Page last updated: 2024-08-17

cycloheximide and cyclosporine

cycloheximide has been researched along with cyclosporine in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's46 (65.71)18.2507
2000's16 (22.86)29.6817
2010's6 (8.57)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Clardy, J; Derbyshire, ER; Mota, MM; Prudêncio, M1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Brittinger, G; Michel, MC; Sykora, J; Trenn, G1
Smyth, MJ1
Ameisen, JC; Capron, A; Groux, H; Monté, D; Mouton, Y; Torpier, G1
Gollapudi, S; Gupta, S; Tsuruo, T1
Bommhardt, U; Sadlack, B; Schimpl, A1
Choi, GH; Larson, TG; Nuss, DL1
Chen, CA; Collins, JL; Herzog, TJ; Mutch, DG1
Borger, P; Dokter, WH; Halie, MR; Hendriks, D; van der Horst, I; Vellenga, E1
Hata, D; Heike, T; Higaki, Y; Horiguchi, Y; Ishigami, T; Katamura, K; Kim, KM; Mayumi, M; Mikawa, H1
Appleby, P; Cooper, KL; Titchmarsh, SA; Tomkins, PT; Webber, DG1
Henttinen, T; Hurme, M; Levy, DE; Silvennoinen, O1
Fields, P; Fitch, FW; Gajewski, TF1
Alileche, A; Azzarone, B; Cohen, EP; Han, D; Jasmin, C; Kim, TS; Plaisance, S; Pottin-Clemenceau, C; Rubinstein, E1
Haynes, BF; Ware, RE1
Matsui, T; Nakao, Y; Natazuka, T; Saida, T; Umemiya-Okada, T1
Renfro, JL; Sussman-Turner, C1
Fresno, M; Mazana, J; Pimentel-Muiños, FX1
Dokter, WH; Stulp, BK; Van Straaten, JF; Vellenga, E1
Batiuk, TD; Halloran, PF; Pazderka, F1
Kroemer, G; Martínez, C1
Naora, H; Young, IG1
Benz, EJ; Chambers, SK; Gilmore-Hebert, M; Kacinski, BM; Rodov, S; Wang, Y1
Dokter, WH; Esselink, MT; Halie, MR; Sierdsema, SJ; Vellenga, E1
Cockfield, SM; Halloran, PF; Ramassar, V1
Larson, TG; Nuss, DL1
Buss, WC; Stepanek, J1
Bravo, R; Kroczek, RA; Mages, HW; Rilke, O; Stamminger, T1
Campbell, HD; Wang, Y; Young, IG1
Borger, P; Kauffman, HF; Postma, DS; Vellenga, E1
Girdlestone, J; Wing, M1
Debatin, KM; Friesen, C; Herr, I; Krammer, PH1
Aarden, LA; Bakker, A; Civil, A; Doerre, S; Rensink, I; Verweij, CL1
Lin, J; Raffaniello, RD; Raufman, JP1
Hellewell, PG; Teixeira, MM; Williams, TJ1
Metcalfe, DD; Oh, CK; Rumsaeng, V; Vliagoftis, H1
Cory, S; Huang, DC; Strasser, A1
Finn, PW; Guan, G; He, H; Listman, J; Perkins, DL; Wang, Y; Wang, Z1
Sewell, WA; Valentine, JE1
Cristillo, AD; Forsdyke, DR; Heximer, SP; Russell, L1
Nuss, DL; Wang, P1
Berrih-Aknin, S; Bidault, J; Moulian, N; Planché, C1
Ishaq, M; Natarajan, V; Zhang, YM1
Godar, DE1
Bandyopadhyay, A; Bandyopadhyay, J; Choi, HS; Chung, J; Kwon, HB1
Boots, AM; Rijnders, AW; Steenbakkers, PG1
Arellano, JL; de Cabo, MR; García, JE; López, AJ; López, AM; Losada, JP; Rodríguez, FM; Sarmiento, RG1
Cho, SH; Demissie-Sanders, S; Filler, SA; Oh, CK; Tam, SW1
Cho, SH; Filler, SG; Oh, CK1
Busányová, K; Drobná, Z; Ferencík, M; Horáková, K; Seemannová, Z; Sovcíková, A; Syrová, D1
Griepp, RB; Hagl, C; Insolia, S; Nandor, S; Spielvogel, D; Tatton, NA1
Bodian, CA; Griepp, RB; Hagl, C; Shiang, HH; Spielvogel, D; Tatton, NA; Weisz, DJ; Zhang, N1
Hamanaka, N; Hiraga, K; Oda, K; Sugi, H; Wanigasekera, A1
Annamalai, K; Boogaerts, MA; Huylebroeck, D; Pype, S; Remacle, JE; Srahna, M; Vandenberghe, P1
Ishii, M; Kiuchi, Y; Shimizu, S; Shiota, K; Yamamoto, S; Yamamoto, T1
Skulachev, VP1
Beppu, K; Hirano, K; Ihara, E; Kanaide, H; Katano, M; Matsunaga, H; Morisaki, T; Tanaka, M; Uchiyama, A1
Levin, LA; Lieven, CJ; Vrabec, JP1
Ducreux, S; Girard, T; Müller, C; Muntoni, F; Quinlivan, R; Restagno, G; Sewry, C; Treves, S; Zorzato, F1
Canellada, A; Cano, E; Redondo, JM; Sánchez-Ruiloba, L; Zafra, F1
Bertani, F; Farber, JL; Indelicato, M; Karpinich, NO; Pucci, B; Russo, MA; Tafani, M1
Gómez-Crisóstomo, NP; López-Marure, R; Martínez-Abundis, E; Zapata, E; Zazueta, C1
Crotti, TN; Faralli, JA; Filla, MS; Gagen, D; Peters, DM1
Chiu, RH; Guo, M; Ha, A; Sun, S; Yokoyama, KK; Zhang, JB1
Bram, RJ; Gundelach, JH; Wang, L1
Bal, NV; Balaban, PM; Maltsev, AV1

