cycloguanil has been researched along with naphthoquinones in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howells, RE; Percy, M | 1 |
| Howells, RE; Judge, BM | 1 |
| Ager, AL; Canfield, CJ; Jacobus, DP; Lewis, NJ; Milhous, WK; Rossan, RN; Sweeney, TR | 1 |
| Christopherson, RI; Rieckmann, KH; Seymour, KK; Yeo, AE | 1 |
| Gillotin, C; Mamet, JP; Veronese, L | 1 |
| Ashton, M; Bergqvist, Y; Björkman, A; Johansson, I; Lindegårdh, N; Nivelius, S; Thapar, MM | 1 |
| Alifrangis, M; Jelinek, T; Salanti, A; Schwöbel, B | 1 |
| Bienzle, U; Ehrhardt, S; Jelinek, T; Mockenhaupt, FP; Muehlen, M; Otchwemah, R; Schreiber, J | 1 |
| Björkman, A; Gil, JP; Thapar, MM | 1 |
| Kioy, D; Konsil, J; Manyando, C; Miller, GB; Mulenga, M; Na-Bangchang, K; Ruengweerayut, R | 1 |
| Jiang, S; McConkey, GA; McRobert, L; Stead, A | 1 |
| Kamau, EM; Nduati, EW | 1 |
3 trial(s) available for cycloguanil and naphthoquinones
| Article | Year |
|---|---|
Lack of a pharmacokinetic interaction between atovaquone and proguanil.
Topics: Adult; Antimalarials; Atovaquone; Cross-Over Studies; Drug Interactions; Female; Humans; Male; Naphthoquinones; Proguanil; Sex Factors; Triazines | 1999 |
Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.
Topics: Adult; Antimalarials; Atovaquone; Biological Availability; Dose-Response Relationship, Drug; Drug Combinations; Female; Genotype; Humans; In Vitro Techniques; Male; Middle Aged; Naphthoquinones; Phenotype; Proguanil; Time Factors; Triazines | 2002 |
The pharmacokinetics and pharmacodynamics of atovaquone and proguanil for the treatment of uncomplicated falciparum malaria in third-trimester pregnant women.
Topics: Adolescent; Adult; Antimalarials; Atovaquone; Drug Combinations; Female; Humans; Malaria, Falciparum; Naphthoquinones; Pregnancy; Proguanil; Thailand; Triazines; Zambia | 2005 |
9 other study(ies) available for cycloguanil and naphthoquinones
| Article | Year |
|---|---|
The interaction of the naphthoquinone derivative menoctone and dihydrofolate reductase inhibitors on Plasmodium falciparum in vitro.
Topics: Animals; Antiprotozoal Agents; Drug Interactions; Folic Acid Antagonists; Hypoxanthines; Naphthoquinones; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 1986 |
Sustained-release implants in the chemotherapy of experimental rodent malaria I. A comparison of the effects of some antimalarials in polydimethylsiloxane matrices.
Topics: Animals; Antimalarials; Chloroquine; Dimethylpolysiloxanes; Drug Implants; Malaria; Male; Mefloquine; Mice; Mice, Inbred Strains; Naphthoquinones; Piperidines; Plasmodium berghei; Primaquine; Proguanil; Pyrimethamine; Quinolines; Silicone Elastomers; Sulfadiazine; Triazines | 1981 |
PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.
Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Atovaquone; Drug Synergism; Folic Acid Antagonists; Imides; Injections, Subcutaneous; Malaria, Falciparum; Mice; Naphthoquinones; Phenyl Ethers; Plasmodium falciparum; Proguanil; Sulfamethoxazole; Triazines | 1993 |
Effects of folic and folinic acids in the activities of cycloguanil and WR99210 against Plasmodium falciparum in erythrocytic culture.
Topics: Animals; Antimalarials; Atovaquone; Drug Interactions; Folic Acid; Humans; Leucovorin; Naphthoquinones; Plasmodium falciparum; Proguanil; Purine Nucleotides; Pyrimethamine; Pyrimidine Nucleotides; Triazines | 1997 |
Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Atovaquone; Codon; Drug Resistance; Electron Transport Complex III; Genetic Markers; Humans; Malaria, Falciparum; Mutation; Naphthoquinones; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proguanil; Triazines | 2003 |
Short communication: Prevalence of mutations associated with resistance to atovaquone and to the antifolate effect of proguanil in Plasmodium falciparum isolates from northern Ghana.
Topics: Animals; Antimalarials; Atovaquone; Child, Preschool; Cytochromes b; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid Antagonists; Ghana; Humans; Infant; Malaria, Falciparum; Male; Mutation; Naphthoquinones; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Proguanil; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Triazines | 2004 |
In vitro recrudescence of Plasmodium falciparum parasites suppressed to dormant state by atovaquone alone and in combination with proguanil.
Topics: Animals; Antimalarials; Atovaquone; Culture Media; Cytochrome b Group; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Recurrence; Triazines | 2005 |
Plasmodium falciparum: interaction of shikimate analogues with antimalarial drugs.
Topics: Animals; Antimalarials; Atovaquone; Drug Interactions; Naphthoquinones; Plasmodium falciparum; Proguanil; Pyrimethamine; Shikimic Acid; Triazines | 2005 |
Multiple synergistic interactions between atovaquone and antifolates against Plasmodium falciparum in vitro: a rational basis for combination therapy.
Topics: Animals; Antimalarials; Atovaquone; Dapsone; Drug Synergism; Drug Therapy, Combination; Folic Acid Antagonists; Naphthoquinones; Plasmodium falciparum; Proguanil; Triazines | 2006 |