cyclic-gmp and sodium-bromide

In order to find the best method for estimating the dry-weight of hemodialysis (HD) patients, we compared the three methods used, i.e. bioelectrical resistivity (rho), plasma cGMP (cGMP) and bromide (Br) methods. The results showed that the extracellular fluid volume per unit body mass (EFV/mass) determined with rho was negatively correlated with that determined with Br. (r = -0.7601 for normal controls and -0.5293 for HD patients, P < 0.05). However, plasma cGMP concentration was neither correlated with EFV/mass (r = 0.3724 for normal control and 0.2538 for HD patients, P > 0.05) nor with rho (r = 0.5210 for normal controls and 0.2106 for HD patients, P > 0.05). These results suggest that the bioelectrical resistivity dry-weight method is more accurate than cGMP method and moreover it is easier to perform than the NaBr method.

Topics: Adult; Body Fluids; Body Weight; Bromides; Cyclic GMP; Electric Impedance; Extracellular Space; Female; Humans; Leg; Male; Middle Aged; Renal Dialysis; Sodium Compounds