Reviews

3 review(s) available for cycloheximide and cyclosporine

ArticleYear
Multidrug resistant gene 1 product in human T cell subsets: role of protein kinase C isoforms and regulation by cyclosporin A.
    Advances in experimental medicine and biology, 1992, Volume: 323

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cycloheximide; Cyclosporine; Dactinomycin; Drug Resistance; Gene Expression Regulation; Humans; Isoenzymes; Lymphocyte Activation; Membrane Glycoproteins; Mice; Models, Biological; Phytohemagglutinins; Protein Kinase C; T-Lymphocyte Subsets

1992
Pharmacological inhibition of programmed lymphocyte death.
    Immunology today, 1994, Volume: 15, Issue:5

    Topics: Animals; Apoptosis; Cycloheximide; Cyclosporine; Humans; Hydroxyquinolines; Lymphocytes; Mifepristone; Proto-Oncogenes; Tretinoin

1994
Programmed death in yeast as adaptation?
    FEBS letters, 2002, Sep-25, Volume: 528, Issue:1-3

    Topics: Adaptation, Physiological; Apoptosis; Caspases; Cycloheximide; Cyclosporine; Mating Factor; Mitochondria; Models, Biological; Peptides; Pheromones; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2002

Other Studies

67 other study(ies) available for cycloheximide and cyclosporine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22

    Topics: Animals; Anopheles; Antimalarials; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Inhibitory Concentration 50; Insect Vectors; Life Cycle Stages; Liver; Malaria; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Treatment Outcome

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Functional and biochemical characterization of a calcium-ionophore-induced state of unresponsiveness in a cytolytic T cell clone.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Mar-01, Volume: 148, Issue:5

    Topics: Calcimycin; Calcium; Clone Cells; Cycloheximide; Cyclosporine; Exocytosis; Humans; Interleukin-2; Lymphocyte Activation; Phosphatidylinositols; Proteins; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic

1992
Mechanisms of cytotoxicity used by human peripheral blood T-cell subsets.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Bucladesine; CD4 Antigens; CD8 Antigens; Cholera Toxin; Cycloheximide; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Egtazic Acid; Emetine; Humans; Lymphocyte Activation; Mitomycin; T-Lymphocyte Subsets; Tumor Necrosis Factor-alpha

1992
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.
    The Journal of experimental medicine, 1992, Feb-01, Volume: 175, Issue:2

    Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Death; Cycloheximide; Cyclosporine; Electrophoresis, Agar Gel; Enterotoxins; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lymphocyte Activation; Male; Mitogens; Receptors, Antigen, T-Cell, alpha-beta

1992
Quantitative and qualitative differences in IL-2 and IL-4 expression in primary and secondary T cell stimulation.
    International immunology, 1992, Volume: 4, Issue:4

    Topics: Animals; Calcium; Cycloheximide; Cyclosporine; Enzyme Activation; Interleukin-2; Interleukin-4; Lymphocyte Activation; Methylmannosides; Protein Kinase C; RNA; T-Lymphocytes

