cyclocholine has been researched along with choline in 17 studies
| Studies (cyclocholine) | Trials (cyclocholine) | Recent Studies (post-2010) (cyclocholine) | Studies (choline) | Trials (choline) | Recent Studies (post-2010) (choline) |
|---|---|---|---|---|---|
| 17 | 0 | 0 | 19,628 | 608 | 4,345 |
| Protein | Taxonomy | cyclocholine (IC50) | choline (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | 1.6 | |
| High affinity choline transporter 1 | Mus musculus (house mouse) | 1.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jenden, DJ; Macri, JR; Parker, TS | 1 |
| Colhoun, EH; Rylett, BJ | 3 |
| Rylett, RJ | 4 |
| Rylett, RJ; Walters, SA | 1 |
| Baskey, JC; Colhoun, EH; Rylett, RJ | 1 |
| Colhoun, EH; Myles, LA; Rylett, RJ | 1 |
| Colhoun, EH; Rylett, RJ | 2 |
| Allen, MC | 1 |
| Collier, B; Ferguson, SS; Rylett, RJ | 1 |
| Goddard, S; Lambros, A; Rylett, RJ | 1 |
| Davis, W; Rylett, RJ; Walters, SA | 1 |
17 other study(ies) available for cyclocholine and choline
| Article | Year |
|---|---|
A new neuromuscular blocking agent: 1-methyl, 1(2-hydroxyethyl) aziridinium tosylate (cyclocholine).
Topics: Animals; Aziridines; Azirines; Binding Sites; Chemical Phenomena; Chemistry; Choline; Diaphragm; Hemicholinium 3; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Blocking Agents; Phrenic Nerve; Rats; Synaptic Transmission | 1976 |
The interactions of choline mustard aziridinium ion with choline acetyltransferase (EC 2.3.1.6).
Topics: Animals; Aziridines; Azirines; Binding, Competitive; Brain; Choline; Choline O-Acetyltransferase; Drug Stability; Female; Kinetics; Nitrogen Mustard Compounds; Rats | 1979 |
Effects of acetylcholine mustard aziridinium ion and its choline analogue on choline transport into synaptosomes.
Topics: Acetylcholine; Animals; Aziridines; Azirines; Brain; Choline; Depression, Chemical; Female; Hemicholinium 3; In Vitro Techniques; Nitrogen Mustard Compounds; Rats; Sodium; Synaptosomes | 1977 |
Solubilization and partial characterization of [3H]choline mustard-labeled high-affinity choline carrier from presynaptic plasma membrane of Torpedo electric organ.
Topics: Animals; Carrier Proteins; Cell Membrane; Centrifugation, Density Gradient; Cholic Acids; Choline; Chromatography, Gel; Electric Organ; Molecular Weight; Solubility; Torpedo | 1990 |
Uptake and metabolism of [3H]choline mustard by cholinergic nerve terminals from rat brain.
Topics: Animals; Brain; Choline; Female; In Vitro Techniques; Kinetics; Nerve Endings; Nerve Tissue Proteins; Neuromuscular Blocking Agents; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Synaptosomes | 1990 |
Cholinergic but not GABAergic neuronal markers are decreased in primary neuronal cultures treated with choline mustard.
Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Choline; Choline O-Acetyltransferase; DNA; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Neuromuscular Depolarizing Agents; Neurons; Rats | 1990 |
Choline mustard: an irreversible ligand for use in studies of choline transport mechanisms at the cholinergic nerve terminal.
Topics: Animals; Choline; Cholinergic Fibers; Female; In Vitro Techniques; Nerve Endings; Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Synaptosomal "membrane-bound" choline acetyltransferase is most sensitive to inhibition by choline mustard.
Topics: Animals; Brain; Cell Membrane; Choline; Choline O-Acetyltransferase; Cytosol; Female; L-Lactate Dehydrogenase; Naphthylvinylpyridine; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Affinity labelling and identification of the high-affinity choline carrier from synaptic membranes of Torpedo electromotor nerve terminals with [3H]choline mustard.
Topics: Affinity Labels; Animals; Biological Transport; Carrier Proteins; Choline; Electric Organ; Hemicholinium 3; Membrane Proteins; Molecular Weight; Neuromuscular Blocking Agents; Sodium; Synaptic Membranes; Torpedo | 1988 |
An attempt to produce cholinergic hypofunction in rat brain using choline mustard aziridinium ion: neurochemical and histological parameters.
Topics: Alzheimer Disease; Animals; Brain; Choline; Disease Models, Animal; Hippocampus; Male; Nerve Degeneration; Parasympathetic Nervous System; Rats; Rats, Inbred Strains | 1986 |
Studies on the alkylation of choline acetyltransferase by choline mustard aziridinium ion.
Topics: Alkylation; Animals; Brain; Choline; Choline O-Acetyltransferase; Kinetics; Neuromuscular Blocking Agents; Rats; Synaptosomes | 1985 |
The effect of choline mustard on the rat superior cervical ganglia.
Topics: Animals; Choline; Ganglia, Sympathetic; Hemicholinium 3; In Vitro Techniques; Male; Neuromuscular Blocking Agents; Rats; Sodium; Synaptic Transmission | 1983 |
An evaluation of irreversible inhibition of synaptosomal high-affinity choline transport by choline mustard aziridinium ion.
Topics: Animals; Biological Transport; Brain; Choline; Female; Kinetics; Neuromuscular Blocking Agents; Rats; Rats, Inbred Strains; Sodium; Synaptosomes | 1984 |
Carrier-mediated inhibition of choline acetyltransferase.
Topics: Acetylcholine; Animals; Aziridines; Biological Transport; Choline; Choline O-Acetyltransferase; Frontal Lobe; Hemicholinium 3; Nitrogen Mustard Compounds; Rats; Sodium Chloride; Synaptosomes | 1980 |
Regulation of rat brain synaptosomal [3H]hemicholinium-3 binding and [3H]choline transport sites following exposure to choline mustard aziridinium ion.
Topics: Animals; Biological Transport; Brain; Choline; Corpus Striatum; Female; Hemicholinium 3; Hippocampus; Kinetics; Neuromuscular Blocking Agents; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium | 1994 |
Regulation of expression of cholinergic neuronal phenotypic markers in neuroblastoma LA-N-2.
Topics: Acetylcholine; Biological Transport; Biomarkers; Carrier Proteins; Cell Differentiation; Choline; DNA-Directed RNA Polymerases; Humans; Nerve Tissue Proteins; Neuroblastoma; Neurons; Parasympathetic Nervous System; Phenotype; Tumor Cells, Cultured | 1993 |
Identification and partial characterization of the high-affinity choline carrier from rat brain striatum.
Topics: Animals; Carrier Proteins; Choline; Corpus Striatum; Hemicholinium 3; Kinetics; Molecular Weight; Neuromuscular Blocking Agents; Rats; Synaptosomes | 1996 |