Page last updated: 2024-08-18

cyclohexene and mk 6892

cyclohexene has been researched along with mk 6892 in 1 studies

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, TQ; Carballo-Jane, E; Chen, Q; Cheng, K; Colletti, SL; Deng, Q; Ding, FX; Forrest, MJ; Hammond, ML; Holt, TG; Krsmanovic, ML; Luell, S; Raghavan, S; Ren, N; Shen, HC; Taggart, AK; Tata, JR; Tong, X; Wang, J; Waters, MG; Wilsie, LC; Wolff, MS; Wu, KK; Wu, TJ1

Other Studies

1 other study(ies) available for cyclohexene and mk 6892

ArticleYear
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Animals; Area Under Curve; Binding, Competitive; Carboxylic Acids; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Cyclohexenes; Dogs; Drug Discovery; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Humans; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Chemical; Molecular Structure; Oxadiazoles; Rats; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Structure-Activity Relationship; Vasodilation

2010