Page last updated: 2024-08-17

cycloheximide and etoposide

cycloheximide has been researched along with etoposide in 84 studies

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.38)18.7374
1990's39 (46.43)18.2507
2000's36 (42.86)29.6817
2010's7 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barrows, LR; Ireland, CM; Kokoshka, JM1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Chinnababu, B; Loka Reddy, V; Prakasham, RS; Purushotham Reddy, S; Rao, JV; Sankara Rao, P; Sudheer Kumar, B; Suresh Babu, K1
Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K1
Beardmore, C; D'Arpa, P; Liu, LF1
Kaufmann, SH1
Suciu, D1
Leblanc, J; Sikorska, M; Smith, C; Walker, PR; Whitfield, JF; Youdale, T1
Shionoya, S1
Chow, KC; Ross, WE1
Chow, KC; King, CK; Ross, WE1
Ciriolo, MR; Coppola, S; Ghibelli, L; Lafavia, E; Maresca, V; Rotilio, G1
Kato, M; Takada, S; Takayama, S1
Aarbakke, J; Endresen, PC; Prytz, PS1
Cooper, CS; Horwich, A; Huddart, RA; Robertson, D; Titley, J; Williams, GT1
Elvin, P; Hickman, JA; Wood, AC1
Farber, JL; Mizumoto, K; Rothman, RJ1
Azuma, Y; Kizaki, H; Onishi, Y1
Furukawa, S; Hayashi, K; Hayashi, Y; Kashiwagi, K; Kawashima, T; Nakajima, M; Ohta, J1
Bennett, MR; Evan, GI; Fanidi, A; Harrington, EA1
Goodhead, DT; Greaves, M; Griffiths, SD; Korsmeyer, SJ; Krajewski, S; Marsden, SJ; Reed, JC; Wright, EG1
Cohen, GM; Dinsdale, D; Ormerod, MG; Snowden, RT; Sun, XM1
Fulka, J; Moor, RM1
Bertoglio, J; Bréard, J; Issaad, C; Léglise, MC; Pallardy, M; Roger, R; Turhan, AG1
Daxenbichler, G; Lang, T; Marth, C; Müller-Holzner, E; Widschwendter, M1
Russev, G; Tsvetkov, L1
Pommier, Y; Shao, RG; Shimizu, T1
Kataoka, S; Naito, M; Noguchi, K; Tsuruo, T; Yonehara, S1
Piette, J; Piret, B1
Elsheikh, AS; Hishinuma, M; Kanagawa, H; Takahashi, Y1
Akiyama, Y; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, Ki1
Dragunow, M; MacGibbon, G; Saura, J1
Bacon, R; Jobson, T; Kitamura, M; Mooney, A; Savill, J1
Hanaoka, F; Okumura, K; Tanaka, A; Yamauchi, Y1
Carabillò, M; Giuliano, M; Lauricella, M; Tesoriere, G; Vassallo, E; Vento, R1
Athias, A; Bessede, G; Gambert, P; Gueldry, S; Lemaire, S; Lizard, G; Miguet, C; Monier, S; Solary, E; Sordet, O1
El-Deiry, WS; Meng, RD; Phillips, P1
Bushell, M; Clemens, MJ; Morley, SJ1
Golub, EI; Haaf, T; Raderschall, E1
Gollahon, KA; Kim, C; Potter, A; Rabinovitch, PS1
Engels, IH; Los, M; Rossmann, E; Schulze-Osthoff, K; Wesselborg, S1
Bettaieb, A; Bruey, JM; Droin, N; Eymin, B; Garrido, C; Ivarsson, M; Solary, E; Sordet, O1
Cohen, GM; Dinsdale, D; Zhuang, J1
Koistinen, P; Mäntymaa, P; Säily, M; Savolainen, E; Siitonen, T1
Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM1
Keogh, SA; Martin, SJ; Slee, EA1
Frost, V; Sinclair, AJ1
Bushell, M; Clemens, MJ; Flotow, H; Lloyd, RE; Marissen, WE; Morley, SJ; Poncet, D1
Brady, HP; Coffey, RN; Fitzpatrick, JM; Gibbons, NB; Watson, RW1
Kubelka, M; Moor, RM1
Baireddy, V; Strayer, DS; White, MK1
Cantoni, C; Daga, A; Lunardi, C; Millo, R; Oliveri, M; Puccetti, A1
d'Adda Di Fagagna, F; Freire, R; Hickson, ID; Jackson, SP; Pedrazzi, G; Stagljar, I; Wu, L1
Burnside, J; Cheng, G; Kurosaki, T; Kwan, R1
Heldebrant, MP; Kaufmann, SH; Meng, XW1
Budd, RC; Ito, M; Kataoka, T; Nagai, K; Tschopp, J1
Farber, JL; Karpinich, NO; Rothman, RJ; Russo, MA; Tafani, M1
Dong, YB; Elliott, MJ; McMasters, KM; Yang, HL1
Bach, FH; Berberat, PO; Brouard, S; Günther, L; Haga, M; Smith, RN; Soares, MP; Tobiasch, E1
Hatayama, T; Ishihara, K; Saito, Y; Yamagishi, N1
Cai, MM; Chen, C; Chen, S; Gu, JX; Hu, Y; Yan, J; Zhang, S; Zhang, SW; Zhu, XY1
Ball, KL; Dornan, D; Kelleher, M; Pamment, J; Ramsay, E1
Majerus, PW; Mochizuki, Y; Sun, Y1
Rikiishi, H; Sato, K; Shinohara, F; Suzuki, M; Takada, H; Taniguchi, T1
Moreau, M; Novak, S; Pothier, F; Saint-Cyr, A; Savard, C; Sirard, MA1
Berger, SA; Zhang, Y1
Fulka, H; Fulka, J; Loi, P; Nagai, T; Ptak, G1
Bor, MV; Nexø, E; Sørensen, BS; Tørring, N1
Chen, DF; Liu, MJ; Wang, Z; Wu, RC1
Chan, BC; Chan, JY; Ching, AK; Chow, SK; Chui, YL; Ho, TC; Ip, WK; Lam, CW; Lee, KK; Li, Q; Lim, PL; Wong, CK1
Choi, HY; Jeon, YK; Kim, CW; Kim, H; Kim, JE; Kim, YA; Kim, YN; Park, SO; Park, SS1
de Léséleuc, L; Denis, F1
Bennett, LN; Clarke, CA; Clarke, PR1
Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF1
Bai, J; Cederbaum, AI1
Mannherz, HG; Mazur, A; Meller, K; Theiss, C1
Abayasiriwardana, KS; Barbone, D; Broaddus, VC; Dansen, TB; Evan, GI; Hunt, AE; Kim, KU; Lee, KK; Vivo, C1
Aplin, AE; Hu, R1
Kopacek, J; Krizanova, O; Labudova, M; Lencesova, L; Ondrias, K; Pastorekova, S; Sirova, M1
Maquat, LE; Popp, MW1
Barteneva, NS; Vorobjev, IA1

