Page last updated: 2024-08-18

cyclohexanone and curcumin

cyclohexanone has been researched along with curcumin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chandramouli, A; Larsen, L; Nelson, MA; Rosengren, RJ; Somers-Edgar, TJ; Taurin, S1
Diederich, M; Larsen, L; Rosengren, RJ; Schumacher, M; Somers-Edgar, TJ; Taurin, S; Yadav, B1
Gandhy, SU; Kim, K; Larsen, L; Rosengren, RJ; Safe, S1
Israf, DA; Lajis, NH; Lee, YZ; Ming-Tatt, L; Sulaiman, MR; Tham, CL1
Ao, GZ; Cao, Y; Li, HQ; Ma, H; Xu, YY1
Hawkins, BC; Li, Y; Paxton, JW; Revalde, JL; Rosengren, RJ1
Abas, F; Abdul Bahari, MN; Ahmad, S; Lajis, NH; Lam, KW; Leong, SW; Mohd Aluwi, MF; Mohd Faudzi, SM; Rullah, K; Shaari, K; Tham, CL1
Bugde, P; Hawkins, BC; Li, Y; Paxton, JW; Revalde, JL; Rosengren, RJ; Wijeratne, TS1
Alibeiki, F; Jafari, N; Karimi, M; Peeri Dogaheh, H1
Abas, F; Ahmad, S; Lai, KS; Nazarudin, NA; Razali, NA1
Fuji, S; Kato, H; Limtrakul Dejkriengkraikul, P; Mapoung, S; Naiki-Ito, A; Ovatlarnporn, C; Suzuki, S; Takahashi, S; Yodkeeree, S1

Other Studies

11 other study(ies) available for cyclohexanone and curcumin

ArticleYear
Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines.
    Investigational new drugs, 2011, Volume: 29, Issue:1

    Topics: Breast Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Curcumin; Cyclohexanones; Drug Screening Assays, Antitumor; Female; G2 Phase; Heterocyclic Compounds; Humans; Neoplasm Proteins; Receptors, Estrogen; Signal Transduction

2011
Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Curcumin; Cyclohexanones; Female; Heterocyclic Compounds; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; NF-kappa B; Structure-Activity Relationship

2010
Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
    BMC cancer, 2012, Nov-30, Volume: 12

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Curcumin; Cyclin D1; Cyclohexanones; Down-Regulation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; NF-kappa B; Piperidines; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-met; Reactive Oxygen Species; Repressor Proteins; Sp Transcription Factors

2012
Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma.
    Molecules (Basel, Switzerland), 2012, Dec-07, Volume: 17, Issue:12

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Curcumin; Cyclohexanones; Rats; Reference Standards; Spectrophotometry, Ultraviolet

2012
Design, synthesis and molecular docking of α,β-unsaturated cyclohexanone analogous of curcumin as potent EGFR inhibitors with antiproliferative activity.
    Bioorganic & medicinal chemistry, 2013, Jan-15, Volume: 21, Issue:2

    Topics: Antineoplastic Agents; Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclohexanones; Drug Design; ErbB Receptors; Hep G2 Cells; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Structure-Activity Relationship

2013
Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance.
    Biochemical pharmacology, 2015, Feb-01, Volume: 93, Issue:3

    Topics: Animals; ATP-Binding Cassette Transporters; Cell Line, Tumor; Curcumin; Cyclohexanones; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HEK293 Cells; Heterocyclic Compounds; Humans; Insecta; Madin Darby Canine Kidney Cells

2015
Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives.
    Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16

    Topics: Animals; Antioxidants; Benzylidene Compounds; Cell Survival; Curcumin; Cyclohexanones; Humans; Inhibitory Concentration 50; Macrophages; Mice; Microsomes, Liver; Nitric Oxide; Pentanoic Acids; RAW 264.7 Cells; Structure-Activity Relationship

2015
Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells.
    European journal of pharmacology, 2017, May-15, Volume: 803

    Topics: Antineoplastic Agents; Cell Line, Tumor; Curcumin; Cyclohexanones; Deoxycytidine; Drug Interactions; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Pancreatic Neoplasms; Uridine

2017
Potent anti-cancer effects of less polar Curcumin analogues on gastric adenocarcinoma and esophageal squamous cell carcinoma cells.
    Scientific reports, 2017, 05-31, Volume: 7, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclohexanones; Esophageal Squamous Cell Carcinoma; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Stomach Neoplasms

2017
Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-κB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT).
    BMC complementary and alternative medicine, 2018, Jul-16, Volume: 18, Issue:1

    Topics: Anti-Inflammatory Agents; Cell Line; Curcumin; Cyclohexanones; Extracellular Signal-Regulated MAP Kinases; Histamine; Humans; Interleukin-6; Keratinocytes; MAP Kinase Signaling System; NF-kappa B

2018
Cyclohexanone curcumin analogs inhibit the progression of castration-resistant prostate cancer in vitro and in vivo.
    Cancer science, 2019, Volume: 110, Issue:2

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclohexanones; Disease Progression; Drug Resistance, Neoplasm; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; PC-3 Cells; Prostatic Neoplasms, Castration-Resistant; Xenograft Model Antitumor Assays

2019