cycloheximide has been researched along with arachidonic acid in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (33.09) | 18.7374 |
| 1990's | 74 (54.41) | 18.2507 |
| 2000's | 17 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonvini, E; Hoffman, T; Lee, YL; Lizzio, EF; Puri, J; Tripathi, AK | 1 |
| Lew, DB; Malik, KU; Nadel, GL | 1 |
| Hollenberg, MD; Mokashi, S; Severson, DL | 1 |
| Laster, SM; Skinner, T; Voelkel-Johnson, C; Zilli, D | 1 |
| Boulom, K; Fannin, R; Hong, JS; Hudson, P; McMillian, MK; Poisner, AM; Suh, HH | 1 |
| Aizu, E; Kato, R; Yamamoto, S | 1 |
| Elliott, GR; Van de Meent, D; Van Dijk, J | 1 |
| Schatz-Munding, M; Ullrich, V | 1 |
| Etscheid, BG; Ko, PH; Villereal, ML | 1 |
| Holtzman, MJ; Jacobs, SC; Mahoney, M; Pentland, AP | 1 |
| Hollenbach, PW; Laster, SM; Zilli, DL | 1 |
| Davis, BB; Jacob, AK; Thomas, DJ; Zenser, TV | 1 |
| Chang, WC; Huang, JD; Lin, MT; Ning, CC | 1 |
| Jakschik, BA; Xu, L | 1 |
| Ahnfelt-Rønne, I; Kirstein, D; Larsen, CG; Skak-Nielsen, T; Thestrup-Pedersen, K; Thomsen, HK; Thomsen, MK | 1 |
| Asmis, R; Dennis, EA; Glaser, KB | 1 |
| Ansari, GA; Jackson, CA; Peterson, JW; Reitmeyer, JC | 1 |
| Cameron, GS; Fischer, SM; Lee, ML; Patrick, KE | 1 |
| Berglindh, T; Nygård, G | 1 |
| Berglindh, T; Nygãard, G; Nygãrd, G | 1 |
| Arnold, D; Ditschuneit, H; Preclik, G; Stange, EF | 1 |
| Ramesha, CS; Reid, T; Ringold, GM | 1 |
| Coffee, KA; Cook, JA; Geisel, J; Halushka, PV; Wise, WC | 1 |
| Datta, R; Kufe, DW; Sherman, ML; Weber, BL | 1 |
| Mühl, H; Pfeilschifter, J | 1 |
| Emoto, T; Hattori, Y; Hiraiwa, M; Kasai, K; Kuroda, H; Shimoda, S; Yamazaki, A | 1 |
| Fischer, JE; Hasselgren, PO; James, JH; Zamir, O | 1 |
| Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Ozeki, T; Tamura, T; Tsurufuji, S; Watanabe, M | 1 |
| Gauss, J; Herrmann, F; Lindemann, A; Mertelsmann, R | 1 |
| Boeynaems, JM; Boutherin-Falson, O; Galand, N; Lagneau, C | 1 |
| AbuBakar, S; Albrecht, T; Boldogh, I | 1 |
| Billing, P; DiPersio, JF; Gasson, JC; Williams, R | 1 |
| Olson, DM; Zakar, T | 2 |
| Ewenstein, BM; Pober, JS; Schafer, AI; Zavoico, GB | 1 |
| Davis, BB; Wong, YH; Zenser, TV | 1 |
| Bienkowski, MJ; Gorman, RR; Lin, AH | 1 |
| Chakraborti, S; Gurtner, GH; Michael, JR | 1 |
| Kanayasu, T; Morita, I; Murota, S | 1 |
| Glomset, JA; Goerig, M; Graf, T; Habenicht, AJ; Rothe, DE; Specht, E; Ziegler, R | 1 |
| Carrasco, L; Guinea, R; López-Rivas, A | 1 |
| Blackham, A; Griffiths, RJ; Li, S; Wood, BE | 1 |
| Axelrod, J; Burch, RM | 1 |
| Billardon, C; Bure, J; Errasfa, M; Fradin, A; Junien, JL; Rothhut, B; Russo-Marie, F | 1 |
| Covington, M; Newton, RC | 1 |
| Clark, MA; Crooke, ST; Godfrey, RW; Grillone, LR; Stassen, F | 1 |
| Bailey, JM; Pash, JM | 1 |
| Rothenberg, RJ | 1 |
| McKinley, CJ; Turinsky, J | 1 |
| Ardaillou, R; Baud, L; Perez, J | 1 |
| Fagan, JM; Goldberg, AL | 1 |
| Honda, A; Mori, Y; Morita, I; Murota, S | 1 |
| Dandona, P; Jeremy, JY | 2 |
| Nathan, CF; Tsunawaki, S | 1 |
| De Caterina, R; Weksler, BB | 1 |
| Barchowsky, A; Kent, RS; Whorton, AR | 1 |
| Gerritsen, ME; Gordon, GG; Southren, AL; Weinstein, BI | 1 |
| Espe, U; Fürstenberger, G; Kaszkin, M; Kinzel, V; Marks, F | 1 |
| Betz, M; Günther, J; Hänsch, GM; Rother, KO; Sterzel, B | 1 |
| Bomalaski, JS; Chen, MJ; Clark, MA; Crooke, ST | 1 |
| Dauchy, RT; Sauer, LA | 1 |
| Davis, BB; Thomasson, DL; Zenser, TV | 1 |
| Espe, U; Fürstenberger, G; Kaszkin, M; Kinzel, V | 1 |
| Frasier-Scott, K; Hatzakis, H; Jones, CM; Seong, D; Wu, KK | 1 |
| Bailey, JM; Makheja, AN; Pash, J; Verma, M | 1 |
| Bailey, JM; Hla, T; Muza, B; Salata, K | 1 |
| Beaudry, GA; Daniel, LW; Waite, M | 1 |
| Beaudry, GA; Daniel, LW; King, L; Waite, M | 1 |
| Needleman, P; Whiteley, PJ | 1 |
| Chang, WC; Murota, SI; Nakao, J; Orimo, H | 1 |
| Clark, A; D'Souza, SM; Englis, DJ; Russell, RG | 1 |
| Goldberg, AL; Rodemann, HP | 1 |
| Levine, L | 4 |
| Daly, DC; Riddick, DH | 1 |
| De Groot, PG; Gonsalvez, MS; Pool, GA; Van Aken, WG; Van Mourik, JA; Willems, C | 1 |
| Dewald, B; Fey, MF; Meier, RW; Niklaus, G; Tobler, A | 1 |
| Mameya, S; Sawa, T; Taniyama, K | 1 |
| Goetz, FW; Hsu, SY | 1 |
| Pate, JL; Townson, DH | 2 |
| Bartolini, G; Belletti, B; Orlandi, M; Spisni, E; Tomasi, V | 1 |
| Adamson, GM; Billings, RE; Carlson, TJ | 1 |
| Marceau, F; Petitclerc, E; Poubelle, PE | 1 |
| Battles, AH; Lee, JJ | 1 |
| Buckley, BJ; Whorton, AR | 1 |
| Johnson, MS; Mitchell, R; Thomson, FJ; Wolbers, B | 1 |
| Buttke, TM; Tebbey, PW | 1 |
| Bjerve, KS; Brekke, OL; Espevik, T | 1 |
| Hidi, R; Touqui, L; Vargaftig, BB | 1 |
| Hertelendy, F; Molnár, M; Romero, R | 1 |
| Mitchell, R; Thomson, FJ | 1 |
| de Moragas, JM; Godessart, N; Puig, L; Vila, L | 1 |