1992
Regulatory pathways governing modulation of fungal gene expression by a virulence-attenuating mycovirus.
    The EMBO journal, 1992, Volume: 11, Issue:12

    Topics: Ascomycota; Base Sequence; Calcium; Cycloheximide; Cyclosporine; DNA, Single-Stranded; Electrophoresis, Agar Gel; Gene Expression Regulation, Fungal; Gene Expression Regulation, Viral; Inositol Phosphates; Laccase; Lithium; Molecular Sequence Data; Oxidoreductases; Promoter Regions, Genetic; RNA Viruses; Transcription, Genetic; Virulence

1992
The effects of cyclosporin A on the lysis of ovarian cancer cells by cisplatin or adriamycin.
    Gynecologic oncology, 1992, Volume: 47, Issue:1

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cisplatin; Cycloheximide; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance; Emetine; Female; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil

1992
Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level.
    Blood, 1992, Dec-01, Volume: 80, Issue:11

    Topics: Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Cycloheximide; Cyclosporine; Dactinomycin; Gene Expression Regulation; Humans; Interleukin-4; Receptors, Interleukin-4; Receptors, Mitogen; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1992
Anti-IgM antibody-induced cell death in a human B lymphoma cell line, B104, represents a novel programmed cell death.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jan-15, Volume: 148, Issue:2

    Topics: Antibodies, Anti-Idiotypic; Calcium; Cell Death; Cycloheximide; Cyclosporine; Dactinomycin; DNA; DNA Damage; Humans; Immunoglobulin M; Lymphoma, B-Cell; Tumor Cells, Cultured

1992
BTS 71 412: in vitro profile of a novel pyrazolinone immunosuppressant.
    International journal of immunopharmacology, 1995, Volume: 17, Issue:5

    Topics: Animals; Antibody Formation; Antigens; Cell Line; Cells, Cultured; Cycloheximide; Cyclosporine; Cytokines; Dexamethasone; Dose-Response Relationship, Immunologic; Female; Hemocyanins; Immunosuppressive Agents; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocyte Subsets; Lymphocytes; Macrophage Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyrazoles; Pyrazolones; Spleen

1995
Activation of the signal transducer and transcription (STAT) signaling pathway in a primary T cell response. Critical role for IL-6.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Nov-15, Volume: 155, Issue:10

    Topics: Base Sequence; Cycloheximide; Cyclosporine; Humans; Interleukin-6; Lymphocyte Activation; Molecular Sequence Data; Signal Transduction; T-Lymphocytes; Trans-Activators; Transcription, Genetic

1995
Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.
    European journal of immunology, 1995, Volume: 25, Issue:7

    Topics: Animals; Calcium; CD3 Complex; Clonal Anergy; Cycloheximide; Cyclosporine; Enzyme Induction; In Vitro Techniques; Lymphocyte Activation; Mice; Mice, Inbred DBA; Protein Biosynthesis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Signal Transduction; Th1 Cells

1995
Non random activation of endogenous interleukin-2, (IL-2), IL-2 receptor alpha and IL-2 receptor beta genes after transfection of mouse fibroblasts with a cDNA for the alpha chain of the human IL-2 receptor.
    European journal of immunology, 1995, Volume: 25, Issue:7

    Topics: Animals; Blotting, Northern; Cell Line; Cycloheximide; Cyclosporine; DNA Primers; Fibroblasts; Gene Expression Regulation; Genes, MHC Class I; H-2 Antigens; Humans; Interleukin-2; Mice; Polymerase Chain Reaction; Receptors, Interleukin-2; RNA, Messenger; Transcriptional Activation; Transfection

1995
T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms.
    International immunology, 1993, Volume: 5, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Base Sequence; CD3 Complex; Cells, Cultured; Cycloheximide; Cyclosporine; Gene Expression Regulation; Humans; Ionomycin; Molecular Sequence Data; Phytohemagglutinins; RNA Processing, Post-Transcriptional; RNA, Messenger; T-Lymphocytes; Transcription, Genetic

1993
FK506 and cyclosporin a regulate proliferation and proto-oncogene expression in HTLV-1-associated myelopathy/tropical-spastic-paraparesis-derived T cells.
    International journal of cancer, 1993, May-08, Volume: 54, Issue:2

    Topics: Cell Division; Cycloheximide; Cyclosporine; Gene Expression; Genes, fos; Genes, jun; Genes, myc; Humans; Interleukin-2; Paraparesis, Tropical Spastic; Proto-Oncogene Mas; Proto-Oncogenes; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tacrolimus

