Page last updated: 2024-09-03

cyclic adp-ribose and caffeine

cyclic adp-ribose has been researched along with caffeine in 62 studies

Compound Research Comparison

Studies (cyclic adp-ribose)	Trials (cyclic adp-ribose)	Recent Studies (post-2010) (cyclic adp-ribose)	Studies (caffeine)	Trials (caffeine)	Recent Studies (post-2010) (caffeine)
758	0	144	25,501	2,393	6,825

Protein Interaction Comparison

Protein	Taxonomy	cyclic adp-ribose (IC50)	caffeine (IC50)
Acetylcholinesterase	Homo sapiens (human)		7.25

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	38 (61.29)	18.2507
2000's	23 (37.10)	29.6817
2010's	1 (1.61)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Currie, KP; Galione, A; Scott, RH; Swann, K	1
Beers, KW; Chini, CC; Chini, EN; Dousa, TP	1
Gerasimenko, O; Petersen, OH; Thorn, P	1
Bunch, TD; Reed, WA; White, KL; Yue, C	1
Baumann, O; Ciriacy-Wantrup, EV; Walz, B; Zimmermann, B	1
Gollan, JL; Lilly, LB	1
Aarhus, R; Graeff, RM; Lee, HC	1
Tanaka, Y; Tashjian, AH	2
Tashjian, AH; Xu, Y	1
Li, G; Rutter, GA; Theler, JM; Wollheim, CB	1
Furuya, Y; Hua, SY; Kuba, K; Nohmi, M; Okamoto, H; Takasawa, S; Tokimasa, T	1
Kline, D; Kline, JT	1
Busa, WB; Galione, A; Gillot, I; McDougall, A; Whitaker, M; Willmott, N	1
Lee, HC	1
McGarry, SJ; Sitsapesan, R; Williams, AJ	1
Galione, A; Smith, PA; Willmott, NJ	1
Clementi, E; Meldolesi, J; Nisticò, G; Riccio, M; Sciorati, C	1
Fenton, AM; Kannan, MS; Prakash, YS; Sieck, GC	1
Muir, SR; Sanders, D	1
Becker, PL; Guo, X; Laflamme, MA	1
Nishiyama, A; Ozawa, T	1
Empson, RM; Galione, A	1
Dohi, T; Kitayama, S; Morita, K	1
Kasai, M; Yamaguchi, N	1
Casteels, R; De Smedt, H; Kunzelmann, K; Maes, K; Missiaen, L; Parys, JB; Sienaert, I; Sipma, H; Vanlingen, S	1
Inui, H; Masuda, W; Miyatake, K; Nakano, Y; Takenaka, S; Tokunaga, M; Tsuyama, S; Yamaji, R	1
Bull, R; Hidalgo, C; Marengo, JJ; Pérez, CF	1