| Mitchell, MD; Pollard, JK | 1 |
| Chang, WC; Liu, YW; Ning, CC; Suzuki, H; Yamamoto, S; Yoshimoto, T | 1 |
| Cisar, LA; Mochan, E; Schimmel, R | 1 |
| Buller, RM; Glasgow, WC; Palumbo, GJ | 1 |
| Casey, ML; Korte, K | 1 |
| Chen, DB; Harper, MJ; Hilsenrath, R; Le, SP; Yang, ZM | 1 |
| Hassan, MI; Loesch, K; Nokta, MA; Pollard, RB | 1 |
| Chai, SP; Chen, CC; Chu, KY; Fong, JC; Liu, D; Tu, MS | 1 |
| Miller, CW; Ntambi, JM | 1 |
| Cui, S; Rubin, R; Tewari, M; Wu, Y | 1 |
| Cornejo Maciel, F; Cymeryng, C; Dada, L; Finkielstein, C; Maloberti, P; Mele, PG; Mendez, CF; Neuman, I; Paz, C; Podestá, EJ | 1 |
| Anges, C; Zou, M | 1 |
| Bonazzi, A; Boraschi, D; Cassina, E; Folco, G; Habib, A; Hernandez, A; Lebret, M; Maclouf, J; Sala, A; Viganò, T | 1 |
| Fujio, K; Mori, Y; Nakajima, H; Sato, T | 1 |
| Fertel, RH; Garver, CL; Kniss, DA; Zimmerman, PD | 1 |
| Hilton, M; Schuster-Woldan, N; Wilson, T | 1 |
| Dawood, MY; Huang, JC; Liu, DY; Wu, KK; Yadollahi, S | 1 |
| Allen, PD; Jiang, XR; Kelsey, SM; Lillington, DM; Newland, AC; Wu, YL | 1 |
| Matsuoka, T; Nishizaki, T; Nomura, T; Sumikawa, K | 1 |
| Cornejo Maciel, F; Cymeryng, C; Dada, L; Finkielstein, C; Maloberti, P; Mele, PG; Mendez, CF; Neuman, I; Paz, C; Podestá, EJ; Solano, A | 1 |
| Gabriel, A; Gandhi, CR; Kuddus, RH; Rao, AS; Watkins, WD | 1 |
| Chai, SP; Chen, CC; Fong, JC; Ho, LT; Liu, D | 1 |
| Holland, E; Knox, AJ; Pang, L | 1 |
| Delong, P; Hubbard, CL; Huggins, E; McCall, C; O'Sullivan, MG | 1 |
| Bari, F; Busija, DW; Domoki, F; Louis, TM; Perciaccante, JV; Robins, G; Veltkamp, R | 1 |
| Di Rosa, M; Ialenti, A; Ianaro, A; Rombolà, L; Sala, A; Sautebin, L | 1 |
| Androphy, EJ; Chen, JJ; Hong, Y; Liu, Y | 1 |
| Hsu, YW; Lin, WW | 1 |
| Arm, J; Duan, L; Gan, H; Remold, HG | 1 |
| Boaventura, MF; Curi, R; Pompeia, C | 1 |
| Brenner, RR | 1 |
| Alhava, E; Oksala, A; Oksala, NK; Paavonen, T; Paimela, H | 1 |
| Antony, P; Farooqui, AA; Freysz, L; Horrocks, LA | 1 |
| Lisinicchia, JG; Watts, VJ | 1 |
| Culver, CA; Draper, DW; Harris, VG; Laster, SM | 1 |
| Alberghina, M; Anfuso, CD; Assero, G; Cannavò, G; Lupo, G; Nicotra, A; Pluta, R; Rapisarda, P; Strosznajder, RP | 1 |
| Li, GM; Liang, CL; Wang, ZJ; Yin, M; Yu, CY | 1 |
| Bae, CS; Han, HJ; Jung, HK; Kim, DI; Kim, JC; Kim, KY; Lim, SK; Park, AY; Park, MJ; Park, SH; Yoon, KC | 1 |
| Alonso, S; Alvarez, Y; Fernández, N; Municio, C; San Román, JA; Sánchez Crespo, M | 1 |
| Frattini, A; Granata, F; Loffredo, S; Marone, G; Monaco, G; Petraroli, A; Staiano, RI; Triggiani, M | 1 |
3 review(s) available for cycloheximide and arachidonic acid
| Article | Year |
|---|---|
Effects of tumor promoters on arachidonic acid metabolism by cells in culture.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cell Line; Cycloheximide; Dinoprostone; Growth Substances; Humans; Indomethacin; Lipid Metabolism; Male; Peptide Hydrolases; Phorbols; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate; Time Factors; Vitamin A; Vitamin E | 1982 |
Decidual prolactin production in human gestation.
Topics: Amniotic Fluid; Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Decidua; Endometrium; Extraembryonic Membranes; Female; Gestational Age; Humans; Immunosorbent Techniques; In Vitro Techniques; Menstruation; Pituitary Gland; Pregnancy; Progesterone; Prolactin; Prostaglandins; Trophoblasts | 1982 |
Hormonal modulation of delta6 and delta5 desaturases: case of diabetes.
Topics: Animals; Arachidonic Acid; Cyclic AMP; Cycloheximide; Delta-5 Fatty Acid Desaturase; Diabetes Mellitus, Experimental; Docosahexaenoic Acids; Endoplasmic Reticulum; Fatty Acid Desaturases; Hormones; Humans; Insulin; Linoleoyl-CoA Desaturase; Models, Biological; Models, Chemical; Rats; RNA, Messenger | 2003 |
133 other study(ies) available for cycloheximide and arachidonic acid
| Article | Year |
|---|---|
Differential turnover of enzymes involved in human monocyte eicosanoid metabolism. Selective inhibition of cyclooxygenase product formation by cycloheximide in the absence of effects on 5-lipoxygenase or phospholipase A2.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Leukotriene B4; Monocytes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Thromboxane A2 | 1992 |
Prostaglandin E2 synthesis elicited by adrenergic stimuli in guinea pig trachea is mediated primarily via activation of beta 2 adrenergic receptors.
Topics: Albuterol; Animals; Arachidonic Acid; Butoxamine; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Dobutamine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Practolol; Receptors, Adrenergic, beta; Time Factors; Trachea | 1992 |
Synergistic actions of epidermal growth factor-urogastrone and vasopressin in cultured aortic A-10 smooth muscle cells.
