cycloheximide has been researched along with geldanamycin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbott, D; Ch'en, IL; Cuny, GD; Degterev, A; Gerber, SA; Germscheid, M; Hedrick, SM; Hitomi, J; Korkina, O; Lugovskoy, A; Teng, X; Wagner, G; Yuan, C; Yuan, J | 1 |
| Heruth, DP; Leyva, A; Rothberg, PG; Wetmore, LA | 1 |
| An, WG; Blagosklonny, MV; Neckers, L; Schulte, T; Sutphin, P; Whitesell, L | 1 |
| Dasgupta, G; Momand, J | 1 |
| Devin, A; Lewis, J; Lin, Y; Liu, ZG; Miller, A; Neckers, L; Rodriguez, Y | 1 |
| Kreuz, S; Scheurich, P; Siegmund, D; Wajant, H | 1 |
| De Maio, A; Vega, VL | 1 |
| Wang, E; Zhao, C | 1 |
| Bisht, KS; Gius, D; Isaacs, JS; Mimnaugh, EG; Neckers, L; Vos, M; Xu, W; Yuan, X | 1 |
| Nomura, M; Nomura, N; Yamashita, J | 1 |
| Dougherty, EJ; Pollenz, RS; Popat, J | 1 |
| Gerbin, CS; Landgraf, R | 1 |
| Albanesi, JP; Barylko, B; Jung, G; Lu, D; Shu, H; Yin, H | 1 |
| Asakura, N; Katou, S; Kojima, T; Mitsuhara, I; Seo, S | 1 |
| Kobayashi, Y; Masuda, S; Ohta, H; Tokaji, Y | 1 |
15 other study(ies) available for cycloheximide and geldanamycin
| Article | Year |
|---|---|
Identification of RIP1 kinase as a specific cellular target of necrostatins.
Topics: Animals; Apoptosis; Imidazoles; Mice; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship | 2008 |
Influence of protein tyrosine phosphorylation on the expression of the c-myc oncogene in cancer of the large bowel.
Topics: Benzoquinones; Cell Count; Cell Line; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Genistein; Half-Life; Humans; Isoflavones; Lactams, Macrocyclic; Novobiocin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; RNA, Messenger; Topoisomerase II Inhibitors; Tyrosine; Vanadates | 1995 |
Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo.
Topics: Acetylcysteine; Animals; Benzoquinones; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Detergents; Enzyme Inhibitors; Half-Life; Humans; Lactams, Macrocyclic; Leupeptins; Mice; Multienzyme Complexes; Mutation; Octoxynol; Polyethylene Glycols; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Quinones; Rats; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins | 1997 |
Geldanamycin prevents nuclear translocation of mutant p53.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Cell Line; Cell Nucleus; Cycloheximide; Cytoplasm; HSP90 Heat-Shock Proteins; Humans; Kinetics; Lactams, Macrocyclic; Mutagenesis, Site-Directed; Protein Binding; Protein Denaturation; Quinones; Tumor Suppressor Protein p53 | 1997 |
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation.
Topics: Apoptosis; Benzoquinones; Cell Survival; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Genes, Reporter; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Kinetics; Lactams, Macrocyclic; Leupeptins; Luciferases; NF-kappa B; Protein Serine-Threonine Kinases; Proteins; Quinones; Receptor-Interacting Protein Serine-Threonine Kinases; Recombinant Proteins; Transfection; Tumor Necrosis Factor-alpha | 2000 |
NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.
Topics: Antibodies, Monoclonal; Apoptosis; Benzoquinones; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; CD40 Antigens; Cell Line; Cycloheximide; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Interleukin-1; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Lactams, Macrocyclic; Leupeptins; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Quinones; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Geldanamycin treatment ameliorates the response to LPS in murine macrophages by decreasing CD14 surface expression.
Topics: Animals; Antibiotics, Antineoplastic; Benzoquinones; Blotting, Northern; Blotting, Western; Cell Line; Cell Membrane; Cycloheximide; Endoplasmic Reticulum; Escherichia coli; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; NF-kappa B; Protein Synthesis Inhibitors; Protein Transport; Quinones; RNA, Messenger; Time Factors | 2003 |
Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts.
Topics: Animals; Apoptosis; Benzoquinones; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspases; Cell Division; Cells, Cultured; Colorimetry; Cycloheximide; Cytochromes c; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice; Mitochondria; NIH 3T3 Cells; Quinones; Signal Transduction; Tumor Necrosis Factor-alpha | 2004 |
Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.
Topics: Antineoplastic Agents; Benzoquinones; Boronic Acids; Bortezomib; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Viral; Cycloheximide; Detergents; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteins; Pyrazines; Quinones; Repressor Proteins; Rifabutin; Solubility; Ubiquitins; Vacuoles | 2004 |
Geldanamycin-induced degradation of Chk1 is mediated by proteasome.
Topics: Base Sequence; Benzoquinones; Cell Line, Tumor; Checkpoint Kinase 1; Cycloheximide; DNA Primers; Half-Life; Humans; Hydrolysis; Lactams, Macrocyclic; Proteasome Endopeptidase Complex; Protein Kinases; Quinones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ubiquitin | 2005 |
Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ahb-1 receptor.
Topics: Animals; Benzoquinones; Cell Line; Cycloheximide; Dactinomycin; DNA; Lactams, Macrocyclic; Ligands; Mice; Polychlorinated Dibenzodioxins; Protein Binding; Protein Structure, Tertiary; Protein Transport; Quinones; Receptors, Aryl Hydrocarbon; Sulfuric Acid Esters; Transcription, Genetic; Transcriptional Activation | 2005 |
Geldanamycin selectively targets the nascent form of ERBB3 for degradation.
Topics: Benzoquinones; Brefeldin A; Cell Line, Tumor; Cycloheximide; ErbB Receptors; HSP90 Heat-Shock Proteins; Humans; Immunoprecipitation; Lactams, Macrocyclic; Microscopy, Fluorescence; Polymerase Chain Reaction; Protein Binding; Receptor, ErbB-2 | 2010 |
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90.
Topics: Animals; Benzoquinones; Chlorocebus aethiops; COS Cells; Cycloheximide; Electrophoresis, Polyacrylamide Gel; HEK293 Cells; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Immunoprecipitation; Lactams, Macrocyclic; Mass Spectrometry; Microscopy, Fluorescence; Minor Histocompatibility Antigens; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Stability; Rats | 2011 |
Transcriptome analysis of WIPK/SIPK-suppressed plants reveals induction by wounding of disease resistance-related genes prior to the accumulation of salicylic acid.
Topics: Benzoquinones; Cycloheximide; Disease Resistance; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Hot Temperature; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Nicotiana; Oligonucleotide Array Sequence Analysis; Plant Diseases; Plant Leaves; Protein Biosynthesis; Salicylic Acid; Suppression, Genetic; Transcriptional Activation; Up-Regulation | 2013 |
Mechanisms of induction of the stress-responsive transcription factors HsfA2 and DREB2A by 12-oxo-phytodienoic acid in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Benzoquinones; Cycloheximide; DNA-Binding Proteins; Fatty Acids, Unsaturated; Gene Expression Regulation, Plant; Heat Shock Transcription Factors; Heat-Shock Proteins; Lactams, Macrocyclic; Plant Proteins; Signal Transduction; Stress, Physiological; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2014 |