gene Expression; Leptin; Lipase; Membrane Proteins; Mice; Mice, Inbred Strains; Mice, Knockout; PPAR gamma; Prostaglandin D2; Protein Biosynthesis; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones

2007
Octylphenol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor and extracellular signal-regulated kinase pathways.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Benzhydryl Compounds; Blood Glucose; Butadienes; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Fulvestrant; Half-Life; Leptin; MAP Kinase Kinase 1; Mice; Nitriles; Nucleic Acid Synthesis Inhibitors; Phenols; Phosphorylation; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Resistin; RNA Stability; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation

2008
Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism.
    Experimental cell research, 2008, Jul-01, Volume: 314, Issue:11-12

    Topics: 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Brefeldin A; Cell Differentiation; Culture Media; Cycloheximide; Glucose; Insulin; Leptin; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PPAR gamma; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Wortmannin

2008
Effects of galanin and leptin on gonadotropin-releasing hormone-stimulated luteinizing hormone release from the pituitary.
    Neuroendocrinology, 2009, Volume: 89, Issue:1

    Topics: Animals; Appetite; Cycloheximide; Female; Fertility; Galanin; Gonadotropin-Releasing Hormone; In Vitro Techniques; Leptin; Luteinizing Hormone; Metestrus; Nutritional Physiological Phenomena; Perfusion; Pituitary Gland, Anterior; Proestrus; Protein Synthesis Inhibitors; Rats; Rats, Wistar

2009
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Journal of biochemistry, 2009, Volume: 145, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin

2009
Superinduction of leptin mRNA in mouse hypothalamic neurons.
    Neuroreport, 2012, Oct-24, Volume: 23, Issue:15

    Topics: Animals; Anisomycin; Cell Line; Cycloheximide; Gene Expression Regulation; Hydroxamic Acids; Hypothalamus; Leptin; Mice; Neurons; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger

2012
Triiodothyronine increases mRNA and protein leptin levels in short time in 3T3-L1 adipocytes by PI3K pathway activation.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Chromones; Cycloheximide; Enzyme Activation; Leptin; Mice; Morpholines; Phosphatidylinositol 3-Kinase; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Time Factors; Triiodothyronine

2013
Leptin protects rat articular chondrocytes from cytotoxicity induced by TNF-α in the presence of cyclohexamide.
    Osteoarthritis and cartilage, 2015, Volume: 23, Issue:12

    Topics: Animals; Apoptosis; Blotting, Western; Cartilage, Articular; Chondrocytes; Cycloheximide; Flow Cytometry; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Knee Joint; Leptin; Membrane Potential, Mitochondrial; Microscopy, Confocal; Protein Synthesis Inhibitors; Rats; Tumor Necrosis Factor-alpha

2015