cycloheximide has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (26.76) | 18.2507 |
| 2000's | 45 (63.38) | 29.6817 |
| 2010's | 6 (8.45) | 24.3611 |
| 2020's | 1 (1.41) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Jacobsen, MD; Raff, MC; Weil, M | 1 |
| Aja, TJ; Alnemri, ES; Armstrong, RC; Bai, X; Fritz, LC; Gaur, S; Hoang, KD; Karanewsky, DS; Litwack, G; Tomaselli, KJ | 1 |
| Canzoniero, LM; Choi, DW; Dugan, LL; Farhangrazi, ZS; Gwag, BJ; Sensi, SL; Tian, M; Yeh, CH; Ying, HS; Yu, SP | 1 |
| Azuma, T; Chu, K; Kirschner, MW; Klippel, A; Kothakota, S; Koths, K; Kwiatkowski, DJ; McGarry, TJ; Reinhard, C; Tang, J; Williams, LT | 1 |
| Borner, C; Haas, AL; Monney, L; Olivier, R; Omura, S; Otter, I; Ozer, HL | 1 |
| Neame, SJ; Philpott, KL; Rubin, LL | 1 |
| Brinkmann, U; Keppler-Hafkemeyer, A; Pastan, I | 1 |
| Bushell, M; Clemens, MJ; Morley, SJ | 1 |
| Benito, M; Conejo, R; Lorenzo, M; Navarro, P; Valverde, AM | 1 |
| Chilvers, ER; Farrow, SN; Fujihara, S; Haslett, C; Lawson, MF; Pryde, JG; Rossi, AG; Ward, C | 1 |
| Goswami, J; Sinskey, AJ; Steller, H; Stephanopoulos, GN; Wang, DI | 1 |
| Debatin, KM; Fulda, S; Krammer, PH; Peter, ME; Pietsch, T; Scaffidi, C | 1 |
| Beal, MF; Dichgans, J; Groscurth, P; Heneka, MT; Klockgether, T; Lommatzsch, J; Löschmann, PA; Martinou, JC; Matthews, RT; Schulz, JB; von Coelln, R; Weller, M; Wüllner, U | 1 |
| Engels, IH; Los, M; Rossmann, E; Schulze-Osthoff, K; Wesselborg, S | 1 |
| Grell, M; Haas, E; Scheurich, P; Wajant, H | 1 |
| Alnemri, ES; Chen, M; Itoh, T; Moran, J; Pleasure, D; Reddy, UR | 1 |
| Cohen, GM; Dinsdale, D; Zhuang, J | 1 |
| Canzoniero, LM; Choi, WS; Gwag, BJ; Kim, JE; Lee, EB; O'Malley, KL; Oh, TH; Oh, YJ; Sensi, SL; Sohn, S | 1 |
| Adams, JM; Ofir, R; Zhang, LC | 1 |
| Hong, HN; Kim, DH; Lee, JH; Park, HS | 1 |
| Borner, C; Conus, S; Egger, L; Fellay, I; Häcki, J; Monney, L; Rossé, T | 1 |
| Grell, M; Haas, E; Kreuz, S; Muhlenbeck, F; Scheurich, P; Schubert, G; Schwenzer, R; Smith, C; Wajant, H | 1 |
| Adam-Klages, S; Kabelitz, D; Lüschen, S; Scherer, G; Ussat, S | 1 |
| Cohen, MB; Gewies, A; Rokhlin, OW | 1 |
| Dumont, JE; Galand, P; Lecocq, R; Mosselmans, R; Robaye, B; Suarez-Huerta, N | 1 |
| El Mouedden, M; Laurent, G; Mingeot-Leclercq, MP; Tulkens, PM | 1 |
| Frost, V; Sinclair, AJ | 1 |
| Boise, LH; Cepero, E; Johnson, BW | 1 |
| Boushey, RP; Drucker, DJ; Yusta, B | 1 |
| Amstad, P; Bedner, E; Darzynkiewicz, Z; Smolewski, P | 1 |
| Bennett, MR; Hegyi, L; Proudfoot, D; Shanahan, CM; Skepper, JN; Weissberg, PL | 1 |
| Ahonen, M; Eriksson, JE; Holmstrom, TH; Kahari, VM; Tran, SE | 1 |
| Cao, CX; Dimanche-Boitrel, MT; Nieves-Neira, W; Pommier, Y; Shao, RG; Solary, E | 1 |
