cyclohexanol has been researched along with lomibuvir in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beigelman, L; Blatt, L; Cai, H; Deval, J; Fan, B; Kao, CC; Ranjith-Kumar, CT; Smith, DB; Soulard, C; Yi, G | 1 |
| Jiao, P; Liu, H; Xue, W; Yao, X | 1 |
| Alves, K; Asmal, M; DeSouza, C; Di Bisceglie, AM; Gane, E; George, S; Jacobson, IM; Kauffman, R; Kieffer, T; Koziel, MJ; Nelson, D; Sulkowski, M; Zhang, EZ | 1 |
| Ardzinski, A; Bartels, DJ; Davis, A; Dorrian, J; Jiang, M; Kieffer, TL; Nelson, M; Nicolas, O; Rao, BG; Rijnbrand, R; Spanks, J; Sullivan, JC; Tigges, A; Zhang, EZ | 1 |
| Douglas, MW; Eltahla, AA; Tay, E; White, PA | 1 |
| Hodges, MR; Ottosen, S; Parsley, TB; Patick, AK; Raney, AK; van der Veer, E; van Doorn, LJ; Yang, L; Zeh, K | 1 |
| Ardzinski, A; Bilimoria, D; Chan, L; Chandupatla, K; Chauret, N; Collier, PN; Court, JJ; Das, SK; Denis, F; Dorsch, W; Green, J; Iyer, G; L'Heureux, L; Lauffer, D; Li, P; Luisi, BS; Mani, N; Nanthakumar, S; Nicolas, O; Poisson, C; Rao, BG; Ronkin, S; Selliah, S; Shawgo, RS; Tang, Q; Waal, ND; Yannopoulos, CG | 1 |
3 trial(s) available for cyclohexanol and lomibuvir
| Article | Year |
|---|---|
VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Cyclohexanols; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiophenes; Treatment Outcome; Viral Nonstructural Proteins; Young Adult | 2014 |
Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cyclohexanols; Drug Resistance, Viral; Genetic Variation; Genotype; Hepacivirus; Hepatitis C; Humans; Molecular Sequence Data; Mutation; Oligopeptides; Phenotype; Replicon; Thiophenes; Viral Nonstructural Proteins; Virus Replication | 2014 |
In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122.
Topics: 5' Untranslated Regions; Antiviral Agents; Carbamates; Cyclohexanols; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Macrocyclic Compounds; MicroRNAs; Molecular Targeted Therapy; Mutation; Oligonucleotides; Oligopeptides; Pyrrolidines; Quinolines; Replicon; Thiazoles; Thiophenes; Valine | 2015 |
4 other study(ies) available for cyclohexanol and lomibuvir
| Article | Year |
|---|---|
Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir.
Topics: Antiviral Agents; Binding Sites; Cell Line, Tumor; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Hepacivirus; Humans; Models, Molecular; Mutation; Pyrones; Replicon; RNA-Dependent RNA Polymerase; RNA, Viral; Templates, Genetic; Thiophenes; Triazoles | 2012 |
Molecular modeling and residue interaction network studies on the mechanism of binding and resistance of the HCV NS5B polymerase mutants to VX-222 and ANA598.
Topics: Antiviral Agents; Benzothiadiazines; Binding Sites; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Protein Binding; Quinolones; Thiophenes; Viral Nonstructural Proteins | 2014 |
Cross-genotypic examination of hepatitis C virus polymerase inhibitors reveals a novel mechanism of action for thumb binders.
Topics: Antiviral Agents; Benzimidazoles; Benzofurans; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Genotype; Hepacivirus; Humans; Purines; Pyridazines; Pyrones; Recombinant Proteins; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Sulfonamides; Thiophenes; Triazoles; Viral Proteins | 2014 |
Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
Topics: Allosteric Regulation; Antiviral Agents; Cyclohexanols; Dose-Response Relationship, Drug; Drug Discovery; Hepacivirus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes; Viral Nonstructural Proteins; Virus Replication | 2016 |