Page last updated: 2024-08-17

cycloheximide and azacitidine

cycloheximide has been researched along with azacitidine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's7 (18.42)18.2507
2000's10 (26.32)29.6817
2010's2 (5.26)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Boutwell, RK; O'Brien, TG; Simsiman, RC1
Cihak, A1
Balas, V; Cihák, A; Cízková, J; Kohout, J; Korbová, L; Malis, F; Marek, J1
Cihák, A; Kohout, J; Korková, L; Reutter, W1
Lyng, RD1
Hirano, T; Kaisho, T; Nakajima, K; Oritani, K1
Hsieh, LL; Weinstein, IB1
Canivet, M; Dianoux, L; Lasneret, J; Lesser, J; Peries, J1
Dürst, M; Rösl, F; zur Hausen, H1
Cavia, E; Webb, TE1
Martin, DW; Owen, NT1
Cerná, J; Cihák, A1
Duff, R; Knight, P; Rapp, F1
Lemke, PA; Nash, CH; Pieper, SW1
Penman, S; Reichman, M1
Cihák, A; Harrap, KR; Veselý, J1
Mann, NS2
Mann, NS; Mauch, MJ1
Coy, K; Gupta, KC; Hershey, H; Levine, RA; Olivelle, S; Taylor, MW; Zawistowich, L1
Hardeland, R; Hoffmann, J1
Coy, K; Hershey, H; Levine, RA; Olivelle, S; Taylor, MW1
Jacquemin-Sablon, A; Segal-Bendirdjian, E1
Gallily, R; Sionov, RV1
Doi, K; Hossain, MM; Nakayama, H; Takashima, A1
Brodeur, GM; Eggert, A; Grotzer, MA; Ikegaki, N; Janss, AJ; Marwaha, S; Phillips, PC; Wiewrodt, BR; Zuzak, TJ1
Fang, D; Setaluri, V; Tsuji, Y1
Choi, HY; Jeon, YK; Kim, CW; Kim, H; Kim, JE; Kim, YA; Kim, YN; Park, SO; Park, SS1
Ain, KB; Li, W; Venkataraman, GM1
Countryman, J; El-Guindy, A; Gradoville, L; Miller, G; Ye, J1
Daigle, D; Gradoville, L; Miller, G; Ye, J1
Capper, D; Gaiser, T; Habel, A; Hartmann, C; Herold-Mende, C; Mueller, W; Siegelin, MD; von Deimling, A1
Beyer, RP; Hallstrand, TS; Kicic, A; Knight, DA; Kobor, MS; Paré, PD; Stevens, PT; Stick, SM; Sutanto, EN; Taplin, C1
Gao, F; Hou, H; Hu, Y; Li, L; Ma, N; Wang, P; Wang, Q; Xie, C; Zhang, H; Zhou, H1

Reviews

2 review(s) available for cycloheximide and azacitidine

ArticleYear
Lower gastric secretion and higher incorporation of orotic acid into liver RNA in rats treated with 5-azacytidine and cycloheximide.
    Neoplasma, 1978, Volume: 25, Issue:3

    Topics: Animals; Azacitidine; Cycloheximide; Gastric Emptying; Gastric Juice; Liver; Male; Orotic Acid; Pepsin A; Rats; RNA; Starvation

1978
Lytic cycle switches of oncogenic human gammaherpesviruses.
    Advances in cancer research, 2007, Volume: 97

    Topics: Azacitidine; Cycloheximide; Cytopathogenic Effect, Viral; DNA Replication; DNA, Viral; Epstein-Barr Virus Infections; Gene Expression Regulation, Viral; Herpesviridae Infections; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Immediate-Early Proteins; Mutation; Oncogenic Viruses; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Trans-Activators; Tumor Virus Infections; Virus Latency

2007

Other Studies

36 other study(ies) available for cycloheximide and azacitidine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Adenosylmethionine Decarboxylase; Animals; Azacitidine; Carboxy-Lyases; Carcinogens; Chick Embryo; Croton Oil; Cycloheximide; Dactinomycin; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Induction; Female; Half-Life; Mice; Ornithine Decarboxylase; Phorbols; RNA; Skin; Time Factors