| Casas, C; Esquerda, JE; Ribera, J | 1 |
| Lin, HH; Tang, MJ; Wang, YK | 1 |
| Chattopadhaya, S; Sarin, A; Varghese, J | 1 |
| Abé, SI; Fujimoto, K; Yamamoto, T; Yazawa, T | 1 |
| Baba, K; Goto, Y; Masuda, K; Mizuno, T; Ohno, K; Tsujimoto, H | 1 |
| Battistini, L; Bernardi, G; Borsellino, G; Brosnan, CF; Cavaliere, F; Cipriani, B; Knowles, H; Tramonti, D | 1 |
| Mizushima, T; Rokutan, K; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Anel, A; Giraldo, P; Marzo, I; Naval, J; Pérez-Galán, P; Rubio-Félix, D | 1 |
| Kuijpers, TW; Maianski, NA; Mul, FP; Roos, D; van Buul, JD | 1 |
| Jang, JJ; Kim, BC; Kim, HT; Kim, IY; Kim, SJ; Mamura, M; Seong, DH | 1 |
| Billerey, C; Bonnotte, B; Fromentin, A; Garrido, C; Kroemer, G; Larmonier, N; Martin, F; Moutet, M; Parcellier, A; Rébé, C; Solary, E | 1 |
| Gramsbergen, JB; Kristensen, BW; Noer, H; Noraberg, J; Zimmer, J | 1 |
| Choi, J; Li, JH; Madge, LA; Pober, JS | 1 |
| Gauthier, ER; Guérin, PJ | 1 |
| Mousavi, SA; Robson, GD | 1 |
| Borner, C; Egger, L; Häcki, J; Rhême, C; Schneider, J; Tapernoux, M | 1 |
| Alexejun, CN; Levin, LA; Nguyen, SM | 1 |
| Song, J; Yang, Y; Zhao, S | 1 |
| Baizabal, JM; Cárdenas-Aguayo, Mdel C; Covarrubias, L; Salgado, LM; Santa-Olalla, J | 1 |
| Cho, KH; Choi, SM; Kim, BC; Kim, JK; Kim, MK; Lee, SH; Park, MS | 1 |
| Bredholt, T; Costea, DE; Dimba, EA; Fossan, KO; Francis, GW; Gjertsen, BT; Johannessen, AC; Vintermyr, OK | 1 |
| Algeciras-Schimnich, A; Barnhart, BC; Hakem, R; Peter, ME; Pietras, EM; Salmena, L; Sayama, K | 1 |
| Jaruga-Killeen, E; Rayford, W | 1 |
| Koike, T; Suzuki, M | 1 |
| Eley, A; Geary, I; Hakimi, H; Hosseinzadeh, S; Pacey, AA | 1 |
| Brecht, K; Heim, J; Simonen, M | 1 |
| Bremer, E; George, D; Li, H; Monroe, J; Yang, W; Zhang, Y | 1 |
| Duckett, CS; Lewis, J; Novak, R; Phillips, AC; Xia, Y | 1 |
| Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF | 1 |
| Asare, N; Ask, K; Holme, JA; Låg, M; Lagadic-Gossmann, D; Landvik, NE; Rissel, M; Tekpli, X | 1 |
| Miyoshi, N; Murata, Y; Nakamura, Y; Ohshima, H; Okuhira, M; Osawa, T; Watanabe, E | 1 |
| Cancel, LM; Tarbell, JM | 1 |
| Christofferson, DE; Yuan, J | 1 |
| Chen, D; Dong, X; Dou, QP; Guo, H; Huang, H; Li, S; Li, X; Liu, J; Liu, N; Liu, S; Lu, X; Yang, C; Zhang, C; Zhao, C; Zhao, K; Zhou, P | 1 |
| Avalos-Diaz, E; Bollain-y-Goytia, JJ; Daneri-Navarro, A; Herrera-Esparza, R; Ramírez-Sandoval, R; Vazquez-del-Mercado, M | 1 |
| Fujiwara, H; Ichikawa, D; Kitagawa, M; Komatsu, S; Konishi, H; Kosuga, T; Nakashima, S; Okamoto, K; Otsuji, E; Shiozaki, A | 1 |
| Sawai, H | 1 |
71 other study(ies) available for cycloheximide and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death.
Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Apoptosis; Caenorhabditis elegans Proteins; Caspase 1; Caspase 3; Caspases; Cell Line; Cycloheximide; Cysteine Endopeptidases; Extremities; Helminth Proteins; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Oligopeptides; Protease Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Staurosporine | 1996 |
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebellar Cortex; Coumarins; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Enzyme Precursors; Glutamic Acid; Ketones; Mice; Mice, Inbred C57BL; Necrosis; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Potassium; Protein Synthesis Inhibitors | 1997 |
Mediation of neuronal apoptosis by enhancement of outward potassium current.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzopyrans; Calcium; Cerebral Cortex; Cromakalim; Cycloheximide; Cysteine Proteinase Inhibitors; Gadolinium; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channels; Pyrroles; Staurosporine; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine | 1997 |
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis.
Topics: Actins; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cell Line; Cell Size; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeleton; DNA Fragmentation; fas Receptor; Gelsolin; Humans; Mice; Neutrophils; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 7; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cyclin B; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Ligases; Mice; Microtubule-Associated Proteins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases | 1998 |
Blocking cytochrome c activity within intact neurons inhibits apoptosis.
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Biological Transport; Cells, Cultured; Cyclic AMP; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytoplasm; Humans; Intracellular Membranes; Jurkat Cells; Membrane Potentials; Microinjections; Mitochondria; Nerve Growth Factors; Neurons; Neuroprotective Agents; Protein Synthesis Inhibitors; Rats; Superior Cervical Ganglion; Thionucleotides | 1998 |
Role of caspases in immunotoxin-induced apoptosis of cancer cells.
Topics: ADP Ribose Transferases; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Bacterial Toxins; Breast Neoplasms; Caspase 1; Caspase 2; Caspase 3; Caspases; Cycloheximide; Enzyme Activation; Exotoxins; Female; Humans; Immunotoxins; Oligopeptides; Peptide Fragments; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors | 1998 |
Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines.
Topics: Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Caspase Inhibitors; Caspases; Culture Media, Serum-Free; Cycloheximide; Etoposide; Eukaryotic Initiation Factor-4E; fas Receptor; Half-Life; Humans; Jurkat Cells; Lymphoma; Molecular Weight; Neoplasm Proteins; Oligopeptides; Peptide Initiation Factors; Poly(A)-Binding Proteins; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; RNA-Binding Proteins; Sirolimus; Tumor Cells, Cultured | 1998 |
Inhibition of caspases rescues brown adipocytes from apoptosis downregulating BCL-XS and upregulating BCL-2 gene expression.