Topics: Animals; Annexins; Aorta; Arachidonic Acid; Arginine Vasopressin; Calcium; Calcium-Binding Proteins; Catechols; Cell Line; Cycloheximide; Dactinomycin; Drug Synergism; Epidermal Growth Factor; Muscle, Smooth, Vascular; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Time Factors; Tyrphostins | 1992 |
The adenovirus E3 region 14.7 kDa protein, heat and sodium arsenite inhibit the TNF-induced release of arachidonic acid.
Topics: Adenovirus E3 Proteins; Animals; Arachidonic Acid; Arsenic; Arsenites; Calcimycin; Cell Line; Cycloheximide; Fibroblasts; Hot Temperature; Kinetics; Mice; Mice, Inbred C3H; Recombinant Proteins; Sodium Compounds; Transfection; Tumor Necrosis Factor-alpha | 1992 |
Prolonged stimulation of bovine adrenal chromaffin cells with arachidonic acid and prostaglandin E2 increases expression of the proenkephalin gene and the secretion of [Met5]-enkephalin.
Topics: Adrenal Medulla; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Chromaffin System; Cycloheximide; Dinoprostone; Enkephalin, Methionine; Enkephalins; Gene Expression; Prodrugs; Protein Biosynthesis; RNA, Messenger | 1992 |
Anthralin, a non-TPA type tumor promoter, synergistically enhances phorbol ester-caused prostaglandin E2 release from primary cultured mouse epidermal cells.
Topics: Animals; Anthralin; Arachidonic Acid; Carcinogens; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Drug Synergism; Epidermis; Mice; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1992 |
Interleukin-1 alpha-stimulated fibroblast eicosanoid synthesis is not mediated by interleukin-6.
Topics: Arachidonic Acid; Cells, Cultured; Cycloheximide; Eicosanoids; Fibroblasts; Humans; Interleukin-1; Interleukin-6 | 1992 |
Priming of human polymorphonuclear leukocytes with granulocyte-macrophage colony-stimulating factor involves protein kinase C rather than enhanced calcium mobilisation.
Topics: Alkaloids; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Cations, Divalent; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of bradykinin receptor level by cholera toxin, pertussis toxin and forskolin in cultured human fibroblasts.
Topics: Arachidonic Acid; Arachidonic Acids; Bradykinin; Cells, Cultured; Cholera Toxin; Colforsin; Cycloheximide; Dactinomycin; Fibroblasts; Humans; Pertussis Toxin; Receptors, Bradykinin; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1991 |
Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brompheniramine; Cells, Cultured; Chromatography, High Pressure Liquid; Cimetidine; Cycloheximide; Dinoprostone; Dose-Response Relationship, Radiation; Eicosanoids; Epidermis; Erythema; Histamine; Histamine Release; Humans; In Vitro Techniques; Keratinocytes; Prostaglandins; Pyrilamine; Radiation Injuries, Experimental; Time Factors; Ultraviolet Rays | 1990 |
Inhibitors of transcription and translation act synergistically with tumor necrosis factor to cause the activation of phospholipase A2.
Topics: Animals; Arachidonic Acid; Cell Line; Cell Survival; Chromatography, Thin Layer; Cycloheximide; Dactinomycin; Dexamethasone; Drug Synergism; Enzyme Activation; Humans; Mice; Phospholipases A; Phospholipases A2; Protein Biosynthesis; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1992 |
Regulation of prostaglandin H synthase activity in dog urothelial cells.
Topics: Alkaloids; Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dinoprostone; Dogs; Prostaglandin-Endoperoxide Synthases; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Aspirin; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cycloheximide; Epidermal Growth Factor; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Microsomes; NADP; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Modulation of mast cell eicosanoid synthesis by attachment.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Adhesion; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Eicosanoids; Enzyme Activation; Gene Expression Regulation; Immunoglobulin E; Leukotrienes; Mast Cells; Mice; Phospholipases; Prostaglandin-Endoperoxide Synthases; Receptors, Fc; Receptors, IgE | 1991 |
Recombinant human interleukin-8 is a potent activator of canine neutrophil aggregation, migration, and leukotriene B4 biosynthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Aggregation; Chemotaxis, Leukocyte; Cycloheximide; Dogs; Humans; Injections, Intradermal; Interleukin-1; Interleukin-8; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Skin | 1991 |
PAF receptor mediated PGE2 production in LPS primed P388D1 macrophage-like cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genistein; Isoflavones; Lipopolysaccharides; Macrophages; Mice; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Cells, Cultured | 1991 |
Protein synthesis is required for cholera toxin-induced stimulation of arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cholera Toxin; Cricetinae; Cricetulus; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Protein Biosynthesis | 1991 |
4 Beta- and 4 alpha-12-O-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dactinomycin; Dinoprostone; Down-Regulation; Epidermis; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Endogenous activation of prostaglandin synthesis in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Fractionation; Cell Membrane; Cells, Cultured; Colon; Cycloheximide; Cytochalasin B; Dinoprostone; In Vitro Techniques; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Tetradecanoylphorbol Acetate | 1991 |
Effects of protein synthesis inhibition on PGE2 production in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Colon; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Emetine; Intestinal Mucosa; Male; Organ Culture Techniques; Puromycin; Rabbits; Tritium | 1991 |
In vitro effects of arachidonic acid on the prostaglandin synthesizing system in gastric mucosa.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Chloride; Cycloheximide; Edetic Acid; Gastric Mucosa; Hydrogen Peroxide; Male; Organ Culture Techniques; Prostaglandins; Rabbits; Radioimmunoassay; Tetracaine; Tissue Extracts | 1991 |
Resistance to killing by tumor necrosis factor in an adipocyte cell line caused by a defect in arachidonic acid biosynthesis.
Topics: Adipose Tissue; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Cell Survival; Cycloheximide; Drug Resistance; Fatty Acid Desaturases; Fatty Acids; Kinetics; Linoleoyl-CoA Desaturase; Phospholipids; Tumor Necrosis Factor-alpha | 1991 |
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Camptothecin; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Enterotoxins; Enzyme Activation; Isoquinolines; Macrophages; Male; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Transcriptional and posttranscriptional regulation of macrophage-specific colony stimulating factor gene expression by tumor necrosis factor. Involvement of arachidonic acid metabolites.
Topics: Acetophenones; Arachidonic Acid; Arachidonic Acids; Colony-Stimulating Factors; Cycloheximide; Dinoprostone; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Interleukin 1 and tumor necrosis factor potentiate angiotensin II- and calcium ionophore-stimulated prostaglandin E2 synthesis in rat renal mesangial cells.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Drug Synergism; Glomerular Mesangium; Interleukin-1; Kinetics; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1990 |
Inhibition by protein kinase-C inhibitor and cycloheximide of phorbol ester- and epidermal growth factor-induced arachidonic acid metabolism in cultured porcine thyroid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Isoquinolines; Kinetics; Male; Mice; Piperazines; Protein Kinase C; Sulfonamides; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1990 |
Prostaglandin E2 does not regulate total or myofibrillar protein breakdown in incubated skeletal muscle from normal or septic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dinoprostone; In Vitro Techniques; Indomethacin; Male; Methylhistidines; Muscle Proteins; Rats; Rats, Inbred Strains; Sepsis; Tyrosine | 1990 |
Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Kinetics; Macrophages; Peritoneal Cavity; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Cytokine-stimulation of prostaglandin synthesis from endogenous and exogenous arachidonic acids in polymorphonuclear leukocytes involving activation and new synthesis of cyclooxygenase.
