cyclic-gmp and adenosine-triphosphate-adenosine-monophosphate-adenosine-monophosphate

cyclic-gmp has been researched along with adenosine-triphosphate-adenosine-monophosphate-adenosine-monophosphate* in 1 studies

Other Studies

1 other study(ies) available for cyclic-gmp and adenosine-triphosphate-adenosine-monophosphate-adenosine-monophosphate

Article	Year
Study on the mechanism of interferon action (XI)--Effect of pppA2'p5'A on the level of cAMP and cGMP in macrophages. Science in China. Series B, Chemistry, life sciences & earth sciences, 1989, Volume: 32, Issue:8 In this paper, the increase of cellular cAMP and cGMP levels in macrophages induced by ppA2'p5' A2'p5'A (briefly 2'-5'P3A3) is first reported. The optimal concentration of 2'-5' P3A3 for the elevation of cellular cGMP to the highest level is 10(-7)-10(-6) mol/L, while that for cAMP is 10(-7) mol/L. The time for cGMP to reach its peak value is 15 min and that for cAMP is 2 h, when the cells are treated with 2'-5' P3A3 at 10(-7) mol/L, which is the optimal concentration for developing biological effect of macrophages (phagocytosis). These results suggest that cGMP and cAMP may be related to, or may be the mediators for, 2'-5'P3A3 action. Topics: Adenine Nucleotides; Animals; Cyclic AMP; Cyclic GMP; Interferons; Macrophages; Male; Oligoribonucleotides; Rats	1989

Article

Year

Study on the mechanism of interferon action (XI)--Effect of pppA2'p5'A on the level of cAMP and cGMP in macrophages.

Science in China. Series B, Chemistry, life sciences & earth sciences, 1989, Volume: 32, Issue:8

In this paper, the increase of cellular cAMP and cGMP levels in macrophages induced by ppA2'p5' A2'p5'A (briefly 2'-5'P3A3) is first reported. The optimal concentration of 2'-5' P3A3 for the elevation of cellular cGMP to the highest level is 10(-7)-10(-6) mol/L, while that for cAMP is 10(-7) mol/L. The time for cGMP to reach its peak value is 15 min and that for cAMP is 2 h, when the cells are treated with 2'-5' P3A3 at 10(-7) mol/L, which is the optimal concentration for developing biological effect of macrophages (phagocytosis). These results suggest that cGMP and cAMP may be related to, or may be the mediators for, 2'-5'P3A3 action.

Topics: Adenine Nucleotides; Animals; Cyclic AMP; Cyclic GMP; Interferons; Macrophages; Male; Oligoribonucleotides; Rats

1989