Page last updated: 2024-08-18

cyclohexanol and 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea

cyclohexanol has been researched along with 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Babbs, AJ; Bali, U; Horswill, JG; Jeevaratnam, P; Keily, JF; Reynet, C; Shaaban, S; Wong Kai In, P1
Breen, CM; Cawston, EE; Connor, M; Glass, M; Grimsey, NL; Redmond, WJ1
Farrens, DL; Fay, JF1
Cascio, MG; Denovan-Wright, EM; Janero, DR; Korde, A; Kulkarni, AR; Kulkarni, PM; Laprairie, RB; Makriyannis, A; Pertwee, RG; Thakur, GA; Tichkule, RB; Zhou, H; Zvonok, N1
Farquhar, CE; Gamage, TF; Lefever, TW; Nguyen, T; Thomas, BF; Wiley, JL; Zhang, Y1
Dopart, R; Kendall, DA1

Other Studies

6 other study(ies) available for cyclohexanol and 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea

ArticleYear
PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats.
    British journal of pharmacology, 2007, Volume: 152, Issue:5

    Topics: Allosteric Regulation; Animals; Appetite Depressants; Cell Line; Cell Membrane; Cerebral Cortex; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Eating; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Molecular Structure; Phenylurea Compounds; Piperidines; Pyrazoles; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Saccharomyces cerevisiae; Silicone Elastomers; Sulfur Radioisotopes; Weight Gain

2007
Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.
    British journal of pharmacology, 2013, Volume: 170, Issue:4

    Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Line, Tumor; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Indoles; Kinetics; Ligands; Membrane Potentials; Mice; Phenylurea Compounds; Piperidines; Potassium Channels, Inwardly Rectifying; Protein Transport; Pyridines; Rats; Receptor, Cannabinoid, CB1; Signal Transduction; Transfection

2013
The membrane proximal region of the cannabinoid receptor CB1 N-terminus can allosterically modulate ligand affinity.
    Biochemistry, 2013, Nov-19, Volume: 52, Issue:46

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cyclohexanols; Cysteine; Disulfides; Dithiothreitol; Humans; Indoles; Ligands; Phenylurea Compounds; Piperidines; Pyridines; Rats; Receptor, Cannabinoid, CB1

2013
Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Affinity Labels; Allosteric Site; Animals; Arrestins; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Drug Discovery; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Ligands; Models, Molecular; Phenylurea Compounds; Piperidines; Pyridines; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1; Structure-Activity Relationship

2016
The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB
    Neuropharmacology, 2017, Volume: 125

    Topics: Allosteric Regulation; Animals; Cannabinoid Receptor Modulators; Cerebellum; Cyclohexanols; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice, Inbred C57BL; Mice, Inbred ICR; Motor Activity; Phenylurea Compounds; Piperidines; Pregnenolone; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Rimonabant

2017
Allosteric modulators restore orthosteric agonist binding to mutated CB
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:1

    Topics: Binding Sites; Cannabinoid Receptor Agonists; Cyclohexanols; HEK293 Cells; Humans; Indoles; Ligands; Mutation; Phenylurea Compounds; Piperidines; Protein Binding; Protein Conformation; Pyridines; Receptor, Cannabinoid, CB1; Rimonabant; Structure-Activity Relationship

2020