Topics: Arachidonic Acid; Arachidonic Acids; Cycloheximide; Cytokines; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Recombinant Proteins | 1990 |
Enhancement of the endothelial production of prostacyclin by inhibitors of protein synthesis.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cattle; Cell Survival; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Epoprostenol; Half-Life; Protein Biosynthesis; Puromycin; Radioimmunoassay | 1990 |
Human cytomegalovirus. Stimulation of [3H] release from [3H]-arachidonic acid prelabelled cells.
Topics: Antigens, Viral; Arachidonic Acid; Arachidonic Acids; Cell Division; Cell Membrane; Cells, Cultured; Cycloheximide; Cytomegalovirus; Deoxyadenosines; Fibroblasts; Gene Expression; Humans; Immunologic Techniques; Tetradecanoylphorbol Acetate; Tritium; Ultraviolet Rays; Virion | 1990 |
Human granulocyte-macrophage colony-stimulating factor and other cytokines prime human neutrophils for enhanced arachidonic acid release and leukotriene B4 synthesis.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Chemotactic Factors; Colony-Stimulating Factors; Cycloheximide; Dose-Response Relationship, Drug; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Indomethacin; Interleukin-8; Leukotriene B4; Masoprocol; Neutrophils; Pertussis Toxin; Radioimmunoassay; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1988 |
Stimulation of human amnion prostaglandin E2 production by activators of protein kinase-C.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Female; Humans; Pregnancy; Protein Biosynthesis; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate | 1988 |
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis.
Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, Thin Layer; Cycloheximide; Drug Synergism; Endothelium, Vascular; Epoprostenol; Histamine; Humans; Interleukin-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Thrombin; von Willebrand Factor | 1989 |
Regulation of dog urothelial cell arachidonic acid release and prostaglandin E2 synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cell Division; Cells, Cultured; Culture Media; Cycloheximide; Dinoprostone; Dogs; Epithelium; Kinetics; Microscopy, Electron; Tetradecanoylphorbol Acetate; Urinary Bladder | 1989 |
Regulation of prostaglandin H synthase mRNA levels and prostaglandin biosynthesis by platelet-derived growth factor.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Line; Cycloheximide; Dinoprostone; Gene Expression Regulation; Kinetics; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Recombinant Proteins; RNA, Messenger | 1989 |
Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Kinetics; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Pulmonary Artery; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1989 |
A kallikrein induced new peptide stimulating prostacyclin production by vascular endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Carotid Arteries; Cattle; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Kallikreins; Kinetics | 1989 |
Early reversible induction of leukotriene synthesis in chicken myelomonocytic cells transformed by a temperature-sensitive mutant of avian leukemia virus E26.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Avian Leukosis Virus; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chickens; Cycloheximide; Dactinomycin; Kinetics; Leukotriene B4; Macrophages; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Oncogenes; SRS-A | 1989 |
Modification of phospholipase C and phospholipase A2 activities during poliovirus infection.
Topics: Antiviral Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Transformation, Viral; Cycloheximide; Flavonols; HeLa Cells; Humans; Hygromycin B; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phospholipases; Phospholipases A; Phospholipases A2; Poliovirus; Quercetin; Type C Phospholipases | 1989 |
Effects of ciclosporin and protein synthesis inhibitors on cutaneous inflammation in mouse skin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Cyclosporins; Dactinomycin; Dermatitis; Female; Hypersensitivity, Delayed; Mice; Mice, Inbred Strains; Neutrophils; Oxazolone; Peroxidase; Protein Synthesis Inhibitors; Skin; Tetradecanoylphorbol Acetate | 1989 |
Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cycloheximide; Dexamethasone; Dinoprostone; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Mice; Phorbol Esters; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandins E; Receptors, Bradykinin; Receptors, Neurotransmitter | 1987 |
The presence of lipocortin in human embryonic skin fibroblasts and its regulation by anti-inflammatory steroids.
Topics: Abortifacient Agents, Steroidal; Annexins; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Embryo, Mammalian; Estrenes; Female; Fibroblasts; Glycoproteins; Humans; Kinetics; Mifepristone; Pregnancy; Prostaglandins E; Skin; Tritium | 1985 |
The activation of human fibroblast prostaglandin E production by interleukin 1.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Line; Cycloheximide; Dactinomycin; Ethers; Fibroblasts; Humans; Indomethacin; Interleukin-1; Ionomycin; Prostaglandins E; Receptors, Immunologic; Receptors, Interleukin-1; Tetradecanoylphorbol Acetate; Time Factors; Trypsin | 1987 |
Vasopressin induces V1 receptors to activate phosphatidylinositol- and phosphatidylcholine-specific phospholipase C and stimulates the release of arachidonic acid by at least two pathways in the smooth muscle cell line, A-10.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Cell Line; Cycloheximide; Dactinomycin; GTP-Binding Proteins; Lipid Metabolism; Models, Biological; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphatidylcholines; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Time Factors; Type C Phospholipases; Vasopressins; Virulence Factors, Bordetella | 1988 |
Inhibition by corticosteroids of epidermal growth factor-induced recovery of cyclooxygenase after aspirin inactivation.
Topics: Adrenal Cortex Hormones; Animals; Annexins; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cells, Cultured; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Enzyme Activation; Epidermal Growth Factor; Epoprostenol; Glycoproteins; Kinetics; Male; Muscle, Smooth, Vascular; Peptides; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Transforming Growth Factors | 1988 |
Modulation of prostaglandin E2 synthesis in rabbit synoviocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dinoprostone; Durapatite; Female; Hydroxyapatites; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rabbits; Synovial Membrane | 1987 |
Prostaglandin E2 and muscle proteolysis: effect of burn injury and cycloheximide.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Burns; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Male; Muscles; Prostaglandins E; Proteins; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
Dexamethasone and hydrogen peroxide production by mesangial cells during phagocytosis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Estrenes; Hydrogen Peroxide; Kidney Glomerulus; Mifepristone; Phagocytosis; Prostaglandins E; Rats; Zymosan | 1986 |
Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase step.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cycloheximide; Dactinomycin; Emetine; In Vitro Techniques; Male; Muscles; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Puromycin; Rats; RNA, Messenger; Spleen | 1986 |
Appearance of the arachidonic acid metabolic pathway in human promyelocytic leukemia (HL-60) cells during monocytic differentiation: enhancement of thromboxane synthesis by 1 alpha,25-dihydroxyvitamin D-3.