Reviews

2 review(s) available for cycloheximide and etoposide

ArticleYear
Nucleus transfer in mammals: noninvasive approaches for the preparation of cytoplasts.
    Trends in biotechnology, 2004, Volume: 22, Issue:6

    Topics: Animals; Animals, Domestic; Centrifugation, Density Gradient; Cloning, Organism; Cycloheximide; Cytological Techniques; Demecolcine; Etoposide; Ionomycin; Mammals; Maturation-Promoting Factor; Metaphase; Mice; Micromanipulation; Microscopy, Fluorescence; Microscopy, Polarization; Nocodazole; Nuclear Transfer Techniques; Oocytes; Spindle Apparatus; Sucrose

2004
Multi-parametric imaging of cell heterogeneity in apoptosis analysis.
    Methods (San Diego, Calif.), 2017, 01-01, Volume: 112

    Topics: Algorithms; Apoptosis; Carbocyanines; Caspase 3; Caspase 7; Cycloheximide; Etoposide; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation; HeLa Cells; Humans; Image Cytometry; Jurkat Cells; Organometallic Compounds; Software; Staining and Labeling

2017

Other Studies

82 other study(ies) available for cycloheximide and etoposide

ArticleYear
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured

1996
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Isolation, semi-synthesis and bio-evaluation of spatane derivatives from the brown algae Stoechospermum marginatum.
    Bioorganic & medicinal chemistry letters, 2015, Jun-15, Volume: 25, Issue:12

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Phaeophyceae; Structure-Activity Relationship

2015
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells.
    Experimental cell research, 1992, Volume: 203, Issue:1

    Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Aphidicolin; Camptothecin; Cell Survival; Cricetinae; Cricetulus; Cycloheximide; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Etoposide; Mutagens; Nucleic Acids; RNA; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1990
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Amsacrine; Aphidicolin; Blotting, Western; Camptothecin; Colony-Forming Units Assay; Cycloheximide; Daunorubicin; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA Polymerase II; DNA Replication; Drug Synergism; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Mutagens; RNA; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured

1991
Reproductive death of Chinese hamster V79 cells after exposure to chemical inhibitors of DNA synthesis.
    The International journal of biochemistry, 1991, Volume: 23, Issue:11

    Topics: 4-Nitroquinoline-1-oxide; Amsacrine; Animals; Benzamides; Bisbenzimidazole; Cell Division; Cell Line; Cisplatin; Cricetinae; Cricetulus; Cycloheximide; DNA Replication; Etoposide; Gene Expression Regulation; In Vitro Techniques; Kinetics; Methylnitronitrosoguanidine; Puromycin; Teniposide; Transcription, Genetic; Uracil

1991
Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Amsacrine; Animals; Cycloheximide; Dactinomycin; Dexamethasone; DNA; Electrophoresis; Etoposide; Flow Cytometry; Lymphocytes; Mitosis; Rats; Rats, Inbred Strains; Teniposide; Thymus Gland; Time Factors; Topoisomerase II Inhibitors

1991
Etoposide inhibition of methylaminoisobutyric acid transport and its recovery in K562 cells.
    Leukemia research, 1991, Volume: 15, Issue:2-3

    Topics: Aminoisobutyric Acids; Biological Transport; Cell Division; Cycloheximide; Depression, Chemical; Etoposide; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Sodium; Tumor Cells, Cultured; Tumor Stem Cell Assay

1991
Topoisomerase-specific drug sensitivity in relation to cell cycle progression.
    Molecular and cellular biology, 1987, Volume: 7, Issue:9

    Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cell Survival; Cycloheximide; Diterpenes; DNA Damage; DNA Topoisomerases, Type II; Drug Administration Schedule; Etoposide; Interphase; Mice; Mitosis

1987
Abrogation of etoposide-mediated cytotoxicity by cycloheximide.
    Biochemical pharmacology, 1988, Mar-15, Volume: 37, Issue:6

    Topics: Animals; Cell Cycle; Cells, Cultured; Cycloheximide; DNA; DNA Damage; Etoposide; Humans; Mice; Protein Biosynthesis

1988
Non-oxidative loss of glutathione in apoptosis via GSH extrusion.
    Biochemical and biophysical research communications, 1995, Nov-02, Volume: 216, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Cell Line; Cycloheximide; Etoposide; Glutathione; Humans; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxidation-Reduction; Oxidative Stress; Puromycin

1995
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles.
    Journal of toxicology and environmental health, 1994, Volume: 42, Issue:1

    Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors

1994
A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle specificity through staining of F-actin and DNA.
    Cytometry, 1995, Jun-01, Volume: 20, Issue:2

    Topics: Actins; Apoptosis; Cell Cycle; Cycloheximide; Dactinomycin; DNA, Neoplasm; Etoposide; Evaluation Studies as Topic; Flow Cytometry; Humans; Leukemia; Microscopy, Confocal; Phalloidine; Propidium; Staining and Labeling; Tumor Cells, Cultured

1995
Programmed cell death in response to chemotherapeutic agents in human germ cell tumour lines.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:5

    Topics: Apoptosis; Cisplatin; Cycloheximide; Electrophoresis, Agar Gel; Etoposide; Flow Cytometry; Germinoma; Humans; Ionomycin; Male; Microscopy, Electron; Microscopy, Fluorescence; Testicular Neoplasms; Tumor Cells, Cultured

1995
Induction of apoptosis by anti-cancer drugs with disparate modes of action: kinetics of cell death and changes in c-myc expression.
    British journal of cancer, 1995, Volume: 71, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Cycloheximide; Dexamethasone; Etoposide; Formamides; Gene Expression; Genes, myc; Humans; Leukemia-Lymphoma, Adult T-Cell; Tumor Cells, Cultured

1995
Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide.
    Molecular pharmacology, 1994, Volume: 46, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkylating Agents; Animals; Apoptosis; Cell Division; Cycloheximide; DNA; Etoposide; Isoquinolines; L Cells; Methylnitrosourea; Mice; Piperazines; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Topoisomerase II Inhibitors

1994
bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Nucleic Acid Conformation; Piperazines; Razoxane; Thymus Gland; Topoisomerase I Inhibitors

1994
Etoposide induces programmed death in neurons cultured from the fetal rat central nervous system.
    Brain research, 1994, Apr-04, Volume: 641, Issue:2

    Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; DNA; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Kinetics; Neurons; Rats; Rats, Wistar; Time Factors