1993
Heat-shock-stimulated transepithelial daunomycin secretion by flounder renal proximal tubule primary cultures.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Cycloheximide; Cyclosporine; Daunorubicin; Epithelial Cells; Epithelium; Flounder; Hot Temperature; Immunohistochemistry; Kidney Tubules, Proximal; Kinetics; Microvilli; p-Aminohippuric Acid; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil; Vinblastine

1995
Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: role of tumor necrosis factor alpha.
    European journal of immunology, 1995, Volume: 25, Issue:1

    Topics: Antibodies, Monoclonal; Base Sequence; Blotting, Northern; Blotting, Western; Cells, Cultured; Cycloheximide; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Humans; Molecular Sequence Data; NF-kappa B; Receptor-CD3 Complex, Antigen, T-Cell; T-Lymphocytes; Tumor Necrosis Factor-alpha

1995
The regulation of interleukin 5 and interleukin 3 gene expression in human T cells.
    Cytokine, 1994, Volume: 6, Issue:3

    Topics: Base Sequence; Calcimycin; CD4-Positive T-Lymphocytes; Concanavalin A; Cycloheximide; Cyclosporine; DNA Primers; Gene Expression Regulation; Humans; Interleukin-3; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate

1994
How do cells recover from inhibition by cyclosporine?
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cycloheximide; Cyclosporine; Dose-Response Relationship, Drug; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leukocytes; Phosphoprotein Phosphatases

1994
Mechanisms regulating the mRNA levels of interleukin-5 and two other coordinately expressed lymphokines in the murine T lymphoma EL4.23.
    Blood, 1994, Jun-15, Volume: 83, Issue:12

    Topics: Animals; Cycloheximide; Cyclosporine; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-10; Interleukin-2; Interleukin-5; Lymphokines; Lymphoma, T-Cell; Mice; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Posttranscriptional regulation of colony-stimulating factor-1 (CSF-1) and CSF-1 receptor gene expression during inhibition of phorbol-ester-induced monocytic differentiation by dexamethasone and cyclosporin A: potential involvement of a destabilizing prot
    Experimental hematology, 1993, Volume: 21, Issue:10

    Topics: Cell Differentiation; Cycloheximide; Cyclosporine; Dexamethasone; Gene Expression Regulation; Humans; Macrophage Colony-Stimulating Factor; Monocytes; Proto-Oncogene Mas; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1993
Transcriptional and posttranscriptional regulation of the interleukin-4 and interleukin-3 genes in human T cells.
    Blood, 1993, Jan-01, Volume: 81, Issue:1

    Topics: Blotting, Northern; Concanavalin A; Cycloheximide; Cyclosporine; Gene Expression Regulation; Half-Life; Humans; Interleukin-3; Interleukin-4; Kinetics; Nucleic Acid Hybridization; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
Regulation of IFN-gamma and tumor necrosis factor-alpha expression in vivo. Effects of cycloheximide and cyclosporine in normal and lipopolysaccharide-treated mice.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Jan-15, Volume: 150, Issue:2

    Topics: Animals; Cycloheximide; Cyclosporine; Female; Gene Expression Regulation; Histocompatibility Antigens Class II; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; RNA, Messenger; Tumor Necrosis Factor-alpha

1993
Cyclophilin-dependent stimulation of transcription by cyclosporin A.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Amino Acid Isomerases; Carrier Proteins; Cycloheximide; Cyclosporine; Drug Resistance, Microbial; Egtazic Acid; Genes, Fungal; Laccase; Mutagenesis; Neomycin; Oxidoreductases; Peptidylprolyl Isomerase; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Ultraviolet Rays; Xylariales

1993
Characterization of the inhibition of renal translation in the Sprague-Dawley rat following in vivo cyclosporin A.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:1

    Topics: Animals; Cycloheximide; Cyclosporine; Kidney; Leucine; Microsomes; Protein Biosynthesis; Rats; Rats, Sprague-Dawley

1993
Expression of PILOT, a putative transcription factor, requires two signals and is cyclosporin A sensitive in T cells.
    International immunology, 1993, Volume: 5, Issue:1

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Calcimycin; Cell Line; Cycloheximide; Cyclosporine; DNA; Drug Synergism; Early Growth Response Protein 3; Escherichia coli; Gene Expression Regulation; Humans; Molecular Sequence Data; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription, Genetic; Zinc Fingers