Topics: Adipocytes; Adipose Tissue, Brown; Amino Acid Chloromethyl Ketones; Apoptosis; bcl-X Protein; Cell Cycle; Cell Line; Culture Media; Cycloheximide; Cysteine Proteinase Inhibitors; Down-Regulation; G1 Phase; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Resting Phase, Cell Cycle; Serum Albumin, Bovine; Up-Regulation | 1999 |
NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gliotoxin; Granulocytes; Humans; Immunosuppressive Agents; In Vitro Techniques; Neutrophils; NF-kappa B; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha | 1999 |
Apoptosis in batch cultures of Chinese hamster ovary cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cell Division; Cell Survival; Cells, Cultured; CHO Cells; Cricetinae; Culture Media, Serum-Free; Cycloheximide; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Humans; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Transfection | 1999 |
Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 8; Caspase 9; Caspases; Cerebellar Neoplasms; Cesium Radioisotopes; Cisplatin; Cycloheximide; Doxorubicin; fas Receptor; Flow Cytometry; Gamma Rays; Glioblastoma; Humans; Immunoglobulin Fab Fragments; Medulloblastoma; Neuroprotective Agents; Tumor Cells, Cultured | 1998 |
Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Brain; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; Corpus Striatum; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Drug Synergism; Genes, bcl-2; Humans; Hypoxia, Brain; In Situ Nick-End Labeling; Male; Malonates; Mice; Mice, Transgenic; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 1998 |
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Caspase 8; Caspase 9; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Daunorubicin; Doxorubicin; Enzyme Activation; Etoposide; Fas Ligand Protein; fas Receptor; HeLa Cells; Humans; Jurkat Cells; Membrane Glycoproteins; Mitomycin; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tumor Cells, Cultured | 1999 |
Continuous autotropic signaling by membrane-expressed tumor necrosis factor.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspases; Cycloheximide; Genes, Reporter; HeLa Cells; Humans; Interferon-gamma; Interleukin-6; Membrane Proteins; Mitogen-Activated Protein Kinases; Mutation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Receptors, Tumor Necrosis Factor; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bucladesine; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Colforsin; Coumarins; Cyclic AMP; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Gene Expression Regulation, Enzymologic; Neurons; Oligopeptides; Potassium; Protein Synthesis Inhibitors; Rats; Transcription, Genetic | 1999 |
Redistribution of cytochrome c precedes the caspase-dependent formation of ultracondensed mitochondria, with a reduced inner membrane potential, in apoptotic monocytes.
Topics: Actins; Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytoskeleton; Etoposide; Flow Cytometry; Golgi Apparatus; Humans; Immunohistochemistry; Membrane Potentials; Mitochondria; Monocytes; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 1999 |
Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Chloromethyl Ketones; Animals; bcl-2-Associated X Protein; Calcium; Caspases; Cell Death; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dopamine; Dopamine Agents; Emetine; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Mesencephalon; Mice; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 1999 |
Interference with gene expression induces rapid apoptosis in p53-null T lymphoma cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cycloheximide; Dactinomycin; Enzyme Activation; Gene Expression Regulation, Neoplastic; JNK Mitogen-Activated Protein Kinases; Lymphoma, T-Cell; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53 | 1999 |
Okadaic acid induces cycloheximide and caspase sensitive apoptosis in immature neurons.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carrier Proteins; Caspase Inhibitors; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Hippocampus; Microfilament Proteins; Neurons; Okadaic Acid; Phosphatidylserines; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anti-Bacterial Agents; Apoptosis; B-Lymphocytes; Biological Transport; Brefeldin A; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Nucleus; Coumarins; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Endoplasmic Reticulum; Fibroblasts; Golgi Apparatus; Humans; Mitochondria; Oligopeptides; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Tunicamycin | 2000 |
Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD).