1994
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.
    The EMBO journal, 1994, Jul-15, Volume: 13, Issue:14

    Topics: Animals; Apoptosis; Cells, Cultured; Culture Media, Serum-Free; Cycloheximide; Cytokines; Estradiol; Etoposide; Fibroblasts; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Mesoderm; Mice; Platelet-Derived Growth Factor; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; Rats; Signal Transduction; Somatomedins; Thymidine

1994
Interleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis.
    The Journal of experimental medicine, 1994, Jun-01, Volume: 179, Issue:6

    Topics: Alpha Particles; Animals; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Cells, Cultured; Cisplatin; Clone Cells; Colony-Forming Units Assay; Cycloheximide; Dexamethasone; DNA Damage; Etoposide; Gene Transfer Techniques; Hematopoietic Stem Cells; Humans; Interleukin-7; Kinetics; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Plutonium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Spleen; Time Factors; X-Rays

1994
Changes in nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Apoptosis; Cell Nucleus; Cells, Cultured; Chromatin; Cycloheximide; Dactinomycin; DNA; Endonucleases; Etoposide; Flow Cytometry; Nucleosomes; Zinc

1994
Noninvasive chemical enucleation of mouse oocytes.
    Molecular reproduction and development, 1993, Volume: 34, Issue:4

    Topics: Animals; Cell Nucleus; Cycloheximide; Etoposide; Female; In Vitro Techniques; Maturation-Promoting Factor; Meiosis; Mesothelin; Mice; Nuclear Transfer Techniques; Oocytes

1993
BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells.
    Blood, 1996, Feb-01, Volume: 87, Issue:3

    Topics: Apoptosis; Camptothecin; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; DNA Damage; DNA, Neoplasm; Etoposide; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Humans; Hydrogen Peroxide; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia, Megakaryoblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Puromycin; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1996
Effects of Taxol on choriocarcinoma cells.
    American journal of obstetrics and gynecology, 1995, Volume: 173, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Etoposide; Female; Humans; Methotrexate; Paclitaxel; Pregnancy; Tumor Cells, Cultured; Uterine Neoplasms

1995
Decreased rates of replicon initiation in mammalian cells.
    European journal of biochemistry, 1996, Apr-15, Volume: 237, Issue:2

    Topics: Alkaloids; Animals; Antineoplastic Agents; Benzamides; Cisplatin; Cycloheximide; DNA Replication; DNA, Neoplasm; Down-Regulation; Etoposide; Friend murine leukemia virus; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Replicon; Signal Transduction; Staurosporine; Tumor Cells, Cultured

1996
Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53.
    Experimental cell research, 1996, Sep-15, Volume: 227, Issue:2

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Brefeldin A; Camptothecin; Cell-Free System; Cyclin B; Cyclin B1; Cyclins; Cycloheximide; Cyclopentanes; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; HL-60 Cells; HT29 Cells; Humans; Mutation; Protein Synthesis Inhibitors; Staurosporine; Time Factors; Tumor Suppressor Protein p53

1996
A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:10

    Topics: Antibodies; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cycloheximide; DNA; Etoposide; fas Receptor; Genes, Recessive; Humans; Hybrid Cells; Monocytes; Mutation; Phenotype; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptors, Tumor Necrosis Factor; Signal Transduction; Tumor Necrosis Factor-alpha

1995
Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells.
    Nucleic acids research, 1996, Nov-01, Volume: 24, Issue:21

    Topics: Antioxidants; Camptothecin; Cell Line; Cycloheximide; Dactinomycin; Daunorubicin; DNA; DNA Damage; DNA Topoisomerases, Type I; Etoposide; HIV-1; NF-kappa B; Nucleic Acid Synthesis Inhibitors; Poly(ADP-ribose) Polymerase Inhibitors; Topoisomerase I Inhibitors; Transcriptional Activation; Virus Activation

1996
Developmental ability of mouse late 2-cell stage blastomeres fused to chemically enucleated oocytes in vitro.
    The Journal of veterinary medical science, 1997, Volume: 59, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blastomeres; Cell Fusion; Cell Nucleus; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Drug Combinations; Embryonic and Fetal Development; Etoposide; Female; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred ICR; Oocytes; Protein Synthesis Inhibitors

1997
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide.
    Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays

1997
Etoposide-induced PC12 cell death: apoptotic morphology without oligonucleosomal DNA fragmentation or dependency upon de novo protein synthesis.
    Brain research. Molecular brain research, 1997, Volume: 48, Issue:2