Topics: Arachidonic Acid; Arachidonic Acids; Calcitriol; Carbon Radioisotopes; Cell Differentiation; Cell Line; Cycloheximide; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Methacrylates; Monocytes; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Thromboxane B2; Time Factors; Tretinoin | 1986 |
RU486 antagonizes the inhibitory action of progesterone on prostacyclin and thromboxane A2 synthesis in cultured rat myometrial explants.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Culture Techniques; Cycloheximide; Dactinomycin; Epoprostenol; Estrenes; Female; Mifepristone; Myometrium; Progesterone; Rats; Rats, Inbred Strains; Thromboxane A2 | 1986 |
Inhibition by hydrocortisone of prostacyclin synthesis by rat aorta and its reversal with RU486.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Culture Techniques; Cycloheximide; Dactinomycin; Epinephrine; Epoprostenol; Estrenes; Glucocorticoids; Hydrocortisone; Kinetics; Male; Mifepristone; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains | 1986 |
Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Concanavalin A; Cycloheximide; Deoxyglucose; Emetine; Female; Hydrogen Peroxide; Kinetics; Lectins; Macrophages; Mice; Mice, Inbred ICR; Oxidation-Reduction; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thrombin; Wheat Germ Agglutinins | 1986 |
Modulation of arachidonic acid metabolism in human endothelial cells by glucocorticoids.
Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dexamethasone; Dinoprostone; Endothelium; Epoprostenol; Humans; Hydrocortisone; Kinetics; Prostaglandins; Prostaglandins E; Umbilical Veins | 1986 |
Recovery of porcine aortic endothelial cell prostaglandin synthesis following inhibition by sublethal concentrations of hydrogen peroxide.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Endothelium; Epoprostenol; Hydrogen Peroxide; Kinetics; Prostaglandins; Prostaglandins E; Protein Biosynthesis; Swine | 1987 |
Prostaglandin synthesis and release from cultured human trabecular-meshwork cells and scleral fibroblasts.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Fibroblasts; Humans; Indomethacin; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins E; Prostaglandins H; Sclera; Trabecular Meshwork | 1986 |
Early changes in the arachidonic acid metabolism of HeLa cells in response to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and related compounds.
Topics: Arachidonic Acid; Arachidonic Acids; Carcinogens; Culture Media; Cycloheximide; Dinoprostone; HeLa Cells; Humans; Membrane Lipids; Mitogens; Phorbol Esters; Phospholipids; Prostaglandins E; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
The complement membrane attack complex stimulates the prostanoid production of cultured glomerular epithelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Complement Membrane Attack Complex; Complement System Proteins; Cycloheximide; Dose-Response Relationship, Immunologic; Epithelium; Kidney Glomerulus; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2 | 1988 |
Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Cell Line; Cell Membrane Permeability; Cycloheximide; Dactinomycin; Endothelium; Enzyme Activation; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Pertussis Toxin; Phospholipases; Phospholipases A; Phospholipases A2; Protein Biosynthesis; Proteins; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1988 |
Identification of linoleic and arachidonic acids as the factors in hyperlipemic blood that increase [3H]thymidine incorporation in hepatoma 7288CTC perfused in situ.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; DNA Replication; Hyperlipidemias; Linoleic Acid; Linoleic Acids; Liver Neoplasms, Experimental; Male; Perfusion; Rats; Rats, Inbred BUF; Rats, Inbred Lew; Thymidine; Tritium | 1988 |
Characteristics of bradykinin and TPA increases in the PGE2 levels of human urothelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cells, Cultured; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; In Vitro Techniques; Prostaglandins E; Tetradecanoylphorbol Acetate; Ureter | 1988 |
Dual effect of the phorbol ester TPA on arachidonic acid release from HeLa cells.
Topics: Arachidonic Acid; Arachidonic Acids; Cycloheximide; HeLa Cells; Humans; Kinetics; Phospholipids; Tetradecanoylphorbol Acetate | 1988 |
The action of epidermal growth factor on human amnion prostaglandin E2 output.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Humans; L-Lactate Dehydrogenase; Lysine; Platelet-Derived Growth Factor; Pregnancy; Pregnancy Proteins | 1988 |
Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.
Topics: 6-Ketoprostaglandin F1 alpha; Alanine; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Chromatography, High Pressure Liquid; Cycloheximide; Cysteine; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Humans; Interleukin-2; Molecular Weight; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Serine; Structure-Activity Relationship; Tissue Plasminogen Activator; von Willebrand Factor | 1988 |
Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells.
Topics: Adrenal Cortex Hormones; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cortisone; Cycloheximide; Dactinomycin; Dexamethasone; DNA Probes; Drug Synergism; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains; RNA, Messenger; Transforming Growth Factors | 1988 |
Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: regulation by epidermal growth factor.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood; Cycloheximide; Cytochrome P-450 Enzyme System; Epidermal Growth Factor; Epoprostenol; Intramolecular Oxidoreductases; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Regulation of arachidonic acid metabolism in Madin-Darby canine kidney cells: stimulation of synthesis of the cyclooxygenase system by 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dogs; Enzyme Induction; Kidney; Kinetics; Phorbols; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1985 |
Regulation of arachidonic acid metabolism in Madin-Darby canine kidney cells. Comparison of A23187 and 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cycloheximide; Dinoprostone; Dogs; Kidney; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate | 1984 |
Mechanism of enhanced fibroblast arachidonic acid metabolism by mononuclear cell factor.
Topics: Arachidonic Acid; Arachidonic Acids; Bradykinin; Cycloheximide; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Humans; Kinetics; Microsomes; Monokines; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Proteins | 1984 |
Stimulation of prostaglandin cyclooxygenase and prostacyclin synthetase activities by estradiol in rat aortic smooth muscle cells.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Activation; Epoprostenol; Estradiol; Fatty Acids; Intramolecular Oxidoreductases; Muscle, Smooth, Vascular; Phospholipids; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins H; Rats; Stimulation, Chemical | 1980 |
Stimulation of production of prostaglandin E in gingival cells exposed to products of human blood mononuclear cells.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Line; Cycloheximide; Gingiva; Gingivitis; Humans; Monocytes; Prostaglandins E | 1981 |
Arachidonic acid, prostaglandin E2 and F2 alpha influence rates of protein turnover in skeletal and cardiac muscle.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cycloheximide; Diaphragm; Dinoprost; Dinoprostone; Indomethacin; Kinetics; Meclofenamic Acid; Muscle, Smooth; Muscles; Myocardium; Organ Specificity; Prostaglandins E; Prostaglandins F; Proteins; Rats | 1982 |
Arachidonate metabolism in cultured human vascular endothelial cells. Evidence for two prostaglandin synthetic pathways sensitive to acetylsalicylic acid.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cells, Cultured; Cycloheximide; Endothelium; Female; Humans; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Umbilical Veins | 1982 |
Inhibition of the arachidonic acid pathway prevents induction of IL-8 mRNA by phorbol ester and changes the release of IL-8 from HL 60 cells: differential inhibition of induced expression of IL-8, TNF-alpha, IL-1 alpha, and IL-1 beta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Alkaloids; Arachidonic Acid; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gene Expression; HL-60 Cells; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases A; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Arachidonic acid cascade and stimulation of acetylcholine release by human recombinant interleukin-1 beta in guinea pig ileum.