1993
Sex hormones and dexamethasone modulate interleukin-5 gene expression in T lymphocytes.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:3

    Topics: Animals; Cell Nucleus; Cycloheximide; Cyclosporine; Dexamethasone; Estradiol; Gene Expression Regulation; Gonadal Steroid Hormones; Hybrid Cells; Interleukin-5; Lymphoma, T-Cell; Mice; Phytohemagglutinins; Progesterone; RNA, Messenger; T-Lymphocytes; Testosterone; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
IL-7 differentially modulates the expression of IFN-gamma and IL-4 in activated human T lymphocytes by transcriptional and post-transcriptional mechanisms.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Feb-15, Volume: 156, Issue:4

    Topics: Cells, Cultured; Cycloheximide; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Humans; Interferon-gamma; Interleukin-4; Interleukin-7; Isoflavones; Lymphocyte Activation; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; RNA, Messenger; Transcription, Genetic; Up-Regulation

1996
Autocrine activation by interferon-gamma of STAT factors following T cell activation.
    European journal of immunology, 1996, Volume: 26, Issue:3

    Topics: Base Sequence; Cycloheximide; Cyclosporine; DNA-Binding Proteins; Humans; Interferon-gamma; Lymphocyte Activation; Lymphoma, T-Cell; Molecular Sequence Data; Monocytes; Signal Transduction; STAT1 Transcription Factor; T-Lymphocytes; Trans-Activators; Tumor Cells, Cultured

1996
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells.
    Nature medicine, 1996, Volume: 2, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Cycloheximide; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Fas Ligand Protein; fas Receptor; Humans; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Methotrexate; Protein Synthesis Inhibitors; Tumor Cells, Cultured

1996
Nuclear appearance of a factor that binds the CD28 response element within the interleukin-2 enhancer correlates with interleukin-2 production.
    The Journal of biological chemistry, 1996, Apr-05, Volume: 271, Issue:14

    Topics: Base Sequence; CD28 Antigens; Consensus Sequence; Cross-Linking Reagents; Cycloheximide; Cyclosporine; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Gene Expression Regulation, Viral; HIV-1; Humans; Interleukin-2; Molecular Weight; NF-kappa B; Nuclear Proteins; T-Lymphocytes; Transcription Factors; Tumor Cells, Cultured

1996
Calcineurin mediates calcium-induced potentiation of adenylyl cyclase activity in dispersed chief cells from guinea pig stomach. Further evidence for cross-talk between signal transduction pathways that regulate pepsinogen secretion.
    The Journal of biological chemistry, 1996, Aug-16, Volume: 271, Issue:33

    Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin-Binding Proteins; Carbachol; Cells, Cultured; Cholecystokinin; Cholera Toxin; Cyclic AMP; Cycloheximide; Cyclosporine; Ethers, Cyclic; Guinea Pigs; Male; Okadaic Acid; Pepsinogens; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Polyenes; Signal Transduction; Sirolimus; Stomach; Tacrolimus

1996
Effects of dexamethasone and cyclosporin A on the accumulation of eosinophils in acute cutaneous inflammation in the guinea-pig.
    British journal of pharmacology, 1996, Volume: 118, Issue:2

    Topics: Animals; Cycloheximide; Cyclosporine; Dermatitis, Atopic; Dexamethasone; Edema; Eosinophils; Guinea Pigs; Immunosuppressive Agents

1996
Lymphotactin gene expression in mast cells following Fc(epsilon) receptor I aggregation: modulation by TGF-beta, IL-4, dexamethasone, and cyclosporin A.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Feb-01, Volume: 158, Issue:3

    Topics: Animals; Cell Line; Chemokine CCL3; Chemokine CCL4; Chemokines, C; Cycloheximide; Cyclosporine; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Interleukin-4; Lymphokines; Macrophage Inflammatory Proteins; Mast Cells; Mice; Mice, Inbred BALB C; Protein Synthesis Inhibitors; Receptor Aggregation; Receptors, IgE; RNA, Messenger; Sialoglycoproteins; Time Factors; Transforming Growth Factor beta

1997
Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.
    Oncogene, 1997, Jan-30, Volume: 14, Issue:4

    Topics: Adenovirus E1B Proteins; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Cell Cycle; Cell Line; Cell Survival; Cycloheximide; Cyclosporine; Dexamethasone; Gamma Rays; Humans; Interleukin-3; Jurkat Cells; Kinetics; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Synergistic induction of CTLA-4 expression by costimulation with TCR plus CD28 signals mediated by increased transcription and messenger ribonucleic acid stability.
    Journal of immunology (Baltimore, Md. : 1950), 1997, May-01, Volume: 158, Issue:9