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cycloheximide; Dactinomycin; DNA Fragmentation; Etoposide; Immunohistochemistry; Nerve Growth Factors; Nucleosomes; PC12 Cells; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats

1997
Cytokines promote glomerular mesangial cell survival in vitro by stimulus-dependent inhibition of apoptosis.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Oct-15, Volume: 159, Issue:8

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Line; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cycloheximide; Cytokines; Etoposide; fas Receptor; Fibroblast Growth Factor 2; Glomerular Mesangium; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kidney Cortex; Paracrine Communication; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats

1997
A mutant strain of mouse FM3A cells defective in apoptotic DNA fragmentation.
    Biochemical and biophysical research communications, 1998, Feb-13, Volume: 243, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Cycloheximide; DNA Damage; DNA Fragmentation; Etoposide; Flow Cytometry; Kinetics; Mice; Phosphatidylserines; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ultraviolet Rays; X-Rays

1998
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:8

    Topics: Amsacrine; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dactinomycin; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Insulin-Like Growth Factor Binding Protein 3; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:15

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Caspases; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; Etoposide; Fatty Acids, Unsaturated; Free Radicals; Glutathione; Humans; Ketocholesterols; Oxidation-Reduction; Reactive Oxygen Species; U937 Cells

1998
p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin.
    International journal of oncology, 1999, Volume: 14, Issue:1

    Topics: Animals; Apoptosis; Carrier Proteins; Cell Cycle Proteins; Cycloheximide; DNA; DNA Damage; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Etoposide; Humans; Mice; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines.
    Oncogene, 1998, Dec-03, Volume: 17, Issue:22

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspase Inhibitors; Caspases; Culture Media, Serum-Free; Cycloheximide; Etoposide; Eukaryotic Initiation Factor-4E; fas Receptor; Half-Life; Humans; Jurkat Cells; Lymphoma; Molecular Weight; Neoplasm Proteins; Oligopeptides; Peptide Initiation Factors; Poly(A)-Binding Proteins; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; RNA-Binding Proteins; Sirolimus; Tumor Cells, Cultured

1998
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Animals; Cell Cycle; Cell Line; Cell Nucleus; Chromatin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Single-Stranded; Etoposide; Fibroblasts; Gamma Rays; Humans; Kinetics; Mammals; Meiosis; Mitomycin; Nuclear Proteins; Rats; Recombinant Proteins; Sensitivity and Specificity; Xeroderma Pigmentosum

1999
Apoptotic human lymphocytes have diminished CD4 and CD8 receptor expression.
    Cellular immunology, 1999, Apr-10, Volume: 193, Issue:1

    Topics: Apoptosis; CD3 Complex; CD4 Antigens; CD8 Antigens; Cycloheximide; Etoposide; Humans; Lymphocytes; Necrosis; Transglutaminases

1999
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.
    Blood, 1999, May-01, Volume: 93, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Caspase 8; Caspase 9; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Daunorubicin; Doxorubicin; Enzyme Activation; Etoposide; Fas Ligand Protein; fas Receptor; HeLa Cells; Humans; Jurkat Cells; Membrane Glycoproteins; Mitomycin; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tumor Cells, Cultured

1999
Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells.
    Cell death and differentiation, 1999, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Carcinogens; Caspase 2; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Adhesion; Cell Differentiation; Cycloheximide; Cytochrome c Group; Enzyme Precursors; Etoposide; Fas Ligand Protein; Humans; Membrane Glycoproteins; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; U937 Cells; Vinblastine

1999
Redistribution of cytochrome c precedes the caspase-dependent formation of ultracondensed mitochondria, with a reduced inner membrane potential, in apoptotic monocytes.
    The American journal of pathology, 1999, Volume: 155, Issue:2

    Topics: Actins; Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytoskeleton; Etoposide; Flow Cytometry; Golgi Apparatus; Humans; Immunohistochemistry; Membrane Potentials; Mitochondria; Monocytes; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Tumor Cells, Cultured

1999
Etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells.
    Leukemia research, 2000, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cycloheximide; Etoposide; Fas Ligand Protein; fas Receptor; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Tumor Cells, Cultured

2000
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin

2000
Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release.
    Cell death and differentiation, 2000, Volume: 7, Issue:6

    Topics: Animals; Apoptosis; Aspartic Acid; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspases; Catalysis; Cell-Free System; Cycloheximide; Cytochrome c Group; Enzyme Inhibitors; Etoposide; Humans; Jurkat Cells; Mice; Mitochondria, Liver; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured; Ultraviolet Rays