Topics: Acetylcholine; Animals; Arachidonic Acid; Cholinergic Fibers; Cycloheximide; Electric Stimulation; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Interleukin-1; Intestinal Mucosa; Male; Muscle Contraction; Neuromuscular Junction; Neurons; Nitric Oxide; Parasympathetic Nervous System; Protein Synthesis Inhibitors; Recombinant Proteins; Sensitivity and Specificity; Stimulation, Chemical; Substance P | 1995 |
Cellular mechanisms for orthovanadate-, phorbol ester-, and calcium ionophore-stimulated prostaglandin production in brook trout (Salvelinus fontinalis) follicles.
Topics: Animals; Arachidonic Acid; Calcimycin; Cycloheximide; Dactinomycin; Female; Hydroxyeicosatetraenoic Acids; Ovarian Follicle; Prostaglandins; Tetradecanoylphorbol Acetate; Tritium; Trout; Vanadates | 1993 |
Regulation of prostaglandin synthesis by interleukin-1 beta in cultured bovine luteal cells.
Topics: Animals; Arachidonic Acid; Aristolochic Acids; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprost; Female; Interleukin-1; Luteal Cells; p-Methoxy-N-methylphenethylamine; Phenanthrenes; Phospholipases A; Phospholipases A2; Progesterone; Prostaglandins; Recombinant Proteins; Type C Phospholipases | 1994 |
Thromboxane A2 synthase activity in platelet free human monocytes.
Topics: Apoenzymes; Arachidonic Acid; Blood; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Half-Life; Humans; Monocytes; Prostaglandin-Endoperoxide Synthases; Thromboxane B2; Thromboxane-A Synthase | 1994 |
Phospholipase A2 activation in cultured mouse hepatocytes exposed to tumor necrosis factor-alpha.
Topics: Animals; Arachidonic Acid; Cell Survival; Cells, Cultured; Cycloheximide; Eicosanoids; Enzyme Activation; Humans; Liver; Male; Mice; Phospholipases A; Phospholipases A2; Protein Synthesis Inhibitors; Recombinant Proteins; Terpenes; Tumor Necrosis Factor-alpha | 1994 |
Epidermal growth factor-induced rapid relaxation of the isolated rabbit mesenteric artery.
Topics: Animals; Arachidonic Acid; Cycloheximide; Epidermal Growth Factor; Female; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Rabbits; Vasodilation | 1994 |
Lead toxicity via arachidonate signal transduction to growth responses in the splenic macrophage.
Topics: Animals; Arachidonic Acid; Buthionine Sulfoximine; Cycloheximide; Dinoprostone; Lead; Lipopolysaccharides; Macrophages; Methionine Sulfoximine; Mice; Signal Transduction; Spleen | 1994 |
Ca(2+)-independent arachidonic acid release by vascular endothelium requires protein synthesis de novo.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Fluorides; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Biosynthesis; Swine; Tyrosine; Vanadates | 1994 |
Evidence for a role of phospholipase A2 in the mechanism of LHRH priming in rat anterior pituitary tissue.
Topics: Acetophenones; Aminobenzoates; Animals; Arachidonic Acid; Aristolochic Acids; Calcium; Chlorobenzoates; Cinnamates; Cycloheximide; Female; Gonadotropin-Releasing Hormone; In Vitro Techniques; Luteinizing Hormone; ortho-Aminobenzoates; Phenanthrenes; Phenothiazines; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Proestrus; Quinacrine; Rats; Rats, Wistar | 1994 |
Independent arachidonic acid-mediated gene regulatory pathways in lymphocytes.
Topics: Actins; Animals; Arachidonic Acid; Blotting, Northern; Cell Nucleus; Cycloheximide; Ethanol; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lymphoma; Masoprocol; Mice; RNA, Messenger; RNA, Neoplasm; Stearoyl-CoA Desaturase; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Butylated hydroxyanisole inhibits tumor necrosis factor-induced cytotoxicity and arachidonic acid release.
Topics: Animals; Arachidonic Acid; Butylated Hydroxyanisole; Cell Line; Cell Survival; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fibrosarcoma; Indomethacin; Kinetics; Mice; Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitamin E | 1994 |
Increased synthesis and secretion of a 14-kDa phospholipase A2 by guinea pig alveolar macrophages. Dissociation from arachidonic acid liberation and modulation by dexamethasone.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Guinea Pigs; Hydrogen-Ion Concentration; Leukotriene B4; Macrophages, Alveolar; Male; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Thromboxane B2 | 1993 |
Interleukin-1 and tumor necrosis factor stimulate arachidonic acid release and phospholipid metabolism in human myometrial cells.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Myometrium; Oxytocin; Phospholipids; Pregnancy; Premenopause; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Uterine Contraction | 1993 |
Differential involvement of phospholipase A2 in phorbol ester-induced luteinizing hormone and growth hormone release from rat anterior pituitary tissue.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminobenzoates; Animals; Arachidonic Acid; Aristolochic Acids; Chlorobenzoates; Cinnamates; Cyclohexanones; Cycloheximide; Enzyme Activation; Female; Growth Hormone; Indoles; Ionomycin; Isoquinolines; Luteinizing Hormone; Melitten; ortho-Aminobenzoates; Phenanthrenes; Phenothiazines; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Piperazines; Pituitary Gland, Anterior; Proestrus; Protein Kinase C; Quinacrine; Rats; Rats, Wistar; Signal Transduction; Staurosporine | 1993 |
Interleukin-1 increases 15-hydroxyeicosatetraenoic acid production in human dermal fibroblasts.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Eicosanoids; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Time Factors | 1994 |
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Induction of arachidonate 12-lipoxygenase mRNA by epidermal growth factor in A431 cells.
Topics: Antibodies, Monoclonal; Antibody Specificity; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Blotting, Northern; Cycloheximide; DNA Probes; Epidermal Growth Factor; Humans; Immunosorbent Techniques; Linoleic Acid; Linoleic Acids; Microsomes; RNA, Messenger; Substrate Specificity; Tumor Cells, Cultured | 1993 |
Interleukin-1 selectively potentiates bradykinin-stimulated arachidonic acid release from human synovial fibroblasts.
Topics: Arachidonic Acid; Bradykinin; Calcium; Cells, Cultured; Cyclohexanones; Cycloheximide; Cytosol; Dactinomycin; Drug Synergism; Fibroblasts; Humans; Interleukin-1; Kinetics; Protein Kinase C; Stearic Acids; Synovial Membrane; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 1993 |
Poxvirus-induced alteration of arachidonate metabolism.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Cells, Cultured; Chick Embryo; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Cowpox; Cycloheximide; HeLa Cells; Herpes Simplex; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Peptides; Prostaglandin-Endoperoxide Synthases; Respirovirus; Spectrophotometry, Ultraviolet; Time Factors; Viral Proteins | 1993 |
Vanadate, epidermal growth factor and prostaglandin E2 production in human amnion cells.
Topics: Amnion; Animals; Arachidonic Acid; Cells, Cultured; Culture Media; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Female; Humans; Mice; Pregnancy; Radioimmunoassay; Vanadates | 1993 |
Stimulation of prostaglandin (PG) F2 alpha and PGE2 release by tumour necrosis factor-alpha and interleukin-1 alpha in cultured human luteal phase endometrial cells.