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Carrier Proteins; Caspase 8; Caspase 9; Caspases; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; fas Receptor; Fas-Associated Death Domain Protein; Gene Expression Regulation; HeLa Cells; Humans; Kinetics; NF-kappa B; Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Sequence Deletion; TNF Receptor-Associated Factor 1; Transcriptional Activation | 2000 |
Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Animals; Carrier Proteins; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle; Cell Survival; Cycloheximide; fas Receptor; Fas-Associated Death Domain Protein; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Serine Proteinase Inhibitors; Signal Transduction; Tumor Necrosis Factor-alpha | 2000 |
Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Ceramides; Cycloheximide; fas Receptor; Humans; Male; Prostatic Neoplasms; Sphingomyelins; Tumor Cells, Cultured | 2000 |
Myosin heavy chain degradation during apoptosis in endothelial cells.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Aorta; Apoptosis; Blotting, Western; Cattle; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Electrophoresis, Gel, Two-Dimensional; Endothelium, Vascular; Enzyme Inhibitors; Microscopy, Electron; Molecular Sequence Data; Molecular Weight; Myosin Heavy Chains; Okadaic Acid; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha; Vimentin | 2000 |
Gentamicin-induced apoptosis in renal cell lines and embryonic rat fibroblasts.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Nucleus; Cycloheximide; DNA; Dogs; Drug Synergism; Electrophoresis, Agar Gel; Embryo, Mammalian; Fibroblasts; Gentamicins; In Situ Nick-End Labeling; Kidney Tubules; LLC-PK1 Cells; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Swine; Transfection | 2000 |
p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; B-Lymphocytes; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; Down-Regulation; Etoposide; fas Receptor; Humans; Jurkat Cells; Microtubule-Associated Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proteins; Signal Transduction; T-Lymphocytes; Tumor Suppressor Proteins | 2000 |
Bcl-xL inhibits cytochrome c release but not mitochondrial depolarization during the activation of multiple death pathways by tumor necrosis factor-alpha.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; B-Lymphocytes; bcl-X Protein; Blotting, Western; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cycloheximide; Cytochrome c Group; DNA; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; fas Receptor; Flow Cytometry; Mice; Mitochondria; Models, Biological; Peptide Hydrolases; Phenotype; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Serpins; Signal Transduction; Tumor Necrosis Factor-alpha; Viral Proteins | 2000 |
The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection | 2000 |
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Camptothecin; Caspase Inhibitors; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; Fluorescent Dyes; HL-60 Cells; Humans; In Situ Nick-End Labeling; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha | 2000 |
Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies.
Topics: Amino Acid Chloromethyl Ketones; Anthraquinones; Apoptosis; Calcinosis; Calcium; Calcium Radioisotopes; Cell Division; Cells, Cultured; Coloring Agents; Cycloheximide; Electron Probe Microanalysis; fas Receptor; Humans; Immunoglobulin M; In Situ Nick-End Labeling; Ki-67 Antigen; Muscle, Smooth, Vascular; Protein Synthesis Inhibitors | 2000 |
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Flavonoids; HeLa Cells; Humans; Kinetics; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2001 |
Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carrier Proteins; Colonic Neoplasms; Cycloheximide; DNA Fragmentation; Fas Ligand Protein; fas Receptor; Fas-Associated Death Domain Protein; Genes, p53; HT29 Cells; Humans; Membrane Glycoproteins; Mutation | 2001 |
Antibodies against c-Jun N-terminal peptide cross-react with neo-epitopes emerging after caspase-mediated proteolysis during apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Antibodies; Antibody Specificity; Apoptosis; Caspase Inhibitors; Caspases; Cycloheximide; Enzyme Inhibitors; Epitopes; Humans; Immunohistochemistry; Immunosorbent Techniques; Microscopy, Fluorescence; Neuroblastoma; Peptide Fragments; Proto-Oncogene Proteins c-jun; Serine-tRNA Ligase; Tumor Cells, Cultured | 2001 |
Collagen gel overlay induces two phases of apoptosis in MDCK cells.
Topics: Actinin; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cell Adhesion; Cell Line; Collagen; Crk-Associated Substrate Protein; Cycloheximide; Cysteine Proteinase Inhibitors; Epithelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Kidney; Oligopeptides; Pepstatins; Phenylmethylsulfonyl Fluoride; Phosphoproteins; Protease Inhibitors; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins pp60(c-src); Retinoblastoma-Like Protein p130; Talin; Vinculin | 2001 |
Inhibition of p38 kinase reveals a TNF-alpha-mediated, caspase-dependent, apoptotic death pathway in a human myelomonocyte cell line.
