Compounds > cyclic adp-ribose

Page last updated: 2024-09-03

cyclic adp-ribose and tacrolimus

cyclic adp-ribose has been researched along with tacrolimus in 11 studies

Compound Research Comparison

Studies (cyclic adp-ribose)	Trials (cyclic adp-ribose)	Recent Studies (post-2010) (cyclic adp-ribose)	Studies (tacrolimus)	Trials (tacrolimus)	Recent Studies (post-2010) (tacrolimus)
758	0	144	17,757	2,319	6,661

Protein Interaction Comparison

Protein	Taxonomy	cyclic adp-ribose (IC50)	tacrolimus (IC50)
Bile salt export pump	Homo sapiens (human)		7.18
Cytochrome P450 3A4	Homo sapiens (human)		0.58
Cytochrome P450 3A5	Homo sapiens (human)		0.385
Serine/threonine-protein kinase mTOR	Homo sapiens (human)		0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1A	Homo sapiens (human)		0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens (human)		0.0148
Splicing factor 3B subunit 3	Homo sapiens (human)		0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)		3.3
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)		3.7

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (9.09)	18.2507
2000's	9 (81.82)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ikehata, F; Kato, I; Nata, K; Noguchi, N; Okamoto, H; Takasawa, S; Tohgo, A; Yonekura, H	1
Hashii, M; Higashida, H; Minabe, Y	1
Bultynck, G; Callewaert, G; De Smedt, H; Missiaen, L; Parys, JB; Rossi, D; Sorrentino, V	1
Campbell, WB; Chen, YF; Li, PL; Tang, WX; Zou, AP	1
Bradley, KN; Currie, S; MacMillan, D; McCarron, JG; Muir, TC	1
Collier, ML; Fleischer, S; Kotlikoff, MI; Mei, QB; Wang, QS; Wang, YX; Xin, HB; Zheng, YM	1
Hattori, T; Irokawa, T; Nara, M; Sasaki, T; Sasamori, K; Shimura, S; Shirato, K; Takasawa, S; Tamada, T	1
Tanizawa, Y; Ueda, K	1
Dohi, T; Kitayama, S; Kitayama, T; Morita, K	1
Ozawa, T	1
Hao, Y; Ji, G; Miao, L; Pan, J; Song, B; Wenzhi, B; Yin, W; Yuan, Z; Zhang, X; Zheng, J	1

Reviews

1 review(s) available for cyclic adp-ribose and tacrolimus

Article	Year
[Glucose intolerance induced by tacrolimus (FK506), cyclosporin A]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2 Topics: Adult; Calcium; Cyclic ADP-Ribose; Cyclosporine; Diabetic Coma; Glucose Intolerance; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; RNA, Messenger; Tacrolimus; Transcription, Genetic	2005

Other Studies

10 other study(ies) available for cyclic adp-ribose and tacrolimus

Article	Year
Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes. The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6 Topics: Adenosine Diphosphate Ribose; Amino Acid Isomerases; Amino Acid Sequence; Animals; Calcium; Carrier Proteins; Cattle; Cyclic ADP-Ribose; DNA-Binding Proteins; Heat-Shock Proteins; Humans; Islets of Langerhans; Mice; Microsomes; Molecular Sequence Data; Rabbits; Rats; Tacrolimus; Tacrolimus Binding Proteins	1997
cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells. The Biochemical journal, 2000, Jan-15, Volume: 345 Pt 2 Topics: Adenosine Diphosphate Ribose; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic ADP-Ribose; Cytosol; Ion Channel Gating; Manganese; Membrane Potentials; Models, Biological; NAD; Neurons; Niacinamide; Nifedipine; Patch-Clamp Techniques; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus	2000
The conserved sites for the FK506-binding proteins in ryanodine receptors and inositol 1,4,5-trisphosphate receptors are structurally and functionally different. The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcium; Calcium Channels; COS Cells; Cyclic ADP-Ribose; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate Receptors; Isoleucine; Leucine; Magnesium; Microsomes; Molecular Sequence Data; Mutation; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sequence Homology, Amino Acid; Tacrolimus; Tacrolimus Binding Proteins; Transfection; Valine	2001
Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Antibodies; Blotting, Western; Calcium; Cattle; Coronary Vessels; Cyclic ADP-Ribose; Ion Channel Gating; Lipid Bilayers; Muscle, Smooth, Vascular; Ryanodine Receptor Calcium Release Channel; Tacrolimus; Tacrolimus Binding Protein 1A	2002
Cyclic ADP-ribose increases Ca2+ removal in smooth muscle. Journal of cell science, 2003, Nov-01, Volume: 116, Issue:Pt 21 Topics: Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Colon; Cyclic ADP-Ribose; Cytoplasm; Electrophysiology; Gene Expression Regulation; Guinea Pigs; Male; Muscle Cells; Muscle, Smooth; Ovum; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Signal Transduction; Tacrolimus; Tacrolimus Binding Proteins	2003
FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells. American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:3 Topics: Acetylcholine; Animals; Calcium; Chlorides; Cyclic ADP-Ribose; Horses; Immunosuppressive Agents; Membrane Potentials; Mice; Mice, Knockout; Myocytes, Smooth Muscle; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tacrolimus; Tacrolimus Binding Proteins; Trachea	2004
Cyclic ADP-ribose, a putative Ca2+-mobilizing second messenger, operates in submucosal gland acinar cells. American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:1 Topics: Acetylcholine; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Calcium; Cats; Chloride Channels; Cyclic ADP-Ribose; Cytoplasm; Drug Combinations; Electric Conductivity; Humans; Inositol 1,4,5-Trisphosphate; Ion Channels; Membrane Glycoproteins; Microsomes; Respiratory Mucosa; RNA, Messenger; Ryanodine; Second Messenger Systems; Tacrolimus; Trachea	2004
Cyclic ADP-ribose requires FK506-binding protein to regulate intracellular Ca2+ dynamics and catecholamine release in acetylcholine-stimulated bovine adrenal chromaffin cells. Journal of pharmacological sciences, 2006, Volume: 101, Issue:1 Topics: Acetylcholine; Animals; Blotting, Western; Calcium; Calcium Channels; Calcium Signaling; Catecholamines; Cattle; Chromaffin Cells; Cyclic ADP-Ribose; Electrophoresis, Polyacrylamide Gel; Immunosuppressive Agents; Manganese; Ryanodine Receptor Calcium Release Channel; Spectrometry, Fluorescence; Tacrolimus; Tacrolimus Binding Proteins	2006
FK506 induces biphasic Ca2+ release from microsomal vesicles of rat pancreatic acinar cells. International journal of molecular medicine, 2006, Volume: 18, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Male; Microsomes; Myocardium; Pancreas, Exocrine; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Tacrolimus; Time Factors	2006
Ca(2+) release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscle. Cell calcium, 2010, Volume: 47, Issue:5 Topics: Animals; Calcium; Cells, Cultured; Cyclic ADP-Ribose; Mice; Muscle, Smooth; Patch-Clamp Techniques; Ryanodine Receptor Calcium Release Channel; Tacrolimus; Tacrolimus Binding Proteins; Thapsigargin; Urinary Bladder	2010