Topics: Arachidonic Acid; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Epithelium; Female; Humans; Interleukin-1; Kinetics; Luteal Phase; Stromal Cells; Tumor Necrosis Factor-alpha | 1995 |
Human cytomegalovirus-induced immunosuppression. Relationship to tumor necrosis factor-dependent release of arachidonic acid and prostaglandin E2 in human monocytes.
Topics: Antibodies, Monoclonal; Arachidonic Acid; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytomegalovirus; Dinoprostone; Humans; Immune Tolerance; Indomethacin; Interleukin-2; Kinetics; Lymphocyte Activation; Monocytes; T-Lymphocytes; Time Factors; Tumor Necrosis Factor-alpha | 1996 |
Arachidonic acid stimulates the intrinsic activity of ubiquitous glucose transporter (GLUT1) in 3T3-L1 adipocytes by a protein kinase C-independent mechanism.
Topics: 3T3 Cells; Adipocytes; Animals; Anisomycin; Arachidonic Acid; Cycloheximide; Deoxyglucose; Dose-Response Relationship, Drug; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Methionine; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Protein Kinase C; Protein Synthesis Inhibitors | 1996 |
Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.
Topics: Animals; Arachidonic Acid; Base Sequence; Chloramphenicol O-Acetyltransferase; Clofibrate; Cycloheximide; Fatty Acids, Unsaturated; Gemfibrozil; Gene Expression Regulation, Enzymologic; Liver; Mice; Mice, Inbred BALB C; Microbodies; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stearoyl-CoA Desaturase; Transcription Factors; Transcription, Genetic | 1996 |
Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death.
Topics: 3T3 Cells; Animals; Apoptosis; Arachidonic Acid; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Protein Synthesis Inhibitors; Receptor, IGF Type 1; Signal Transduction; Tumor Necrosis Factor-alpha | 1996 |
Mechanism of action of TNF-alpha-stimulated prostaglandin production in cultured bovine luteal cells.
Topics: Animals; Arachidonic Acid; Aristolochic Acids; Cattle; Cell Division; Cell Survival; Cells, Cultured; Corpus Luteum; Cycloheximide; Dactinomycin; Dinoprost; Enzyme Inhibitors; Female; Phenanthrenes; Phospholipases A; Phospholipases A2; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1996 |
Cytosolic and mitochondrial proteins as possible targets of cycloheximide effect on adrenal steroidogenesis.
Topics: Animals; Arachidonic Acid; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Cytosol; Mitochondria; Progesterone; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Wistar; Steroids; Zona Fasciculata | 1996 |
Cell-cell interaction between platelets and IL-1 beta-stimulated vascular smooth muscle cells in synthesis of thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Communication; Cells, Cultured; Coculture Techniques; Cycloheximide; Dactinomycin; Humans; Interleukin-1; Muscle, Smooth, Vascular; Phospholipids; Prostaglandin Endoperoxides; Prostaglandin H2; Prostaglandins H; Rats; Recombinant Proteins; Thrombin; Thromboxane A2 | 1997 |
Cyclooxygenase-2 and synthesis of PGE2 in human bronchial smooth-muscle cells.
Topics: Arachidonic Acid; Blotting, Western; Bronchi; Cells, Cultured; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Humans; Immunoblotting; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Membrane Proteins; Muscle, Smooth; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptors, Interleukin-1; Sialoglycoproteins | 1997 |
Enhancement of prostaglandin E2 production by epidermal growth factor requires the coordinate activation of cytosolic phospholipase A2 and cyclooxygenase 2 in human squamous carcinoma A431 cells.
Topics: Acetophenones; Arachidonic Acid; Blotting, Northern; Carcinoma, Squamous Cell; Cloning, Molecular; Cycloheximide; Cyclooxygenase 2; Dinoprostone; Dithiothreitol; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Membrane Proteins; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tumor Cells, Cultured | 1997 |
Interleukin-1 receptor antagonist blocks interleukin-1-induced expression of cyclooxygenase-2 in endometrium.
Topics: Arachidonic Acid; Blotting, Northern; Blotting, Western; Cell Line; Cycloheximide; Cyclooxygenase 2; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Epithelial Cells; Epithelium; Female; Gene Expression Regulation, Enzymologic; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Isomerism; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Receptors, Interleukin-1; RNA, Messenger; Sialoglycoproteins; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
RU486 inhibits synthesis of an endogenous inhibitor of cell arachidonate release from choriodecidua tissue.
Topics: Adult; Arachidonic Acid; Blotting, Western; Chorion; Cycloheximide; Dactinomycin; Decidua; Enzyme Inhibitors; Female; Glucocorticoids; Hormone Antagonists; Humans; Mifepristone; Placenta; Pregnancy; Pregnancy Proteins; Progesterone | 1997 |
Interleukin-1 beta induces cyclooxygenase-2 gene expression in cultured endometrial stromal cells.
Topics: Arachidonic Acid; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprost; Endometrium; Female; Gene Expression; Humans; Interleukin-1; Isoenzymes; Kinetics; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; RNA, Messenger; Stromal Cells | 1998 |
1,25-Dihydroxyvitamin D3 protects human leukemic cells from tumor necrosis factor-induced apoptosis via inactivation of cytosolic phospholipase A2.
Topics: Apoptosis; Arachidonic Acid; Biological Transport; Calcitriol; Cell Membrane; Cycloheximide; Cytoplasm; Dactinomycin; Enzyme Induction; Humans; Leukemia; Oligonucleotides, Antisense; Phospholipases A; Phospholipases A2; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Modulation of ACh receptor currents by arachidonic acid.
Topics: Acetylcholine; Animals; Arachidonic Acid; Brain Chemistry; Chick Embryo; Cycloheximide; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Indomethacin; Ion Channel Gating; Isoquinolines; Maleimides; Masoprocol; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Receptors, Nicotinic; Sulfonamides; Torpedo; Xenopus | 1998 |
An adrenocorticotropin-regulated phosphoprotein intermediary in steroid synthesis is similar to an acyl-CoA thioesterase enzyme.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Cycloheximide; Dactinomycin; Dexamethasone; Female; Glucocorticoids; Mitochondrial Proteins; Molecular Sequence Data; Palmitoyl-CoA Hydrolase; Phosphoproteins; Rats; Rats, Wistar; RNA, Messenger; Steroids; Thiolester Hydrolases; Zona Fasciculata | 1998 |
Superoxide-induced changes in endothelin (ET) receptors in hepatic stellate cells.
Topics: Adipocytes; Animals; Arachidonic Acid; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin-1; Liver; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Superoxides; Xanthine Oxidase | 1998 |
Arachidonic acid and protein synthesis inhibitor act synergistically to suppress insulin-stimulated glucose transport in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Arachidonic Acid; Cell Compartmentation; Cycloheximide; Glucose; Glucose Transporter Type 4; Half-Life; Insulin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Protein Synthesis Inhibitors | 1998 |
Role of cyclo-oxygenase-2 induction in interleukin-1beta induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline.
Topics: Adrenergic beta-Agonists; Adult; Arachidonic Acid; Cell Survival; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Female; Glucocorticoids; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Middle Aged; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Sulfonamides; Trachea; Tumor Necrosis Factor-alpha | 1998 |
Bacterial lipopolysaccharide induction of the prostaglandin G/H synthase 2 gene causes thromboxane-dependent pulmonary hypertension in rabbits.