Adebanjo, O; Goldstein, S; Huang, MS; Lai, FA; Lipschitz, DA; Moonga, BS; Zaidi, M	1
Kannan, MS; Prakash, YS; Sieck, GC; Walseth, TF	1
Akagawa, Y; Dohi, T; Imai, Y; Itadani, K; Kitayama, S; Morita, K; Yamaki, H	1
Chini, EN; Dousa, TP; Liang, M	1
Dubé, F; Eckberg, WR; Galione, A; Thomas, TW	1
Burlando, B; Panfoli, I; Viarengo, A	1
Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K	1
Bultynck, G; Casteels, R; De Smedt, H; De Smet, P; Maes, K; Missiaen, L; Parys, JB; Sienaert, I; Zizi, M	1
Brufani, M; Cavallaro, RA; Filocamo, L; Galione, A; Galuppi, A; Genazzani, AA	1
Ozawa, T	1
Chad, JE; Pivovarov, AS; Walker, RJ	1
Gylfe, E; Hellman, B; Tengholm, A	1
Cancela, JM; Gerasimenko, JV; Gerasimenko, OV; Petersen, OH; Tepikin, AV	1
Surroca, A; Wolff, D	1
Cowles, RA; Mulholland, MW; Segura, BJ; Turner, DJ; Zhang, W	1
Dipp, M; Evans, AM	1
Heine, M; Messutat, S; Wicher, D	1
Murayama, T; Ogawa, Y; Shiwa, M	1
Cancela, JM; Galione, A; Petersen, OH; Tepikin, AV; Van Coppenolle, F	1
Jílek, F; Petr, J; Rozinek, J; Tománek, M; Urbánková, D	1
Ito, S; Ohta, T; Wakade, AR; Yonekubo, K	1
Harrison, MD; Li, PL; Zhang, DX	1
Duncan, RS; Hwang, SY; Inokuchi, K; Koulen, P; Ozawa, F; Volpe, P; Westhoff, JH	1
Abercrombie, R; Becker, P; Brose, T	1
Deguchi, R; Itoh, J; Kondoh, E	1
Hosokawa, K; Houchi, H; Ikehara, T; Kashimoto, H; Kinouchi, Y; Kitamura, M; Minakuchi, K; Miyamoto, H; Park, KH; Yamaguchi, H; Yoshizaki, K	1
Chang, JP; Sawisky, GR	1
Li, N; Li, PL; Teggatz, EG; Yi, F; Zhang, AY; Zhang, G; Zou, AP	1
Lam, CM; Ma, ZY; Wong, JT; Wong, YH; Yeung, PK	1
Gaspers, LD; Pierobon, N; Renard-Rooney, DC; Thomas, AP	1
Deguchi, R	1
Dabertrand, F; Fritz, N; Macrez, N; Mironneau, J; Morel, JL	1
Behringer, EJ; Buchholz, JN; Buchholz, NE; Keeney, MG; Leite, LD; Pearce, WJ; Vanterpool, CK; Wilson, SM	1
Bloor-Young, D; Churchill, GC; Lewis, AM; Parkesh, R; Rosen, D; Squires, J; Vasudevan, SR; Waters, G	1