    Topics: Abatacept; Animals; Antigens, CD; Antigens, Differentiation; CD28 Antigens; Cell Line; CTLA-4 Antigen; Cycloheximide; Cyclosporine; Flow Cytometry; Gene Expression Regulation; Immunoconjugates; Mice; Polyenes; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; RNA, Messenger; Sirolimus; Transcription, Genetic

1997
Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporin A and rapamycin.
    International immunology, 1997, Volume: 9, Issue:7

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cycloheximide; Cyclosporine; Drug Resistance; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-4; Interleukin-5; Leukocytes, Mononuclear; Phytohemagglutinins; Polyenes; Recombinant Proteins; RNA, Messenger; Sirolimus

1997
Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells.
    DNA and cell biology, 1997, Volume: 16, Issue:12

    Topics: Amino Acid Sequence; Base Sequence; Cells, Cultured; Concanavalin A; Cycloheximide; Cyclosporine; DNA-Binding Proteins; G1 Phase; Gene Expression Regulation; Genes, Immediate-Early; Genes, Switch; Humans; Ionomycin; Leukocytes, Mononuclear; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Phorbol Esters; Polymerase Chain Reaction; Resting Phase, Cell Cycle; RNA, Messenger; Sequence Analysis; Transcription Factors

1997
Identification of a Cryphonectria parasitica laccase gene promoter element involved in cycloheximide-inducible, hypovirus-repressible transcriptional activation.
    Gene, 1998, Mar-27, Volume: 210, Issue:1

    Topics: Cell Transformation, Viral; Cycloheximide; Cyclosporine; DNA-Binding Proteins; Fungal Proteins; Fungi; Gene Expression Regulation, Enzymologic; Genes, Fungal; Laccase; Oxidoreductases; Plant Diseases; Promoter Regions, Genetic; Transcriptional Activation; Trees

1998
Two signaling pathways can increase fas expression in human thymocytes.
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Apoptosis; Calcineurin Inhibitors; CD3 Complex; CD4-Positive T-Lymphocytes; Clonal Deletion; Cycloheximide; Cyclosporine; Enzyme Inhibitors; fas Receptor; Humans; Infant; Infant, Newborn; Interferon-gamma; Interleukin-7; Protein Synthesis Inhibitors; Signal Transduction; T-Lymphocytes; Thymus Gland; Up-Regulation

1998
Activation-induced down-regulation of retinoid receptor RXRalpha expression in human T lymphocytes. Role of cell cycle regulation.
    The Journal of biological chemistry, 1998, Aug-14, Volume: 273, Issue:33

    Topics: Base Sequence; CD3 Complex; Cell Cycle; Cloning, Molecular; Cycloheximide; Cyclosporine; Dactinomycin; DNA Primers; Down-Regulation; Gene Expression Regulation; Humans; In Vitro Techniques; Lymphocyte Activation; Molecular Sequence Data; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Messenger; T-Lymphocytes

1998
UVA1 radiation triggers two different final apoptotic pathways.
    The Journal of investigative dermatology, 1999, Volume: 112, Issue:1

    Topics: Annexin A5; Apoptosis; Cell Survival; Cycloheximide; Cyclosporine; DNA Damage; Dose-Response Relationship, Radiation; Humans; Jurkat Cells; Lymphocytes; Mitochondria; Reactive Oxygen Species; Ultraviolet Rays

1999
Inhibition of S6 kinase by rapamycin blocks maturation of Rana dybowskii oocytes.
    General and comparative endocrinology, 1999, Volume: 113, Issue:2

    Topics: Animals; Cycloheximide; Cyclosporine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Immunosuppressive Agents; Oocytes; Precipitin Tests; Progesterone; Protein Kinases; Protein Synthesis Inhibitors; Ranidae; Ribosomal Protein S6 Kinases; Scintillation Counting; Sirolimus; Time Factors

1999
T-cell anergy induced by clonotype-specific antibodies: modulation of an autoreactive human T-cell clone in vitro.
    Immunology, 1999, Volume: 96, Issue:4

    Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Cell Culture Techniques; Cell Survival; Clonal Anergy; Cycloheximide; Cyclosporine; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Receptors, Antigen, T-Cell; T-Lymphocytes; Time Factors; Transcription, Genetic