Topics: Active Transport, Cell Nucleus; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 9; Caspase Inhibitors; Caspases; Cell Death; Cell Nucleus; Cycloheximide; Cysteine Proteinase Inhibitors; Cytotoxicity, Immunologic; Drug Combinations; Enzyme Activation; Gene Expression Regulation; Humans; Jurkat Cells; Macrophages; Mice; Mitogen-Activated Protein Kinases; Myeloid Cells; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Tumor Necrosis Factor-alpha; U937 Cells | 2001 |
Caspase activity in newt spermatogonial apoptosis induced by prolactin and cycloheximide.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Nucleus; Cycloheximide; Male; Organ Culture Techniques; Peptide Hydrolases; Prolactin; Protein Synthesis Inhibitors; Salamandridae; Spermatogonia; Testis | 2001 |
TNF-alpha-induced cell death in feline immunodeficiency virus-infected cells is mediated by the caspase cascade.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cats; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Drug Interactions; Fibroblasts; Immunodeficiency Virus, Feline; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Transfection; Tumor Necrosis Factor-alpha | 2001 |
Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation.
Topics: Adult; Amino Acid Chloromethyl Ketones; Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Bacterial; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Chemokine CCL4; Chemokine CCL5; Curcumin; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Electrophoresis, Agar Gel; Electrophoresis, Gel, Pulsed-Field; Enzyme Activation; Flow Cytometry; Hemiterpenes; Humans; In Situ Nick-End Labeling; Interleukin-15; Interleukin-2; Lymphocyte Activation; Macrophage Inflammatory Proteins; Molecular Weight; NF-kappa B; Organophosphorus Compounds; Phosphorylation; Protein Synthesis Inhibitors; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2001 |
NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gastric Mucosa; Glucosamine; Guinea Pigs; Indomethacin; Male; Microscopy, Fluorescence; Necrosis; Protein Synthesis Inhibitors; Time Factors | 2001 |
Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria.
Topics: Active Transport, Cell Nucleus; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Aphidicolin; Apoptosis; Caspase Inhibitors; Caspases; Cell Division; Cell Survival; Cladribine; Cycloheximide; Cysteine Proteinase Inhibitors; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Serpins; Tumor Cells, Cultured; Viral Proteins | 2001 |
Granulocyte colony-stimulating factor inhibits the mitochondria-dependent activation of caspase-3 in neutrophils.
Topics: Adult; Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase Inhibitors; Caspases; Cycloheximide; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Humans; Membrane Lipids; Microscopy, Confocal; Mitochondria; Neutrophils; Phosphatidylserines; Protein Synthesis Inhibitors; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2 | 2002 |
Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis through cleavage of BAD in TSU-PR1 human cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Caspase 3; Caspases; Cell Division; Cell Membrane; Cell Nucleus; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Estrogen Receptor Modulators; Humans; In Situ Nick-End Labeling; Membrane Potentials; Mitochondria; Phosphorylation; Protein Binding; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Raloxifene Hydrochloride; Retroviridae; Time Factors; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2002 |
An atypical caspase-independent death pathway for an immunogenic cancer cell line.
