cyclic-gmp and yessotoxin

cyclic-gmp has been researched along with yessotoxin* in 1 studies

Other Studies

1 other study(ies) available for cyclic-gmp and yessotoxin

Article	Year
Algal toxin yessotoxin signalling pathways involve immunocyte mussel calcium channels. Cell biology international, 2006, Volume: 30, Issue:9 A fragment of a putative L-type Ca(2+) channel has been identified by molecular biology experiments in immunocytes from the mussel Mytilus galloprovincialis. Using the cell permeable and Ca(2+)-specific fluorochrome FURA 2-AM, we have demonstrated that the algal toxin yessotoxin (YTX) is able to increase intracellular Ca(2+) concentration in M. galloprovincialis immunocytes. The YTX effect on Ca(2+) increase is inhibited by the L-type Ca(2+) channel inhibitor, verapamil, which is cAMP- and cGMP-dependent, but PKA- and nitric oxide-independent. On the basis of these observations, a possible role for YTX as a potential disturber of mussel immune efficiency is suggested. Topics: Amino Acid Sequence; Animals; Base Sequence; Bivalvia; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic AMP; Cyclic GMP; Ethers, Cyclic; Eukaryota; Fluorescent Dyes; Fura-2; Molecular Sequence Data; Mollusk Venoms; Oxocins; Signal Transduction; Verapamil	2006

Article

Year

Algal toxin yessotoxin signalling pathways involve immunocyte mussel calcium channels.

Cell biology international, 2006, Volume: 30, Issue:9

A fragment of a putative L-type Ca(2+) channel has been identified by molecular biology experiments in immunocytes from the mussel Mytilus galloprovincialis. Using the cell permeable and Ca(2+)-specific fluorochrome FURA 2-AM, we have demonstrated that the algal toxin yessotoxin (YTX) is able to increase intracellular Ca(2+) concentration in M. galloprovincialis immunocytes. The YTX effect on Ca(2+) increase is inhibited by the L-type Ca(2+) channel inhibitor, verapamil, which is cAMP- and cGMP-dependent, but PKA- and nitric oxide-independent. On the basis of these observations, a possible role for YTX as a potential disturber of mussel immune efficiency is suggested.

Topics: Amino Acid Sequence; Animals; Base Sequence; Bivalvia; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic AMP; Cyclic GMP; Ethers, Cyclic; Eukaryota; Fluorescent Dyes; Fura-2; Molecular Sequence Data; Mollusk Venoms; Oxocins; Signal Transduction; Verapamil

2006