2000
p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis.
    Oncogene, 2000, Jun-22, Volume: 19, Issue:27

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; B-Lymphocytes; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; Down-Regulation; Etoposide; fas Receptor; Humans; Jurkat Cells; Microtubule-Associated Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proteins; Signal Transduction; T-Lymphocytes; Tumor Suppressor Proteins

2000
Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage.
    Cell death and differentiation, 2000, Volume: 7, Issue:7

    Topics: Apoptosis; Blotting, Western; Burkitt Lymphoma; Caspase 3; Caspases; Cell Cycle; Cycloheximide; DNA; Endopeptidases; Etoposide; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Humans; Nucleic Acid Synthesis Inhibitors; Peptide Chain Initiation, Translational; Peptide Fragments; Peptide Initiation Factors; Protein Biosynthesis; Protein Synthesis Inhibitors; Tumor Cells, Cultured

2000
Heat-shock proteins inhibit induction of prostate cancer cell apoptosis.
    The Prostate, 2000, Sep-15, Volume: 45, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Blotting, Western; Cycloheximide; Etoposide; Glutathione; Glutathione Transferase; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Kinetics; Male; Maleates; Molecular Chaperones; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nucleic Acid Synthesis Inhibitors; Prostatic Neoplasms; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Tumor Cells, Cultured

2000
Behaviour of mouse primary spermatocyte nuclei after fusion to enucleated metaphase II oocytes.
    Zygote (Cambridge, England), 2000, Volume: 8, Issue:4

    Topics: Animals; Cell Division; Cell Fusion; Cell Nucleus; Cycloheximide; DNA Replication; Etoposide; Female; Karyotyping; Male; Metaphase; Mice; Mice, Inbred Strains; Oocytes; Sexual Maturation; Spermatocytes; Testis

2000
Natural protection from apoptosis by surfactant protein A in type II pneumocytes.
    Experimental cell research, 2001, Feb-15, Volume: 263, Issue:2

    Topics: Animals; Apoptosis; Carrier Proteins; Cell Separation; Cells, Cultured; Cycloheximide; Dexamethasone; Enzyme Inhibitors; Etoposide; Female; Flow Cytometry; Glucocorticoids; Glycoproteins; Humans; In Situ Nick-End Labeling; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Signal Transduction; Staurosporine; Ultraviolet Rays

2001
DNase I mediates internucleosomal DNA degradation in human cells undergoing drug-induced apoptosis.
    European journal of immunology, 2001, Volume: 31, Issue:3

    Topics: Apoptosis; Cell Nucleus; Cell Survival; Cycloheximide; Dactinomycin; Deoxyribonuclease I; DNA; DNA Fragmentation; Etoposide; fas Receptor; Gene Targeting; Humans; Jurkat Cells; Kinetics; Nucleosomes; Paclitaxel; Transfection; Tumor Cells, Cultured

2001
Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha.
    Nucleic acids research, 2001, Aug-01, Volume: 29, Issue:15

    Topics: Adenosine Triphosphatases; Apoptosis; Bloom Syndrome; Caspase 3; Caspases; Cycloheximide; DNA Helicases; DNA Topoisomerases, Type I; Etoposide; HeLa Cells; HL-60 Cells; Humans; Models, Biological; Molecular Weight; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; RecQ Helicases; Tumor Necrosis Factor-alpha

2001
MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.
    Molecular and cellular biology, 2001, Volume: 21, Issue:21

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Southern; Blotting, Western; Cell Cycle; Cell Line; Chickens; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Etoposide; G2 Phase; Gene Library; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Microtubules; Mitogen-Activated Protein Kinases; Mitosis; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Signal Transduction; Thymidine; Time Factors; Transfection; Vinblastine

2001
Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain.
    The Journal of biological chemistry, 2002, Feb-01, Volume: 277, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Antigens, CD; Apoptosis; Apoptosis Regulatory Proteins; Binding Sites; Camptothecin; Carrier Proteins; Cell Line; Cycloheximide; Etoposide; fas Receptor; Fas-Associated Death Domain Protein; Gamma Rays; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Kinetics; Membrane Glycoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells.
    Experimental cell research, 2002, Feb-15, Volume: 273, Issue:2

    Topics: Animals; Apoptosis; Camptothecin; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase Inhibitors; Cell Membrane; Cycloheximide; Down-Regulation; Doxorubicin; Etoposide; Fas Ligand Protein; fas Receptor; Gene Expression; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mitomycin; Protein Synthesis Inhibitors; Thymoma; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Up-Regulation