Topics: Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Apoptosis; Apoptosis Inducing Factor; Caspase Inhibitors; Caspases; Chromatin; Cycloheximide; Cysteine Proteinase Inhibitors; Deoxyribonucleases; Fas Ligand Protein; Flavoproteins; Immunoblotting; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mitochondria; Necrosis; Nucleosomes; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured | 2002 |
Colchicine induces apoptosis in organotypic hippocampal slice cultures.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzimidazoles; Caspase 3; Caspases; Colchicine; Cycloheximide; Dentate Gyrus; Dose-Response Relationship, Drug; Fluorescent Dyes; Immunohistochemistry; Necrosis; Neurons; Neuroprotective Agents; Neurotoxins; Propidium; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors | 2003 |
Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Cathepsin B; Cell Nucleus; Cells, Cultured; Chromones; Cycloheximide; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Interleukin-1; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Retroviridae; Transduction, Genetic; Tumor Necrosis Factor-alpha; Umbilical Veins | 2003 |
Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Azoles; Caspases; Cell Death; Cycloheximide; Cysteine Proteinase Inhibitors; Glutathione Peroxidase; Hybridomas; Isoindoles; Mice; Necrosis; Organoselenium Compounds | 2003 |
Entry into the stationary phase is associated with a rapid loss of viability and an apoptotic-like phenotype in the opportunistic pathogen Aspergillus fumigatus.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Aspergillus fumigatus; Caspase Inhibitors; Caspases; Cell Membrane; Colony Count, Microbial; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Fungal; Electrophoresis, Agar Gel; Microscopy; Phenotype; Phosphatidylserines; Protein Synthesis Inhibitors; Staining and Labeling | 2003 |
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Monoclonal; Apoptosis; Blotting, Western; Brefeldin A; Caspase 3; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Line, Tumor; Cycloheximide; fas Receptor; Fibroblasts; Flow Cytometry; Gene Expression Regulation; HeLa Cells; Humans; Interleukin-3; Mice; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Models, Biological; Phagocytosis; Proto-Oncogene Proteins c-bcl-2; Rats; Serine Endopeptidases; Sulfones; Thapsigargin; Tunicamycin; U937 Cells | 2003 |
Amplification of a reactive oxygen species signal in axotomized retinal ganglion cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Axotomy; Caspases; Cell Physiological Phenomena; Cycloheximide; Ethidium; Hydrogen Peroxide; Microscopy, Fluorescence; Oxidative Stress; Phosphines; Polyethylene Glycols; Rats; Rats, Long-Evans; Reactive Oxygen Species; Retinal Ganglion Cells; Signal Transduction; Superoxide Dismutase; Superoxides; Vitamin K 3 | 2003 |
Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor beta1.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspases; Cell Line; Cell Separation; Cycloheximide; Daunorubicin; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Hepatocytes; Immunoblotting; Mice; Microscopy, Fluorescence; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-delta; Protein Synthesis Inhibitors; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Growth factor deprivation induces an alternative non-apoptotic death mechanism that is inhibited by Bcl2 in cells derived from neural precursor cells.
Topics: Adenine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase Inhibitors; Cell Death; Cell Differentiation; Cell Survival; Chromones; Cycloheximide; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Immunohistochemistry; Intermediate Filament Proteins; Luminescent Proteins; Mesencephalon; Mice; Microscopy, Electron; Morpholines; Nerve Tissue Proteins; Nestin; Neurons; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells; Transformation, Genetic; Tubulin; Vacuoles | 2003 |
5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, Trolox, and Z-VAD-FMK in murine cortical culture.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antimetabolites, Antineoplastic; Antioxidants; Caspase Inhibitors; Cell Culture Techniques; Cell Death; Chromans; Cycloheximide; Cysteine Proteinase Inhibitors; Excitatory Amino Acid Antagonists; Fluorouracil; Mice; Oligodendroglia; Protein Synthesis Inhibitors; Quinoxalines; Receptors, AMPA | 2004 |
Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 1; Caspase 3; Caspase 8; Caspase Inhibitors; Caspases; Catha; Cell Line, Tumor; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Humans; Leukemia; Oligopeptides; Plant Extracts; Propylamines; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 2004 |
CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8.
Topics: Alleles; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Apoptosis; Caspase 8; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Death Domain Receptor Signaling Adaptor Proteins; Drug Resistance, Neoplasm; Enzyme Activation; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mitochondria; Mutation; NF-kappa B; Oligopeptides; Receptors, Tumor Necrosis Factor | 2005 |
TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3.