Reviews

1 review(s) available for cyclic adp-ribose and caffeine

Article	Year
Cyclic ADP-ribose, the ryanodine receptor and Ca2+ release. Trends in pharmacological sciences, 1995, Volume: 16, Issue:11 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Calmodulin; Calmodulin-Binding Proteins; Cyclic ADP-Ribose; Ion Channel Gating; Isoenzymes; Muscle Proteins; Radioligand Assay; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sea Urchins	1995

Article

Year

Cyclic ADP-ribose, the ryanodine receptor and Ca2+ release.

Trends in pharmacological sciences, 1995, Volume: 16, Issue:11

Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Calmodulin; Calmodulin-Binding Proteins; Cyclic ADP-Ribose; Ion Channel Gating; Isoenzymes; Muscle Proteins; Radioligand Assay; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sea Urchins

1995

Other Studies

61 other study(ies) available for cyclic adp-ribose and caffeine

Article	Year
Activation of Ca(2+)-dependent currents in cultured rat dorsal root ganglion neurones by a sperm factor and cyclic ADP-ribose. Molecular biology of the cell, 1992, Volume: 3, Issue:12 Topics: Adenosine Diphosphate Ribose; Animals; Animals, Newborn; Barium; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Cricetinae; Cyclic ADP-Ribose; Ganglia, Spinal; Male; Membrane Potentials; Neurons; Proteins; Rats; Rats, Wistar; Ruthenium Red; Spermatozoa; Swine; Tissue Extracts	1992
Specific modulation of cyclic ADP-ribose-induced Ca2+ release by polyamines. The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 1 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Inositol 1,4,5-Trisphosphate; NADP; Ovum; Polyamines; Ryanodine; Sea Urchins; Spermine	1995
Cyclic ADP-ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells. The EMBO journal, 1994, May-01, Volume: 13, Issue:9 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Caffeine; Calcium; Calcium Channels; Cholecystokinin; Cyclic ADP-Ribose; Cytosol; Evoked Potentials; Guanosine 5'-O-(3-Thiotriphosphate); Heparin; Inositol 1,4,5-Trisphosphate; Muscle Proteins; Pancreas; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel	1994
The existence of inositol 1,4,5-trisphosphate and ryanodine receptors in mature bovine oocytes. Development (Cambridge, England), 1995, Volume: 121, Issue:8 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Cattle; Cyclic ADP-Ribose; Female; Fura-2; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Microinjections; Muscle Proteins; Oocytes; Oogenesis; Procaine; Receptors, Cytoplasmic and Nuclear; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel	1995
Caffeine- and ryanodine-sensitive Ca(2+)-induced Ca2+ release from the endoplasmic reticulum in honeybee photoreceptors. The Journal of general physiology, 1995, Volume: 105, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Bees; Birefringence; Caffeine; Calcium; Calcium Oxalate; Cyclic ADP-Ribose; Endoplasmic Reticulum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Microelectrodes; Photic Stimulation; Photoreceptor Cells, Invertebrate; Ryanodine	1995
Ryanodine-induced calcium release from hepatic microsomes and permeabilized hepatocytes. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Caffeine; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclic ADP-Ribose; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Ryanodine; Tetracaine; Time Factors	1995
Sensitization of calcium-induced calcium release by cyclic ADP-ribose and calmodulin. The Journal of biological chemistry, 1995, Apr-21, Volume: 270, Issue:16 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calmodulin; Cattle; Cyclic ADP-Ribose; Microsomes; Ryanodine; Sea Urchins; Sulfonamides	1995
Calmodulin is a selective mediator of Ca(2+)-induced Ca2+ release via the ryanodine receptor-like Ca2+ channel triggered by cyclic ADP-ribose. Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-11, Volume: 92, Issue:8 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channels; Calmodulin; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Drug Interactions; Models, Biological; Muscle Proteins; Ovum; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Subcellular Fractions; Sulfonamides	1995
Cyclic ADP-ribose-induced calcium release in sea urchin egg homogenates is a cooperative process. Biochemistry, 1995, Mar-07, Volume: 34, Issue:9 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Drug Synergism; Female; In Vitro Techniques; Kinetics; Ovum; Sea Urchins; Second Messenger Systems	1995