2002
The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c.
    The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19

    Topics: Androstadienes; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Line; Cell Survival; Cells, Cultured; Chloride Channels; Cycloheximide; Cytochrome c Group; Cytosol; Diuretics; DNA Damage; Enzyme Inhibitors; Etoposide; Fibroblasts; Furosemide; Mice; Mitochondria; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Synthesis Inhibitors; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Time Factors; Transfection; Tumor Suppressor Protein p53; Ubiquinone; Up-Regulation; Wortmannin

2002
Adenovirus-mediated E2F-1 gene transfer sensitizes melanoma cells to apoptosis induced by topoisomerase II inhibitors.
    Cancer research, 2002, Mar-15, Volume: 62, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Proteins; Cisplatin; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA-Binding Proteins; Doxorubicin; Drug Synergism; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Etoposide; Fluorouracil; Genetic Therapy; Genetic Vectors; Humans; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Proliferating Cell Nuclear Antigen; Purines; Roscovitine; Topoisomerase II Inhibitors; Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function/survival after transplantation.
    Diabetes, 2002, Volume: 51, Issue:4

    Topics: Animals; Apoptosis; Carbon Monoxide; Cell Survival; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Etoposide; Graft Survival; Guanylate Cyclase; Insulinoma; Islets of Langerhans; Islets of Langerhans Transplantation; Kinetics; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Pancreatic Neoplasms; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Hsp105alpha enhances stress-induced apoptosis but not necrosis in mouse embryonal f9 cells.
    Journal of biochemistry, 2002, Volume: 132, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Line; Cell Survival; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Embryo, Mammalian; Enzyme Precursors; Etoposide; Hot Temperature; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proteins

2002
Different effects of p58PITSLRE on the apoptosis induced by etoposide, cycloheximide and serum-withdrawal in human hepatocarcinoma cells.
    Molecular and cellular biochemistry, 2002, Volume: 238, Issue:1-2

    Topics: Apoptosis; Blood Volume; Cell Death; Culture Media, Serum-Free; Cyclin-Dependent Kinases; Cycloheximide; Etoposide; Female; Humans; In Situ Nick-End Labeling; Liver; Liver Neoplasms; Luminescent Measurements; Protein Kinases; Protein Serine-Threonine Kinases; Tumor Cells, Cultured

2002
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Oncogene, 2002, Nov-07, Volume: 21, Issue:51

    Topics: Androstadienes; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Fibroblasts; Gamma Rays; Genes, p53; Genes, Reporter; Humans; Interferon Regulatory Factor-1; Melanoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Poly I-C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2002
Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Antigens, CD; Apoptosis; Blotting, Northern; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Line; Cycloheximide; DNA; Dose-Response Relationship, Drug; Etoposide; HeLa Cells; Humans; Phosphotransferases (Alcohol Group Acceptor); Poly(ADP-ribose) Polymerases; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Protein Transport; Proteins; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Time Factors; TNF Receptor-Associated Factor 1; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha

2003
Dual role of NF-kappaB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide.
    Leukemia research, 2004, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cycloheximide; Dactinomycin; Drug Therapy, Combination; Enzyme Inhibitors; Etoposide; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Lipopolysaccharides; NF-kappa B; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tosyllysine Chloromethyl Ketone; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein

2004
Comparison of bulk enucleation methods for porcine oocytes.
    Molecular reproduction and development, 2004, Volume: 67, Issue:1

    Topics: Animals; Cell Fractionation; Cell Nucleus; Cloning, Organism; Cycloheximide; Etoposide; Maturation-Promoting Factor; Micromanipulation; Nucleic Acid Synthesis Inhibitors; Oocytes; Protein Kinases; Protein Synthesis Inhibitors; Swine; Time Factors

2004
Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Area Under Curve; Calcium; Cell Death; Cell Line, Tumor; Cycloheximide; Dithiothreitol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Econazole; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Etoposide; Fas Ligand Protein; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Phenotype; Ribosomes; Thapsigargin; Time Factors; Tunicamycin

2004
The DNA damaging agent VP16 induces the expression of a subset of ligands from the EGF system in bladder cancer cells, whereas none of the four EGF receptors are induced.
    Molecular and cellular biochemistry, 2004, Volume: 260, Issue:1-2

    Topics: Amphiregulin; Antineoplastic Agents, Phytogenic; Betacellulin; Cell Line, Tumor; Cell Membrane; Cycloheximide; Dose-Response Relationship, Drug; EGF Family of Proteins; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Etoposide; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Protein Synthesis Inhibitors; RNA, Messenger; Transforming Growth Factor alpha; Urinary Bladder Neoplasms