Topics: Adenoviridae; Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Carrier Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; DNA Fragmentation; Genetic Vectors; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Transduction, Genetic | 2005 |
Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspase 3; Caspase 7; Caspases; Cell Count; Cells, Cultured; Colforsin; Cyclin D1; Cycloheximide; Dihydrotachysterol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Homeostasis; Immunohistochemistry; In Situ Nick-End Labeling; Ionophores; Lactic Acid; Mitochondria; Models, Biological; Necrosis; Nerve Growth Factor; Neurons; Neuroprotective Agents; Peptides; Permeability; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Superior Cervical Ganglion; Time Factors | 2005 |
Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Chlamydia trachomatis; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Ejaculation; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipopolysaccharides; Male; Protein Synthesis Inhibitors; Spermatozoa; Staurosporine; Substrate Specificity | 2005 |
Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; B-Lymphocytes; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspases; Cell Line; Cisplatin; Cycloheximide; Cytochromes c; Doxorubicin; Globins; Green Fluorescent Proteins; HeLa Cells; Hematopoietic Stem Cells; Heme; Humans; Interleukin-3; K562 Cells; Mice; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Staurosporine; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Autophagy; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cycloheximide; Cysteine Proteinase Inhibitors; Cytokines; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Intercellular Signaling Peptides and Proteins; Leupeptins; Male; Microscopy, Electron; Molecular Chaperones; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Synthesis Inhibitors; Signal Transduction | 2006 |
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspase Inhibitors; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Doxycycline; Fibroblasts; Flow Cytometry; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mitochondria; Mutation; Neoplasm Proteins; Tumor Necrosis Factor-alpha; X-Linked Inhibitor of Apoptosis Protein | 2006 |
The extracellular release of HMGB1 during apoptotic cell death.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha | 2006 |
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Caspases; Cell Death; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Culture Media; Cycloheximide; Cytoplasm; Flow Cytometry; Humans; Immunohistochemistry; Microscopy, Electron; Mitogen-Activated Protein Kinases; Phagosomes; Propidium; Protein Synthesis Inhibitors; Pyrenes; Signal Transduction; Vacuoles | 2008 |
ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Cell Membrane; Cell Nucleus; Cell Shape; Cell Survival; Cycloheximide; Deoxyglucose; DNA Fragmentation; DNA, Mitochondrial; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethidium; HeLa Cells; Humans; Isothiocyanates; Mitochondria; Phosphatidylserines; Reactive Oxygen Species | 2008 |
The role of apoptosis in LDL transport through cultured endothelial cell monolayers.
Topics: Amino Acid Chloromethyl Ketones; Animals; Aorta; Apoptosis; Biological Transport; Cattle; Cycloheximide; Endothelial Cells; Humans; Lipoproteins, LDL; Models, Biological; Permeability; Tight Junctions; Tumor Necrosis Factor-alpha; Water | 2010 |
Cyclophilin A release as a biomarker of necrotic cell death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Biomarkers; Cell Line; Cycloheximide; Cyclophilin A; HMGB1 Protein; Humans; Imidazoles; Indoles; Mice; Necrosis; Tumor Necrosis Factor-alpha | 2010 |
Gambogic acid enhances proteasome inhibitor-induced anticancer activity.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Boronic Acids; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Cycloheximide; Cysteine Proteinase Inhibitors; Drug Synergism; Humans; K562 Cells; Leupeptins; Male; Mice; Neoplasms, Experimental; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Transplantation, Homologous; Tumor Burden; Xanthones | 2011 |
Caspase 3 blocking avoids the expression of autoantigens triggered by apoptosis in neonatal Balb/c mice skin.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Autoantigens; Autoimmune Diseases; Biopsy; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Hydrogen Peroxide; In Situ Nick-End Labeling; Mercuric Chloride; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Skin | 2011 |
Tumor necrosis factor-α-induced apoptosis of gastric cancer MKN28 cells: accelerated degradation of the inhibitor of apoptosis family members.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; Caspase 3; Caspase 8; Cell Line, Tumor; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; Leupeptins; NF-kappa B; Oligopeptides; Proteolysis; Quinoxalines; Signal Transduction; Survivin; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein | 2015 |
Induction of Apoptosis in TNF-Treated L929 Cells in the Presence of Necrostatin-1.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cycloheximide; Imidazoles; Indoles; Mice; Necrosis; Poly(ADP-ribose) Polymerases; Tumor Necrosis Factor-alpha | 2016 |