1975
Character of the stimulatory response of uridine kinase in rat livers to cycloheximide treatment.
    European journal of biochemistry, 1975, Oct-01, Volume: 58, Issue:1

    Topics: Animals; Azacitidine; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Activation; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphotransferases; Puromycin; Rats; Starvation; Uridine Kinase

1975
Inhibitory effect of various cytostatics and cycloheximide on acute experimental pancreatitis in rats.
    Gut, 1977, Volume: 18, Issue:11

    Topics: Acrylates; Acute Disease; Animals; Antimetabolites; Azacitidine; Cycloheximide; Male; Pancreas; Pancreatitis; Rats

1977
Fetal mouse salivary glands and applications for determining teratogenic mechanisms in vitro.
    Toxicology letters, 1992, Volume: 63, Issue:3

    Topics: Animals; Azacitidine; Cyclamates; Cycloheximide; Leucine; Mice; Organ Culture Techniques; Salivary Glands; Teratogens; Thymidine

1992
Retinoic acid inhibits interleukin-6-induced macrophage differentiation and apoptosis in a murine hematopoietic cell line, Y6.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Animals; Apoptosis; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dimethyl Sulfoxide; DNA; Gene Expression; Genes, jun; Genes, myc; Hematopoietic Stem Cells; Interleukin-6; Kinetics; Macrophages; Mice; Mice, Inbred BALB C; RNA; Tetradecanoylphorbol Acetate; Tretinoin

1992
Factors influencing the expression of endogenous retrovirus-like sequences in Rat 6 cells.
    Molecular carcinogenesis, 1990, Volume: 3, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Azacitidine; Blotting, Northern; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Gene Expression Regulation, Viral; Growth Substances; Methylation; Rats; Retroviridae; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
In vitro induction of early mouse embryo intracisternal particles (epsilon particles) in cultured cell lines.
    Biology of the cell, 1990, Volume: 69, Issue:3

    Topics: Animals; Azacitidine; Cell Line; Cell Line, Transformed; Cell Transformation, Viral; Cycloheximide; Dexamethasone; Endoplasmic Reticulum; Fibroblasts; Fluorouracil; Idoxuridine; Inclusion Bodies; Kirsten murine sarcoma virus; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Microscopy, Electron; Mink; Moloney murine sarcoma virus; Puromycin; Rats; Species Specificity; Tumor Cells, Cultured

1990
Selective suppression of human papillomavirus transcription in non-tumorigenic cells by 5-azacytidine.
    The EMBO journal, 1988, Volume: 7, Issue:5

    Topics: Azacitidine; Cycloheximide; DNA, Viral; Humans; Hybrid Cells; Methylation; Papillomaviridae; Transcription, Genetic

1988
Modified induction of ornithine decarboxylase by factors which affect liver regeneration.
    Biochimica et biophysica acta, 1972, Apr-12, Volume: 262, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Age Factors; Animals; Azacitidine; Azaguanine; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Hepatectomy; Hydrocortisone; Liver; Liver Neoplasms; Liver Regeneration; Male; Ornithine; Rats; Solubility

1972
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
    The Journal of biological chemistry, 1972, Sep-10, Volume: 247, Issue:17

    Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium

1972
Stimulatory effect of cycloheximide and related glutarimide antibiotics on liver uridine kinase.
    FEBS letters, 1972, Jun-15, Volume: 23, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Azacitidine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Cycloheximide; Glutarates; Imides; Kinetics; Liver; Liver Regeneration; Male; Phosphotransferases; Rats; Stimulation, Chemical; Uridine

1972
Latency of human measles virus in hamster cells.
    Journal of virology, 1972, Volume: 10, Issue:5

    Topics: Animals; Antigens, Viral; Azacitidine; Cell Fusion; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Fibroblasts; Fluorescent Antibody Technique; Haplorhini; Kidney; Measles virus; Neutralization Tests; Parainfluenza Virus 1, Human; RNA, Viral; Tritium; Uridine; Viral Plaque Assay; Virus Replication