1999
Cyclosporin A decreases human macrophage interleukin-6 synthesis at post-transcriptional level.
    Mediators of inflammation, 1999, Volume: 8, Issue:4-5

    Topics: Cell Differentiation; Cell Division; Cell Survival; Cycloheximide; Cyclosporine; Dimethyl Sulfoxide; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-6; Macrophages; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; U937 Cells

1999
Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Sep-15, Volume: 165, Issue:6

    Topics: Asthma; Cells, Cultured; Cycloheximide; Cyclosporine; Dexamethasone; Fibrinolysis; Gene Expression Regulation; Humans; Kinetics; Lung; Mast Cells; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Receptors, IgE; RNA, Messenger; Tissue Plasminogen Activator

2000
Eukaryotic translation initiation factor-6 enhances histamine and IL-2 production in mast cells.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Mar-01, Volume: 166, Issue:5

    Topics: Animals; Cell Line; Cycloheximide; Cyclosporine; Dexamethasone; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Histamine; Histamine Release; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-4; Luminescent Proteins; Mast Cells; Mice; Peptide Initiation Factors; Receptors, IgE; RNA, Messenger; Transfection; Up-Regulation

2001
Detection of drug-induced, superoxide-mediated cell damage and its prevention by antioxidants.
    Free radical biology & medicine, 2001, Mar-15, Volume: 30, Issue:6

    Topics: Antioxidants; Benzo(a)pyrene; Cell Division; Cell Survival; Citrinin; Colorimetry; Cycloheximide; Cyclosporine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorenes; Formazans; HeLa Cells; Humans; Lysosomes; Mitochondria; Oxidoreductases; Quercetin; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Toxicity Tests; Xenobiotics

2001
Apoptotic cell death in the hippocampus due to prolonged hypothermic circulatory arrest: comparison of cyclosporine A and cycloheximide on neuron survival.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2001, Volume: 19, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Chromatin; Cryoultramicrotomy; Cycloheximide; Cyclosporine; DNA Fragmentation; Female; Heart Arrest, Induced; Hippocampus; Immunohistochemistry; Neurons; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Swine

2001
Cyclosporine A as a potential neuroprotective agent: a study of prolonged hypothermic circulatory arrest in a chronic porcine model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2001, Volume: 19, Issue:6

    Topics: Animals; Apoptosis; Brain; Cycloheximide; Cyclosporine; Electroencephalography; Female; Heart Arrest, Induced; Intracranial Pressure; Neurons; Protein Synthesis Inhibitors; Random Allocation; Swine

2001
A novel screening for inhibitors of a pleiotropic drug resistant pump, Pdr5, in Saccharomyces cerevisiae.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:7

    Topics: ATP-Binding Cassette Transporters; Ceruletide; Cycloheximide; Cyclosporine; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Fungal; Fluorescent Dyes; Fungal Proteins; Genetic Engineering; Membrane Proteins; Mutation; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Tacrolimus

2001
NF-kappaB is involved in the regulation of CD154 (CD40 ligand) expression in primary human T cells.
    Clinical and experimental immunology, 2001, Volume: 125, Issue:2

    Topics: Adult; Binding Sites; CD40 Ligand; Cells, Cultured; Cycloheximide; Cyclosporine; DNA-Binding Proteins; Genes, Reporter; Humans; I-kappa B Proteins; Jurkat Cells; Lymphocyte Activation; NF-kappa B; NF-KappaB Inhibitor alpha; Oligopeptides; Promoter Regions, Genetic; Protease Inhibitors; Protein Synthesis Inhibitors; RNA, Messenger; T-Lymphocytes; Transcriptional Activation; Transfection

2001
Stimulation of tetrahydrobiopterin synthesis by cyclosporin A in mouse brain microvascular endothelial cells.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:9

    Topics: Animals; Antioxidants; Arginine; Biopterins; Cerebrovascular Circulation; Cycloheximide; Cyclosporine; Endothelium, Vascular; GTP Cyclohydrolase; Immunosuppressive Agents; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Synthesis Inhibitors

2002
Inhibition of interferon-gamma-activated nuclear factor-kappa B by cyclosporin A: A possible mechanism for synergistic induction of apoptosis by interferon-gamma and cyclosporin A in gastric carcinoma cells.
    Biochemical and biophysical research communications, 2003, Jun-13, Volume: 305, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Calcium; Carcinoma; Caspase 3; Caspases; Cycloheximide; Cyclosporine; DNA-Binding Proteins; Drug Synergism; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Models, Biological; NF-kappa B; Phosphoproteins; Protein Synthesis Inhibitors; RNA, Messenger; STAT1 Transcription Factor; Stomach Neoplasms; Tacrolimus; Trans-Activators; Tumor Cells, Cultured