2004
Dual effects of cycloheximide on U937 apoptosis induced by its combination with VP-16.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cycloheximide; Dose-Response Relationship, Drug; Etoposide; Humans; U937 Cells

2004
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.
    The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50

    Topics: Apoptosis; Base Sequence; Cell Nucleus; Cycloheximide; Cytosol; Etoposide; fas Receptor; Gene Expression; HeLa Cells; Humans; Jurkat Cells; Mitochondria; Nerve Tissue Proteins; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; RNA, Small Interfering; Transfection; Tumor Necrosis Factor-alpha

2004
Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma.
    Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:7

    Topics: Antibodies, Monoclonal; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cell Proliferation; Cell Survival; Cycloheximide; Death-Associated Protein Kinases; Decitabine; Down-Regulation; Enzyme Activation; Etoposide; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Killer Cells, Natural; Lymphoma, T-Cell, Peripheral; Protein Synthesis Inhibitors

2005
Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
    Cell death and differentiation, 2006, Volume: 13, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cell Line; Cycloheximide; DNA Damage; DNA-Binding Proteins; Endoplasmic Reticulum; Etoposide; Fas Ligand Protein; Fibroblasts; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Membrane Glycoproteins; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thapsigargin; Transcription Factors; Transfection; Tumor Necrosis Factors

2006
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.
    The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Animals; Apoptosis; Aspartic Acid; Binding Sites; Caspase 7; Caspases; Cell Cycle; Cell Line; Cell Nucleus; Cell-Free System; Checkpoint Kinase 1; Cycloheximide; Cytosol; DNA; DNA Replication; Dose-Response Relationship, Drug; Drosophila; Etoposide; HeLa Cells; Humans; Immunoprecipitation; Jurkat Cells; Mice; Models, Biological; Molecular Sequence Data; Oligonucleotides; Phosphorylation; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Xenopus; Xenopus Proteins

2005
The extracellular release of HMGB1 during apoptotic cell death.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha

2006
Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Actins; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cycloheximide; Dactinomycin; DNA Fragmentation; Doxorubicin; Etoposide; Flow Cytometry; Humans; Phosphorylation; Protein Synthesis Inhibitors; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Trypan Blue; Tumor Suppressor Protein p53

2006
Changes in gap junction organization and decreased coupling during induced apoptosis in lens epithelial and NIH-3T3 cells.
    Experimental cell research, 2007, Jan-01, Volume: 313, Issue:1

    Topics: Animals; Apoptosis; Caspases; Cattle; Cells, Cultured; Connexin 43; Cycloheximide; Epithelial Cells; Etoposide; Gap Junctions; Lens, Crystalline; Mice; NIH 3T3 Cells; Phosphorylation; Puromycin; Staurosporine

2007
Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:10

    Topics: Anisomycin; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Combined Modality Therapy; Cycloheximide; Drug Synergism; Electrophoresis, Gel, Two-Dimensional; Etoposide; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Ligands; Membrane Proteins; Mesothelioma; Phosphorylation; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2007
alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.
    Pigment cell & melanoma research, 2010, Volume: 23, Issue:2

    Topics: alpha-Crystallin B Chain; Bleomycin; Butadienes; Cells, Cultured; Cyclin D1; Cycloheximide; DNA Damage; Etoposide; Humans; Leupeptins; Melanocytes; Melanoma; Mutant Proteins; Mutation; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Tetracycline

2010
Apoptosis induced clustering of IP(3)R1 in nuclei of non-differentiated PC12 cells.
    Journal of cellular physiology, 2011, Volume: 226, Issue:12

    Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; bcl-2-Associated X Protein; Boron Compounds; Calcium; Camptothecin; Caspase 3; Cell Differentiation; Cell Nucleus; Cycloheximide; Dactinomycin; Dexamethasone; Etoposide; Inositol 1,4,5-Trisphosphate Receptors; PC12 Cells; Permeability; Rats; RNA, Messenger; Time Factors; Up-Regulation

2011
Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics.
    Nature communications, 2015, Mar-26, Volume: 6

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Codon, Nonsense; Cycloheximide; Doxorubicin; Etoposide; HEK293 Cells; HeLa Cells; Humans; Jurkat Cells; MCF-7 Cells; Nonsense Mediated mRNA Decay; Protein Synthesis Inhibitors; RNA Helicases; RNA, Messenger; Trans-Activators

2015