Ca2+ stores in insulin-secreting cells: lack of effect of cADP ribose. Cell calcium, 1994, Volume: 16, Issue:2 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Cell Membrane Permeability; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Male; Rats; Rats, Wistar; Terpenes; Thapsigargin	1994
Thimerosal potentiates Ca2+ release mediated by both the inositol 1,4,5-trisphosphate and the ryanodine receptors in sea urchin eggs. Implications for mechanistic studies on Ca2+ signaling. The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15 Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dithiothreitol; Female; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Kinetics; Microsomes; Muscle Proteins; Ovum; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Signal Transduction; Thimerosal; Xanthenes	1994
Cyclic ADP-ribose modulates Ca2+ release channels for activation by physiological Ca2+ entry in bullfrog sympathetic neurons. Neuron, 1994, Volume: 12, Issue:5 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Cyclic ADP-Ribose; Ganglia, Sympathetic; Ion Channel Gating; Kinetics; Membrane Potentials; Neurons; Rana catesbeiana; Time Factors	1994
Regulation of intracellular calcium in the mouse egg: evidence for inositol trisphosphate-induced calcium release, but not calcium-induced calcium release. Biology of reproduction, 1994, Volume: 50, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Chloride; Cyclic ADP-Ribose; Female; Fertilization in Vitro; Heparin; Inositol 1,4,5-Trisphosphate; Male; Mice; Ovum; Ryanodine; Thimerosal; Time Factors	1994
Redundant mechanisms of calcium-induced calcium release underlying calcium waves during fertilization of sea urchin eggs. Science (New York, N.Y.), 1993, Jul-16, Volume: 261, Issue:5119 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Female; Fertilization; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Muscle Proteins; Ovum; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Signal Transduction; Thimerosal; Xenopus	1993
Potentiation of calcium- and caffeine-induced calcium release by cyclic ADP-ribose. The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Barium; Caffeine; Calcium; Cations, Divalent; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Drug Synergism; Female; In Vitro Techniques; Kinetics; Ovum; Sea Urchins; Spectrometry, Fluorescence; Strontium	1993
A cADP-ribose antagonist does not inhibit secretagogue-, caffeine- and nitric oxide-induced Ca2+ responses in rat pancreatic beta-cells. Cell calcium, 1995, Volume: 18, Issue:5 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Blockers; Cyclic ADP-Ribose; Ion Transport; Nitric Oxide; Pancreas; Patch-Clamp Techniques; Rats; Rats, Wistar	1995
The type 2 ryanodine receptor of neurosecretory PC12 cells is activated by cyclic ADP-ribose. Role of the nitric oxide/cGMP pathway. The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30 Topics: Adenosine Diphosphate Ribose; Alkaloids; Animals; Biomarkers; Caffeine; Calcium; Calcium Channels; Carbazoles; Cyclic ADP-Ribose; Cyclic GMP; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Indoles; Ionomycin; Muscle Proteins; Neurosecretory Systems; Nitric Oxide; Nitroprusside; PC12 Cells; Penicillamine; Rats; Ryanodine Receptor Calcium Release Channel; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Terpenes; Thapsigargin	1996
Cyclic ADP-ribose stimulates sarcoplasmic reticulum calcium release in porcine coronary artery smooth muscle. The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 2 Topics: Adenosine Diphosphate Ribose; Animals; Arteries; Caffeine; Calcium; Coronary Vessels; Cyclic ADP-Ribose; Heparin; Muscle, Smooth, Vascular; Ryanodine; Sarcoplasmic Reticulum; Swine	1996
Pharmacology of Ca2+ release from red beet microsomes suggests the presence of ryanodine receptor homologs in higher plants. FEBS letters, 1996, Oct-14, Volume: 395, Issue:1 Topics: Adenosine Diphosphate Ribose; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cyclic ADP-Ribose; Heparin; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Microsomes; Muscle Proteins; Procaine; Ryanodine; Ryanodine Receptor Calcium Release Channel; Vegetables	1996
Cyclic ADP-ribose does not regulate sarcoplasmic reticulum Ca2+ release in intact cardiac myocytes. Circulation research, 1996, Volume: 79, Issue:1 Topics: Adenosine Diphosphate Ribose; Aniline Compounds; Animals; Caffeine; Calcium; Calmodulin; Cyclic ADP-Ribose; Fluorescent Dyes; Myocardium; Ovum; Patch-Clamp Techniques; Photolysis; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sea Urchins; Xanthenes	1996