1972
Lytic plaque formation and variation in virus titre among strains of Penicillium chrysogenum.
    Journal of general microbiology, 1973, Volume: 76, Issue:2

    Topics: Anti-Bacterial Agents; Azacitidine; Centrifugation, Density Gradient; Culture Media; Cycloheximide; Ethidium; Hot Temperature; Immunodiffusion; Lactose; Mutation; Penicillin Resistance; Penicillins; Penicillium; Penicillium chrysogenum; Plant Viruses; RNA Viruses; Spectrophotometry; Tritium; Uracil; Virus Replication

1973
The mechanism of inhibition of protein synthesis by 5-azacytidine in HeLa cells.
    Biochimica et biophysica acta, 1973, Oct-12, Volume: 324, Issue:2

    Topics: Azacitidine; Carbon Radioisotopes; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Half-Life; HeLa Cells; Kinetics; Leucine; Neoplasm Proteins; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; RNA, Neoplasm; Tritium; Uridine

1973
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors.
    Biochemical pharmacology, 1974, Mar-15, Volume: 23, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azauridine; Carbon Radioisotopes; Cell-Free System; Cycloheximide; Dactinomycin; Daunorubicin; Diet; Doxorubicin; In Vitro Techniques; Liver; Male; Orotic Acid; Phosphotransferases; Puromycin; Pyrimidines; Rats; Stimulation, Chemical; Thioacetamide; Thymus Gland; Uridine

1974
Effect of intraductal enterokinase, 5-azacytidine and cycloheximide on pancreatic protein content.
    American journal of proctology, gastroenterology & colon & rectal surgery, 1980, Volume: 31, Issue:9

    Topics: Animals; Azacitidine; Bile Ducts; Cycloheximide; Endopeptidases; Enteropeptidase; Male; Pancreas; Proteins; Rats

1980
Inhibitory effect of cycloheximide, somatostatin and 5-azacytidine on acute experimental pancreatitis.
    American journal of proctology, gastroenterology & colon & rectal surgery, 1981, Volume: 32, Issue:7

    Topics: Acute Disease; Animals; Azacitidine; Cycloheximide; Male; Pancreas; Pancreatitis; Rats; Somatostatin

1981
Regulation of de novo purine biosynthesis in Chinese hamster cells.
    The Journal of biological chemistry, 1982, Jan-10, Volume: 257, Issue:1

    Topics: Adenine; Amidophosphoribosyltransferase; Animals; Azacitidine; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cycloheximide; Dactinomycin; Female; Formates; Lung; Ovary; Purines; Ribonucleotides

1982
Different levels of gene realization in the diurnal control of rat liver enzymes.
    Archives internationales de physiologie et de biochimie, 1981, Volume: 89, Issue:4

    Topics: Amanitins; Animals; Argininosuccinate Synthase; ATP Citrate (pro-S)-Lyase; Azacitidine; Circadian Rhythm; Cycloheximide; Deoxyadenosines; Genes; Glutamate Dehydrogenase; Ligases; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; Succinate Dehydrogenase

1981
Reduction in pancreatic protein and amylase content after intraductal 5-azacytidine and cycloheximide.
    American journal of proctology, gastroenterology & colon & rectal surgery, 1981, Volume: 32, Issue:11

    Topics: Amylases; Animals; Azacitidine; Cycloheximide; Injections; Male; Pancreas; Proteins; Rats; Sodium Chloride

1981
Regulation of de novo purine biosynthesis in Chinese hamster cells.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt A

    Topics: Amidophosphoribosyltransferase; Animals; Azacitidine; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Dactinomycin; Female; Kinetics; Lung; Ovary; Pentosyltransferases; Phosphotransferases; Purines; Ribose-Phosphate Pyrophosphokinase

