Page last updated: 2024-08-20

cycloguanil and chlorproguanil

cycloguanil has been researched along with chlorproguanil in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (36.36)	18.7374
1990's	3 (27.27)	18.2507
2000's	3 (27.27)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
González-Ruiz, A; Haworth, SJ; O'Neil, AB; Warhurst, DC	1
Björkman, A; Flachs, H; Hanson, AP; Hvidberg, EF; Høgh, B; Petersen, E	1
Bjorkman, A; Flacks, H; Hanson, AP; Hogh, B; Petersen, E	1
Flachs, H; Hanson, AP; Høgh, B; Petersen, E	1
Edstein, MD; Rieckmann, KH; Veenendaal, JR	1
Barutwanayo, M; Coosemans, MH; Gryseels, B; Onori, E; Otoul, C; Wéry, M	1
Edstein, MD; Veenendaal, JR	1
Peters, W; Robinson, BL; Stewart, LB	1
Kamau, EM; Nduati, EW	1
Aarons, L; Bojang, K; Edwards, G; Hughes, D; Manyando, C; Simpson, JA; Ward, S; Watkins, WA; Winstanley, P	1

Trials

1 trial(s) available for cycloguanil and chlorproguanil

Article	Year
Double-blind study to assess the efficacy of chlorproguanil given alone or in combination with chloroquine for malaria chemoprophylaxis in an area with Plasmodium falciparum resistance to chloroquine, pyrimethamine and cycloguanil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:1 Topics: Adolescent; Animals; Antimalarials; Child; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines	1987

Article

Year

Double-blind study to assess the efficacy of chlorproguanil given alone or in combination with chloroquine for malaria chemoprophylaxis in an area with Plasmodium falciparum resistance to chloroquine, pyrimethamine and cycloguanil.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:1

Topics: Adolescent; Animals; Antimalarials; Child; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines

1987

Other Studies

10 other study(ies) available for cycloguanil and chlorproguanil

Article	Year
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Dapsone in low doses prevents Pneumocystis carinii pneumonia in the rat model. The Journal of infection, 1991, Volume: 22, Issue:2 Topics: Administration, Oral; Animals; Dapsone; Diet; Disease Models, Animal; Immune Tolerance; Male; Pneumonia, Pneumocystis; Proguanil; Random Allocation; Rats; Rats, Inbred Strains; Triazines	1991
Plasma, erythrocyte and urine concentrations of chlorproguanil and two metabolites in man after different doses. The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:3 Topics: Adult; Aged; Antimalarials; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Male; Middle Aged; Proguanil; Triazines	1991
In vitro and in vivo susceptibility of Plasmodium falciparum isolates from Liberia to pyrimethamine, cycloguanil and chlorcycloguanil. Annals of tropical medicine and parasitology, 1990, Volume: 84, Issue:6 Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Liberia; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines	1990
Malaria breakthrough despite chlorproguanil chemoprophylaxis in an area without antifol resistance. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:5 Topics: Animals; Antimalarials; Drug Resistance; Folic Acid Antagonists; Humans; Malaria; Plasmodium falciparum; Proguanil; Triazines	1988
Pharmacokinetics of chlorproguanil in man after a single oral dose of Lapudrine. Chemotherapy, 1988, Volume: 34, Issue:4 Topics: Administration, Oral; Adult; Half-Life; Humans; Male; Metabolic Clearance Rate; Proguanil; Triazines	1988
Chlorproguanil and chlorcycloguanil concentrations in human plasma and urine after Lapudrine administration. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:1 Topics: Adult; Antimalarials; Chromatography, High Pressure Liquid; Half-Life; Humans; Male; Proguanil; Triazines	1987
The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate. Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:8 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Therapy, Combination; Folic Acid Antagonists; Malaria, Falciparum; Male; Mice; Parasitemia; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Proguanil; Sesquiterpenes; Triazines	2004
Multiple synergistic interactions between atovaquone and antifolates against Plasmodium falciparum in vitro: a rational basis for combination therapy. Acta tropica, 2006, Volume: 97, Issue:3 Topics: Animals; Antimalarials; Atovaquone; Dapsone; Drug Synergism; Drug Therapy, Combination; Folic Acid Antagonists; Naphthoquinones; Plasmodium falciparum; Proguanil; Triazines	2006
Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone. British journal of clinical pharmacology, 2006, Volume: 61, Issue:3 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Dapsone; Humans; Infant; Malaria, Falciparum; Middle Aged; Plasmodium falciparum; Proguanil; Prospective Studies; Triazines	2006