Characterization of ryanodine-sensitive Ca2+ release from microsomal vesicles of rat parotid acinar cells: regulation by cyclic ADP-ribose. The Journal of membrane biology, 1997, Apr-01, Volume: 156, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Heparin; Inositol 1,4,5-Trisphosphate Receptors; Male; Microsomes; Muscle Proteins; Parotid Gland; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	1997
Cyclic ADP-ribose enhances coupling between voltage-gated Ca2+ entry and intracellular Ca2+ release. The Journal of biological chemistry, 1997, Aug-22, Volume: 272, Issue:34 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Cell Compartmentation; Cells, Cultured; Cyclic ADP-Ribose; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Membrane Potentials; Mice; Muscle Proteins; Neurons; Rats; Ryanodine Receptor Calcium Release Channel	1997
Stimulation of cyclic ADP-ribose synthesis by acetylcholine and its role in catecholamine release in bovine adrenal chromaffin cells. The Journal of biological chemistry, 1997, Aug-22, Volume: 272, Issue:34 Topics: Acetylcholine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Caffeine; Calcium; Calcium Channel Blockers; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Cyclic ADP-Ribose; Diltiazem; Enzyme Activation; Inositol 1,4,5-Trisphosphate; N-Glycosyl Hydrolases; Ryanodine; Scorpion Venoms; Thapsigargin	1997
Potentiation of depolarization-induced calcium release from skeletal muscle triads by cyclic ADP-ribose and inositol 1,4,5-trisphosphate. Biochemical and biophysical research communications, 1997, Nov-26, Volume: 240, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cell Membrane; Cyclic ADP-Ribose; Electric Stimulation; Electrophysiology; Fluorescent Dyes; Fura-2; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Muscle, Skeletal; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum	1997
Inhibition of inositol trisphosphate-induced calcium release by cyclic ADP-ribose in A7r5 smooth-muscle cells and in 16HBE14o- bronchial mucosal cells. The Biochemical journal, 1998, Feb-01, Volume: 329 ( Pt 3) Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Animals; Aorta; Binding Sites; Bronchi; Caffeine; Calcium; Calcium Channels; Cell Line; Cyclic ADP-Ribose; Epithelial Cells; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mucous Membrane; Muscle, Smooth, Vascular; Rats; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel	1998
Inositol 1,4,5-trisphosphate and cyclic ADP-ribose mobilize Ca2+ in a protist, Euglena gracilis. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cell Cycle; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Drug Interactions; Euglena gracilis; Inositol 1,4,5-Trisphosphate; Microsomes; Phosphodiesterase Inhibitors; Ruthenium Red	1997
Cyclic ADP-ribose activates caffeine-sensitive calcium channels from sea urchin egg microsomes. The American journal of physiology, 1998, Volume: 274, Issue:2 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calmodulin; Cyclic ADP-Ribose; Heparin; In Vitro Techniques; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Lipid Bilayers; Magnesium; Microsomes; Ovum; Ruthenium Red; Sea Urchins; Sulfonamides	1998
Upregulation of functional ryanodine receptors during in vitro aging of human diploid fibroblasts. Biochemical and biophysical research communications, 1998, Apr-07, Volume: 245, Issue:1 Topics: Adenosine Diphosphate Ribose; Antibodies; Caffeine; Calcium; Cellular Senescence; Cyclic ADP-Ribose; Fibroblasts; Fluorescent Antibody Technique; Humans; Microscopy, Fluorescence; Ryanodine Receptor Calcium Release Channel; Up-Regulation	1998
Role of cyclic ADP-ribose in the regulation of [Ca2+]i in porcine tracheal smooth muscle. The American journal of physiology, 1998, Volume: 274, Issue:6 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cyclic ADP-Ribose; Escin; Microscopy, Confocal; Muscle, Smooth; Periodicity; Ruthenium Red; Ryanodine Receptor Calcium Release Channel; Second Messenger Systems; Swine; Trachea	1998
Cyclic ADP-ribose induces Ca2+ release from caffeine-insensitive Ca2+ pools in canine salivary gland cells. Journal of dental research, 1998, Volume: 77, Issue:10 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Cyclic ADP-Ribose; Dogs; Dose-Response Relationship, Drug; Female; Male; Multienzyme Complexes; NAD+ Nucleosidase; Parotid Gland; Phosphodiesterase Inhibitors; Submandibular Gland	1998