2003
The effects of oxidative stress on mitochondrial transmembrane potential in retinal ganglion cells.
    Antioxidants & redox signaling, 2003, Volume: 5, Issue:5

    Topics: Animals; Animals, Newborn; Bongkrekic Acid; Cells, Cultured; Cycloheximide; Cyclosporine; Dose-Response Relationship, Drug; Hydrogen Peroxide; Intracellular Membranes; Ion Channels; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Phosphines; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; Retinal Ganglion Cells; Sulfhydryl Compounds

2003
Effect of ryanodine receptor mutations on interleukin-6 release and intracellular calcium homeostasis in human myotubes from malignant hyperthermia-susceptible individuals and patients affected by central core disease.
    The Journal of biological chemistry, 2004, Oct-15, Volume: 279, Issue:42

    Topics: Caffeine; Calcium; Cells, Cultured; Cycloheximide; Cyclosporine; Disease Susceptibility; Homeostasis; Humans; Interleukin-6; Kinetics; Malignant Hyperthermia; Muscle Fibers, Skeletal; Myopathy, Central Core; Reference Values; Ryanodine Receptor Calcium Release Channel

2004
Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway.
    Molecular and cellular neurosciences, 2006, Volume: 31, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcineurin; Calcium; Calcium Channel Agonists; Calcium Signaling; Cycloheximide; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Immunosuppressive Agents; Ionophores; Neurons; NFATC Transcription Factors; Oligopeptides; PC12 Cells; Protein Synthesis Inhibitors; Rats; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha

2006
Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF.
    Journal of cellular physiology, 2008, Volume: 217, Issue:2

    Topics: Adenosine Triphosphate; Apoptosis; bcl-2-Associated X Protein; Bongkrekic Acid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Survival; Chloride Channels; Cycloheximide; Cyclosporine; Cytochromes c; Enzyme Inhibitors; Furosemide; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oligomycins; Permeability; Protein Transport; Trifluoperazine; Tumor Necrosis Factor-alpha; Uncoupling Agents

2008
Bax induces cytochrome c release by multiple mechanisms in mitochondria from MCF7 cells.
    Journal of bioenergetics and biomembranes, 2013, Volume: 45, Issue:5

    Topics: Apoptosis; bcl-2-Associated X Protein; Cycloheximide; Cyclosporine; Cytochromes c; Humans; MCF-7 Cells; Mitochondria; Recombinant Proteins; Tumor Necrosis Factor-alpha

2013
Dexamethasone increases αvβ3 integrin expression and affinity through a calcineurin/NFAT pathway.
    Biochimica et biophysica acta, 2013, Volume: 1833, Issue:12

    Topics: Calcineurin; Cell Line; Cycloheximide; Cyclosporine; Dexamethasone; Ethanol; Half-Life; Humans; Integrin alphaVbeta3; Mifepristone; NFATC Transcription Factors; Receptors, Glucocorticoid; RNA Stability; RNA, Messenger; Signal Transduction; Tacrolimus; Trabecular Meshwork

2013
Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Active Transport, Cell Nucleus; Animals; Binding Sites; Cell Line; Cell Nucleus; Cycloheximide; Cyclophilin A; Cyclosporine; Electrophoretic Mobility Shift Assay; Enzyme Activation; Fibroblasts; Gene Expression; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Lactones; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Protein Binding; Signal Transduction; Spiro Compounds; Transcription Factor RelA; Transcription, Genetic; Transcriptional Activation

2014
Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme.
    Cell death & disease, 2017, 05-18, Volume: 8, Issue:5

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Cyclophilins; Cyclosporine; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glioblastoma; Humans; Mice, Nude; Phosphorylation; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA Caps; Signal Transduction; TOR Serine-Threonine Kinases; Unfolded Protein Response; Up-Regulation

2017
Serine/Threonine Phosphatases in LTP: Two B or Not to Be the Protein Synthesis Blocker-Induced Impairment of Early Phase.
    International journal of molecular sciences, 2021, May-04, Volume: 22, Issue:9

    Topics: Animals; Anisomycin; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcineurin; Calcineurin Inhibitors; Cycloheximide; Cyclosporine; Dentate Gyrus; Gene Expression Regulation; Long-Term Potentiation; Male; Microtomy; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase Type I; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Synaptic Potentials; Tissue Culture Techniques

2021