Topics: Animals; Arachidonic Acid; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dactinomycin; Drug Interactions; Enzyme Induction; Female; Hypertension, Pulmonary; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Perfusion; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; Thromboxanes | 1999 |
Cycloheximide rapidly inhibits cortical COX activity and COX-dependent pial arteriolar dilation in piglets.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Cerebral Cortex; Cerebrovascular Circulation; Cycloheximide; Dinoprost; Epoprostenol; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Swine; Vasodilation | 1999 |
Cyclooxygenase-2-dependent generation of 8-epiprostaglandin F2alpha by lipopolysaccharide-activated J774 macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Cell Line; Cycloheximide; Cyclooxygenase 2; Dexamethasone; Dinoprost; Dinoprostone; Glucocorticoids; Isoenzymes; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors | 1999 |
Rb-independent induction of apoptosis by bovine papillomavirus type 1 E7 in response to tumor necrosis factor alpha.
Topics: Animals; Apoptosis; Arachidonic Acid; Blotting, Western; Cell Death; Cell Division; Cell Line; Cell Separation; Coloring Agents; Cycloheximide; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Formazans; Glutathione Transferase; Humans; Leukemia Virus, Murine; Mice; Oncogene Proteins, Viral; Phospholipases A; Plasmids; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Tumor Necrosis Factor-alpha | 2000 |
Cycloheximide-induced cPLA(2) activation is via the MKP-1 down-regulation and ERK activation.
Topics: Animals; Anisomycin; Arachidonic Acid; Blotting, Western; Calcium; Cell Cycle Proteins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Dual Specificity Phosphatase 1; Enzyme Activation; Enzyme Inhibitors; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphoprotein Phosphatases; Protein Biosynthesis; Protein Phosphatase 1; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Thapsigargin; Time Factors; Vanadates | 2000 |
Lactacystin stimulates arachidonic acid metabolism in rat liver cells: effects of cell density on arachidonic acid release, PGI2 production and cyclooxygenase activity.
Topics: Acetylcysteine; Animals; Arachidonic Acid; Cell Count; Cells, Cultured; Contact Inhibition; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Epoprostenol; Hepatocytes; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2000 |
Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra.
Topics: Adjuvants, Immunologic; Antitubercular Agents; Apoptosis; Arachidonic Acid; Cycloheximide; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Macrophages; Mycobacterium tuberculosis; Phospholipases A; Phospholipases A2; Protein Synthesis Inhibitors; Signal Transduction; Tumor Necrosis Factor-alpha | 2001 |
Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Drug Interactions; Glucocorticoids; Indomethacin; Isoenzymes; Liver; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Pyrazoles; Rats; Sulfonamides | 2001 |
Antiapoptotic effect of dipyrone on HL-60, Jurkat and Raji cell lines submitted to UV irradiation, arachidonic acid and cycloheximide treatments.
Topics: Analgesics; Analgesics, Non-Narcotic; Apoptosis; Arachidonic Acid; Aspirin; B-Lymphocytes; Cycloheximide; Cyclooxygenase Inhibitors; Dipyrone; DNA Fragmentation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Jurkat Cells; Leukemia, B-Cell; Neoplasm Proteins; Parasympatholytics; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Radiation-Protective Agents; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2001 |
Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Kinetics; Liver; Prostaglandin D2; Prostaglandins A; Pyrazoles; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 2001 |
Heat shock preconditioning modulates proliferation and apoptosis after superficial injury in isolated guinea pig gastric mucosa via an eicosanoid and protein synthesis-dependent mechanism.
Topics: Animals; Apoptosis; Arachidonic Acid; bcl-2-Associated X Protein; Cell Division; Cycloheximide; Enzyme Inhibitors; Gastric Mucosa; Guinea Pigs; Heat-Shock Response; Hyperthermia, Induced; Immunohistochemistry; In Vitro Techniques; Indomethacin; Ki-67 Antigen; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quercetin; Wound Healing | 2003 |
Ca2+-independent phospholipases A2 and production of arachidonic acid in nuclei of LA-N-1 cell cultures: a specific receptor activation mediated with retinoic acid.
Topics: Antineoplastic Agents; Arachidonic Acid; Cell Nucleus; Cycloheximide; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Humans; Neuroblastoma; Phospholipases A; Phospholipases A2; Protein Synthesis Inhibitors; Receptors, Retinoic Acid; Subcellular Fractions; Time Factors; Tretinoin; Tumor Cells, Cultured | 2003 |
Sensitization of adenylate cyclase by short-term activation of 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Arachidonic Acid; Buspirone; Calcimycin; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Humans; Indoles; Indomethacin; Maleimides; Pertussis Toxin; Phorbol Esters; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Time Factors; Tryptamines | 2003 |
Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A2 in cells rendered sensitive to TNF-induced apoptosis by cycloheximide.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Arachidonic Acid; Calcium; Caspases; Cell Line; Cell Nucleus; Cycloheximide; Cytosol; Enzyme Activation; Hydrolysis; Intracellular Fluid; Mice; Mice, Inbred C3H; Phosphatidylserines; Phospholipases A; Phospholipases A2; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Verapamil | 2004 |
Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes.
Topics: Amyloid beta-Peptides; Animals; Arachidonic Acid; Arachidonic Acids; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cattle; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Group VI Phospholipases A2; Naphthalenes; Oligopeptides; Peptide Fragments; Pericytes; Phospholipases A; Phospholipases A2; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyrones; Retinal Artery; Staurosporine; Subcellular Fractions | 2004 |
Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.
Topics: Animals; Arachidonic Acid; Benzhydryl Compounds; Benzoquinones; Brain Ischemia; Catalase; Cycloheximide; Epoxy Compounds; Glutathione Peroxidase; Hippocampus; Indoles; Indomethacin; Linoleic Acid; Lipoxygenase Inhibitors; Male; Neuroprotective Agents; Oxidative Stress; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2006 |
Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells.
Topics: Amino Acid Transport System X-AG; Arachidonic Acid; Aspartic Acid; Blotting, Western; Bradykinin; Cell Culture Techniques; Cell Line; Cell Membrane; Cycloheximide; Cyclooxygenase 2; Dactinomycin; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Microsomes, Liver; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Time Factors; Transfection | 2008 |
Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin.
Topics: Antigens, CD; Arachidonic Acid; Atorvastatin; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dendritic Cells; Dinoprostone; Gene Expression; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mevalonic Acid; Peptidoglycan; Phospholipases A2, Cytosolic; Pyrroles; Zymosan | 2009 |
Inhibition of secretory phospholipase A2-induced cytokine production in human lung macrophages by budesonide.
Topics: Arachidonic Acid; Budesonide; Cycloheximide; Cytokines; Dactinomycin; Gene Expression; Glucuronidase; Group IA Phospholipases A2; Group X Phospholipases A2; Humans; Interleukin-6; Interleukin-8; Macrophages, Alveolar; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Secretory; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Tumor Necrosis Factor-alpha | 2009 |