Differential effect of pH upon cyclic-ADP-ribose and nicotinate-adenine dinucleotide phosphate-induced Ca2+ release systems. The Biochemical journal, 1998, Nov-01, Volume: 335 ( Pt 3) Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Female; Hydrogen-Ion Concentration; Kinetics; NADP; Oocytes; Sea Urchins; Thimerosal; Tritium	1998
Mechanisms of calcium release and sequestration in eggs of Chaetopterus pergamentaceus. Cell calcium, 1998, Volume: 24, Issue:4 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Extracts; Cyclic ADP-Ribose; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; NADP; Ovum; Polychaeta; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spermatozoa; Thapsigargin; Thimerosal	1998
Cyclic ADP-ribose-dependent Ca2+ release is modulated by free [Ca2+] in the scallop sarcoplasmic reticulum. Biochemical and biophysical research communications, 1999, Apr-02, Volume: 257, Issue:1 Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Aniline Compounds; Animals; Antigens, CD; Antigens, Differentiation; Caffeine; Calcimycin; Calcium; Calcium Signaling; Calmodulin; Cyclic ADP-Ribose; Models, Biological; Mollusca; NAD+ Nucleosidase; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Thapsigargin; Xanthenes	1999
[Role of ryanodine receptors in hydrogen peroxide-induced DNA fragmentation and thymidine incorporation in cultured rat astrocytes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112 Suppl 1 Topics: Adenosine Diphosphate Ribose; Animals; Astrocytes; Caffeine; Calcium; Cell Death; Cells, Cultured; Cyclic ADP-Ribose; DNA Fragmentation; Hydrogen Peroxide; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thymidine	1998
Adenine-nucleotide binding sites on the inositol 1,4,5-trisphosphate receptor bind caffeine, but not adenophostin A or cyclic ADP-ribose. Cell calcium, 1999, Volume: 25, Issue:2 Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Animals; Binding Sites; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Genetic; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Time Factors	1999
Potentiation of cADPR-induced Ca(2+)-release by methylxanthine analogues. Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Drug Evaluation, Preclinical; In Vitro Techniques; Ovum; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Structure-Activity Relationship; Xanthines	1999
Ryanodine-sensitive Ca(2+) release mechanism of rat pancreatic acinar cells is modulated by calmodulin. Biochimica et biophysica acta, 1999, Dec-09, Volume: 1452, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calmodulin; Cells, Cultured; Cyclic ADP-Ribose; Endoplasmic Reticulum; Male; Microsomes; Pancreas; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfonamides	1999
Involvement of ryanodine receptors in EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in helix lucorum identified neurones. Regulatory peptides, 2000, Mar-17, Volume: 88, Issue:1-3 Topics: Acetylcholine; Adenosine; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Aniline Compounds; Animals; Caffeine; Chelating Agents; Cyclic ADP-Ribose; Dantrolene; Egtazic Acid; Fluorescent Dyes; Helix, Snails; Neurons; Neuropeptides; Ryanodine; Ryanodine Receptor Calcium Release Channel; Xanthenes	2000
Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin. Cell calcium, 2000, Volume: 27, Issue:1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Bacterial Toxins; Caffeine; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Cell Membrane Permeability; Cyclic ADP-Ribose; Cytoplasm; Digitonin; Enzyme Inhibitors; Hemolysin Proteins; Inositol 1,4,5-Trisphosphate; Ionophores; Islets of Langerhans; Mice; Mice, Obese; NADP; Organelles; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2000
Two different but converging messenger pathways to intracellular Ca(2+) release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate. The EMBO journal, 2000, Jun-01, Volume: 19, Issue:11 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Cholecystokinin; Cyclic ADP-Ribose; Drug Synergism; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Ion Transport; Mice; NADP; Pancreas; Patch-Clamp Techniques; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel	2000
Inositol 1,4,5-trisphosphate but not ryanodine-receptor agonists induces calcium release from rat liver Golgi apparatus membrane vesicles. The Journal of membrane biology, 2000, Oct-01, Volume: 177, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium Signaling; Calcium-Transporting ATPases; Cyclic ADP-Ribose; Endoplasmic Reticulum; Enzyme Inhibitors; Golgi Apparatus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Liver; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2000
