cycloastragenol has been researched along with isoproterenol in 2 studies
*Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [MeSH]
*Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [MeSH]
| Studies (cycloastragenol) | Trials (cycloastragenol) | Recent Studies (post-2010) (cycloastragenol) | Studies (isoproterenol) | Trials (isoproterenol) | Recent Studies (post-2010) (isoproterenol) |
|---|---|---|---|---|---|
| 62 | 0 | 55 | 30,780 | 803 | 2,640 |
| Protein | Taxonomy | cycloastragenol (IC50) | isoproterenol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.246 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.333 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 1.77 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.6667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qi, R; Tuerdi, N; Wan, Y; Wang, Y; Xu, L; Ye, M | 1 |
| Cai, H; Cao, SP; Song, YH; Wang, J; Wu, ML; Zhao, ZM | 1 |
2 other study(ies) available for cycloastragenol and isoproterenol
| Article | Year |
|---|---|
Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome.
Topics: Animals; Cardiovascular Diseases; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Fibroblasts; Fibrosis; Heart; Humans; Inflammasomes; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes | 2018 |
Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling.
Topics: Animals; Astragalus propinquus; Autophagy; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Heart Failure; Isoproterenol; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sapogenins; Signal Transduction | 2018 |