Page last updated: 2024-09-04

cycloastragenol and beta-escin

cycloastragenol has been researched along with beta-escin in 12 studies

Compound Research Comparison

Studies
(cycloastragenol)
Trials
(cycloastragenol)
Recent Studies (post-2010)
(cycloastragenol)
Studies
(beta-escin)
Trials
(beta-escin)
Recent Studies (post-2010) (beta-escin)
6205514,1372116,278

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (75.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
He, K; Wang, HK1
Chen, YS; Ruan, M; Yu, B; Zhang, LY; Zhuang, Y1
Chin, AC; Harley, CB; Ho, MK; Hu, Y; Ip, FC; Ip, NY; Lam, WS; Pang, H; Wong, YH; Yung, LY1
Ruan, JQ; Song, YL; Wang, YT; Yan, R; Zhou, RN1
Cao, J; Feng, LM; Guo, DA; Huang, FX; Lin, XH; Qiao, X; Ye, M1
Agra, LC; Barbosa, FT; Barreto, E; Ferro, JN1
Li, J; Li, Q; Liu, B; Liu, K; Sun, Y; Zhang, N; Zhao, W; Zhao, Y1
Chao, L; Han, L; Li, X; Ruan, J; Shi, P; Wang, T; Zhang, Y1
Chen, Y; Wang, L1
Qi, R; Tuerdi, N; Wan, Y; Wang, Y; Xu, L; Ye, M1
Ahmad, S; Choe, K; Ikram, M; Jo, MH; Khan, A; Kim, MO; Kim, MW; Saeed, K1
Fukami, H; Kishino, S; Ogawa, J; Ozeki, Y; Takeuchi, DM1

Reviews

2 review(s) available for cycloastragenol and beta-escin

ArticleYear
[Recent development of chemical studies on some medicinal plants of Astragalus spp].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:11

    Topics: Chemical Phenomena; Chemistry; Drugs, Chinese Herbal; Glucosides; Glycosides; Sapogenins; Saponins; Triterpenes

1988
Triterpenes with healing activity: A systematic review.
    The Journal of dermatological treatment, 2015, Volume: 26, Issue:5

    Topics: Cell Movement; Cell Proliferation; Collagen; Fibroblasts; Ginsenosides; Humans; Keratinocytes; Pentacyclic Triterpenes; Reactive Oxygen Species; Sapogenins; Saponins; Skin; Skin Diseases; Triterpenes; Ursolic Acid; Wound Healing

2015

Other Studies

10 other study(ies) available for cycloastragenol and beta-escin

ArticleYear
[Transformation of astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:3

    Topics: Antioxidants; Astragalus propinquus; Chromatography, High Pressure Liquid; Fermentation; Ganoderma; Molecular Structure; Plant Roots; Plants, Medicinal; Sapogenins; Saponins; Triterpenes

2010
Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types.
    Planta medica, 2012, Volume: 78, Issue:2

    Topics: Astragalus Plant; Brain; Breast; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Lung; Phosphorylation; Plant Extracts; Sapogenins; Saponins; src-Family Kinases; Telomerase; Triterpenes

2012
Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of astragali radix, in traditional oral use of the herb.
    Drug metabolism and pharmacokinetics, 2012, Volume: 27, Issue:6

    Topics: Administration, Oral; Animals; Area Under Curve; Bacteria; Biotransformation; Drugs, Chinese Herbal; Feces; Intestinal Mucosa; Intestines; Male; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes

2012
Smith degradation, an efficient method for the preparation of cycloastragenol from astragaloside IV.
    Fitoterapia, 2014, Volume: 95

    Topics: Acids; Astragalus propinquus; Chromatography, Liquid; Drugs, Chinese Herbal; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Sapogenins; Saponins; Triterpenes

2014
Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium.
    Journal of ethnopharmacology, 2015, Jul-01, Volume: 169

    Topics: Apoptosis; Carrier Proteins; Caspase 3; Cells, Cultured; Endoplasmic Reticulum Stress; Endoribonucleases; Endothelial Cells; Humans; Inflammasomes; Membrane Potential, Mitochondrial; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Sapogenins; Saponins; Triterpenes

2015
Bioactive cyclolanstane-type saponins from the stems of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao.
    Journal of natural medicines, 2016, Volume: 70, Issue:2

    Topics: Astragalus propinquus; Hep G2 Cells; Humans; Hypolipidemic Agents; Plant Extracts; Plant Stems; Sapogenins; Saponins; Triglycerides

2016
Efficient Biotransformation of Astragaloside IV to Cycloastragenol by Bacillus sp. LG-502.
    Applied biochemistry and biotechnology, 2017, Volume: 183, Issue:4

    Topics: Bacillus; Biotransformation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Sapogenins; Saponins; Triterpenes

2017
Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Animals; Cardiovascular Diseases; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Fibroblasts; Fibrosis; Heart; Humans; Inflammasomes; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes

2018
Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions.
    Cells, 2021, 10-11, Volume: 10, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Astrocytes; Brain; Cyclic AMP Response Element-Binding Protein; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Inflammation; Inflammation Mediators; Memory Disorders; Mice, Inbred C57BL; Microglia; Nerve Growth Factors; Nerve Tissue Proteins; Neurodegenerative Diseases; Oxidative Stress; Phosphorylation; Sapogenins; Saponins; Triterpenes

2021
Analysis of astragaloside IV metabolism to cycloastragenol in human gut microorganism, bifidobacteria, and lactic acid bacteria.
    Bioscience, biotechnology, and biochemistry, 2022, Sep-23, Volume: 86, Issue:10

    Topics: Bacteria; Bifidobacterium; Glucose; Humans; Lactobacillales; Sapogenins; Saponins; Triterpenes; Xylose

2022