Functional overlap of IP(3)- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:1 Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Anesthetics, Local; Animals; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Cinnarizine; Cyclic ADP-Ribose; Dantrolene; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Microinjections; Muscle Relaxants, Central; Myenteric Plexus; Neurons; Phosphodiesterase Inhibitors; Procaine; Ryanodine	2001
Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ. Circulation research, 2001, Jul-06, Volume: 89, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Cell Hypoxia; Culture Techniques; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Indoles; Kinetics; Lung; Male; Pulmonary Artery; Rats; Rats, Wistar; Ryanodine; Vasoconstriction	2001
Calcium-induced calcium release in neurosecretory insect neurons: fast and slow responses. Cell calcium, 2001, Volume: 30, Issue:3 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Cyclic ADP-Ribose; Electrophysiology; Kinetics; Mitochondria; Neurons, Efferent; Neuropeptides; Patch-Clamp Techniques; Periplaneta; Ruthenium Red; Ryanodine; Spectrometry, Fluorescence; Thapsigargin	2001
Molecular cloning and characterization of ryanodine receptor from unfertilized sea urchin eggs. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3 Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Caffeine; Calcium; Cloning, Molecular; Cyclic ADP-Ribose; DNA, Complementary; Fertilization; Molecular Sequence Data; Multigene Family; Ovum; Phylogeny; Ryanodine Receptor Calcium Release Channel; Sea Urchins	2002
Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers. The EMBO journal, 2002, Mar-01, Volume: 21, Issue:5 Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium Channels; Calcium Signaling; Cell Polarity; Cholecystokinin; Cyclic ADP-Ribose; Exocytosis; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; NADP; Pancreas; Patch-Clamp Techniques; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, Cholinergic; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Sincalide	2002
Activation of in vitro matured pig oocytes using activators of inositol triphosphate or ryanodine receptors. Animal reproduction science, 2002, Apr-15, Volume: 70, Issue:3-4 Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Calcium Channels; Calmodulin; Cell Nucleus; Cyclic ADP-Ribose; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Metaphase; Microinjections; Oocytes; Parthenogenesis; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Swine	2002
Functional relation between caffeine- and muscarine-sensitive Ca2+ stores and no Ca2+ releasing action of cyclic adenosine diphosphate-ribose in guinea-pig adrenal chromaffin cells. Neuroscience letters, 2002, Jul-05, Volume: 326, Issue:3 Topics: Adrenal Glands; Animals; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Chromaffin Cells; Cyclic ADP-Ribose; Dialysis; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Muscarine; Muscarinic Agonists; Patch-Clamp Techniques	2002
Calcium-induced calcium release and cyclic ADP-ribose-mediated signaling in the myocytes from small coronary arteries. Microvascular research, 2002, Volume: 64, Issue:2 Topics: Animals; Caffeine; Calcium; Cattle; Central Nervous System Stimulants; Coronary Vessels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Macrocyclic Compounds; Muscle, Smooth; Myocardium; Oxazoles; Potassium Chloride; Ryanodine; Signal Transduction; Tetracaine; Thapsigargin	2002
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling. Cell calcium, 2003, Volume: 34, Issue:3 Topics: Aniline Compounds; Animals; Binding Sites; Blotting, Western; Caffeine; Calcium; Calcium Signaling; Carrier Proteins; CHO Cells; Cricetinae; Cyclic ADP-Ribose; Dantrolene; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Homer Scaffolding Proteins; Microscopy, Fluorescence; Myocardium; Neuropeptides; Protein Binding; Protein Isoforms; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Transfection; Xanthenes	2003
Ca release induced by cyclic adenosine diphosphoribose (cADPr) in sea urchin egg homogenates: mechanisms of release and heterogeneity of the Ca compartments. Cell calcium, 2005, Volume: 37, Issue:3 Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium Radioisotopes; Calcium Signaling; Cell Compartmentation; Cyclic ADP-Ribose; Kinetics; Magnesium; Ovum; Ryanodine; Sea Urchins	2005