1984
Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process.
    Experimental cell research, 1995, Volume: 218, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Azacitidine; Cell Division; Cell Nucleus; Cisplatin; Clone Cells; Cycloheximide; DNA, Neoplasm; Drug Resistance; Endonucleases; Leukemia L1210; Mice; Microscopy, Confocal; Microscopy, Electron; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1995
Differential H-2 antigen expression in teratocarcinoma-fibroblast hybrids.
    Experimental and clinical immunogenetics, 1995, Volume: 12, Issue:4

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Cell Fusion; Cycloheximide; Fibroblasts; Flow Cytometry; Gene Expression Regulation, Neoplastic; H-2 Antigens; Hybridomas; Interferon-gamma; Mice; Mice, Inbred C57BL; Teratocarcinoma

1995
5-Azacytidine induces toxicity in PC12 cells by apoptosis.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1997, Volume: 49, Issue:3-4

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bucladesine; Cycloheximide; DNA Methylation; L-Lactate Dehydrogenase; Microscopy, Electron, Scanning; Neurons; PC12 Cells; Protein Synthesis Inhibitors; Rats

1997
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.
    Oncogene, 2000, Sep-21, Volume: 19, Issue:40

    Topics: Adult; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Caspase 9; Caspases; Child; Cycloheximide; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Membrane Glycoproteins; Neoplasm Proteins; Neuroectodermal Tumors, Primitive; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF.
    Nucleic acids research, 2002, Jul-15, Volume: 30, Issue:14

    Topics: Acetamides; Azacitidine; Binding Sites; Blotting, Northern; Cells, Cultured; Cycloheximide; Decitabine; DNA-Binding Proteins; Down-Regulation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Hydroxamic Acids; Luciferases; Melanocytes; Membrane Glycoproteins; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Mutation; Oxidoreductases; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Transcription Factors; Tumor Cells, Cultured

2002
Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma.
    Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:7

    Topics: Antibodies, Monoclonal; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cell Proliferation; Cell Survival; Cycloheximide; Death-Associated Protein Kinases; Decitabine; Down-Regulation; Enzyme Activation; Etoposide; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Killer Cells, Natural; Lymphoma, T-Cell, Peripheral; Protein Synthesis Inhibitors

2005
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:3

    Topics: Adenoma; Azacitidine; Butyrates; Cell Line, Tumor; Cycloheximide; Deoxyribonuclease I; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Symporters; Thyroid Neoplasms; Transfection

2007
De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists.
    Journal of virology, 2007, Volume: 81, Issue:17

    Topics: Azacitidine; Blotting, Northern; Cell Line; Cycloheximide; Decitabine; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Herpesvirus 4, Human; Herpesvirus 8, Human; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immediate-Early Proteins; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Trans-Activators; Viral Proteins; Virus Activation

2007
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.
    Acta neuropathologica, 2009, Volume: 117, Issue:4

    Topics: AC133 Antigen; Antigens, CD; Azacitidine; Caspase 3; Caspase 7; Caspase 8; Cell Death; Cycloheximide; Decitabine; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Glioma; Glycoproteins; Humans; Peptides; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Synthesis Inhibitors; RNA, Messenger; Stem Cells; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2009
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium.
    American journal of respiratory and critical care medicine, 2010, May-01, Volume: 181, Issue:9

    Topics: Adolescent; Asthma; Azacitidine; Cells, Cultured; Child; Child, Preschool; Cycloheximide; Dexamethasone; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Matrix; Fibronectins; Homocystine; Humans; Hydroxamic Acids; Hypersensitivity; Microarray Analysis; Respiratory Mucosa; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

2010
5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNF-alpha and cycloheximide via affecting BCL-XL.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:2

    Topics: A549 Cells; Animals; Apoptosis; Azacitidine; bcl-X Protein; Cell Survival; Cycloheximide; DNA Methylation; Gene Expression Regulation; Gene Knockdown Techniques; HeLa Cells; Humans; Mice; NIH 3T3 Cells; RAW 264.7 Cells; Tumor Necrosis Factor-alpha

2018