cycloheximide and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Maturation-Promoting Factor; Morpholines; Oocytes; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Wortmannin; Xenopus laevis

Topics: 3T3 Cells; Adipocytes; Animals; Chromones; Cycloheximide; Dactinomycin; Down-Regulation; Gene Expression Regulation; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Mice; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Binding; Receptor, Insulin; Up-Regulation

Topics: Carcinoma, Hepatocellular; Cell Movement; Chromones; Cycloheximide; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitin-Protein Ligases

Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin

Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection

Topics: Animals; Anti-Bacterial Agents; Benzamides; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Separation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Doxycycline; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Genes, abl; Imatinib Mesylate; Interleukin-3; Mice; Microtubule-Associated Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Piperazines; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA; S Phase; Signal Transduction; Sirolimus; Time Factors; Transfection; Tumor Suppressor Proteins

Topics: Butadienes; CD36 Antigens; Chromones; Cycloheximide; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoietin; Flavonoids; Gene Expression Regulation; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured

Topics: Animals; Biopterins; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Chromones; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; GTP Cyclohydrolase; Hypoxanthines; Insulin; Mice; Microcirculation; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors

Topics: Animals; Antigens, CD; Cell Adhesion; Cell Line; Cell Movement; Chromones; Cycloheximide; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocyte Growth Factor; Humans; Integrin alpha2; Integrins; Kidney; Kinetics; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Receptors, Collagen; Recombinant Proteins; Tetradecanoylphorbol Acetate

Topics: Animals; Appetite Depressants; Area Under Curve; Biological Transport; Cells, Cultured; Chromones; Cyclobutanes; Cycloheximide; Cytochalasin B; Deoxyglucose; Enzyme Inhibitors; Glucose; Insulin; Insulin Resistance; Morpholines; Muscles; Protein Synthesis Inhibitors; Rats; Time Factors

Topics: 3T3 Cells; Androstadienes; Animals; Blotting, Northern; Cells, Cultured; Chromones; Collagen; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Kinetics; Lung; Mice; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA Stability; RNA, Messenger; Transfection; Wortmannin

Topics: Acetophenones; Adult; Apoptosis; Benzopyrans; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Chromones; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isoenzymes; Morpholines; Neutrophils; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase C-delta; Protein Synthesis Inhibitors; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: 14-3-3 Proteins; Amino Acids; Animals; Carrier Proteins; Cell Extracts; Chromones; Cycloheximide; Enzyme Inhibitors; Epidermal Growth Factor; Glucose; Growth Substances; Intracellular Signaling Peptides and Proteins; Leupeptins; Morpholines; Nerve Growth Factor; PC12 Cells; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Tyrosine 3-Monooxygenase

Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Cycloheximide; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histidine Decarboxylase; Humans; Hypotonic Solutions; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Morpholines; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Repressor Proteins; Response Elements; RNA, Messenger; Sirolimus; Tetradecanoylphorbol Acetate; Transcription Factors

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Butadienes; Carrier Proteins; Cell Line; Chromones; Cricetinae; Cricetulus; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; JNK Mitogen-Activated Protein Kinases; Lung; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction

Topics: Androstadienes; Apoptosis; Blotting, Western; Bromodeoxyuridine; CD40 Antigens; CD40 Ligand; Cell Division; Cell Movement; Cell Survival; Cells, Cultured; Chromones; Cycloheximide; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Inhibitors; Flow Cytometry; Humans; Morpholines; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Signal Transduction; Time Factors; TNF Receptor-Associated Factor 6; Transfection; Ubiquitin-Protein Ligases; Wortmannin

Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Cathepsin B; Cell Nucleus; Cells, Cultured; Chromones; Cycloheximide; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Interleukin-1; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Retroviridae; Transduction, Genetic; Tumor Necrosis Factor-alpha; Umbilical Veins

Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D3; Cyclins; Cycloheximide; DNA Replication; Down-Regulation; Elongation Factor 2 Kinase; Flow Cytometry; G1 Phase; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Jurkat Cells; Morpholines; Organoselenium Compounds; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Phosphorylation; Polyribosomes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; T-Lymphocytes; Transfection

Topics: Apoptosis; CD40 Antigens; Chromones; Cycloheximide; Humans; Ion Channels; Kinetics; Membrane Transport Proteins; Mitochondrial Proteins; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Proteins; Receptors, Antigen, B-Cell; Uncoupling Protein 2

Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate

Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromones; Cycloheximide; Depression, Chemical; Enzyme Inhibitors; Flavonoids; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Sequence Alignment; Signal Transduction

Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin

Topics: Adenocarcinoma; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Chromones; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Fas-Associated Death Domain Protein; Gene Expression; Humans; Immunoblotting; Morpholines; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Up-Regulation

Topics: Adenocarcinoma; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Cycloheximide; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Lung Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction

Topics: Adenine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase Inhibitors; Cell Death; Cell Differentiation; Cell Survival; Chromones; Cycloheximide; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Immunohistochemistry; Intermediate Filament Proteins; Luminescent Proteins; Mesencephalon; Mice; Microscopy, Electron; Morpholines; Nerve Tissue Proteins; Nestin; Neurons; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells; Transformation, Genetic; Tubulin; Vacuoles

Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Chromones; Cyclin E; Cycloheximide; Enzyme Activation; Growth Inhibitors; Imidazoles; Interleukin-2; Interleukin-7; Lymphocyte Activation; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridines; Retinoblastoma Protein; Signal Transduction; T-Lymphocyte Subsets; Time Factors

Topics: Acetyltransferases; Cell Line, Tumor; Chromones; Cycloheximide; Enzyme Stability; Histone Acetyltransferases; Humans; Morpholines; Nuclear Proteins; Peptide Hydrolases; Phosphatidylinositol 3-Kinases; Proteasome Endopeptidase Complex; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Trans-Activators

Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin

Topics: Adenosine; Animals; Brefeldin A; Chromones; Cycloheximide; Dactinomycin; Enzyme Activation; Golgi Apparatus; Intracellular Membranes; Morpholines; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nucleic Acid Synthesis Inhibitors; PC12 Cells; Phenethylamines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Prosencephalon; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptor, trkB; Receptors, G-Protein-Coupled; Signal Transduction; Transcription, Genetic

Topics: Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspases; Cell Proliferation; Cells, Cultured; Chromones; Cyclin D1; Cycloheximide; DNA; DNA Replication; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Liver; Membrane Glycoproteins; Mitogens; Mitosis; Morpholines; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, Leptin; Repressor Proteins; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Necrosis Factor-alpha

Topics: Cell Hypoxia; Chromones; Cycloheximide; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Kinase Inhibitors; RNA, Messenger; Transcription Factors

Topics: 1-Octanol; Androstadienes; Animals; Bass; Chromones; Cortodoxone; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gap Junctions; Heptanol; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Meiosis; Morpholines; Oocytes; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Wortmannin

Topics: Breast Neoplasms; Cell Line, Tumor; Chromones; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Female; Fibroblast Growth Factor 2; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; MAP Kinase Kinase 1; Morpholines; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factors; Vascular Endothelial Growth Factor A

Topics: Apigenin; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Colorectal Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Humans; Interferon-Stimulated Gene Factor 3; Kaempferols; Ligands; MAP Kinase Kinase Kinases; Morpholines; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Polyphenols; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Quercetin; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Time Factors; Tumor Escape; Tumor Necrosis Factor-alpha

Topics: Apoptosis; Apoptosis Regulatory Proteins; Biomarkers, Tumor; Chromones; Class I Phosphatidylinositol 3-Kinases; Collagen; Cycloheximide; Humans; In Vitro Techniques; Macrophages; Membrane Glycoproteins; Mesothelioma; Models, Biological; Morpholines; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins c-akt; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Spheroids, Cellular; Stromal Cells; TNF-Related Apoptosis-Inducing Ligand; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Androstadienes; Animals; Carps; Cattle; Chorionic Gonadotropin; Chromones; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Insulin; Morpholines; Oocytes; Ovarian Follicle; Somatomedins; Species Specificity; Steroids; Time Factors; Wortmannin

Topics: Apoptosis; Cell Division; Cell Line, Tumor; Cell Survival; Cholera Toxin; Chromones; Cycloheximide; Cycloparaffins; Enzyme Inhibitors; Genes, Reporter; Glucagon-Like Peptide-1 Receptor; Humans; Indomethacin; Kinetics; Mitogen-Activated Protein Kinase 3; Morpholines; Pancreatic Neoplasms; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

Topics: 3T3-L1 Cells; Angiopoietin-Like Protein 4; Angiopoietins; Animals; Blood Proteins; Chromones; Cycloheximide; Dactinomycin; Down-Regulation; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Glucose; Insulin; Mice; Morpholines; Proto-Oncogene Proteins c-akt; RNA, Messenger; Tumor Necrosis Factor-alpha

Topics: Androstadienes; Animals; Bass; Chromones; Cycloheximide; Dactinomycin; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Morpholines; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Sexual Maturation; Steroids; Wortmannin

Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromones; Cycloheximide; Drug Evaluation, Preclinical; Drug Synergism; Galactosyltransferases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Morpholines; Phosphatidylinositol 3-Kinases; Substrate Specificity; Up-Regulation; Wortmannin

Topics: Apoptosis; Cell Line, Tumor; Chromones; Clone Cells; Cycloheximide; DNA, Mitochondrial; Humans; Leukemia, Myeloid; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Cell Line, Tumor; Cell Survival; Chromones; Cycloheximide; Deoxycytidine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gemcitabine; Humans; Mesothelioma; Morpholines; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Signal Transduction; Sirolimus; Spheroids, Cellular; TNF-Related Apoptosis-Inducing Ligand; TOR Serine-Threonine Kinases

Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Chromones; Cycloheximide; Gene Expression; Humans; Iodides; Morpholines; Oncogene Protein v-akt; Paired Box Transcription Factors; PAX8 Transcription Factor; Phosphoinositide-3 Kinase Inhibitors; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Symporters; Thyroid Gland; Thyroid Neoplasms

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin

Topics: Apoptosis; Base Sequence; Cell Hypoxia; Cells, Cultured; Chromatin Immunoprecipitation; Chromones; Cycloheximide; Dermis; Endothelial Cells; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Humans; Immunoblotting; Microscopy, Fluorescence; Molecular Sequence Data; Morpholines; Oxygen; Phosphorylation; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection; Tumor Necrosis Factor-alpha

Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Chromones; Cycloheximide; Dual Specificity Phosphatase 1; Humans; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation

Topics: Antineoplastic Agents; Cell Survival; Chromones; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Fluorouracil; HT29 Cells; Humans; Insulin; Morpholines; Obesity; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Time Factors

Topics: Amides; Aminoquinolines; Cell Line; Chromones; Cycloheximide; Dactinomycin; Female; Humans; Interleukin-6; Lysophospholipids; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Trophoblasts

Topics: Animals; Chromones; Cycloheximide; Enzyme Activation; HEK293 Cells; Humans; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proteolysis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Sirolimus; Substrate Specificity; Tumor Suppressor Protein p53

Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Chromones; Cycloheximide; Enzyme Activation; Leptin; Mice; Morpholines; Phosphatidylinositol 3-Kinase; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Time Factors; Triiodothyronine