Spatiotemporal characteristics and mechanisms of intracellular Ca(2+) increases at fertilization in eggs of jellyfish (Phylum Cnidaria, Class Hydrozoa). Developmental biology, 2005, Mar-15, Volume: 279, Issue:2 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Cell Polarity; Cyclic ADP-Ribose; Fertilization; Heparin; Hydrozoa; Inositol 1,4,5-Trisphosphate; Microscopy, Fluorescence; Ovum; Phosphodiesterase Inhibitors; Time Factors	2005
Effects of a time-varying strong magnetic field on transient increase in Ca2+ release induced by cytosolic Ca2+ in cultured pheochromocytoma cells. Biochimica et biophysica acta, 2005, Jun-20, Volume: 1724, Issue:1-2 Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Cations, Divalent; Cell Membrane; Cyclic ADP-Ribose; Cytosol; Endoplasmic Reticulum; Hydrolysis; Inositol 1,4,5-Trisphosphate Receptors; Lactic Acid; Magnetics; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Time Factors	2005
Intracellular calcium involvement in pituitary adenylate cyclase-activating polypeptide stimulation of growth hormone and gonadotrophin secretion in goldfish pituitary cells. Journal of neuroendocrinology, 2005, Volume: 17, Issue:6 Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cyclic ADP-Ribose; Dantrolene; Female; Goldfish; Gonadotropins, Pituitary; Growth Hormone; Inositol 1,4,5-Trisphosphate Receptors; Male; Mitochondria; Muscle Relaxants, Central; Neuropeptides; Peptide Fragments; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Receptors, Cytoplasmic and Nuclear; Ryanodine; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Type C Phospholipases	2005
Role of cyclic ADP-ribose in Ca2+-induced Ca2+ release and vasoconstriction in small renal arteries. Microvascular research, 2005, Volume: 70, Issue:1-2 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Male; Microscopy, Confocal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Renal Artery; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Second Messenger Systems; Tacrolimus Binding Proteins; Vasoconstriction	2005
Involvement of calcium mobilization from caffeine-sensitive stores in mechanically induced cell cycle arrest in the dinoflagellate Crypthecodinium cohnii. Cell calcium, 2006, Volume: 39, Issue:3 Topics: Animals; Caffeine; Calcium; Cell Cycle; Chlortetracycline; Cyclic ADP-Ribose; Cytosol; Dinoflagellida; Egtazic Acid; Fluorescent Dyes; Microscopy, Confocal; Ryanodine Receptor Calcium Release Channel; Stress, Mechanical	2006
Ryanodine receptors in liver. The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Central Nervous System Stimulants; Cyclic ADP-Ribose; Cytosol; Dantrolene; Hepatocytes; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Kinetics; Liver; Male; Microinjections; Microsomes; Muscle Relaxants, Central; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel	2006
Fertilization causes a single Ca2+ increase that fully depends on Ca2+ influx in oocytes of limpets (Phylum Mollusca, Class Gastropoda). Developmental biology, 2007, Apr-15, Volume: 304, Issue:2 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Female; Fertilization; Gastropoda; Inositol 1,4,5-Trisphosphate; Male; Meiosis; NADP; Oocytes	2007
Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium. American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:3 Topics: Alternative Splicing; Animals; Caffeine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Female; Gene Expression Regulation; Mice; Myocytes, Smooth Muscle; Myometrium; Oligonucleotides, Antisense; Phosphodiesterase Inhibitors; Pregnancy; Pregnancy, Animal; Ryanodine Receptor Calcium Release Channel	2007
Maturation and long-term hypoxia alters Ca2+-induced Ca2+ release in sheep cerebrovascular sympathetic neurons. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:4 Topics: Age Factors; Aging; Animals; Caffeine; Calcium; Calcium Signaling; Cerebral Arteries; Cyclic ADP-Ribose; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Fetal Hypoxia; Hypoxia; Indoles; Nitric Oxide Synthase Type I; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sheep; Superior Cervical Ganglion; Sympathetic Fibers, Postganglionic; Time Factors	2009
Synthesis and use of cell-permeant cyclic ADP-ribose. Biochemical and biophysical research communications, 2012, Feb-10, Volume: 418, Issue:2 Topics: Animals; Biological Transport; Caffeine; Calcium; Cell Membrane Permeability; Cyclic ADP-Ribose; PC12 Cells; Rats; Ryanodine; Sea Urchins; Thapsigargin	2012